Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation

British Journal of Cancer

Volumn 110, Issue 5, 2014, Pages 1307-1315

  Murray, D W ^a,b   Didier, S ^b   Chan, A ^b   Paulino, V ^c   Van Aelst, L ^d   Ruggieri, R ^b   Tran, N L ^c   Byrne, A T ^a,e   Symons, M ^b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b Northwell Health   (United States)

^c TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^d Simons Center for Quantitative Biology   (United States)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

C Met; Dock7; Gab1; Glioblastoma; Invasion; Rac1

Indexed keywords

ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR DOCK7; GUANOSINE TRIPHOSPHATASE; MESSENGER RNA; PROTEIN GAB1; RAC PROTEIN; SCATTER FACTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; SULFORHODAMINE B;

ARTICLE; CELL INVASION; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMELLIPODIUM; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING; BRAIN SLICE; COLONY FORMATION; CONTROLLED STUDY; IMMUNOPRECIPITATION; TUMOR INVASION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANGIOGENESIS INHIBITORS; BRAIN NEOPLASMS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; GLIOBLASTOMA; GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEPATOCYTE GROWTH FACTOR; HUMANS; PROTO-ONCOGENE PROTEINS C-MET; RAC1 GTP-BINDING PROTEIN; RHO GTP-BINDING PROTEINS;

EID: 84895782658     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.39     Document Type: Article

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