Regulation of 11β-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen, and the cyclic adenosine 5'-monophosphate pathway in cultured human placental and chorionic trophoblasts

Biology of Reproduction

Volumn 58, Issue 6, 1998, Pages 1379-1384

  Sun, Kang ^a,c   Yang, Kaiping ^b   Challis, John R G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ADENYLATE CYCLASE; CORTISONE; CYCLIC AMP; ESTROGEN; FORSKOLIN; HYDROCORTISONE; MESSENGER RNA; MIFEPRISTONE; ONAPRISTONE; OXIDOREDUCTASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROGESTERONE; PROTEIN KINASE C; TRILOSTANE; ESTRADIOL; HYDROXYSTEROID DEHYDROGENASE;

ARTICLE; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; NORTHERN BLOTTING; PLACENTA; PRIORITY JOURNAL; RADIOIMMUNOASSAY; TROPHOBLAST; CELL CULTURE; CHORION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PREGNANCY;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; CELLS, CULTURED; CHORION; CYCLIC AMP; ESTRADIOL; FEMALE; FORSKOLIN; GENE EXPRESSION REGULATION; HUMANS; HYDROXYSTEROID DEHYDROGENASES; PLACENTA; PREGNANCY; PROGESTERONE; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TROPHOBLASTS;

EID: 0031596304     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod58.6.1379     Document Type: Article

References (33)

1. Monder C, Shackleton CHL. 11β-Hydroxysteroid dehydrogenase: fact or fancy? Steroids 1984; 44:383-417.
2. Kenouch S, Coutry N, Farman N, Bonvalet JP. Multiple patterns of 11β-hydroxysteroid dehydrogenase catalytic activity along the mammalian nephron. Kidney Int 1992; 42:56-60.
3. Brown RW, Chapman KE, Edwards CR, Seckle JR. Human placental 11β-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoforms. Endocrinology 1993; 132:2614-2621.
4. Seckl JR. 11β-Hydroxysteroid dehydrogenase isoforms and their implications for blood pressure regulation. Eur J Clin Invest 1993; 23: 589-601.
5. Krozowski Z, Maguire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK. Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol & Metab 1995; 80:2203-2209.
6. Brown RW, Chapman KE, Murad P, Edwards CRW, Seckl JR. Purification of 11β-hydroxysteroid dehydrogenase type 2 from human placenta utilizing a novel affinity labeling technique. Biochem J 1996; 313:997-1005.
7. Albiston AL, Obeyesekere V, Smith RE, Krozowski ZS. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 1994; 105:R11-R17.
8. Sun K, Yang K, Challis JRG. Differential expression of 11β-hydroxysteroid dehydrogenase type 1 and 2 in human placenta and fetal membranes. J Clin Endocrinol & Metab 1997; 82:300-305.
9. Seckl JR, Benediktssion R, Linsay RS, Brown RW. Placental 11β-hydroxysteroid dehydrogenase and the programming of hypertension. J Steroid Biochem Mol Biol 1995; 55:447-445.
10. Stewart PM, Rogerson FM, Mason JI. Type 2 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis. J Clin Endocrinol & Metab 1995; 80:885-890.
11. Reinisch JM, Simon NG, Karow WG, Gandelman R. Prenatal exposure to prednisone in humans and animals retards intrauterine growth. Science 1978; 202:436-438.
12. Barker DJP, Osmond C, Winter PD, Margetts B. Weight in infancy and death from ischemic heart disease. Lancet 1989; 2:577-580.
13. Pepe GJ, Albrecht ED. Actions of placental and fetal adrenal steroid hormones in primate pregnancy. Endocr Rev 1995; 16:608-647.
14. Baggia S, Albrecht E, Pepe G. Regulation of 11β-hydroxysteroid dehydrogenase activity in the baboon placenta by estrogen. Endocrinology 1990; 126:2742-2748.
15. Murphy BEP. Specificity of human 11β-hydroxysteroid dehydrogenase. J Steroid Biochem 1981; 14:807-809.
16. Low SC, Assaad SN, Chapman KE, Edwards CRW, Seckl JR. Regulation of 11β-hydroxysteroid dehydrogenase by sex steroids in vivo: further evidence for the existence of a second dehydrogenase in rat kidney. J Endocrinol 1993; 139:27-35.
17. Benediktsson R, Smith JC. Seckl JR. Evaluation of JEG-3 cells as a model for human placental 11β-hydroxysteroid dehydrogenase. In: Program and Abstract of 10th International Congress of Endocrinology Vol. I; 1996: 192.
18. Pasquarette MM, Stewart PM, Ricketts ML, Imaishi K, Mason JI. Regulation of 11β-hydroxysteroid dehydrogenase type 2 activity and mRNA in human chorion carcinoma cells. J Mol Endocrinol 1996; 16:269-275.
19. Kliman HJ, Nestler JE, Sermasi E, Sanger JM, Strauss III JF. Purification, characterization and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 1986; 118:1567-1582.
20. Sun K, Smith R, Robinson PJ. Basal and KCl-stimulated corticotropin-releasing hormone release from human placental syncytiotrophoblasts is inhibited by sodium nitroprusside. J Clin Endocrinol & Metab 1994; 79:519-524.
21. Cheung PYC, Walton JC, Tai H-H, Riley SC, Challis JRG. Immunohistochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua and placenta. Am J Obstet Gynecol 1990; 163:1445-1449.
22. Sun K, Yang K, Challis JRG. Differential regulation of 11β-hydroxysteroid dehydrogenase type I and II by nitric oxide in cultured human placental syncytiotrophoblast and chorionic cell preparation. Endocrinology 1997; 138:4912-4920.
23. Shaw DA, Quincey RV. The preparation of tritium-labelled cortisol metabolites of high specific activity. J Endocrinol 1963; 26:577-578.
24. 1-24 administration to one twin on the endocrine and uterine activity changes during twin pregnancy in sheep. Biol Reprod 1988; 38:135-142.
25. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources nch in ribonuclease. Biochemistry 1979; 18:5249-5299.
26. Yang K, Khalil MW, Strutt BJ, Killinger DW. 11β-Hydroxysteroid dehydrogenase 1 activity and gene expression in human adipose stromal cells: effect on aromatase activity. J Steroid Biochem Mol Bio 1997; 60:247-253.
27. Lopez-Bernal A, Flint APF, Anderson ABP, Turnbull AC. 11β-Hydroxysteroid dehydrogenase activity in human placenta and decidua. J Steroid Biochem 1980; 13:1081-1087.
28. Mitchell BF, Cruickshank B, McLean D, Challis JRG. Local modulation of progesterone production in human fetal membranes. J Clin Endocrinol & Metab 1982; 55:1237-1239.
29. Souness GW, Latif SA, Laurenzo JL, Morris DJ. 11α- and 11β-Hydroxyprogesterone, potent inhibitors of 11β-hydroxysteroid dehydrogenase (isoforms 1 and 2), confer marked mineralocorticoid activity on corticosterone in the ADX rat. Endocrinology 1995; 136:1809-1812.
30. Pepe GJ, Waddell BJ, Burch MG, Albrecht ED. Interconversion of cortisol and cortisone in the baboon placenta at midgestation: expression of 11β-hydroxysteroid dehydrogenase type 1 messenger RNA. J Steroid Biochem Mol Biol 1996; 58:403-410.
31. Robinson BG, Emanuel RL, Frim DM, Majzoub JA. Glucocorticoid stimulates corticotropin-releasing hormone gene expression in human placenta. Pro Natl Acad Sci USA 1988; 85:5244-5248.
32. Jones SA, Challis JRG. Steroid, corticotropin-releasing hormone, ACTH and prostaglandin interaction in the amnion and placenta of early pregnancy in man. J Endocrinol 1990; 68:825-830.
33. Zakar T, Hirst JJ, Mijovic JE, Olson DM. Glucocorticoids stimulate the expression of prostaglandin endoperoxide H synthase-2 in amnion cells. Endocrinology 1995; 136:1610-1619.