메뉴 건너뛰기




Volumn 62, Issue 4, 2013, Pages 1131-1138

Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN;

EID: 84875409178     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0797     Document Type: Article
Times cited : (195)

References (39)
  • 1
    • 84857401843 scopus 로고    scopus 로고
    • Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes
    • Cryer PE. Minireview: glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes. Endocrinology 2012;153:1039-1048
    • (2012) Endocrinology , vol.153 , pp. 1039-1048
    • Cryer, P.E.1
  • 2
    • 84857408980 scopus 로고    scopus 로고
    • Minireview: Glucagon in stress and energy homeostasis
    • Jones BJ, Tan T, Bloom SR. Minireview: glucagon in stress and energy homeostasis. Endocrinology 2012;153:1049-1054
    • (2012) Endocrinology , vol.153 , pp. 1049-1054
    • Jones, B.J.1    Tan, T.2    Bloom, S.R.3
  • 3
    • 33845998516 scopus 로고    scopus 로고
    • The role of gut hormones in glucose homeostasis
    • Drucker DJ. The role of gut hormones in glucose homeostasis. J Clin Invest 2007;117:24-32
    • (2007) J Clin Invest , vol.117 , pp. 24-32
    • Drucker, D.J.1
  • 4
    • 0019766354 scopus 로고
    • Bioactive enteroglucagon (oxyntomodulin): Present knowledge on its chemical structure and its biological activities
    • Bataille D, Gespach C, Tatemoto K, et al. Bioactive enteroglucagon (oxyntomodulin): present knowledge on its chemical structure and its biological activities. Peptides 1981;2(Suppl. 2):41-44
    • (1981) Peptides , vol.2 , Issue.SUPPL. 2 , pp. 41-44
    • Bataille, D.1    Gespach, C.2    Tatemoto, K.3
  • 5
    • 0034807498 scopus 로고    scopus 로고
    • Oxyntomodulin inhibits food intake in the rat
    • Dakin CL, Gunn I, Small CJ, et al. Oxyntomodulin inhibits food intake in the rat. Endocrinology 2001;142:4244-4250
    • (2001) Endocrinology , vol.142 , pp. 4244-4250
    • Dakin, C.L.1    Gunn, I.2    Small, C.J.3
  • 6
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998;101:515-520
    • (1998) J Clin Invest , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 7
    • 70350619609 scopus 로고    scopus 로고
    • Effects of liraglutide in the treatment of obesity: A randomised double-blind placebo-controlled study
    • NN8022-1807 Study Group
    • Astrup A, Rössner S, Van Gaal L, et al.; NN8022-1807 Study Group. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009;374:1606-1616
    • (2009) Lancet , vol.374 , pp. 1606-1616
    • Astrup, A.1    Rössner, S.2    Van Gaal, L.3
  • 8
    • 0034011021 scopus 로고    scopus 로고
    • The effect of glucagonlike peptide-1 on energy expenditure and substrate metabolism in humans
    • Flint A, Raben A, Rehfeld JF, Holst JJ, Astrup A. The effect of glucagonlike peptide-1 on energy expenditure and substrate metabolism in humans. Int J Obes Relat Metab Disord 2000;24:288-298
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 288-298
    • Flint, A.1    Raben, A.2    Rehfeld, J.F.3    Holst, J.J.4    Astrup, A.5
  • 10
    • 0023225708 scopus 로고
    • Hyperglucagonemia increases resting metabolic rate in man during insulin deficiency
    • Nair KS. Hyperglucagonemia increases resting metabolic rate in man during insulin deficiency. J Clin Endocrinol Metab 1987;64:896-901
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 896-901
    • Nair, K.S.1
  • 11
    • 0242288734 scopus 로고    scopus 로고
    • Oxyntomodulin suppresses appetite and reduces food intake in humans
    • Cohen MA, Ellis SM, Le Roux CW, et al. Oxyntomodulin suppresses appetite and reduces food intake in humans. J Clin Endocrinol Metab 2003; 88:4696-4701
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4696-4701
    • Cohen, M.A.1    Ellis, S.M.2    Le Roux, C.W.3
  • 12
    • 33749339257 scopus 로고    scopus 로고
    • Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: A randomised controlled trial
    • Wynne K, Park AJ, Small CJ, et al. Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial. Int J Obes (Lond) 2006;30:1729-1736
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1729-1736
    • Wynne, K.1    Park, A.J.2    Small, C.J.3
  • 13
    • 23644443678 scopus 로고    scopus 로고
    • Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: A double-blind, randomized, controlled trial
    • Wynne K, Park AJ, Small CJ, et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes 2005;54:2390-2395
    • (2005) Diabetes , vol.54 , pp. 2390-2395
    • Wynne, K.1    Park, A.J.2    Small, C.J.3
  • 14
    • 54349119151 scopus 로고    scopus 로고
    • The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice
    • Maida A, Lovshin JA, Baggio LL, Drucker DJ. The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice. Endocrinology 2008;149:5670-5678
    • (2008) Endocrinology , vol.149 , pp. 5670-5678
    • Maida, A.1    Lovshin, J.A.2    Baggio, L.L.3    Drucker, D.J.4
  • 15
    • 70349308687 scopus 로고    scopus 로고
    • A new glucagon and GLP-1 coagonist eliminates obesity in rodents
    • Day JW, Ottaway N, Patterson JT, et al. A new glucagon and GLP-1 coagonist eliminates obesity in rodents. Nat Chem Biol 2009;5:749-757
    • (2009) Nat Chem Biol , vol.5 , pp. 749-757
    • Day, J.W.1    Ottaway, N.2    Patterson, J.T.3
  • 16
    • 70349644658 scopus 로고    scopus 로고
    • Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice
    • Pocai A, Carrington PE, Adams JR, et al. Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes 2009;58:2258-2266
    • (2009) Diabetes , vol.58 , pp. 2258-2266
    • Pocai, A.1    Carrington, P.E.2    Adams, J.R.3
  • 17
    • 0035192716 scopus 로고    scopus 로고
    • Short-term effects of a progestational contraceptive drug on food intake, resting energy expenditure, and body weight in young women
    • Pelkman CL, Chow M, Heinbach RA, Rolls BJ. Short-term effects of a progestational contraceptive drug on food intake, resting energy expenditure, and body weight in young women. Am J Clin Nutr 2001;73:19-26
    • (2001) Am J Clin Nutr , vol.73 , pp. 19-26
    • Pelkman, C.L.1    Chow, M.2    Heinbach, R.A.3    Rolls, B.J.4
  • 18
    • 8944256349 scopus 로고
    • New methods for calculating metabolic rate with special reference to protein metabolism
    • Weir JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949;109:1-9
    • (1949) J Physiol , vol.109 , pp. 1-9
    • Weir, J.B.1
  • 19
    • 0020576146 scopus 로고
    • Calculation of substrate oxidation rates in vivo from gaseous exchange
    • Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983;55:628-634
    • (1983) J Appl Physiol , vol.55 , pp. 628-634
    • Frayn, K.N.1
  • 20
    • 0016802564 scopus 로고
    • Carrier solutions for low-level intravenous insulin infusion
    • Kraegen EW, Lazarus L, Meler H, Campbell L, Chia YO. Carrier solutions for low-level intravenous insulin infusion. BMJ 1975;3:464-466
    • (1975) BMJ , vol.3 , pp. 464-466
    • Kraegen, E.W.1    Lazarus, L.2    Meler, H.3    Campbell, L.4    Chia, Y.O.5
  • 21
    • 0023638829 scopus 로고
    • Glucagon-like peptide-1 7-36: A physiological incretin in man
    • Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 1987;2:1300-1304
    • (1987) Lancet , Issue.2 , pp. 1300-1304
    • Kreymann, B.1    Williams, G.2    Ghatei, M.A.3    Bloom, S.R.4
  • 23
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren AM, Small CJ, Ward HL, et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000;141:4325-4328
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3
  • 24
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999;402:656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 25
    • 0026653715 scopus 로고
    • Individual, but not simultaneous, glucagon and cholecystokinin infusions inhibit feeding in men
    • Geary N, Kissileff HR, Pi-Sunyer FX, Hinton V. Individual, but not simultaneous, glucagon and cholecystokinin infusions inhibit feeding in men. Am J Physiol 1992;262:R975-R980
    • (1992) Am J Physiol , vol.262
    • Geary, N.1    Kissileff, H.R.2    Pi-Sunyer, F.X.3    Hinton, V.4
  • 26
    • 26244438874 scopus 로고    scopus 로고
    • Glucagon inhibits ghrelin secretion in humans
    • Arafat MA, Otto B, Rochlitz H, et al. Glucagon inhibits ghrelin secretion in humans. Eur J Endocrinol 2005;153:397-402
    • (2005) Eur J Endocrinol , vol.153 , pp. 397-402
    • Arafat, M.A.1    Otto, B.2    Rochlitz, H.3
  • 27
    • 34547650656 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
    • Hagemann D, Holst JJ, Gethmann A, Banasch M, Schmidt WE, Meier JJ. Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion. Regul Pept 2007;143:64-68
    • (2007) Regul Pept , vol.143 , pp. 64-68
    • Hagemann, D.1    Holst, J.J.2    Gethmann, A.3    Banasch, M.4    Schmidt, W.E.5    Meier, J.J.6
  • 28
    • 0026077868 scopus 로고
    • Glucagon in physiological concentrations stimulates brown fat thermogenesis in vivo
    • Billington CJ, Briggs JE, Link JG, Levine AS. Glucagon in physiological concentrations stimulates brown fat thermogenesis in vivo. Am J Physiol 1991;261:R501-R507
    • (1991) Am J Physiol , vol.261
    • Billington, C.J.1    Briggs, J.E.2    Link, J.G.3    Levine, A.S.4
  • 30
    • 64749101898 scopus 로고    scopus 로고
    • Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes
    • Ali S, Drucker DJ. Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes. Am J Physiol Endocrinol Metab 2009;296: E415-E421
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Ali, S.1    Drucker, D.J.2
  • 31
    • 79959781838 scopus 로고    scopus 로고
    • Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes
    • Holst JJ, Knop FK, Vilsbøll T, Krarup T, Madsbad S. Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes. Diabetes Care 2011;34(Suppl. 2):S251-S257
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 2
    • Holst, J.J.1    Knop, F.K.2    Vilsbøll, T.3    Krarup, T.4    Madsbad, S.5
  • 32
    • 79959803070 scopus 로고    scopus 로고
    • Incretin effects on b-cell function, replication, and mass: The human perspective
    • Garber AJ. Incretin effects on b-cell function, replication, and mass: the human perspective. Diabetes Care 2011;34(Suppl 2):S258-S263
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 2
    • Garber, A.J.1
  • 33
    • 0035044628 scopus 로고    scopus 로고
    • Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo
    • Bertin E, Arner P, Bolinder J, Hagström-Toft E. Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo. J Clin Endocrinol Metab 2001; 86:1229-1234
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1229-1234
    • Bertin, E.1    Arner, P.2    Bolinder, J.3    Hagström-Toft, E.4
  • 34
    • 0013977135 scopus 로고
    • Interrelationship of glucagon, insulin and glucose. The insulinogenic effect of glucagon
    • Samols E, Marri G, Marks V. Interrelationship of glucagon, insulin and glucose. The insulinogenic effect of glucagon. Diabetes 1966;15: 855-866
    • (1966) Diabetes , vol.15 , pp. 855-866
    • Samols, E.1    Marri, G.2    Marks, V.3
  • 36
    • 33748756611 scopus 로고    scopus 로고
    • Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level
    • Arafat AM, Perschel FH, Otto B, et al. Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level. J Clin Endocrinol Metab 2006;91:3528-3533
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3528-3533
    • Arafat, A.M.1    Perschel, F.H.2    Otto, B.3
  • 39
    • 1042298109 scopus 로고    scopus 로고
    • Partitioning variation in multilevel models
    • Goldstein H, Browne W, Rasbash J. Partitioning variation in multilevel models. Underst Stat 2002;1:223-231
    • (2002) Underst Stat , vol.1 , pp. 223-231
    • Goldstein, H.1    Browne, W.2    Rasbash, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.