Regeneration of injured renal tubules

Journal of Pharmacological Sciences

Volumn 124, Issue 2, 2014, Pages 117-122

  Yoshida, Makoto ^a   Honma, Shigeyoshi ^a  

^a TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Acute kidney injury (AKI); Kidney; Regeneration; Tubule

Indexed keywords

CISPLATIN; CREATININE; CYCLOOXYGENASE 2 INHIBITOR; TRANSCRIPTION FACTOR;

ACUTE KIDNEY FAILURE; ANTIINFLAMMATORY ACTIVITY; CELL DEDIFFERENTIATION; CREATININE BLOOD LEVEL; HUMAN; HYPOXIA; IMMUNE RESPONSE; INFLAMMATION; KIDNEY TUBULE DAMAGE; KIDNEY TUBULE NECROSIS; MICTURITION; NONHUMAN; PATHOPHYSIOLOGY; RENAL PROTECTION; REVIEW; STEM CELL TRANSPLANTATION; TISSUE REGENERATION;

ACUTE KIDNEY INJURY; ANTINEOPLASTIC AGENTS; CISPLATIN; DISEASE PROGRESSION; FEMALE; HUMANS; KIDNEY TUBULES; MALE; OXIDATIVE STRESS; RECOVERY OF FUNCTION; REGENERATION; RENAL INSUFFICIENCY, CHRONIC; REPERFUSION INJURY;

EID: 84895560010     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.13R12CP     Document Type: Review

References (35)

1. Song JJ, Guyette JP, Gilpin SE, Gonzalez G, Vacanti JP, Ott HC. Regeneration and experimental orthotopic transplantation of a bioengineered kidney. Nature Med. 2013;19: 646-651.
2. Hartman HA, Lai HL, Patterson LT. Cessation of renal morphogenesis in mice. Dev Biol. 2007;310: 379-387.
3. Group TKDIGO (KDIGO) W. Section 2: AKI Definition. Kidney Int Suppl. 2012;2: 19-36.
4. Bagnasco S, Good D, Balaban R, Burg M. Lactate production in isolated segments of the rat nephron. Am J Physiol. 1985;248:F522-F526.
5. Eltzschig HK, Carmeliet P. Hypoxia and inflammation. N Eng J Med. 2011;364: 656-665.
6. Basile DP. The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. Kidney Int. 2007;72: 151-156.
7. Wu H, Chen G, Wyburn KR, Yin J, Bertolino P, Eris JM, et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest. 2007;117: 2847-2859.
8. Leemans JC, Stokman G, Claessen N, Rouschop KM, Teske GJD, Kirschning CJ, et al. Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest. 2005;115: 2894-2903.
9. Havasi A, Borkan SC. Apoptosis and acute kidney injury. Kidney Int. 2011;80: 29-40.
10. Koeppen M, Eckle T, Eltzschig HK. The hypoxia-inflammation link and potential drug targets. Curr Opin Anaesthesiol. 2011;24: 363-369.
11. Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, et al. Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci U S A. 2006;103: 18154-18159.
12. Kapitsinou PP, Jaffe J, Michael M, Swan CE, Duffy KJ, Erickson-Miller CL, et al. Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury. Am J Physiol. 2012;302:F1172-F1179.
13. Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest. 2011;121: 4210-4221.
14. Kelly KJ, Williams WW, Colvin RB, Meehan SM, Springer TA, Gutierrez-Ramos JC, et al. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest. 1996;97: 1056-1063.
15. Kawai Y, Satoh T, Hibi D, Ohno Y, Kohda Y, Miura K, et al. The effect of antioxidant on development of fibrosis by cisplatin in rats. J Pharmacol Sci. 2009;111: 433-439.
16. Mitazaki S, Honma S, Suto M, Kato N, Hiraiwa K, Yoshida M, et al. Interleukin-6 plays a protective role in development of cisplatin-induced acute renal failure through upregulation of anti-oxidative stress factors. Life Sci. 2011;88: 1142-1148.
17. Honma S, Takahashi N, Shinohara M, Nakamura K, Mitazaki S, Abe S, et al. Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. Eur J Pharmacol. 2013;715: 181-188.
18. Luo J, Tsuji T, Yasuda H, Sun Y, Fujigaki Y, Hishida A. The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats. Nephrol Dialys Transplantat. 2008;23: 2198-2205.
19. Maeshima A, Yamashita S, Nojima Y. Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. J Am Soc Nephrol. 2003;14: 3138-3146.
20. Maeshima A, Sakurai H, Nigam SK. Adult kidney tubular cell population showing phenotypic plasticity, tubulogenic capacity, and integration capability into developing kidney. J Am Soc Nephrol. 2006;17: 188-198.
21. Nadasdy T, Laszik Z, Blick KE, Johnson DL, Burst-Singer K, Nast C, et al. Human acute tubular necrosis: a lectin and immunohistochemical study. Human Pathol. 1995;26: 230-239.
22. Oliver JA, Maarouf O, Cheema FH, Martens TP, Al-Awqati Q. The renal papilla is a niche for adult kidney stem cells. J Clin Invest. 2004;114: 795-804.
23. Oliver JA, Klinakis A, Cheema FH, Friedlander J, Sampogna RV, Martens TP, et al. Proliferation and migration of label-retaining cells of the kidney papilla. J Am Soc Nephrol. 2009;20: 2315-2327.
24. Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008;2: 284-291.
25. Kitamura S, Yamasaki Y, Kinomura M, Sugaya T, Sugiyama H, Maeshima Y, et al. Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney. FASEB J. 2005;19: 1789-1797.
26. Langworthy M, Zhou B, de Caestecker M, Moeckel G, Baldwin HS. NFATc1 identifies a population of proximal tubule cell progenitors. J Am Soc Nephrol. 2009;20: 311-321.
27. Lindgren D, Boström A-K, Nilsson K, Hansson J, Sjölund J, Möller C, et al. Isolation and characterization of progenitor-like cells from human renal proximal tubules. Am J Pathol. 2011;178: 828-837.
28. Angelotti ML, Ronconi E, Ballerini L, Peired A, Mazzinghi B, Sagrinati C, et al. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells. 2012;30: 1714-1725.
29. Kriz W, Kaissling B, Le Hir M. Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? J Clin Invest. 2011;121: 468-474.
30. Humphreys BD, Czerniak S, DiRocco DP, Hasnain W, Cheema R, Bonventre JV. Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A. 2011;108: 9226-9231.
31. Poulsom R, Forbes SJ, Hodivala-Dilke K, Ryan E, Wyles S, Navaratnarasah S, et al. Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol. 2001;195: 229-235.
32. Gupta S, Verfaillie C, Chmielewski D, Kim Y, Rosenberg ME. A role for extrarenal cells in the regeneration following acute renal failure. Kidney Int. 2002;62: 1285-1290.
33. Lin F, Cordes K, Li L, Hood L, Couser WG, Shankland SJ, et al. Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol. 2003;14: 1188-1199.
34. Bi B, Schmitt R, Israilova M, Nishio H, Cantley LG. Stromal cells protect against acute tubular injury via an endocrine effect. J Am Soc Nephrol. 2007;18: 2486-2496.
35. El Sabbahy M, Vaidya VS. Ischemic kidney injury and mechanisms of tissue repair. Wiley Interdiscip Rev Syst Biol Med. 2011;3: 606-618.