The ERK1/2 signaling pathway regulates 11beta-hydroxysteroid dehydrogenase type 2 expression in human trophoblast cells through a transcriptional mechanism

Biology of Reproduction

Volumn 89, Issue 4, 2013, Pages

  Guan, Haiyan ^a   Sun, Kang ^b   Yang, Kaiping ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b FUDAN UNIVERSITY   (China)

Author keywords

ERK1 2; Gene expression; Glucocorticoid receptor; Glucocorticoids; MAPK; Placenta; Pregnancy; Signal transduction; Trophoblast

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 11BETA HYDROXYSTEROID DEHYDROGENASE 2; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CADMIUM; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PLACENTA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TROPHOBLAST;

ERK1/2; GENE EXPRESSION; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOIDS; MAPK; PLACENTA; PREGNANCY; SIGNAL TRANSDUCTION; TROPHOBLAST;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; CADMIUM CHLORIDE; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; GENES, REPORTER; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TROPHOBLASTS;

EID: 84895796109     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.110924     Document Type: Article

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