-
1
-
-
2542486456
-
Asthma: Mechanisms of disease persistence and progression
-
L. Cohn, J.A. Elias, and G.L. Chupp Asthma: mechanisms of disease persistence and progression Annu Rev Immunol 22 2004 789 815
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 789-815
-
-
Cohn, L.1
Elias, J.A.2
Chupp, G.L.3
-
2
-
-
2542428442
-
Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells
-
A. Rot, and U.H. von Andrian Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells Annu Rev Immunol 22 2004 891 928
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 891-928
-
-
Rot, A.1
Von Andrian, U.H.2
-
3
-
-
34247855761
-
Chemokine: Receptor structure, interactions, and antagonism
-
S.J. Allen, S.E. Crown, and T.M. Handel Chemokine: receptor structure, interactions, and antagonism Annu Rev Immunol 25 2007 787 820
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 787-820
-
-
Allen, S.J.1
Crown, S.E.2
Handel, T.M.3
-
4
-
-
0033485409
-
Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics
-
S. Ying, Q. Meng, K. Zeibecoglou, D.S. Robinson, and A. Macfarlane et al. Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics J Immunol 163 1999 6321 6329
-
(1999)
J Immunol
, vol.163
, pp. 6321-6329
-
-
Ying, S.1
Meng, Q.2
Zeibecoglou, K.3
Robinson, D.S.4
Macfarlane, A.5
-
6
-
-
0029944290
-
Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia
-
E.A. Garcia-Zepeda, M.E. Rothenberg, R.T. Ownbey, J. Celestin, and P. Leder et al. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia Nat Med 2 1996 449 456
-
(1996)
Nat Med
, vol.2
, pp. 449-456
-
-
Garcia-Zepeda, E.A.1
Rothenberg, M.E.2
Ownbey, R.T.3
Celestin, J.4
Leder, P.5
-
7
-
-
0030702124
-
Role of the monocyte chemoattractant protein and eotaxin subfamily of chemokines in allergic inflammation
-
A.D. Luster, and M.E. Rothenberg Role of the monocyte chemoattractant protein and eotaxin subfamily of chemokines in allergic inflammation J Leukoc Biol 62 1997 620 633
-
(1997)
J Leukoc Biol
, vol.62
, pp. 620-633
-
-
Luster, A.D.1
Rothenberg, M.E.2
-
8
-
-
2642705856
-
Detection of MCP-4 in dermal fibroblasts and its activation of the respiratory burst in human eosinophils
-
H. Petering, R. Hochstetter, D. Kimmig, R. Smolarski, and A. Kapp et al. Detection of MCP-4 in dermal fibroblasts and its activation of the respiratory burst in human eosinophils J Immunol 160 1998 555 558
-
(1998)
J Immunol
, vol.160
, pp. 555-558
-
-
Petering, H.1
Hochstetter, R.2
Kimmig, D.3
Smolarski, R.4
Kapp, A.5
-
9
-
-
0035198986
-
IL-4 differentially regulates eotaxin and MCP-4 in lung epithelium and circulating mononuclear cells
-
H. Nakamura, A.D. Luster, H. Tateno, S. Jedrzkiewicz, and G. Tamura et al. IL-4 differentially regulates eotaxin and MCP-4 in lung epithelium and circulating mononuclear cells Am J Physiol Lung Cell Mol Physiol 281 2001 L1288 L1302
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.281
-
-
Nakamura, H.1
Luster, A.D.2
Tateno, H.3
Jedrzkiewicz, S.4
Tamura, G.5
-
10
-
-
0031558766
-
The monocyte chemotactic protein-4 induces oxygen radical production, actin reorganization, and CD11b up-regulation via a pertussis toxin-sensitive G-protein in human eosinophils
-
K. Tenscher, B. Metzner, C. Hofmann, E. Schopf, and J. Norgauer The monocyte chemotactic protein-4 induces oxygen radical production, actin reorganization, and CD11b up-regulation via a pertussis toxin-sensitive G-protein in human eosinophils Biochem Biophys Res Commun 240 1997 32 35
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 32-35
-
-
Tenscher, K.1
Metzner, B.2
Hofmann, C.3
Schopf, E.4
Norgauer, J.5
-
11
-
-
0037103183
-
Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo
-
G.A. McQuibban, J.H. Gong, J.P. Wong, J.L. Wallace, and I. Clark-Lewis et al. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo Blood 100 2002 1160 1167
-
(2002)
Blood
, vol.100
, pp. 1160-1167
-
-
McQuibban, G.A.1
Gong, J.H.2
Wong, J.P.3
Wallace, J.L.4
Clark-Lewis, I.5
-
12
-
-
54049106148
-
Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR + CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: Potential role of the macrophage in terminating polymorphonuclear leukocyte influx
-
R.A. Dean, J.H. Cox, C.L. Bellac, A. Doucet, and A.E. Starr et al. Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR + CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx Blood 112 2008 3455 3464
-
(2008)
Blood
, vol.112
, pp. 3455-3464
-
-
Dean, R.A.1
Cox, J.H.2
Bellac, C.L.3
Doucet, A.4
Starr, A.E.5
-
13
-
-
77950929777
-
Proteolytic cleavage of chemokines by Trypanosoma cruzi's cruzipain inhibits chemokine functions by promoting the generation of antagonists
-
I. Benitez-Hernandez, E. Mendez-Enriquez, P. Ostoa, T. Fortoul, and J.A. Ramirez et al. Proteolytic cleavage of chemokines by Trypanosoma cruzi's cruzipain inhibits chemokine functions by promoting the generation of antagonists Immunobiology 215 2010 413 426
-
(2010)
Immunobiology
, vol.215
, pp. 413-426
-
-
Benitez-Hernandez, I.1
Mendez-Enriquez, E.2
Ostoa, P.3
Fortoul, T.4
Ramirez, J.A.5
-
14
-
-
42049113651
-
CDIP-2, a synthetic peptide derived from chemokine (C-C motif) ligand 13 (CCL13), ameliorates allergic airway inflammation
-
E. Mendez-Enriquez, Y. Melendez, F. Martinez, G. Baay, and S. Huerta-Yepez et al. CDIP-2, a synthetic peptide derived from chemokine (C-C motif) ligand 13 (CCL13), ameliorates allergic airway inflammation Clin Exp Immunol 152 2008 354 363
-
(2008)
Clin Exp Immunol
, vol.152
, pp. 354-363
-
-
Mendez-Enriquez, E.1
Melendez, Y.2
Martinez, F.3
Baay, G.4
Huerta-Yepez, S.5
-
15
-
-
56149088519
-
Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow
-
K.D. Dyer, J.M. Moser, M. Czapiga, S.J. Siegel, C.M. Percopo, and H.F. Rosenberg Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow J Immunol 181 2008 4004 4009
-
(2008)
J Immunol
, vol.181
, pp. 4004-4009
-
-
Dyer, K.D.1
Moser, J.M.2
Czapiga, M.3
Siegel, S.J.4
Percopo, C.M.5
Rosenberg, H.F.6
-
16
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method
-
K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method Methods 25 2001 402 408
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
17
-
-
2942724339
-
Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells
-
T. Adachi, C.H. Cui, A. Kanda, H. Kayaba, and K. Ohta et al. Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells Biochem Biophys Res Commun 320 2004 292 296
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 292-296
-
-
Adachi, T.1
Cui, C.H.2
Kanda, A.3
Kayaba, H.4
Ohta, K.5
-
18
-
-
0030669468
-
Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils
-
J.R. White, C. Imburgia, E. Dul, E. Appelbaum, and K. O'Donnell et al. Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils J Leukoc Biol 62 1997 667 675
-
(1997)
J Leukoc Biol
, vol.62
, pp. 667-675
-
-
White, J.R.1
Imburgia, C.2
Dul, E.3
Appelbaum, E.4
O'Donnell, K.5
-
19
-
-
34249798763
-
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling
-
P.C. Fulkerson, C.A. Fischetti, and M.E. Rothenberg Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling Am J Pathol 169 2006 2117 2126
-
(2006)
Am J Pathol
, vol.169
, pp. 2117-2126
-
-
Fulkerson, P.C.1
Fischetti, C.A.2
Rothenberg, M.E.3
-
20
-
-
79251577990
-
Targeting chemokine receptors in allergic disease
-
J.E. Pease Targeting chemokine receptors in allergic disease Biochem J 434 2011 11 24
-
(2011)
Biochem J
, vol.434
, pp. 11-24
-
-
Pease, J.E.1
-
21
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
B. Wu, E.Y. Chien, C.D. Mol, G. Fenalti, and W. Liu et al. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science 330 2010 1066 1071
-
(2010)
Science
, vol.330
, pp. 1066-1071
-
-
Wu, B.1
Chien, E.Y.2
Mol, C.D.3
Fenalti, G.4
Liu, W.5
-
22
-
-
34948844197
-
Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation
-
E.L. Wise, C. Duchesnes, P.C. da Fonseca, R.A. Allen, T.J. Williams, and J.E. Pease Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation J Biol Chem 282 2007 27935 27943
-
(2007)
J Biol Chem
, vol.282
, pp. 27935-27943
-
-
Wise, E.L.1
Duchesnes, C.2
Da Fonseca, P.C.3
Allen, R.A.4
Williams, T.J.5
Pease, J.E.6
-
23
-
-
17444366208
-
The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down-regulation in a ligand-dependent manner
-
I. Sabroe, A. Jorritsma, V.E. Stubbs, G. Xanthou, and L.A. Jopling et al. The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down-regulation in a ligand-dependent manner Eur J Immunol 35 2005 1301 1310
-
(2005)
Eur J Immunol
, vol.35
, pp. 1301-1310
-
-
Sabroe, I.1
Jorritsma, A.2
Stubbs, V.E.3
Xanthou, G.4
Jopling, L.A.5
-
24
-
-
79952131553
-
Tyrosine sulfation influences the chemokine binding selectivity of peptides derived from chemokine receptor CCR3
-
J.Z. Zhu, C.J. Millard, J.P. Ludeman, L.S. Simpson, and D.J. Clayton et al. Tyrosine sulfation influences the chemokine binding selectivity of peptides derived from chemokine receptor CCR3 Biochemistry 50 2011 1524 1534
-
(2011)
Biochemistry
, vol.50
, pp. 1524-1534
-
-
Zhu, J.Z.1
Millard, C.J.2
Ludeman, J.P.3
Simpson, L.S.4
Clayton, D.J.5
-
25
-
-
43049107148
-
Proteolytic processing of chemokines: Implications in physiological and pathological conditions
-
M. Wolf, S. Albrecht, and C. Marki Proteolytic processing of chemokines: implications in physiological and pathological conditions Int J Biochem Cell Biol 40 2008 1185 1198
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1185-1198
-
-
Wolf, M.1
Albrecht, S.2
Marki, C.3
-
26
-
-
0035958068
-
Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin
-
M.R. Mayer, and M.J. Stone Identification of receptor binding and activation determinants in the N-terminal and N-loop regions of the CC chemokine eotaxin J Biol Chem 276 2001 13911 13916
-
(2001)
J Biol Chem
, vol.276
, pp. 13911-13916
-
-
Mayer, M.R.1
Stone, M.J.2
-
27
-
-
0034714211
-
A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry
-
I. Sabroe, M.J. Peck, B.J. Van Keulen, A. Jorritsma, and G. Simmons et al. A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry J Biol Chem 275 2000 25985 25992
-
(2000)
J Biol Chem
, vol.275
, pp. 25985-25992
-
-
Sabroe, I.1
Peck, M.J.2
Van Keulen, B.J.3
Jorritsma, A.4
Simmons, G.5
-
29
-
-
30544433445
-
Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice
-
K.J. Carpenter, J.L. Ewing, J.M. Schuh, T.L. Ness, and S.L. Kunkel et al. Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice Br J Pharmacol 145 2005 1160 1172
-
(2005)
Br J Pharmacol
, vol.145
, pp. 1160-1172
-
-
Carpenter, K.J.1
Ewing, J.L.2
Schuh, J.M.3
Ness, T.L.4
Kunkel, S.L.5
-
30
-
-
0030589313
-
Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3
-
E.A. Garcia-Zepeda, C. Combadiere, M.E. Rothenberg, M.N. Sarafi, and F. Lavigne et al. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3 J Immunol 157 1996 5613 5626
-
(1996)
J Immunol
, vol.157
, pp. 5613-5626
-
-
Garcia-Zepeda, E.A.1
Combadiere, C.2
Rothenberg, M.E.3
Sarafi, M.N.4
Lavigne, F.5
-
31
-
-
0035313370
-
Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5
-
P. Ogilvie, G. Bardi, I. Clark-Lewis, M. Baggiolini, and M. Uguccioni Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5 Blood 97 2001 1920 1924
-
(2001)
Blood
, vol.97
, pp. 1920-1924
-
-
Ogilvie, P.1
Bardi, G.2
Clark-Lewis, I.3
Baggiolini, M.4
Uguccioni, M.5
-
32
-
-
53749083136
-
Regulation of chemokine activity by posttranslational modification
-
A. Mortier, J. Van Damme, and P. Proost Regulation of chemokine activity by posttranslational modification Pharmacol Ther 120 2008 197 217
-
(2008)
Pharmacol Ther
, vol.120
, pp. 197-217
-
-
Mortier, A.1
Van Damme, J.2
Proost, P.3
-
33
-
-
34347373032
-
Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma
-
B. Lagu, C. Gerchak, M. Pan, C. Hou, and M. Singer et al. Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma Bioorg Med Chem Lett 17 2007 4382 4386
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 4382-4386
-
-
Lagu, B.1
Gerchak, C.2
Pan, M.3
Hou, C.4
Singer, M.5
-
35
-
-
0032833999
-
Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2
-
S. Hemmerich, C. Paavola, A. Bloom, S. Bhakta, and R. Freedman et al. Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2 Biochemistry 38 1999 13013 13025
-
(1999)
Biochemistry
, vol.38
, pp. 13013-13025
-
-
Hemmerich, S.1
Paavola, C.2
Bloom, A.3
Bhakta, S.4
Freedman, R.5
-
36
-
-
0035900753
-
The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b
-
R. Martinelli, I. Sabroe, G. LaRosa, T.J. Williams, and J.E. Pease The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b J Biol Chem 276 2001 42957 42964
-
(2001)
J Biol Chem
, vol.276
, pp. 42957-42964
-
-
Martinelli, R.1
Sabroe, I.2
Larosa, G.3
Williams, T.J.4
Pease, J.E.5
-
37
-
-
2442644001
-
Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway
-
P. Ogilvie, S. Thelen, B. Moepps, P. Gierschik, and A.C. da Silva Campos et al. Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway J Immunol 172 2004 6715 6722
-
(2004)
J Immunol
, vol.172
, pp. 6715-6722
-
-
Ogilvie, P.1
Thelen, S.2
Moepps, B.3
Gierschik, P.4
Da Silva Campos, A.C.5
-
38
-
-
2942635467
-
High level expression, activation, and antagonism of CC chemokine receptors CCR2 and CCR3 in Chinese hamster ovary cells
-
T.R. Parody, and M.J. Stone High level expression, activation, and antagonism of CC chemokine receptors CCR2 and CCR3 in Chinese hamster ovary cells Cytokine 27 2004 38 46
-
(2004)
Cytokine
, vol.27
, pp. 38-46
-
-
Parody, T.R.1
Stone, M.J.2
-
39
-
-
13844274981
-
Cytokine-stimulated human lung alveolar epithelial cells release eotaxin-2 (CCL24) and eotaxin-3 (CCL26)
-
A.S. Heiman, B.O. Abonyo, S.F. Darling-Reed, and M.S. Alexander Cytokine-stimulated human lung alveolar epithelial cells release eotaxin-2 (CCL24) and eotaxin-3 (CCL26) J Interferon Cytokine Res 25 2005 82 91
-
(2005)
J Interferon Cytokine Res
, vol.25
, pp. 82-91
-
-
Heiman, A.S.1
Abonyo, B.O.2
Darling-Reed, S.F.3
Alexander, M.S.4
-
40
-
-
50149096186
-
Role and pharmacogenomics of TNF-alpha in asthma
-
D. Lykouras, F. Sampsonas, A. Kaparianos, K. Karkoulias, and K. Spiropoulos Role and pharmacogenomics of TNF-alpha in asthma Mini Rev Med Chem 8 2008 934 942
-
(2008)
Mini Rev Med Chem
, vol.8
, pp. 934-942
-
-
Lykouras, D.1
Sampsonas, F.2
Kaparianos, A.3
Karkoulias, K.4
Spiropoulos, K.5
|