In vitro activity and in vivo animal model efficacy of IB-367 alone and in combination with imipenem and colistin against Gram-negative bacteria

Peptides

Volumn 55, Issue , 2014, Pages 17-22

  Simonetti, Oriana ^a   Cirioni, Oscar ^a   Ghiselli, Roberto ^b   Orlando, Fiorenza ^c   Silvestri, Carmela ^a   Mazzocato, Susanna ^a   Kamysz, Wojciech ^d   Kamysz, Elzbieta ^e   Provinciali, Mauro ^c   Giacometti, Andrea ^a   Guerrieri, Mario ^b   Offidani, Annamaria ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b OSPEDALI RIUNITI   (Italy)

^c INRCA   (Italy)

^d MEDICAL UNIVERSITY OF GDANSK   (Poland)

^e UNIVERSITY OF GDA SK   (Poland)

Author keywords

Animal model; Escherichia coli; IB 367; Pseudomonas aeruginosa; Wound infection

Indexed keywords

COLISTIN; IMIPENEM; ISEGANAN; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; ANTIMICROBIAL PEPTIDE IB-367;

ACINETOBACTER BAUMANNII; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; BAGG ALBINO MOUSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; IN VITRO STUDY; IN VIVO STUDY; KLEBSIELLA PNEUMONIAE; MALE; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; WOUND INFECTION; ANIMAL; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; TOPICAL DRUG ADMINISTRATION;

ACINETOBACTER BAUMANNII; ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; COLISTIN; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ESCHERICHIA COLI; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; IMIPENEM; INJECTIONS, INTRAPERITONEAL; KLEBSIELLA PNEUMONIAE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA;

EID: 84895802207     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.01.029     Document Type: Article

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