메뉴 건너뛰기




Volumn 22, Issue 3, 2014, Pages 964-970

FTO genetic variants and risk of obesity and type 2 diabetes: A meta-analysis of 28,394 Indians

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ALLELE; ARTICLE; BODY MASS; FTO GENE; GENDER; GENETIC ASSOCIATION; GENETIC RISK; GENETIC TRAIT; GENETIC VARIABILITY; HUMAN; INDIAN; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; WAIST HIP RATIO;

EID: 84895791445     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20606     Document Type: Article
Times cited : (43)

References (39)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H,. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 2
    • 78049337953 scopus 로고    scopus 로고
    • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    • Speliotes EK, Willer CJ, Berndt SI, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010; 42: 937-948.
    • (2010) Nat Genet , vol.42 , pp. 937-948
    • Speliotes, E.K.1    Willer, C.J.2    Berndt, S.I.3
  • 3
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 4
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115.
    • (2007) PLoS Genet , vol.3
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3
  • 5
    • 58149163141 scopus 로고    scopus 로고
    • Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
    • Thorleifsson G, Walters GB, Gudbjartsson DF, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009; 41: 18-24.
    • (2009) Nat Genet , vol.41 , pp. 18-24
    • Thorleifsson, G.1    Walters, G.B.2    Gudbjartsson, D.F.3
  • 6
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41: 25-34.
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3
  • 7
    • 47749128415 scopus 로고    scopus 로고
    • Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk
    • Sanghera DK, Ortega L, Han S, et al. Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Med Genet 2008; 9: 59.
    • (2008) BMC Med Genet , vol.9 , pp. 59
    • Sanghera, D.K.1    Ortega, L.2    Han, S.3
  • 8
    • 58149470594 scopus 로고    scopus 로고
    • FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians
    • Yajnik CS, Janipalli CS, Bhaskar S, et al. FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians. Diabetologia 2009; 52: 247-252.
    • (2009) Diabetologia , vol.52 , pp. 247-252
    • Yajnik, C.S.1    Janipalli, C.S.2    Bhaskar, S.3
  • 9
    • 80155195962 scopus 로고    scopus 로고
    • Common variants of FTO and the risk of obesity and type 2 diabetes in Indians
    • Chauhan G, Tabassum R, Mahajan A, et al. Common variants of FTO and the risk of obesity and type 2 diabetes in Indians. J Human Genet 2011; 56: 720-726.
    • (2011) J Human Genet , vol.56 , pp. 720-726
    • Chauhan, G.1    Tabassum, R.2    Mahajan, A.3
  • 10
    • 83155173107 scopus 로고    scopus 로고
    • Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of Type 2 diabetes and related traits in Indians
    • Janipalli CS, Kumar MV, Vinay DG, et al. Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of Type 2 diabetes and related traits in Indians. Diabet Med 2012; 29: 121-127.
    • (2012) Diabet Med , vol.29 , pp. 121-127
    • Janipalli, C.S.1    Kumar, M.V.2    Vinay, D.G.3
  • 11
    • 78650606532 scopus 로고    scopus 로고
    • Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79)
    • Ramya K, Radha V, Ghosh S, Majumder PP, Mohan V,. Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79). Diabetes Technol Therap 2011; 13: 33-42.
    • (2011) Diabetes Technol Therap , vol.13 , pp. 33-42
    • Ramya, K.1    Radha, V.2    Ghosh, S.3    Majumder, P.P.4    Mohan, V.5
  • 12
    • 81355151686 scopus 로고    scopus 로고
    • Associations of FTO and MC4R variants with obesity traits in Indians and the role of Rural/Urban environment as a possible effect modifier
    • Taylor AE, Sandeep MN, Janipalli CS, et al. Associations of FTO and MC4R variants with obesity traits in Indians and the role of Rural/Urban environment as a possible effect modifier. J Obes 2011; 2011: 307542.
    • (2011) J Obes , vol.2011 , pp. 307542
    • Taylor, A.E.1    Sandeep, M.N.2    Janipalli, C.S.3
  • 13
    • 84865614768 scopus 로고    scopus 로고
    • Common genetic variants and central adiposity among Asian-Indians
    • (9).
    • Moore SC, Gunter MJ, Daniel CR, et al. Common genetic variants and central adiposity among Asian-Indians. Obesity 2011; 20 (9): 1902-1908.
    • (2011) Obesity , vol.20 , pp. 1902-1908
    • Moore, S.C.1    Gunter, M.J.2    Daniel, C.R.3
  • 14
    • 84868211532 scopus 로고    scopus 로고
    • Associations of variants in FTO and near MC4R with obesity traits in South Asian Indians
    • (11).
    • Vasan SK, Fall T, Neville MJ, et al. Associations of variants in FTO and near MC4R with obesity traits in South Asian Indians. Obesity 2011; 20 (11): 2268-2277.
    • (2011) Obesity , vol.20 , pp. 2268-2277
    • Vasan, S.K.1    Fall, T.2    Neville, M.J.3
  • 15
    • 55849137212 scopus 로고    scopus 로고
    • Obesity and the metabolic syndrome in developing countries
    • Misra A, Khurana L,. Obesity and the metabolic syndrome in developing countries. J Clin Endocrinol Metab 2008; 93: S9-S30.
    • (2008) J Clin Endocrinol Metab , vol.93
    • Misra, A.1    Khurana, L.2
  • 16
    • 84862564504 scopus 로고    scopus 로고
    • Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
    • Li H, Kilpelainen TO, Liu C, et al. Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia 2012; 55: 981-995.
    • (2012) Diabetologia , vol.55 , pp. 981-995
    • Li, H.1    Kilpelainen, T.O.2    Liu, C.3
  • 17
    • 0035990655 scopus 로고    scopus 로고
    • Elevated body fat percentage and cardiovascular risks at low body mass index levels among Singaporean Chinese, Malays and Indians
    • Deurenberg-Yap M, Chew SK, Deurenberg P,. Elevated body fat percentage and cardiovascular risks at low body mass index levels among Singaporean Chinese, Malays and Indians. Obes Rev 2002; 3: 209-215.
    • (2002) Obes Rev , vol.3 , pp. 209-215
    • Deurenberg-Yap, M.1    Chew, S.K.2    Deurenberg, P.3
  • 18
    • 41549129937 scopus 로고    scopus 로고
    • Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample
    • Al-Attar SA, Pollex RL, Ban MR, et al. Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample. Cardiovasc Diabetol 2008; 7: 5.
    • (2008) Cardiovasc Diabetol , vol.7 , pp. 5
    • Al-Attar, S.A.1    Pollex, R.L.2    Ban, M.R.3
  • 19
    • 44349166252 scopus 로고    scopus 로고
    • Common genetic variation near MC4R is associated with waist circumference and insulin resistance
    • Chambers JC, Elliott P, Zabaneh D, et al. Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet 2008; 40: 716-718.
    • (2008) Nat Genet , vol.40 , pp. 716-718
    • Chambers, J.C.1    Elliott, P.2    Zabaneh, D.3
  • 20
    • 84856714312 scopus 로고    scopus 로고
    • Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs
    • Gupta V, Vinay DG, Rafiq S, et al. Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs. Diabetologia 2012; 55: 349-357.
    • (2012) Diabetologia , vol.55 , pp. 349-357
    • Gupta, V.1    Vinay, D.G.2    Rafiq, S.3
  • 21
    • 68949123244 scopus 로고    scopus 로고
    • Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management
    • Misra A, Chowbey P, Makkar BM, et al. Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. J Assoc Phys India 2009; 57: 163-170.
    • (2009) J Assoc Phys India , vol.57 , pp. 163-170
    • Misra, A.1    Chowbey, P.2    Makkar, B.M.3
  • 22
    • 80054963552 scopus 로고    scopus 로고
    • Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population
    • Prakash J, Srivastava N, Awasthi S, et al. Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population. Annals Human Biol 2011; 38: 760-763.
    • (2011) Annals Human Biol , vol.38 , pp. 760-763
    • Prakash, J.1    Srivastava, N.2    Awasthi, S.3
  • 23
    • 55849104388 scopus 로고    scopus 로고
    • FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
    • Tan JT, Dorajoo R, Seielstad M, et al. FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes 2008; 57: 2851-2857.
    • (2008) Diabetes , vol.57 , pp. 2851-2857
    • Tan, J.T.1    Dorajoo, R.2    Seielstad, M.3
  • 24
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W,. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 25
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG,. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 26
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • Duval S, Tweedie R,. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000; 56: 455-463.
    • (2000) Biometrics , vol.56 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 27
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C,. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 28
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
    • Purcell S, Cherny SS, Sham PC,. Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149-150.
    • (2003) Bioinformatics , vol.19 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 29
    • 84855705730 scopus 로고    scopus 로고
    • Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations
    • Dorajoo R, Blakemore AI, Sim X, et al. Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations. Int J Obes 2012; 36: 159-163.
    • (2012) Int J Obes , vol.36 , pp. 159-163
    • Dorajoo, R.1    Blakemore, A.I.2    Sim, X.3
  • 30
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40: 768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3
  • 31
    • 35548952185 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide linkage studies in BMI and obesity
    • Saunders CL, Chiodini BD, Sham P, et al. Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) 2007; 15: 2263-2275.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2263-2275
    • Saunders, C.L.1    Chiodini, B.D.2    Sham, P.3
  • 32
    • 67651236725 scopus 로고    scopus 로고
    • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
    • Lindgren CM, Heid IM, Randall JC, et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009; 5: e1000508.
    • (2009) PLoS Genet , vol.5
    • Lindgren, C.M.1    Heid, I.M.2    Randall, J.C.3
  • 33
    • 78049349396 scopus 로고    scopus 로고
    • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
    • Heid IM, Jackson AU, Randall JC, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010; 42: 949-960.
    • (2010) Nat Genet , vol.42 , pp. 949-960
    • Heid, I.M.1    Jackson, A.U.2    Randall, J.C.3
  • 34
    • 84862535700 scopus 로고    scopus 로고
    • Is FTO a type 2 diabetes susceptibility gene?
    • 6.
    • Meyre D,. Is FTO a type 2 diabetes susceptibility gene? Diabetologia 2012; 55: 873-87 6.
    • (2012) Diabetologia , vol.55 , pp. 873-887
    • Meyre, D.1
  • 35
    • 84876513251 scopus 로고    scopus 로고
    • The influence of obesity-related single nucleotide polymorphisms on BMI across the Life Course: The PAGE Study
    • (5).
    • Graff M, Gordon-Larsen P, Lim U, et al. The influence of obesity-related single nucleotide polymorphisms on BMI across the Life Course: The PAGE Study. Diabetes 2013; 62 (5): 1763-1767.
    • (2013) Diabetes , vol.62 , pp. 1763-1767
    • Graff, M.1    Gordon-Larsen, P.2    Lim, U.3
  • 36
    • 74049157110 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies: Methodologies, between-study heterogeneity and winner's curse
    • Nakaoka H, Inoue I,. Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse. J Human Genet 2009; 54: 615-623.
    • (2009) J Human Genet , vol.54 , pp. 615-623
    • Nakaoka, H.1    Inoue, I.2
  • 37
    • 79958076981 scopus 로고    scopus 로고
    • FTO gene polymorphisms and obesity risk: A meta-analysis
    • Peng S, Zhu Y, Xu F, Ren X, Li X, Lai M,. FTO gene polymorphisms and obesity risk: a meta-analysis. BMC Med 2011; 9: 71.
    • (2011) BMC Med , vol.9 , pp. 71
    • Peng, S.1    Zhu, Y.2    Xu, F.3    Ren, X.4    Li, X.5    Lai, M.6
  • 38
    • 21444454737 scopus 로고    scopus 로고
    • The strengths and limitations of meta-analyses based on aggregate data
    • Lyman GH, Kuderer NM,. The strengths and limitations of meta-analyses based on aggregate data. BMC Med Res Methodol 2005; 5: 14.
    • (2005) BMC Med Res Methodol , vol.5 , pp. 14
    • Lyman, G.H.1    Kuderer, N.M.2
  • 39
    • 0035990656 scopus 로고    scopus 로고
    • The lifecycle effects of nutrition and body size on adult adiposity, diabetes and cardiovascular disease
    • Yajnik CS,. The lifecycle effects of nutrition and body size on adult adiposity, diabetes and cardiovascular disease. Obes Rev 2002; 3: 217-224.
    • (2002) Obes Rev , vol.3 , pp. 217-224
    • Yajnik, C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.