Placental 11β-hydroxysteroid dehydrogenase: Barrier to maternal glucocorticoids

Reviews of Reproduction

Volumn 2, Issue 3, 1997, Pages 129-132

  Yang, Kaiping ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; CORTISONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID; HYDROCORTISONE;

BABOON; BLOOD PLACENTA BARRIER; CORTICOSTERONE BLOOD LEVEL; ENZYME LOCALIZATION; GUINEA PIG; HUMAN; HYDROCORTISONE BLOOD LEVEL; INTRAUTERINE GROWTH RETARDATION; MAMMAL; NONHUMAN; PLACENTA; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHEEP; SHORT SURVEY; SPECIES DIFFERENCE; SWINE; SYNCYTIOTROPHOBLAST;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; BIOLOGICAL TRANSPORT; CORTICOSTERONE; FEMALE; HUMANS; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASES; MATERNAL-FETAL EXCHANGE; PLACENTA; PREGNANCY; SPECIES SPECIFICITY;

ANIMALIA; CAVIA PORCELLUS; MAMMALIA; OVIS ARIES; PAPIO HAMADRYAS; RODENTIA; SUS SCROFA;

EID: 0030858010     PISSN: 13596004     EISSN: None     Source Type: Journal    
DOI: 10.1530/ror.0.0020129     Document Type: Short Survey

References (9)

1. Benediktsson R, Calder AA, Edwards CRW and Seckl JR (1997) Placental 11β-hydroxysteroid dehydrogenase - a key regulator of fetal glucocorticoid exposure Clinical Endocrinology 46 161-166
2. Brown RW, Chapman KE, Kotelevtsev Y, Yau JLW, Lindsay RS, Brett L, Leckie C, Murad P, Lyons V, Mullins JJ, Edwards CRW and Seckl JR (1996) Cloning and production of antisera to human placental 11β-hydroxysteroid dehydrogenase type 2 Biochemistry Journal 313 1007-1017
3. Burton PJ, Smith RE, Krozowski ZS and Waddell BJ (1996) Zonal distribution of 11β-hydroxysteroid dehydrogenase types 1 and 2 mRNA expression in the rat placenta and decidua during late pregnancy Biology of Reproduction 55 1023-1028
4. Campbell LE, Yu M and Yang K (1996) Ovine 11β-hydroxysteroid dehydrogenase type 2 gene predicts a protein distinct from that deduced by the cloned kidney cDNA at the C-terminus Molecular and Cellular Endocrinology 119 113-118
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6. Edwards CR, Benediktsson R, Lindsay RS and Seckl JR (1993) Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? Lancet 341 355-357
7. Funder JW, Pearce PT, Smith R and Smith AI (1988) Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated Science 242 583-585
8. Klemcke HG and Christenson RK (1996) Porcine placental 11β-hydroxysteroid dehydrogenase activity Biology of Reproduction 55 217-223
9. Krozowski Z, Maguire JA, Stein-Oakley AN, Dowling J, Smith RE and Andrews RK (1995) Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta Journal of Clinical Endocrinology and Metabolism 80 2203-2209