Steroid resistance in COPD? overlap and differential anti-inflammatory effects in smokers and ex-smokers

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Hoonhorst, Susan J M ^a   Ten Hacken, Nick H T ^a   Vonk, Judith M ^a   Timens, Wim ^a   Hiemstra, Pieter S ^b   Lapperre, Thér̀ese S ^b   Sterk, Peter J ^c   Postma, Dirkje S ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; FLUTICASONE PROPIONATE; PLACEBO; SALMETEROL;

ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHUS BIOPSY; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL (TOPIC); COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATIONAL STUDY; EX SMOKER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATORY CELL; LONG TERM CARE; LUNG FUNCTION; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MAST CELL; NAMED GROUPS OF PERSONS; NEUTROPHIL; OUTCOMES RESEARCH; POST HOC ANALYSIS; RESPIRATORY TRACT ALLERGY; SHORT COURSE THERAPY; SMOKING; SPUTUM CULTURE; TREATMENT DURATION;

ADRENAL CORTEX HORMONES; AGED; DRUG RESISTANCE; FEMALE; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; SMOKING CESSATION; TIME FACTORS;

EID: 84895559489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087443     Document Type: Article

References (22)

1. Global initiative for Chronic Obstructive Lung Disease (2010) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease.
2. Willemse BW, ten Hacken NH, Rutgers B, Lesman-Leegte IG, Postma DS, et al. (2005) Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers. Eur Respir J 26: 835-845. (Pubitemid 41632040)
3. Lapperre TS, Postma DS, Gosman MM, Snoeck-Stroband JB, ten Hacken NH, et al. (2006) Relation between duration of smoking cessation and bronchial inflammation in COPD. Thorax 61: 115-121. (Pubitemid 43235427)
4. Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA, et al. (2000) Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial. BMJ 320: 1297-1303. (Pubitemid 30245717)
5. Celli BR, Thomas NE, Anderson JA, Ferguson GT, Jenkins CR, et al. (2008) Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: Results from the TORCH study. Am J Respir Crit Care Med 178: 332-338.
6. Calverley P, Pauwels R, Vestbo J, Jones P, Pride N, et al. (2003) Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: A randomised controlled trial. Lancet 361: 449-456. (Pubitemid 36173708)
7. Suissa S, Patenaude V, Lapi F, Ernst P (2013) Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax 68: 1029-1036.
8. Lapperre TS, Snoeck-Stroband JB, Gosman MM, Jansen DF, van Schadewijk A, et al. (2009) Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: A randomized trial. Ann Intern Med 151: 517-527.
9. Culpitt SV, Maziak W, Loukidis S, Nightingale JA, Matthews JL, et al. (1999) Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160: 1635-1639.
10. Hattotuwa KL, Gizycki MJ, Ansari TW, Jeffery PK, Barnes NC (2002) The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: A double-blind, placebo-controlled biopsy study. Am J Respir Crit Care Med 165: 1592-1596. (Pubitemid 34693937)
11. Bourbeau J, Christodoulopoulos P, Maltais F, Yamauchi Y, Olivenstein R, et al. (2007) Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: A randomised controlled trial. Thorax 62: 938-943. (Pubitemid 350084490)
12. Barnes NC, Qiu YS, Pavord ID, Parker D, Davis PA, et al. (2006) Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease. Am J Respir Crit Care Med 173: 736-743.
13. Chalmers GW, Macleod KJ, Little SA, Thomson LJ, McSharry CP, et al. (2002) Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma. Thorax 57: 226-230. (Pubitemid 34214408)
14. Chaudhuri R, Livingston E, McMahon AD, Thomson L, Borland W, et al. (2003) Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma. Am J Respir Crit Care Med 168: 1308-1311. (Pubitemid 37487324)
15. Tomlinson JE, McMahon AD, Chaudhuri R, Thompson JM, Wood SF, et al. (2005) Efficacy of low and high dose inhaled corticosteroid in smokers versus non-smokers with mild asthma. Thorax 60: 282-287. (Pubitemid 40522363)
16. Van Overveld FJ, Demkow U, Gorecka D, De Backer WA, Zielinski J (2006) Differences in responses upon corticosteroid therapy between smoking and non-smoking patients with COPD. J Physiol Pharmacol 57 Suppl 4: 273-282. (Pubitemid 44638210)
17. Barnes PJ (2010) Mechanisms and resistance in glucocorticoid control of inflammation. J Steroid Biochem Mol Biol 120: 76-85.
18. Ito K, Ito M, Elliott WM, Cosio B, Caramori G, et al. (2005) Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 352: 1967-1976. (Pubitemid 40638367)
19. Lapperre TS, Snoeck-Stroband JB, Gosman MM, Stolk J, Sont JK, et al. (2004) Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 170: 499-504. (Pubitemid 39209130)
20. Yang Y, Haitchi HM, Cakebread J, Sammut D, Harvey A, et al. (2008) Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. J Allergy Clin Immunol 121: 1393-9, 1399.e1-14.
21. Gizycki MJ, Hattotuwa KL, Barnes N, Jeffery PK (2002) Effects of fluticasone propionate on inflammatory cells in COPD: An ultrastructural examination of endobronchial biopsy tissue. Thorax 57: 799-803. (Pubitemid 34984979)
22. Kaur M, Smyth LJ, Cadden P, Grundy S, Ray D, et al. (2012) T lymphocyte insensitivity to corticosteroids in chronic obstructive pulmonary disease. Respir Res 13: 20.