Cytotoxicity and genotoxicity caused by yttrium oxide nanoparticles in HEK293 cells

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 1379-1391

  Selvaraj, Vellaisamy ^a   Bodapati, Sravanthi ^a   Murray, Elizabeth ^b   Rice, Kevin M ^a   Winston, Nicole ^a,c   Shokuhfar, Tolou ^d   Zhao, Yu ^d   Blough, Eric ^a,c,e  

^a Center for Diagnostic Nanosystems   (United States)

^b Department of Integrated Science and Technology ^*  (United States)

^c MARSHALL UNIVERSITY   (United States)

^d Michigan Technological University   (United States)

^e MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Cytotoxicity; DNA damage; Mitochondria damage; Necrosis; ROS production; Yttrium oxide nanoparticles

Indexed keywords

CASPASE 3; DNA; NANOPARTICLE; PARAQUAT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; YTTRIUM OXIDE NANOPARTICLE; METAL NANOPARTICLE; MUTAGENIC AGENT; YTTRIA; YTTRIUM;

APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN HEK293; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DNA DAMAGE; EMBRYO; EXPOSURE; GENOTOXICITY; HUMAN; HUMAN CELL; IC 50; INCUBATION TIME; MEMBRANE STRUCTURE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; NECROSIS; PARTICLE SIZE; PROTEIN EXPRESSION; CELL DEATH; CHROMOSOMAL INSTABILITY; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM; NANOMEDICINE; ULTRASTRUCTURE;

CELL DEATH; CHROMOSOMAL INSTABILITY; DNA DAMAGE; HEK293 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; METAL NANOPARTICLES; MUTAGENS; NANOMEDICINE; PARAQUAT; REACTIVE OXYGEN SPECIES; YTTRIUM;

EID: 84896056159     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S52625     Document Type: Article

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