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Volumn 109, Issue 1, 2014, Pages 73-82

Neuroendocrinology of obesity

Author keywords

gut hormone; obesity; therapy

Indexed keywords

AMYLIN; CHOLECYSTOKININ; GASTRIC INHIBITORY POLYPEPTIDE; GASTROINTESTINAL HORMONE; GHRELIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; INSULIN; LEPTIN; OXYNTOMODULIN; PANCREAS POLYPEPTIDE; PEPTIDE YY; PEPTIDE YY [3-36]; PRAMLINTIDE;

EID: 84895898289     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldu001     Document Type: Article
Times cited : (12)

References (43)
  • 2
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • Morton GJ, Cummings DE, Baskin DG, et al. Central nervous system control of food intake and body weight. Nature 2006;443:289-95.
    • (2006) Nature , vol.443 , pp. 289-295
    • Morton, G.J.1    Cummings, D.E.2    Baskin, D.G.3
  • 3
    • 70449255388 scopus 로고
    • The effects of lesions in the hypothalamus in parabiotic rats
    • Hervey GR. The effects of lesions in the hypothalamus in parabiotic rats. J Physiol 1959;145:336-52.
    • (1959) J Physiol , vol.145 , pp. 336-352
    • Hervey, G.R.1
  • 4
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978;14:141-8.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 5
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3
  • 6
    • 0029073613 scopus 로고
    • Weightreducing effects of the plasma protein encoded by the obese gene
    • Halaas JL, Gajiwala KS, Maffei M, et al. Weightreducing effects of the plasma protein encoded by the obese gene. Science 1995;269:543-6.
    • (1995) Science , vol.269 , pp. 543-546
    • Halaas, J.L.1    Gajiwala, K.S.2    Maffei, M.3
  • 7
    • 0033575993 scopus 로고    scopus 로고
    • Effects of recombinant leptin therapy in a child with congenital leptin deficiency
    • Farooqi IS, Jebb SA, Langmack G, et al. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 1999;341:879-84.
    • (1999) N Engl J Med , vol.341 , pp. 879-884
    • Farooqi, I.S.1    Jebb, S.A.2    Langmack, G.3
  • 8
    • 0037847510 scopus 로고    scopus 로고
    • Characterization of the effects of pancreatic polypeptide in the regulation of energy balance
    • Asakawa A, Inui A, Yuzuriha H, et al. Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Gastroenterology 2003;124:1325-36.
    • (2003) Gastroenterology , vol.124 , pp. 1325-1336
    • Asakawa, A.1    Inui, A.2    Yuzuriha, H.3
  • 9
    • 0027190603 scopus 로고
    • Pancreatic polypeptide infusions reduce food intake in Prader-Willi syndrome
    • Berntson GG, Zipf WB, O'Dorisio TM, et al. Pancreatic polypeptide infusions reduce food intake in Prader-Willi syndrome. Peptides 1993;14:497-503.
    • (1993) Peptides , vol.14 , pp. 497-503
    • Berntson, G.G.1    Zipf, W.B.2    O'Dorisio, T.M.3
  • 10
    • 0041882174 scopus 로고    scopus 로고
    • Pancreatic polypeptide reduces appetite and food intake in humans
    • Batterham RL, le Roux CW, Cohen MA, et al. Pancreatic polypeptide reduces appetite and food intake in humans. J Clin Endocrinol Metab 2003;88:3989-92.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3989-3992
    • Batterham, R.L.1    Le Roux, C.W.2    Cohen, M.A.3
  • 11
    • 84855505560 scopus 로고    scopus 로고
    • Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420
    • Tan TM, Field BCT, Minnion JS, et al. Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420. Br J Clin Pharmacol 2012;73:232-9.
    • (2012) Br J Clin Pharmacol , vol.73 , pp. 232-239
    • Tan, T.M.1    Field, B.C.T.2    Minnion, J.S.3
  • 12
    • 33747763918 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes
    • Edelman S, Garg S, Frias J, et al. A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes. Diabetes Care 2006;29:2189-95.
    • (2006) Diabetes Care , vol.29 , pp. 2189-2195
    • Edelman, S.1    Garg, S.2    Frias, J.3
  • 13
    • 69749086148 scopus 로고    scopus 로고
    • Enhanced weight loss with pramlintide/metreleptin: An integrated neurohormonal approach to obesity pharmacotherapy
    • Ravussin E, Smith SR, Mitchell JA, et al. Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy. Obesity 2009;17:1736-43.
    • (2009) Obesity , vol.17 , pp. 1736-1743
    • Ravussin, E.1    Smith, S.R.2    Mitchell, J.A.3
  • 14
    • 0016215903 scopus 로고
    • Glucagon control of fasting glucose in man
    • Alford FP, Bloom SR, Nabarro JDN, et al. Glucagon control of fasting glucose in man. Lancet 1974;304: 974-7.
    • (1974) Lancet , vol.304 , pp. 974-977
    • Alford, F.P.1    Bloom, S.R.2    Nabarro, J.D.N.3
  • 15
    • 0001300387 scopus 로고
    • Effect of glucagon on food intake and body weight in man
    • Schulman JL, Carleton JL, Whitney G, et al. Effect of glucagon on food intake and body weight in man. J Appl Physiol 1957;11:419-21.
    • (1957) J Appl Physiol , vol.11 , pp. 419-421
    • Schulman, J.L.1    Carleton, J.L.2    Whitney, G.3
  • 16
    • 77956313886 scopus 로고    scopus 로고
    • Gcg-XTEN: An improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose
    • Geething NC, To W, Spink BJ, et al. Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose. PLoS ONE 2010;5:e10175.
    • (2010) PLoS ONE , vol.5
    • Geething, N.C.1    To, W.2    Spink, B.J.3
  • 17
    • 2942558193 scopus 로고    scopus 로고
    • Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time-and food-related cues
    • Cummings DE, Frayo RS, Marmonier C, et al. Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time-and food-related cues. Am J Physiol Endocrinol Metab 2004;287: E297-304.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Cummings, D.E.1    Frayo, R.S.2    Marmonier, C.3
  • 18
    • 0035216623 scopus 로고    scopus 로고
    • Ghrelin enhances appetite and increases food intake in humans
    • Wren AM, Seal LJ, Cohen MA, et al. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 2001;86:5992-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5992-5995
    • Wren, A.M.1    Seal, L.J.2    Cohen, M.A.3
  • 19
    • 55749097801 scopus 로고    scopus 로고
    • Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: A randomized trial
    • Nass R, Pezzoli SS, Oliveri MC, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med 2008;149:601-11.
    • (2008) Ann Intern Med , vol.149 , pp. 601-611
    • Nass, R.1    Pezzoli, S.S.2    Oliveri, M.C.3
  • 20
    • 4444260060 scopus 로고    scopus 로고
    • Inhibition of ghrelin action in vitro and in vivo by an RNA-Spiegelmer
    • Helmling S, Maasch C, Eulberg D, et al. Inhibition of ghrelin action in vitro and in vivo by an RNA-Spiegelmer. ProcNatl Acad Sci USA 2004;101:13174-9.
    • (2004) ProcNatl Acad Sci USA , vol.101 , pp. 13174-13179
    • Helmling, S.1    Maasch, C.2    Eulberg, D.3
  • 21
    • 32644448802 scopus 로고    scopus 로고
    • Ghrelin neutralization by a ribonucleic acid-SPM ameliorates obesity in diet-induced obese mice
    • Shearman LP, Wang S-P, Helmling S, et al. Ghrelin neutralization by a ribonucleic acid-SPM ameliorates obesity in diet-induced obese mice. Endocrinology 2006;147: 1517-26.
    • (2006) Endocrinology , vol.147 , pp. 1517-1526
    • Shearman, L.P.1    Wang, S.-P.2    Helmling, S.3
  • 22
    • 0021433344 scopus 로고
    • Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats
    • West DB, Fey D,Woods SC. Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats. Am J Physiol Regul Integr Comp Physiol 1984;246: R776-87.
    • (1984) Am J Physiol Regul Integr Comp Physiol , vol.246
    • West, D.B.1    Fey Dwoods, S.C.2
  • 23
    • 38349104637 scopus 로고    scopus 로고
    • Stimulation of cholecystokinin-A receptors with GI181771X does not cause weight loss in overweight or obese patients
    • Jordan J, Greenway FL, Leiter LA, et al. Stimulation of cholecystokinin-A receptors with GI181771X does not cause weight loss in overweight or obese patients. Clin Pharmacol Ther 2008;83:281-7.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 281-287
    • Jordan, J.1    Greenway, F.L.2    Leiter, L.A.3
  • 24
    • 0023638829 scopus 로고
    • Glucagonlike peptide-1 7-36: A physiological incretin in man
    • Kreymann B, Williams G, Ghatei MA, et al. Glucagonlike peptide-1 7-36: a physiological incretin in man. Lancet 1987;330:1300-4.
    • (1987) Lancet , vol.330 , pp. 1300-1304
    • Kreymann, B.1    Williams, G.2    Ghatei, M.A.3
  • 25
    • 0027391607 scopus 로고
    • Preserved incretin activity of glucagon-like peptide 1[7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
    • Nauck MA, Heimesaat MM, Ørskov C, et al. Preserved incretin activity of glucagon-like peptide 1[7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993;91:301-7.
    • (1993) J Clin Invest , vol.91 , pp. 301-307
    • Nauck, M.A.1    Heimesaat, M.M.2    Oslashrskov, C.3
  • 26
    • 13344282056 scopus 로고    scopus 로고
    • A role for glucagon-like peptide-1 in the central regulation of feeding
    • Turton MD, O'Shea D, Gunn I, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996;379:69-72.
    • (1996) Nature , vol.379 , pp. 69-72
    • Turton, M.D.1    O'Shea, D.2    Gunn, I.3
  • 27
    • 0037045845 scopus 로고    scopus 로고
    • Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: A parallel-group study
    • ZanderM,Madsbad S,Madsen JL, et al. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study. Lancet 2002;359:824-30.
    • (2002) Lancet , vol.359 , pp. 824-830
    • Zander, M.1    Madsbad, S.2    Madsen, J.L.3
  • 28
    • 84866125785 scopus 로고    scopus 로고
    • Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers
    • Adrian TE, Gariballa S, Parekh KA, et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia 2012;55:2343-7.
    • (2012) Diabetologia , vol.55 , pp. 2343-2347
    • Adrian, T.E.1    Gariballa, S.2    Parekh, K.A.3
  • 29
    • 84880611045 scopus 로고    scopus 로고
    • Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists
    • Dehmlow H, Alvarez Sánchez R, Bachmann S, et al. Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists. Bioorg Med Chem Lett 2013;23: 4627-32.
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 4627-4632
    • Dehmlow, H.1    Alvarez Sánchez, R.2    Bachmann, S.3
  • 30
    • 35649021752 scopus 로고    scopus 로고
    • Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass
    • le Roux CW, Welbourn R, Werling M, et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg 2007;246:780-5.
    • (2007) Ann Surg , vol.246 , pp. 780-785
    • Le Roux, C.W.1    Welbourn, R.2    Werling, M.3
  • 31
    • 33745841347 scopus 로고    scopus 로고
    • The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR
    • Nygaard R, Nielbo S, Schwartz TW, et al. The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR. Biochemistry 2006;45:8350-7.
    • (2006) Biochemistry , vol.45 , pp. 8350-8357
    • Nygaard, R.1    Nielbo, S.2    Schwartz, T.W.3
  • 32
    • 0041859261 scopus 로고    scopus 로고
    • Inhibition of food intake in obese subjects by peptide YY3-36
    • Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003;349:941-8.
    • (2003) N Engl J Med , vol.349 , pp. 941-948
    • Batterham, R.L.1    Cohen, M.A.2    Ellis, S.M.3
  • 33
    • 34249862701 scopus 로고    scopus 로고
    • Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults
    • Gantz I, Erondu N, Mallick M, et al. Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults. J Clin Endocrinol Metab 2007;92:1754-7.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1754-1757
    • Gantz, I.1    Erondu, N.2    Mallick, M.3
  • 34
    • 27844508598 scopus 로고    scopus 로고
    • Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively
    • Neary NM, Small CJ, Druce MR, et al. Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively. Endocrinology 2005;146:5120-7.
    • (2005) Endocrinology , vol.146 , pp. 5120-5127
    • Neary, N.M.1    Small, C.J.2    Druce, M.R.3
  • 35
    • 77954252801 scopus 로고    scopus 로고
    • PYY3x36 and oxyntomodulin can be additive in their effect on food intake in overweight and obese humans
    • Field BCT, Wren AM, Peters V, et al. PYY3x36 and oxyntomodulin can be additive in their effect on food intake in overweight and obese humans. Diabetes 2010;59: 1635-9.
    • (2010) Diabetes , vol.59 , pp. 1635-1639
    • Field, B.C.T.1    Wren, A.M.2    Peters, V.3
  • 36
    • 0019527355 scopus 로고
    • 'Enteroglucagon': A specific effect on gastric glands isolated from the rat fundus Evidence for an 'oxyntomodulin' action
    • Bataille D, Gespach C, Coudray AM, et al. 'Enteroglucagon': a specific effect on gastric glands isolated from the rat fundus. Evidence for an 'oxyntomodulin' action. Biosci Rep 1981;1:151-5.
    • (1981) Biosci Rep , vol.1 , pp. 151-155
    • Bataille, D.1    Gespach, C.2    Coudray, A.M.3
  • 37
    • 23644443678 scopus 로고    scopus 로고
    • Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: A double-blind, randomized, controlled trial
    • Wynne K, Park AJ, Small CJ, et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes 2005;54:2390-5.
    • (2005) Diabetes , vol.54 , pp. 2390-2395
    • Wynne, K.1    Park, A.J.2    Small, C.J.3
  • 38
    • 0242288734 scopus 로고    scopus 로고
    • Oxyntomodulin suppresses appetite and reduces food intake in humans
    • Cohen MA, Ellis SM, le Roux CW, et al. Oxyntomodulin suppresses appetite and reduces food intake in humans. J Clin Endocrinol Metab 2003;88:4696-701.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4696-4701
    • Cohen, M.A.1    Ellis, S.M.2    Le Roux, C.W.3
  • 39
    • 33749339257 scopus 로고    scopus 로고
    • Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial
    • Wynne K, Park AJ, Small CJ, et al. Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial. Int J Obes 2006;30:1729-36.
    • (2006) Int J Obes , vol.30 , pp. 1729-1736
    • Wynne, K.1    Park, A.J.2    Small, C.J.3
  • 40
    • 84875409178 scopus 로고    scopus 로고
    • Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia
    • Tan TM, Field BCT, McCullough KA, et al. Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia. Diabetes 2013;62:1131-8.
    • (2013) Diabetes , vol.62 , pp. 1131-1138
    • Tan, T.M.1    Field, B.C.T.2    McCullough, K.A.3
  • 41
    • 70349644658 scopus 로고    scopus 로고
    • Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice
    • Pocai A, Carrington PE, Adams JR, et al. Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes 2009;58:2258-66.
    • (2009) Diabetes , vol.58 , pp. 2258-2266
    • Pocai, A.1    Carrington, P.E.2    Adams, J.R.3
  • 42
    • 70349308687 scopus 로고    scopus 로고
    • A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
    • Day JW, Ottaway N, Patterson JT, et al. A new glucagon and GLP-1 co-agonist eliminates obesity in rodents. Nat Chem Biol 2009;5:749-57.
    • (2009) Nat Chem Biol , vol.5 , pp. 749-757
    • Day, J.W.1    Ottaway, N.2    Patterson, J.T.3
  • 43
    • 84891375601 scopus 로고    scopus 로고
    • Activity of pramlintide, rat and human amylin but not Aβ1-42 at human amylin receptors
    • Gingell JJ, Burns ER, Hay DL. Activity of pramlintide, rat and human amylin but not Aβ1-42 at human amylin receptors. Endocrinology 2014;155:21-6.
    • (2014) Endocrinology , vol.155 , pp. 21-26
    • Gingell, J.J.1    Burns, E.R.2    Hay, D.L.3


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