Inhibitor of nuclear factor-κB, SN50, attenuates lipopolysaccharide- induced lung injury in an isolated and perfused rat lung model

Translational Research

Volumn 163, Issue 3, 2014, Pages 211-220

  Chian, Chih Feng ^a   Chiang, Chi Huei ^a,b,c   Chuang, Chiao Hui ^b   Liu, Shiou Ling ^b  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; SN 50; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HISTOPATHOLOGY; INFLAMMATION; LUNG BLOOD VESSEL; LUNG HEMODYNAMICS; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; LUNG PERFUSION; LUNG WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WEIGHT CHANGE; WEIGHT GAIN;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; LUNG INJURY; MALE; NF-KAPPA B; ORGAN SIZE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84895891831     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2013.10.002     Document Type: Article

References (36)

1. A. Melamed, and F.J. Sorvillo The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data Crit Care 13 2009 R28
2. G.D. Rubenfeld, E. Caldwell, and E. Peabody et al. Incidence and outcomes of acute lung injury N Engl J Med 353 2005 1685 1693
3. M.A. Matthay, L.B. Ware, and G.A. Zimmerman The acute respiratory distress syndrome J Clin Invest 122 2012 2731 2740
4. S. Akira, and K. Takeda Toll-like receptor signalling Nat Rev Immunol 4 2004 499 511
5. A.A. Komissarov, D. Stankowska, and A. Krupa et al. Novel aspects of urokinase function in the injured lung: role of α2-macroglobulin Am J Physiol Lung Cell Mol Physiol 303 2012 L1037 L1045
6. S. Ghosh, and M.S. Hayden Celebrating 25 years of NF-κB research Immunol Rev 246 2012 5 13
7. P. Rao, M.S. Hayden, and M. Long et al. IκBbeta acts to inhibit and activate gene expression during the inflammatory response Nature 466 2010 1115 1119
8. S.F. Liu, and A.B. Malik NF-κB activation as a pathological mechanism of septic shock and inflammation Am J Physiol Lung Cell Mol Physiol 290 2006 L622 L645
9. J.S. Mattick, Q. Yang, M.A. Orman, M.G. Ierapetritou, F. Berthiaume, and I.P. Androulakis Long-term gene expression profile dynamics following cecal ligation and puncture in the rat J Surg Res 178 2012 431 442
10. P.A. Ganchi, S.C. Sun, W.C. Greene, and D.W. Ballard I κB/MAD-3 masks the nuclear localization signal of NF-κB p65 and requires the transactivation domain to inhibit NF-κB p65 DNA binding Mol Biol Cell 3 1992 1339 1352
11. A.A. Beg, S.M. Ruben, R.I. Scheinman, S. Haskill, C.A. Rosen, and A.S. Baldwin Jr. I κB interacts with the nuclear localization sequences of the subunits of NF-κB: a mechanism for cytoplasmic retention Genes Dev 6 1992 1899 1913
12. Y.Z. Lin, S.Y. Yao, R.A. Veach, T.R. Torgerson, and J. Hawiger Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence J Biol Chem 270 1995 14255 14258
13. J. Das, C.H. Chen, L. Yang, L. Cohn, P. Ray, and A. Ray A critical role for NF-κB in GATA3 expression and TH2 differentiation in allergic airway inflammation Nat Immunol 2 2001 45 50
14. Y.Y. Liu, S.K. Liao, C.C. Huang, Y.H. Tsai, D.A. Quinn, and L.F. Li Role for nuclear factor-κB in augmented lung injury because of interaction between hyperoxia and high stretch ventilation Transl Res 154 2009 228 240
15. C.H. Chiang, H.I. Pai, and S.L. Liu Ventilator-induced lung injury (VILI) promotes ischemia/reperfusion lung injury (I/R) and NF-κB antibody attenuates both injuries Resuscitation 79 2008 147 154
16. R. Drake, K.A. Gaar, and A.E. Taylor Estimation of the filtration coefficient of pulmonary exchange vessels Am J Physiol 234 1978 H266 H274
17. C.H. Chiang, C.H. Chuang, and S.L. Liu Apocynin attenuates ischemia-reperfusion lung injury in an isolated and perfused rat lung model Transl Res 158 2011 17 29
18. C.H. Chiang, K. Hsu, H.C. Yan, H.J. Harn, and D.M. Chang PGE1, dexamethasone, U-74389G, or Bt2-cAMP as an additive to promote protection by UW solution in I/R injury J Appl Physiol 83 1997 583 590
19. R.S. Croner, W. Hohenberger, and M.G. Jeschke Hepatic gene expression during endotoxemia J Surg Res 154 2009 126 134
20. S. Hagiwara, H. Iwasaka, and A. Hasegawa et al. Adenosine diphosphate receptor antagonist clopidogrel sulfate attenuates LPS-induced systemic inflammation in a rat model Shock 35 2011 289 292
21. H. Seki, S. Tasaka, and K. Fukunaga et al. Effect of Toll-like receptor 4 inhibitor on LPS-induced lung injury Inflamm Res 59 2010 837 845
22. C.F. Chian, C.H. Chiang, and C. Yuan-Jung et al. Apocynin attenuates lipopolysaccharide -induced lung injury in an isolated and perfused rat lung model Shock 38 2010 196 202
23. A. Kapoor, Y. Shintani, and M. Collino et al. Protective role of peroxisome proliferator -activated receptor-β/δ in septic shock Am J Respir Crit Care Med 182 2010 1506 1515
24. T.T. Nguyen, P.T. Foteinou, S.E. Calvano, S.F. Lowry, and I.P. Androulakis Computational identification of transcriptional regulators in human endotoxemia PLoS One 6 2011 e18889
25. D. Ansaldi, E.A. Hod, and F. Stellari et al. Imaging pulmonary NF-κB activation and therapeutic effects of MLN120B and TDZD-8 PLoS One 6 2011 e25093
26. F. Yunhe, L. Bo, and F. Xiaosheng et al. The effect of magnolol on the Toll-like receptor 4/nuclear factor κB signaling pathway in lipopolysaccharide-induced acute lung injury in mice Eur J Pharmacol 689 2012 255 261
27. X. Xu, Q. Xie, and Y. Shen et al. Involvement of mannose receptor in the preventive effects of mannose in lipopolysaccharide-induced acute lung injury Eur J Pharmacol 641 2010 229 237
28. G. Liu, Y.J. Park, Y. Tsuruta, E. Lorne, and E. Abraham p53 Attenuates lipopolysaccharide -induced NF-κB activation and acute lung injury J Immunol 182 2009 5063 5071
29. A. Rahman, and F. Fazal Blocking NF-κB: an inflammatory issue Proc Am Thorac Soc 8 2011 497 503
30. J.A. Nick, N.J. Avdi, and S.K. Young et al. Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils J Clin Invest 103 1999 851 858
31. T.R. Torgerson, A.D. Colosia, J.P. Donahue, Y.Z. Lin, and J. Hawiger Regulation of NF-κB, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-κB p50 J Immunol 161 1998 6084 6092
32. D. Liu, X.Y. Liu, and D. Robinson et al. Suppression of Staphylococcal Enterotoxin B-induced Toxicity by a Nuclear Import Inhibitor J Biol Chem 279 2004 19239 19246
33. S.A. McCracken, K. Hadfield, Z. Rahimi, E.D. Gallery, and J.M. Morris NF-κB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy Eur J Immunol 37 2007 1386 1396
34. A.W. O'Sullivan, J.H. Wang, and H.P. Redmond NF-κB and p38 MAPK inhibition improve survival in endotoxin shock and in a cecal ligation and puncture model of sepsis in combination with antibiotic therapy J Surg Res 152 2009 46 53
35. J.Y. Duffy, K.M. McLean, J.M. Lyons, A.J. Czaikowski, C.J. Wagner, and J.M. Pearl Modulation of nuclear factor-κB improves cardiac dysfunction associated with cardiopulmonary bypass and deep hypothermic circulatory arrest Crit Care Med 37 2009 577 583
36. A.J. Smuder, M.B. Hudson, W.B. Nelson, A.N. Kavazis, and S.K. Powers Nuclear factor-κB signaling contributes to mechanical ventilation-induced diaphragm weakness Crit Care Med 40 2012 927 934