Defining the interactions and role of DCAF1/VPRBP in the DDB1-Cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Gérard, Francine C A ^a   Yang, Ruifeng ^a   Romani, Bizhan ^a   Poisson, Alexis ^a   Belzile, Jean Philippe ^a   Rougeau, Nicole ^a   Cohen, Éric A ^a,b  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CULLIN4A PROTEIN; DCAF1 PROTEIN; DDB1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS PROTEIN; VPR PROTEIN;

ARTICLE; CELL ACTIVITY; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL FRACTIONATION; CELL LYSATE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; F BOX MOTIF; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CARRIER PROTEINS; CULLIN PROTEINS; DNA-BINDING PROTEINS; G2 PHASE CELL CYCLE CHECKPOINTS; HEK293 CELLS; HELA CELLS; HIV INFECTIONS; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PLASMIDS; PROTEIN BINDING; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; VPR GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84895894420     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089195     Document Type: Article

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