메뉴 건너뛰기




Volumn 1, Issue , 2011, Pages

Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy

(15)  Hayashi, Takuma a,k   Horiuchi, Akiko b   Sano, Kenji c   Hiraoka, Nobuyoshi d   Kasai, Mari e   Ichimura, Tomoyuki e   Sudo, Tamotsu f   Tagawa, Yoh Ichi g   Nishimura, Ryuichiro f   Ishiko, Osamu e   Kanai, Yae d   Yaegashi, Nobuo h   Aburatani, Hiroyuki i   Shiozawa, Tanri b   Konishi, Ikuo j  


Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; GAMMA INTERFERON; LMP 2 PROTEIN; LMP-2 PROTEIN;

EID: 84859760026     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00180     Document Type: Article
Times cited : (30)

References (61)
  • 3
    • 0030744043 scopus 로고    scopus 로고
    • Uterine sarcomas in Norway 1956-1992: Incidence, survival and mortality
    • Nordal, R. & Thoresen, S. Uterine sarcomas in Norway 1956-1992: incidence, survival and mortality. Eur. J. Cancer 33, 907-311 (1997).
    • (1997) Eur. J. Cancer , vol.33 , pp. 907-311
    • Nordal, R.1    Thoresen, S.2
  • 4
    • 1842425382 scopus 로고    scopus 로고
    • Surveillance, Epidemiology, and End Results analysis of 2677 cases of uterine sarcoma 1989-1999
    • DOI 10.1016/j.ygyno.2003.12.029, PII S0090825803009405
    • Brooks, S. E., Zhan, M., Cote, T. & Baquet, C. R. Surveillance, epidemiology, and end results analysis of 2677 cases of uterine sarcoma 1989-1999. Gynecol. Oncol. 93, 204-208 (2004). (Pubitemid 38429571)
    • (2004) Gynecologic Oncology , vol.93 , Issue.1 , pp. 204-208
    • Brooks, S.E.1    Zhan, M.2    Cote, T.3    Baquet, C.R.4
  • 5
    • 20444420484 scopus 로고    scopus 로고
    • On the apparent failure of adjuvant pelvic radiotherapy to improve survival for women with uterine sarcomas confined to the uterus
    • DOI 10.1097/01.coc.0000156919.04133.98
    • Dusenbery, K. E., Potish, R. A., Argenta, P. A. & Judson, P. L. On the apparent failure of adjuvant pelvic radiotherapy to improve survival for women with uterine sarcomas confined to the uterus. Am. J. Clin. Oncol. 28, 295-300 (2005). (Pubitemid 40800483)
    • (2005) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.28 , Issue.3 , pp. 295-300
    • Dusenbery, K.E.1    Potish, R.A.2    Argenta, P.A.3    Judson, P.L.4
  • 6
    • 29144433592 scopus 로고    scopus 로고
    • Prognostic factors and impact of adjuvant chemotherapy for uterine leiomyosarcoma
    • Wu, T. I., et al. Prognostic factors and impact of adjuvant chemotherapy for uterine leiomyosarcoma. Gynecol. Oncol. 100, 166-172 (2006).
    • (2006) Gynecol. Oncol , vol.100 , pp. 166-172
    • Wu, T.I.1
  • 8
    • 5644276382 scopus 로고    scopus 로고
    • Improving patient care through molecular diagnostics
    • DOI 10.1053/j.seminoncol.2004.07.017, PII S0093775404003641
    • Perez, E. A., Pusztai, L. & Van de Vijver, M. Improving patient care through molecular diagnostics. Semin. Oncol. 31, 14-20 (2004). (Pubitemid 39370105)
    • (2004) Seminars in Oncology , vol.31 , Issue.SUPPL. 10 , pp. 14-20
    • Perez, E.A.1    Pusztai, L.2    Van De Vijver, M.3
  • 11
    • 33645074939 scopus 로고    scopus 로고
    • Evaluation of biological potential of smooth muscle tumours
    • Miettinen, M. & Fetsch, J. F. Evaluation of biological potential of smooth muscle tumours. Histopathology 48, 97-105 (2006).
    • (2006) Histopathology , vol.48 , pp. 97-105
    • Miettinen, M.1    Fetsch, J.F.2
  • 12
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel, T., et al. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nature Med. 15, 781-788 (2009).
    • (2009) Nature Med , vol.15 , pp. 781-788
    • Muchamuel, T.1
  • 13
    • 0028519275 scopus 로고
    • Altered peptidase and viral-specifi c T cell response in LMP2 mutant mice
    • Van Kaer, L. et al. Altered peptidase and viral-specifi c T cell response in LMP2 mutant mice. Immunity 1, 533-541 (1994).
    • (1994) Immunity , vol.1 , pp. 533-541
    • Van Kaer, L.1
  • 14
    • 0036141520 scopus 로고    scopus 로고
    • Development of spontaneous uterine tumors in low molecular mass polypeptide-2 knockout mice
    • Hayashi, T. & Faustman, D. L. Development of spontaneous uterine tumors in low molecular mass polypeptide-2 knockout mice. Cancer Res. 62, 24-27 (2002). (Pubitemid 34073979)
    • (2002) Cancer Research , vol.62 , Issue.1 , pp. 24-27
    • Hayashi, T.1    Faustman, D.L.2
  • 15
    • 33745793005 scopus 로고    scopus 로고
    • The mutation in the ATP-binding region of JAK1, identified in human uterine leiomyosarcomas, results in defective interferon-γ inducibility of TAP1 and LMP2
    • DOI 10.1038/sj.onc.1209434, PII 1209434
    • Hayashi, T., Kobayashi, Y., Kohsaka, S. & Sano, K. The mutation in the ATPbinding region of JAK1, identified in human uterine leiomyosarcomas, results in defective interferon-gamma inducibility of TAP1 and LMP2. Oncogene 25, 4016-4026 (2006). (Pubitemid 44024864)
    • (2006) Oncogene , vol.25 , Issue.29 , pp. 4016-4026
    • Hayashi, T.1    Kobayashi, Y.2    Kohsaka, S.3    Sano, K.4
  • 16
    • 3142769795 scopus 로고    scopus 로고
    • STAT1 regulates lipopolysaccharide- and TNF-α-dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in macrophages by distinct mechanisms
    • Marques, J., Brucet, M., Lloberas, J. & Celada, A. STAT1 regulate lipopolysaccharide-and TNF-a-dependent expression of transporter associated with antigen processing 1 and low molecular mass polypeptide 2 genes in macrophages by distinct mechanisms. J. Immunol. 173, 1103-1110 (2004). (Pubitemid 38924285)
    • (2004) Journal of Immunology , vol.173 , Issue.2 , pp. 1103-1110
    • Marques, L.1    Brucet, M.2    Lloberas, J.3    Celada, A.4
  • 18
    • 53549089344 scopus 로고    scopus 로고
    • CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kB and of NFkB-mediated de novo synthesis of IRF-1
    • Moschonas, A., et al. CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kB and of NFkB-mediated de novo synthesis of IRF-1. Mol. Cell Biol. 28, 6208-6222 (2008).
    • (2008) Mol. Cell Biol , vol.28 , pp. 6208-6222
    • Moschonas, A.1
  • 19
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kB
    • Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S. & Baltimore, D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kB. Nature 376, 167-170 (1995).
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 21
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I-and type-II-interferon-mediated signalling
    • Platanias, L. C. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nature Rev. Immunol. 5, 375-386 (2005).
    • (2005) Nature Rev. Immunol , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 22
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • DOI 10.1038/35077225
    • Blume-Jensen, P. & Hunter, T. Oncogenic kinase signalling. Nature 411, 355-365 (2001). (Pubitemid 32467045)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 25
    • 4944232647 scopus 로고    scopus 로고
    • Lung cancer: Intragenic ERBB2 kinase mutations in tumours
    • Stephens, P., et al. Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature 431, 525-526 (2004).
    • (2004) Nature , vol.431 , pp. 525-526
    • Stephens, P.1
  • 29
    • 34047161940 scopus 로고    scopus 로고
    • JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
    • DOI 10.1016/j.ccr.2007.02.007, PII S1535610807000608
    • Mariani, O., et al. JUN. Oncogene Amplification and Overexpression Block Adipocytic Differentiation in Highly Aggressive Sarcomas. Cancer Cell 11, 361-374 (2007). (Pubitemid 46518313)
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 361-374
    • Mariani, O.1    Brennetot, C.2    Coindre, J.-M.3    Gruel, N.4    Ganem, C.5    Delattre, O.6    Stern, M.-H.7    Aurias, A.8
  • 32
    • 33748171176 scopus 로고    scopus 로고
    • Gene copy number profiling of soft-tissue leiomyosarcomas by array-comparative genomic hybridization
    • DOI 10.1016/j.cancergencyto.2006.01.008, PII S0165460806000537
    • Larramendy, M. L., Kaur, S., Svarvar, C., Böhling, T. & Knuutila, S. Gene copy number profiling of soft-tissue leiomyo-sarcomas by array comparative genome hybridization. Cancer Genet. Cytogen 169, 94-101 (2006). (Pubitemid 44308364)
    • (2006) Cancer Genetics and Cytogenetics , vol.169 , Issue.2 , pp. 94-101
    • Larramendy, M.L.1    Kaur, S.2    Svarvar, C.3    Bohling, T.4    Knuutila, S.5
  • 34
    • 76849102318 scopus 로고    scopus 로고
    • Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling
    • Beck, A. H., et al. Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling. Oncogene 29, 845-854 (2010).
    • (2010) Oncogene , vol.29 , pp. 845-854
    • Beck, A.H.1
  • 39
    • 1542328234 scopus 로고    scopus 로고
    • The IKK/NF-κB activation pathway - A target for prevention and treatment of cancer
    • DOI 10.1016/j.canlet.2003.08.029, PII S0304383503006293
    • Greten, F. R. & Karin, M. The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer. Cancer Lett. 206, 193-199 (2004). (Pubitemid 38317289)
    • (2004) Cancer Letters , vol.206 , Issue.2 , pp. 193-199
    • Greten, F.R.1    Karin, M.2
  • 41
    • 0442323562 scopus 로고    scopus 로고
    • NF-kappaB: Tumor promoter or suppressor?
    • Perkins, N. D. NF-kappaB: tumor promoter or suppressor? Trends Cell Biol. 14, 64-69 (2004).
    • (2004) Trends Cell Biol , vol.14 , pp. 64-69
    • Perkins, N.D.1
  • 42
    • 37049027338 scopus 로고    scopus 로고
    • Nuclear factor-κB, an unappreciated tumor suppressor
    • DOI 10.1158/0008-5472.CAN-07-1576
    • Chen, F. & Castranova, V. Nuclear factor-kappaB, an unappreciated tumor suppressor. Cancer Res. 67, 11093-11098 (2007). (Pubitemid 350248529)
    • (2007) Cancer Research , vol.67 , Issue.23 , pp. 11093-11098
    • Chen, F.1    Castranova, V.2
  • 43
    • 0034681387 scopus 로고    scopus 로고
    • Essential role of human leukocyte antigen-encoded proteasome subunits in NF-κB activation and prevention of tumor necrosis factor-α-induced apoptosis
    • DOI 10.1074/jbc.275.7.5238
    • Hayashi, T. & Faustman, D. Essential role of human leukocyte antigen-encoded proteasome subunits in NF-kB activation and prevention of tumor necrosis factor-alpha-induced apoptosis. J. Biol. Chem. 275, 5238-5247 (2000). (Pubitemid 30108929)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.7 , pp. 5238-5247
    • Hayashi, T.1    Faustman, D.2
  • 44
    • 31944432777 scopus 로고    scopus 로고
    • Proteasome subunit LMP2 is required for matrix metalloproteinase-2 and-9 expression and activities in human invasive extravillous trophoblast cell line
    • Wang, H. X., et al. Proteasome subunit LMP2 is required for matrix metalloproteinase-2 and-9 expression and activities in human invasive extravillous trophoblast cell line. J. Cell Physiol. 206, 616-623 (2006).
    • (2006) J. Cell Physiol , vol.206 , pp. 616-623
    • Wang, H.X.1
  • 47
    • 33745190319 scopus 로고    scopus 로고
    • Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients
    • Ylisaukko-oja, S. K., et al. Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients. Int. J. Cancer 119, 283-287 (2006).
    • (2006) Int. J. Cancer , vol.119 , pp. 283-287
    • Ylisaukko-Oja, S.K.1
  • 48
    • 70349659679 scopus 로고    scopus 로고
    • Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyomalike areas
    • Mittal, K. R., et al. Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyomalike areas. Mod. Pathol. 10, 1303-1311 (2009).
    • (2009) Mod. Pathol , vol.10 , pp. 1303-1311
    • Mittal, K.R.1
  • 49
    • 0027320946 scopus 로고
    • The major-histocompatibility-complex-encoded β-type proteasome subunits LMP2 and LMP7. Evidence that LMP2 and LMP7 are synthesized as proteins and that cellular levels of both mRNA and LMP-containing 20S proteasomes are differentially regulated
    • Frentzel, S., et al. The major histocompatibility complex encoded beta-type proteasome subunits LMP2 and LMP7. Evidence that LMP2 and LMP7 are synthesized as proproteins and that cellular levels of both mRNA and LMPcontaining 20S proteasomes are differentially regulated. Eur. J. Biochem. 216, 119-26 (1993). (Pubitemid 23255178)
    • (1993) European Journal of Biochemistry , vol.216 , Issue.1 , pp. 119-126
    • Frentzel, S.1    Kuhn-Hartmann, I.2    Gernold, M.3    Gott, P.4    Seelig, A.5    Kloetzel, P.-M.6
  • 50
    • 0029870267 scopus 로고    scopus 로고
    • A component of the 26S proteasome binds an orphan member of the nuclear hormone receptor superfamily
    • DOI 10.1016/0960-0760(95)00220-0
    • Choi, H. S., Seol, W. & Moore, D. D. A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily. J. Steroid Biochem. Biol. 56, 23-30 (1996). (Pubitemid 26106507)
    • (1996) Journal of Steroid Biochemistry and Molecular Biology , vol.56 , Issue.1-6 , pp. 23-30
    • Choi, H.-S.1    Seol, W.2    Moore, D.D.3
  • 51
    • 33748947865 scopus 로고    scopus 로고
    • The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription
    • DOI 10.1038/sj.emboj.7601306, PII 7601306
    • Zhang, H., et al. The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription. EMBO J. 25, 4223-33 (2006). (Pubitemid 44435220)
    • (2006) EMBO Journal , vol.25 , Issue.18 , pp. 4223-4233
    • Zhang, H.1    Sun, L.2    Liang, J.3    Yu, W.4    Zhang, Y.5    Wang, Y.6    Chen, Y.7    Li, R.8    Sun, X.9    Shang, Y.10
  • 52
    • 0030703686 scopus 로고    scopus 로고
    • Dynamics of proteasome distribution in living cells
    • DOI 10.1093/emboj/16.20.6087
    • Reits, E. A., Benham, A. M., Plougastel, B., Neefies, J. & Trowsdale, J. Dynamics of proteasome distribution in living cells. EMBO J. 16, 6087-94 (1997). (Pubitemid 27458328)
    • (1997) EMBO Journal , vol.16 , Issue.20 , pp. 6087-6094
    • Reits, E.A.J.1    Benham, A.M.2    Plougastel, B.3    Neefjes, J.4    Trowsdale, J.5
  • 54
    • 33847260150 scopus 로고    scopus 로고
    • Tyrosine kinase mutations in human cancer
    • DOI 10.2174/156652407779940486
    • Lengyel, E., Sawada, K. & Salgia, R. Tyrosine kinase mutations in human cancer. Curr. Mol. Med. 7, 77-84 (2007). (Pubitemid 46322280)
    • (2007) Current Molecular Medicine , vol.7 , Issue.1 , pp. 77-84
    • Lengyel, E.1    Sawada, K.2    Salgia, R.3
  • 55
    • 33947541694 scopus 로고    scopus 로고
    • Alternative splicing: An emerging topic in molecular and clinical oncology
    • DOI 10.1016/S1470-2045(07)70104-3, PII S1470204507701043
    • Pajares, M. J., et al. Alternative splicing: an emerging topic in molecular and clinical oncology. Lancet Oncol. 8, 349-357 (2007). (Pubitemid 46464532)
    • (2007) Lancet Oncology , vol.8 , Issue.4 , pp. 349-357
    • Pajares, M.J.1    Ezponda, T.2    Catena, R.3    Calvo, A.4    Pio, R.5    Montuenga, L.M.6
  • 57
    • 34047161940 scopus 로고    scopus 로고
    • JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
    • DOI 10.1016/j.ccr.2007.02.007, PII S1535610807000608
    • Mariani, O., et al. JUN. Oncogene Amplifi cation and Overexpression Block Adipocytic Differentiation in Highly Aggressive Sarcomas. Cancer Cell 11, 361-374 (2007). (Pubitemid 46518313)
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 361-374
    • Mariani, O.1    Brennetot, C.2    Coindre, J.-M.3    Gruel, N.4    Ganem, C.5    Delattre, O.6    Stern, M.-H.7    Aurias, A.8
  • 58
    • 77955090106 scopus 로고    scopus 로고
    • Subtype-specific genomic alterations define new targets for softtissue sarcoma therapy
    • Barretina, J., et al. Subtype-specific genomic alterations define new targets for softtissue sarcoma therapy. Nature Genet. 8, 715-721 (2010).
    • (2010) Nature Genet , vol.8 , pp. 715-721
    • Barretina, J.1
  • 59
    • 77954535843 scopus 로고    scopus 로고
    • Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
    • Chibon, F., et al. Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity. Nature Med. 16, 781-787 (2010).
    • (2010) Nature Med , vol.16 , pp. 781-787
    • Chibon, F.1
  • 60
    • 33745192054 scopus 로고    scopus 로고
    • The nuclear ubiquitin-proteasome system
    • Mikecz, A. V. The nuclear ubiquitin-proteasome system. J. Cell Science 119, 1977-1984 (2006).
    • (2006) J. Cell Science , vol.119 , pp. 1977-1984
    • Mikecz, A.V.1
  • 61
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • Swann, J. B. & Smyth, M. J. Immune surveillance of tumors. J. Clin. Inve. 117, 1137-1196 (2007).
    • (2007) J. Clin. Inve , vol.117 , pp. 1137-1196
    • Swann, J.B.1    Smyth, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.