Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 271, Issue 6 40-6, 1996, Pages

  Stonestreet, Barbara S ^a   Patlak, Clifford S ^b   Pettigrew, Karen D ^b   Reilly, Christopher B ^b   Cserr, Helen F ^b  

^a BROWN UNIVERSITY   (United States)

^b NONE

Author keywords

blood brain barrier permeability; brain; sheep; aminoisobutyric acid

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; FEMALE; FETUS; LAMB; MEMBRANE PERMEABILITY; NONHUMAN; ONTOGENY; POTASSIUM TRANSPORT; PREGNANCY; PRIORITY JOURNAL; SHEEP;

EID: 0030470664     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.271.6.r1594     Document Type: Article

References (35)

1. Andrew, D. L. E., and J. A. Paterson. Postnatal development of vascularity in the inferior colliculus of the young rat. Am. J. Anat. 186: 389-396, 1989.
2. Bar, T. Morphometric evaluation of capillaries in different laminae of rat cerebral cortex by automatic image analysis: changes during development and aging. Adv. Neurol. 20: 1-9, 1978.
3. Betz, A. L., and G. W. Goldstein. Specialized properties and solute transport in brain capillaries. Annu. Rev. Physiol. 48: 241-250, 1986.
4. Blasberg, R. G., J. D. Fenstermacher, and C. S. Patlak. Transport of α-aminoisobutyric acid across brain capillary and cellular membranes. J. Cereb. Blood. Flow. Metab. 3: 8-32, 1983.
5. Blasberg, R. G., and A. Lajtha. Substrate specificity of steady state amino acid transport in mouse brain slices. Arch. Biochem. Biophys. 112: 361-377, 1965.
6. Blasberg, R. G., and A. Lajtha. Heterogeneity of the mediated transport system of amino acid uptake in brain. Brain Res. 1: 86-104, 1966.
7. Bradbury, M. The blood-brain barrier during the development of the individual and evolution of the phylum. In: The Concept of a Blood-Brain Barrier, edited by M. Bradbury. New York: Wiley, 1979, p.289-322.
8. Bradbury, M. W. B. The blood-brain barrier, transport across the cerebral endothelium. Circ. Res. 57: 213-222, 1985.
9. Brightman, M. W., and T. S. Reese. Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40: 648-677, 1969.
10. Cserr, H. F., M. DePasquale, and C. S. Patlak. Volume regulatory influx of electrolytes from plasma to brain during acute hyperosmolality. Am. J. Physiol. 253 (Renal Fluid Electrolyte Physiol. 22): F530-F537, 1987.
11. Dobbing, J., and J. Sands. Comparative aspects of the brain growth spurt. Early Hum. Dev. 3/1: 79-83, 1979.
12. Evans, C. A. N., J. M. Reynolds, M. L. Reynolds, N. R. Saunders, and M. B. Segal. The development of a blood-brain barrier mechanism in foetal sheep. J. Physiol. Lond. 238: 371-386, 1974.
13. Farrell, C. L., and W. Risau. Normal and abnormal development of the blood-brain barrier. Microsc. Res. Tech. 27: 495-506, 1994.
14. Fenstermacher, J. D. Volume regulation of central nervous system. In: Edema, edited by N. C. Staub and A. E. Taylor. New York: Raven, 1984, p. 383-404.
15. 14C-sucrose into brain, cerebrospinal fluid and skeletal muscle of developing rats. Exp. Brain Res. 7: 181-194, 1989.
16. Fuglsang, A., M. Lomholt, and A. Gjedde. Blood-brain transfer of glucose and glucose analogs in newborn rats. J. Neurochem. 46: 1417-1428, 1986.
17. Gleason, C. A., C. Hamm, and M. D. Jones, Jr. Cerebral blood flow, oxygenation, and carbohydrate metabolism in immature fetal sheep in utero. Am. J. Physiol. 256 (Regulatory Integrative Comp. Physiol. 25): R1264-R1268, 1989.
18. Harik, S. I., and R. N. Kalaria. The blood-brain barrier: a selective overview. Cerebrovasc. Dis. 43: 407-410, 1989.
19. Keep, R. F., S. R. Ennis, M. E. Beer, and A. L. Betz. Developmental changes in blood-brain barrier potassium permeability in the rat: relation to brain growth. J. Physiol. Lond. 488: 439-448, 1995.
20. Lucchesi, K. J., and R. E. Gosselin. Mechanism of L-glucose, raffinose, and insulin transport across intact blood-brain barriers. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H695-H705, 1990.
21. Mirro, R., W. M. Armstead, D. W. Busija, and C. W. Leffler. Blood to brain transport after newborn cerebral ischemia/ reperfusion injury. Soc. Exp. Biol. Med. 197: 268-272, 1991.
22. Ohno, K., K. D. Pettigrew, and S. I. Rapoport. Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am. J. Physiol. 235 (Heart Circ. Physiol. 4): H299-H307, 1978.
23. Oldendorf, W. H. Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. Am. J. Physiol. 221: 1629-1639, 1971.
24. 14C]urea. Am. J. Physiol. 243 (Regulatory Integrative Comp. Physiol. 12): R400-R407, 1982.
25. Risau, W., and W. Hartwig. Development of blood-brain barrier. Trends Neurosci. 13: 174-178, 1990.
26. Risau, W., and H. Wolburg. The importance of the blood-brain barrier in fetuses and embryos: reply (Letter). Trends Neurosci. 14: 15, 1991.
27. Saunders, N. R., and K. Mollgard. The importance of the blood-brain barrier in fetuses and embryos. Trends Neurosci. 14: 14, 1991.
28. 14C]iodoantipyrine. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1585-H1598, 1990.
29. Schleien, C. L., R. C. Koehler, D. H. Shaffner, B. Eberle, and R. J. Traystman. Blood-brain barrier disruption after cardiopulmonary resuscitation in immature swine. Stroke 22: 477-483, 1991.
30. Schleien, C. L., R. C. Koehler, D. H. Shaffner, and R. J. Traystman. Blood-brain barrier integrity during cardiopulmonary resuscitation in dogs. Stroke 21: 1185-1191, 1990.
31. 3H]-mannitol uptake into the in vivo choroid plexus-cerebrospinal fluid brain system: ontogeny of the blood-brain and blood-CSF barriers. Dev. Brain Res. 3: 181-198, 1982.
32. Stewart, P. A., and E. M. Hayakawa. Interendothelial junctional changes underlie the developmental "tightening" of the blood-brain barrier. Dev. Brain Res. 32: 271-281, 1987.
33. Stonestreet, B. S., G. H. Burgess, and H. F. Cserr. Blood-brain barrier integrity and brain water and electrolytes during hypoxia/hypercapnia and hypotension in newborn piglets. Brain Res. 590: 263-270, 1992.
34. Stonestreet, B. S., E. Le, and D. J. Berard. Circulatory and metabolic effects of β-adrenergic blockade in the hyperinsulinemic ovine fetus. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H1098-H1106, 1993.
35. Tuor, U. I., C. Simone, and S. Bascaramurty. Local blood-brain barrier in the newborn rabbit: postnatal changes in α-aminoisobutyric acid transfer within medulla, cortex, and selected brain areas. J. Neurochem. 59: 999-1007, 1992.