The efficacy of the quorum sensing inhibitor FS8 and tigecycline in preventing prosthesis biofilm in an animal model of staphylococcal infection

International Journal of Molecular Sciences

Volumn 14, Issue 8, 2013, Pages 16321-16332

  Simonetti, Oriana ^a   Cirioni, Oscar ^a   Mocchegiani, Federico ^a   Cacciatore, Ivana ^b   Silvestri, Carmela ^a   Baldassarre, Leonardo ^b   Orlando, Fiorenza ^c   Castelli, Pamela ^a   Provinciali, Mauro ^c   Vivarelli, Marco ^a   Fornasari, Erika ^b   Giacometti, Andrea ^a   Offidani, Annamaria ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c INRCA   (Italy)

Author keywords

Bacterial biofilm; FS8; Lipopeptides; Tigecycline; Vascular graft infection

Indexed keywords

ANTIINFECTIVE AGENT; FS 8; TIGECYCLINE; UNCLASSIFIED DRUG;

AGAR MEDIUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIUM ADHERENCE; BIOFILM; CONTROLLED STUDY; DACRON VASCULAR PROSTHESIS; DRUG EFFICACY; DRUG STRUCTURE; GROWTH INHIBITION; IN VITRO STUDY; INFECTION PREVENTION; MALE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PATHOGEN LOAD; PROSTHESIS INFECTION; QUORUM SENSING; RAT; STAPHYLOCOCCUS INFECTION; ULTRASOUND;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; DISEASE MODELS, ANIMAL; MALE; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MINOCYCLINE; OLIGOPEPTIDES; POLYETHYLENE TEREPHTHALATES; PROSTHESIS-RELATED INFECTIONS; PROTEIN BINDING; QUORUM SENSING; RATS; RATS, WISTAR; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84886739045     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140816321     Document Type: Article

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