Activation of the Epstein-Barr virus lytic cycle by the latex of the plant Euphorbia tirucalli

British Journal of Cancer

Volumn 88, Issue 10, 2003, Pages 1566-1569

  MacNeil, A ^a,d   Sumba, O P ^b   Lutzke, M L ^a   Moormann, A ^c   Rochford, R ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CENTERS FOR DIS CONTR AND PREV   (United States)

Author keywords

Burkitt's lymphoma; E. tirucalli; Epstein Barr virus; Viral gene expression

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; EUPHORBIA EXTRACT; PROTEIN KINASE C INHIBITOR;

ARTICLE; BURKITT LYMPHOMA; CONTROLLED STUDY; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; EPSTEIN BARR VIRUS; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LYMPHOMA CELL LINE; PRIORITY JOURNAL; RIBONUCLEASE PROTECTION ASSAY; VIRUS CARCINOGENESIS; VIRUS REACTIVATION;

BURKITT LYMPHOMA; ENVIRONMENTAL EXPOSURE; EUPHORBIA; GENE EXPRESSION REGULATION; HERPESVIRUS 4, HUMAN; HUMANS; LATEX; TUMOR CELLS, CULTURED;

EID: 0037778205     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600929     Document Type: Article

References (17)

1. Baumann M, Mischak H, Dammeier S, Kolch W, Gires O, Pich D, Zeidler R, Delecluse HJ, Hammerschmidt W (1998) Activation of the Epstein-Barr virus transcription factor BZLF1 by 12-O-tetradecanoylphorbol-13-acetate-induced phosphorylation. J Virol 72: 8105-8114
2. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thyocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
3. Crawford DH (2001) Biology and disease associations of Epstein-Barr virus. Phil Trans R Soc Land B Biol Sci 356: 461-473
4. de-The G (1985) Epstein-Barr virus and Burkitt's lymphoma worldwide: the causal relationship revisited. IARC Sci Publ 60: 165-176
5. de-The G, Geser A, Day NE, Tukei PM, Williams EH, Beri DP, Smith PG, Dean AG, Bronkamm GW, Feorino P, Henle W (1978) Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study. Nature 274: 756-761
6. Imai S, Sugiura M, Mizuno F, Ohigashi H, Koshimizu K, Chiba S, Osato T (1994) African Burkitt's lymphoma: a plant, Euphorbia tirucalli, reduces Epstein-Barr virus-specific cellular immunity. Anticancer Res 14: 933-936
7. Labrecque LG, Xue SA, Kazembe P, Phillips J, Lampert I, Wedderburn N, Griffin BE (1999) Expression of Epstein-Barr virus lytically related genes in African Burkitt's lymphoma: correlation with patient response to therapy. Int J Cancer 81: 6-11
8. Miller G (1990) The switch between latency and replication of Epstein-Barr virus. J Infect Dis 161: 833-844
9. Mizuno F, Koizumi S, Osato T, Kokwaro JO, Ito Y (1983) Chinese and African Euphorbiaceae plant extracts: markedly enhancing effect on Epstein-Barr virus-induced transformation. Cancer Lett 19: 199-205
10. Morrow Jr RH (1985) Epidemiological evidence for the role of falciparum malaria in the pathogenesis of Burkitt's lymphoma. IARC Sci Publ 60: 177-186
11. Ong SK, Xue SA, Molyneux E, Broadhead RL, Borgstein E, Ng MH, Griffin BE (2001) African Burkitt's lymphoma: a new perspective. Trans R Soc Trop Med Hyg 95: 93-96
12. Osato T, Imai S, Kinoshita T, Aya T, Sugiura M, Koizumi S, Mizuno F (1990) Epstein-Barr virus, Burkitt's lymphoma, and an African tumor promoter. Adv Exp Med Biol 278: 147-150
13. Osato T, Mizuno F, Imai S, Aya T, Koizumi S, Kinoshita T, Tokuda H, Ito Y, Hirai N, Hirota M, Ohigashi H, Koshimizu K, Kofi-Tsekpo WM, Were JBO, Mugambi M (1987) African Burkitt's lymphoma and an Epstein-Barr virus-enhancing plant Euphorbia tirucalli. Lancet 1: 1257-1258
14. Rochford R, Cannon MJ, Sabbe RE, Adusumilli K, Picchio G, Glynn JM, Noonan DJ, Mosier DE, Hobbs MV (1997) Common and idiosyncratic patterns of cytokine gene expression by Epstein-Barr virus transformed human B cell lines. Viral Immunol 10: 183-195
15. Rochford R, Mosier DE (1995) Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes. J Virol 69: 150-155
16. van den Bosch C, Griffin BE, Kazembe P, Dziweni C, Kadzamira L (1993) Are plant factors a missing link in the evolution of endemic Burkitt's lymphoma. Br J Cancer 68: 1232-1235
17. zur Hausen H, O'Neill FJ, Freese UK, Hecker E (1978) Persisting oncogenic herpesvirus induced by the tumour promotor TPA. Nature 272: 373-375