Eutirucallin, a RIP-2 type lectin from the latex of Euphorbia tirucalli L. presents proinflammatory properties

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Santana, Sanzio Silva ^a   Gennari Cardoso, Margareth Leitão ^a   Carvalho, Fernanda Caroline ^b   Roque Barreira, Maria Cristina ^b   Santiago, André Da Silva ^a   Alvim, Fátima Cerqueira ^a   Pirovani, Carlos Priminho ^a  

^a DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ABRIN; CALCIUM ION; CINNAMOMIN; EBULIN; EUTIRUCALLIN; GALACTOSE; LATEX; PLANT LECTIN; POLYPEPTIDE; PULCHELLIN; RIBOSOME INACTIVATING PROTEIN 2; RICIN; UNCLASSIFIED DRUG; VISCUMIN; VOLKENSIN; CALCIUM; DISULFIDE; EUTIRUCALLIN PROTEIN, EUPHORBIA TIRUCALLI; LACTOSE; LECTIN; N ACETYLGALACTOSAMINE; PEPTIDE; PLANT EXTRACT;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISULFIDE BOND; ERYTHROCYTE; EUPHORBIA; EUPHORBIA TIRUCALLI; HEMAGGLUTINATION; HUMAN; HUMAN CELL; INFLAMMATION; ION EXCHANGE CHROMATOGRAPHY; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN SUBUNIT; SEQUENCE HOMOLOGY; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; MACROPHAGE; PROTEIN TERTIARY STRUCTURE; RIBOSOME; TEMPERATURE;

ACETYLGALACTOSAMINE; CALCIUM; DISULFIDES; ERYTHROCYTES; EUPHORBIA; GALACTOSE; HUMANS; INFLAMMATION; LACTOSE; LATEX; LECTINS; MACROPHAGES; PEPTIDES; PLANT EXTRACTS; PLANT LECTINS; PROTEIN STRUCTURE, TERTIARY; RIBOSOMES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE;

EID: 84895886711     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088422     Document Type: Article

References (33)

1. Souza MA, Amâncio-Pereira F, Cardoso CRB, Silva AGd, Silva EG, et al. (2005) Isolation and partial characterization of a D-galactose-binding lectin from the latex of Synadenium carinatum. Brazilian Archives of Biology and Technology 48: 705-716.
2. Furstenberger G, Hecker E (1985) On the active principles of the spurge family (Euphorbiaceae). XI. [1] The skin irritant and tumor promoting diterpene esters of Euphorbia tirucalli L. originating from South Africa. Z Naturforsch C 40: 631-646.
3. Yamamoto Y, Mizuguchi R, Yamada Y (1981) Chemical constituents of cultured cells of Euphorbia tirucalli and E. millii. Plant Cell Reports 1: 29-30.
4. Tiwari S, Singh A (2005) Alterations in carbohydrates and the protein metabolism of the harmful freshwater vector snail Lymnaea acuminata induced by the Euphorbia tirucalli latex extract. Environ Res 99: 378-386. (Pubitemid 41676848)
5. Rahuman A, Gopalakrishnan G, Venkatesan P, Geetha K (2008) Larvicidal activity of some Euphorbiaceae plant extracts against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae). Parasitology Research 102: 867-873.
6. Brasileiro BG, Pizziolo VR, Raslan DS, Jamal CM, Silveira D (2006) Antimicrobial and cytotoxic activities screening of some Brazilian medicinal plants used in Governador Valadares district. Revista Brasileira de Ciências Farmacêuticas 42: 195-202.
7. Valadares MC, Carrucha SG, Accorsi W, Queiroz MLS (2006) Euphorbia tirucalli L. modulates myelopoiesis and enhances the resistance of tumour-bearing mice. International Immunopharmacology 6: 294-299. (Pubitemid 43052827)
8. MacNeil A, Sumba OP, Lutzke ML, Moormann A, Rochford R (2003) Activation of the Epstein-Barr virus lytic cycle by the latex of the plant Euphorbia tirucalli. Br J Cancer 88: 1566-1569. (Pubitemid 36713783)
9. Pajic I, Kljajic Z, Dogovic N, Sladic D, Juranic Z, et al. (2002) A novel lectin from the sponge Haliclona cratera: isolation, characterization and biological activity. Comparative Biochemistry and Physiology Part C: Toxicology &Pharmacology 132: 213-221. (Pubitemid 34775065)
10. Coelho LCBB, da Silva MBR (2000) Simple method to purify milligram quantities of the galactose-specific lectin from the leaves of Bauhinia monandra. John Wiley & Sons, Ltd. pp. 295-300.
11. Lis H, Sharon N (1998) Lectins: Carbohydrate-Specific Proteins That Mediate Cellular Recognition Chemical Reviews 98: 637-674. (Pubitemid 128631438)
12. Stirpe F, Gasperi-Campani A, Barbieri L, Falasca A, Abbondanza A, et al. (1983) Ribosome-inactivating proteins from the seeds of Saponaria officinalis L. (soapwort), of Agrostemma githago L. (corn cockle) and of Asparagus officinalis L. (asparagus), and from the latex of Hura crepitans L. (sandbox tree). Biochem J 216: 617-625.
13. Ambrosi M, Cameron NR, Davis BG (2005) Lectins: tools for the molecular understanding of the glycocode. Org Biomol Chem 3: 1593-1608. (Pubitemid 40683078)
14. Sharon N, Lis H (2001) The structural basis for carbohydrate recognition by lectins. Adv Exp Med Biol 491: 1-16. (Pubitemid 32595113)
15. Xu H, Liu WY (2004) Cinnamomin - a versatile type II ribosome- inactivating protein. Acta Biochim Biophys Sin (Shanghai) 36: 169-176. (Pubitemid 38639049)
16. Olsnes S, Saltvedt E, Pihl A (1974) Isolation and Comparison of Galactose-binding Lectins from Abrus precatorius and Ricinus communis. Journal of Biological Chemistry 249: 803-810.
17. Goldstein J (1989) Conversion of ABO blood groups. Transfus Med Ver 3: 206-212.
18. Machuka JS, Okeola OG, Van Damme Els JM, Chrispeels MJ, Van Leuven F, et al. (1999) Isolation and partial characterisation of galactose-specific lectins from African yam beans, Sphenostyles stenocarpa Harms. Phytochemistry 51: 721-728. (Pubitemid 29289189)
19. Wititsuwannakul R, Wititsuwannakul D, Sakulborirug C (1998) A lectin from the bark of the rubber tree (Hevea brasiliensis). Phytochemistry 47: 183-187. (Pubitemid 28029039)
20. Konozy EHE, Bernardes ES, Rosa C, Faca V, Greene LJ, et al. (2003) Isolation, purification, and physicochemical characterization of a -galactose-binding lectin from seeds of Erythrina speciosa. Archives of Biochemistry and Biophysics 410: 222-229. (Pubitemid 36259821)
21. Emmerich C, Helliwell JR, Redshaw M, Naismith JH, Harrop SJ, et al. (1994) High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A. Acta Crystallographica Section D 50: 749-756. (Pubitemid 2143423)
22. Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR (2004) Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose. Glycobiology 14: 923-929. (Pubitemid 39264015)
23. Loyola W, Custodio LA, Felipe I, Conchon-Costa I, Carvalho PG, et al. (2012) Artin M enhances TNF-alpha production and phagocytosis of Candida albicans mediated by dectin-1 and mannose receptors. Int Immunopharmacol 12: 378-383.
24. Elifio-Esposito S, Tomazeli L, Schwartz C, Gimenez AP, Fugii GM, et al. (2011) Human neutrophil migration and activation by BJcuL, a galactose binding lectin purified from Bothrops jararacussu venom. BMC Immunol 12: 10.
25. Panunto-Castelo A, Souza MA, Roque-Barreira MC, Silva JS (2001) KM(+), a lectin from Artocarpus integrifolia, induces IL-12 p40 production by macrophages and switches from type 2 to type 1 cell-mediated immunity against Leishmania major antigens, resulting in BALB/c mice resistance to infection. Glycobiology 11: 1035-1042. (Pubitemid 34162765)
26. Hartley MR, Lord JM (2004) Cytotoxic ribosome-inactivating lectins from plants. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 1701: 1-14. (Pubitemid 39140781)
27. Sandvig K, van Deurs B (1996) Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin. Physiological Reviews 76: 949-966. (Pubitemid 26346812)
28. Yamasaki C, Nishikawa K, Zeng X-T, Katayama Y, Natori Y, et al. (2004) Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin. Biochimica et Biophysica Acta (BBA) - General Subjects 1671: 44-50. (Pubitemid 38327128)
29. Loris R (2002) Principles of structures of animal and plant lectins. Biochimica et Biophysica Acta (BBA) - General Subjects 1572: 198-208.
30. Sharon N, Lis H (2002) How Proteins Bind Carbohydrates: Lessons from Legume Lectins. Journal of Agricultural and Food Chemistry 50: 6586-6591. (Pubitemid 35216777)
31. Barbieri L, Falasca A, Franceschi C, Licastro F, Rossi CA, et al. (1983) Purification and properties of two lectins from the latex of the euphorbiaceous plants Hura crepitans L. (sand-box tree) and Euphorbia characias L. (Mediterranean spurge). Biochem J 215: 433-439.
32. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72: 248-254.
33. Laemmli UK (1970) Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4. Nature 227: 680-685.