-
1
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao, W. & Girard, N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 12, 175-80 (2011)
-
(2011)
Lancet Oncol
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
3
-
-
15944404601
-
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
-
Deininger, M., Buchdunger, E. & Druker, B. J. The development of imatinib as a therapeutic agent for chronic myeloid leukemia. Blood 105, 2640-53 (2005)
-
(2005)
Blood
, vol.105
, pp. 2640-2653
-
-
Deininger, M.1
Buchdunger, E.2
Druker, B.J.3
-
4
-
-
33947328520
-
Oncogenes in myeloproliferative disorders
-
Tefferi, A. &Gilliland, D. G. Oncogenes in myeloproliferative disorders. Cell Cycle 6, 550-66 (2007)
-
(2007)
Cell Cycle
, vol.6
, pp. 550-566
-
-
Tefferi, A.1
Gilliland, D.G.2
-
5
-
-
79952824314
-
Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: Approaches for targeted therapies
-
Jatiani, S. S., Baker, S. J., Silverman, L. R. & Reddy, E. P. Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies. Genes Cancer 1, 979-93 (2010)
-
(2010)
Genes Cancer
, vol.1
, pp. 979-993
-
-
Jatiani, S.S.1
Baker, S.J.2
Silverman, L.R.3
Reddy, E.P.4
-
6
-
-
84858855487
-
JAK inhibitors for myeloproliferative neoplasms: Clarifying facts from myths
-
Tefferi, A. JAK inhibitors for myeloproliferative neoplasms: clarifying facts from myths. Blood 119, 2721-30 (2012)
-
(2012)
Blood
, vol.119
, pp. 2721-2730
-
-
Tefferi, A.1
-
7
-
-
78649584257
-
Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-gamma
-
Gordon, G. M., Lambert, Q. T., Daniel, K. G. & Reuther, G. W. Transforming JAK1 mutations exhibit differential signalling, FERM domain requirements and growth responses to interferon-gamma. Biochem J 432, 255-65 (2010)
-
(2010)
Biochem J
, vol.432
, pp. 255-265
-
-
Gordon, G.M.1
Lambert, Q.T.2
Daniel, K.G.3
Reuther, G.W.4
-
8
-
-
56849100624
-
IFN inducibility of major histocompatibility antigens in tumors
-
Seliger, B., Ruiz-Cabello, F. & Garrido, F. IFN inducibility of major histocompatibility antigens in tumors. Adv Cancer Res 101, 249-76 (2008)
-
(2008)
Adv Cancer Res
, vol.101
, pp. 249-276
-
-
Seliger, B.1
Ruiz-Cabello, F.2
Garrido, F.3
-
9
-
-
0037479853
-
IFN-gamma induces apoptosis in ovarian cancer cells in vivo and in vitro
-
Wall, L., Burke, F., Barton, C., Smyth, J. & Balkwill, F. IFN-gamma induces apoptosis in ovarian cancer cells in vivo and in vitro. Clin Cancer Res 9, 2487-96 (2003)
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2487-2496
-
-
Wall, L.1
Burke, F.2
Barton, C.3
Smyth, J.4
Balkwill, F.5
-
10
-
-
0032560475
-
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
-
Kaplan, D. H. et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A 95, 7556-61 (1998)
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
-
11
-
-
0842266786
-
Interferon-gamma: An overview of signals, mechanisms and functions
-
Schroder, K., Hertzog, P. J., Ravasi, T. & Hume, D. A. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75, 163-89 (2004)
-
(2004)
J Leukoc Biol
, vol.75
, pp. 163-189
-
-
Schroder, K.1
Hertzog, P.J.2
Ravasi, T.3
Hume, D.A.4
-
12
-
-
0028927841
-
Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter
-
Wright, K. L. et al. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J Exp Med 181, 1459-71 (1995)
-
(1995)
J Exp Med
, vol.181
, pp. 1459-1471
-
-
Wright, K.L.1
-
13
-
-
0027214605
-
Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes
-
Gaczynska, M., Rock, K. L. & Goldberg, A. L. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature 365, 264-7 (1993)
-
(1993)
Nature
, vol.365
, pp. 264-267
-
-
Gaczynska, M.1
Rock, K.L.2
Goldberg, A.L.3
-
14
-
-
0036141520
-
Development of spontaneous uterine tumors in low molecular mass polypeptide-2 knockout mice
-
Hayashi, T.&Faustman, D. L. Development of spontaneous uterine tumors in low molecular mass polypeptide-2 knockout mice. Cancer Res 62, 24-7 (2002)
-
(2002)
Cancer Res
, vol.62
, pp. 24-27
-
-
Hayashi, T.1
Faustman, D.L.2
-
15
-
-
84859760026
-
Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy
-
Hayashi, T. et al. Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy. Sci Rep 1, 180 (2011)
-
(2011)
Sci Rep
, vol.1
, pp. 180
-
-
Hayashi, T.1
-
16
-
-
83755174099
-
Implementing personalized medicine in a cancer center
-
Fenstermacher, D. A., Wenham, R. M., Rollison, D. E. & Dalton, W. S. Implementing personalized medicine in a cancer center. Cancer J 17, 528-36 (2011)
-
(2011)
Cancer J
, vol.17
, pp. 528-536
-
-
Fenstermacher, D.A.1
Wenham, R.M.2
Rollison, D.E.3
Dalton, W.S.4
-
17
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina, J. et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483, 603-7 (2012)
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
-
18
-
-
1042302005
-
The STATs of cancer-new molecular targets come of age
-
Yu, H. & Jove, R. The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 4, 97-105 (2004)
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
19
-
-
0028147121
-
Homozygous human TAP peptide transporter mutation in HLA class i deficiency
-
de la Salle, H. et al. Homozygous human TAP peptide transporter mutation in HLA class I deficiency. Science 265, 237-41 (1994)
-
(1994)
Science
, vol.265
, pp. 237-241
-
-
De La Salle, H.1
-
20
-
-
0027050452
-
TAP1 mutant mice are deficient in antigen presentation, surface class i molecules, and CD4-81 T cells
-
Van Kaer, L., Ashton-Rickardt, P. G., Ploegh, H. L. & Tonegawa, S. TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-81 T cells. Cell 71, 1205-14 (1992)
-
(1992)
Cell
, vol.71
, pp. 1205-1214
-
-
Van Kaer, L.1
Ashton-Rickardt, P.G.2
Ploegh, H.L.3
Tonegawa, S.4
-
21
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
Kandoth, C. et al. Integrated genomic characterization of endometrial carcinoma. Nature 497, 67-73 (2013)
-
(2013)
Nature
, vol.497
, pp. 67-73
-
-
Kandoth, C.1
-
22
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li, H. &Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-60 (2009)
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
23
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data
-
DePristo, M. A. et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet 43, 491-8 (2011)
-
(2011)
Nat Genet
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
-
24
-
-
77956534324
-
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
-
Wang, K., Li, M. & Hakonarson, H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res 38, e164 (2010)
-
(2010)
Nucleic Acids Res
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
25
-
-
79956307251
-
Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads
-
Lunter, G. & Goodson, M. Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads. Genome Res 21, 936-9 (2011)
-
(2011)
Genome Res
, vol.21
, pp. 936-939
-
-
Lunter, G.1
Goodson, M.2
-
26
-
-
68549104404
-
The Sequence Alignment/Map format and SAMtools
-
Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-9 (2009)
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
-
27
-
-
0032486476
-
Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway
-
Cunnick, J. M. et al. Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway. J Biol Chem 273, 14468-75 (1998)
-
(1998)
J Biol Chem
, vol.273
, pp. 14468-14475
-
-
Cunnick, J.M.1
-
28
-
-
84867417506
-
MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog
-
Xu, C. X. et al. MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog. J Biol Chem 287, 34970-8 (2012)
-
(2012)
J Biol Chem
, vol.287
, pp. 34970-34978
-
-
Xu, C.X.1
-
29
-
-
79952939147
-
Critical role of Shp2 in tumor growth involving regulation of c-Myc
-
Ren, Y. et al. Critical role of Shp2 in tumor growth involving regulation of c-Myc. Genes Cancer 1, 994-1007 (2010)
-
(2010)
Genes Cancer
, vol.1
, pp. 994-1007
-
-
Ren, Y.1
-
30
-
-
37549019323
-
Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL
-
Ren, Y. et al. Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL. J Biol Chem 282, 36463-73 (2007)
-
(2007)
J Biol Chem
, vol.282
, pp. 36463-36473
-
-
Ren, Y.1
|