-
1
-
-
77955472579
-
Evolving challenges in hepatic fibrosis
-
Friedman SL. Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol 2010; 7:425-436.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 425-436
-
-
Friedman, S.L.1
-
2
-
-
0027243462
-
Risk factors for hepatocellular carcinoma among patients with chronic liver disease
-
Tsukuma H, Hiyama T, Tanaka S etal. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993; 328:1797-1801.
-
(1993)
N Engl J Med
, vol.328
, pp. 1797-1801
-
-
Tsukuma, H.1
Hiyama, T.2
Tanaka, S.3
-
3
-
-
1242284968
-
Prevention and treatment of hepatocellular carcinoma
-
Omata M, Yoshida H. Prevention and treatment of hepatocellular carcinoma. Liver Transpl 2004; 10:S111-114.
-
(2004)
Liver Transpl
, vol.10
-
-
Omata, M.1
Yoshida, H.2
-
4
-
-
0030707941
-
Hepatitis B virus infection
-
Lee WM. Hepatitis B virus infection. N Engl J Med 1997; 337:1733-1745.
-
(1997)
N Engl J Med
, vol.337
, pp. 1733-1745
-
-
Lee, W.M.1
-
5
-
-
84859553856
-
The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients
-
Jiang ZS, Jhunjhunwala S, Liu JF etal. The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients. Genome Res 2012; 22:593-601.
-
(2012)
Genome Res
, vol.22
, pp. 593-601
-
-
Jiang, Z.S.1
Jhunjhunwala, S.2
Liu, J.F.3
-
6
-
-
0025907983
-
HBx gene of hepatitis B virus induces liver cancer in transgenic mice
-
Kim CM, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991; 351:317-320.
-
(1991)
Nature
, vol.351
, pp. 317-320
-
-
Kim, C.M.1
Koike, K.2
Saito, I.3
Miyamura, T.4
Jay, G.5
-
7
-
-
0033058294
-
Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein
-
Yu DY, Moon HB, Son JK etal. Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein. J Hepatol 1999; 31:123-132.
-
(1999)
J Hepatol
, vol.31
, pp. 123-132
-
-
Yu, D.Y.1
Moon, H.B.2
Son, J.K.3
-
8
-
-
0028230728
-
High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice
-
Koike K, Moriya K, Iino S etal. High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice. Hepatology 1994; 19:810-819.
-
(1994)
Hepatology
, vol.19
, pp. 810-819
-
-
Koike, K.1
Moriya, K.2
Iino, S.3
-
9
-
-
0033592764
-
Lamivudine as initial treatment for chronic hepatitis B in the United States
-
Dienstag JL, Schiff ER, Wright TL etal. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med 1999; 341:1256-1263.
-
(1999)
N Engl J Med
, vol.341
, pp. 1256-1263
-
-
Dienstag, J.L.1
Schiff, E.R.2
Wright, T.L.3
-
10
-
-
0037468421
-
Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
-
Marcellin P, Chang TT, Lim SG etal. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003; 348:808-816.
-
(2003)
N Engl J Med
, vol.348
, pp. 808-816
-
-
Marcellin, P.1
Chang, T.T.2
Lim, S.G.3
-
11
-
-
33644818518
-
A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
-
Chang TT, Gish RG, de Man R etal. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006; 354:1001-1010.
-
(2006)
N Engl J Med
, vol.354
, pp. 1001-1010
-
-
Chang, T.T.1
Gish, R.G.2
de Man, R.3
-
12
-
-
37349120537
-
Telbivudine versus lamivudine in patients with chronic hepatitis B
-
Lai CL, Gane E, Liaw YF etal. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med 2007; 357:2576-2588.
-
(2007)
N Engl J Med
, vol.357
, pp. 2576-2588
-
-
Lai, C.L.1
Gane, E.2
Liaw, Y.F.3
-
13
-
-
0028130055
-
Inhibitory effects of acyclic nucleoside phosphonates on human hepatitis B virus and duck hepatitis B virus infections in tissue culture
-
Heijtink RA, Kruining J, de Wilde GA, Balzarini J, de Clercq E, Schalm SW. Inhibitory effects of acyclic nucleoside phosphonates on human hepatitis B virus and duck hepatitis B virus infections in tissue culture. Antimicrob Agents Chemother 1994; 38:2180-2182.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2180-2182
-
-
Heijtink, R.A.1
Kruining, J.2
de Wilde, G.A.3
Balzarini, J.4
de Clercq, E.5
Schalm, S.W.6
-
15
-
-
21244455293
-
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ etal. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med 2005; 352:2673-2681.
-
(2005)
N Engl J Med
, vol.352
, pp. 2673-2681
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
16
-
-
19544391413
-
Lamivudine for patients with chronic hepatitis B and advanced liver disease
-
Liaw YF, Sung JJ, Chow WC etal. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 2004; 351:1521-1531.
-
(2004)
N Engl J Med
, vol.351
, pp. 1521-1531
-
-
Liaw, Y.F.1
Sung, J.J.2
Chow, W.C.3
-
17
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390:465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
ten Dijke, P.3
-
18
-
-
0034695511
-
Regulation of Smad activity
-
Wrana JL. Regulation of Smad activity. Cell 2000; 100:189-192.
-
(2000)
Cell
, vol.100
, pp. 189-192
-
-
Wrana, J.L.1
-
19
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003; 113:685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
20
-
-
23044466047
-
Specificity and versatility in TGF-beta signaling through Smads
-
Feng XH, Derynck R. Specificity and versatility in TGF-beta signaling through Smads. Annu Rev Cell Dev Biol 2005; 21:659-693.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
21
-
-
58149216052
-
Signaling cross-talk between TGF-beta/BMP and other pathways
-
Guo X, Wang XF. Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res 2009; 19:71-88.
-
(2009)
Cell Res
, vol.19
, pp. 71-88
-
-
Guo, X.1
Wang, X.F.2
-
22
-
-
0141866937
-
p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts
-
Furukawa F, Matsuzaki K, Mori S etal. p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts. Hepatology 2003; 38:879-889.
-
(2003)
Hepatology
, vol.38
, pp. 879-889
-
-
Furukawa, F.1
Matsuzaki, K.2
Mori, S.3
-
23
-
-
6044261233
-
TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions
-
Mori S, Matsuzaki K, Yoshida K etal. TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions. Oncogene 2004; 23:7416-7429.
-
(2004)
Oncogene
, vol.23
, pp. 7416-7429
-
-
Mori, S.1
Matsuzaki, K.2
Yoshida, K.3
-
24
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
Matsuura I, Denissova NG, Wang G, He D, Long J, Liu F. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 2004; 430:226-231.
-
(2004)
Nature
, vol.430
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
25
-
-
34347232205
-
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma
-
Matsuzaki K, Murata M, Yoshida K etal. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. Hepatology 2007; 46:48-57.
-
(2007)
Hepatology
, vol.46
, pp. 48-57
-
-
Matsuzaki, K.1
Murata, M.2
Yoshida, K.3
-
26
-
-
65449159717
-
Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B
-
Murata M, Matsuzaki K, Yoshida K etal. Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B. Hepatology 2009; 49:1203-1217.
-
(2009)
Hepatology
, vol.49
, pp. 1203-1217
-
-
Murata, M.1
Matsuzaki, K.2
Yoshida, K.3
-
27
-
-
67650377329
-
Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor-suppression in rat hepatocellular carcinoma
-
Nagata H, Hatano E, Tada M etal. Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor-suppression in rat hepatocellular carcinoma. Hepatology 2009; 49:1944-1953.
-
(2009)
Hepatology
, vol.49
, pp. 1944-1953
-
-
Nagata, H.1
Hatano, E.2
Tada, M.3
-
28
-
-
20244376914
-
Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury
-
Yoshida K, Matsuzaki K, Mori S etal. Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury. Am J Pathol 2005; 166:1029-1039.
-
(2005)
Am J Pathol
, vol.166
, pp. 1029-1039
-
-
Yoshida, K.1
Matsuzaki, K.2
Mori, S.3
-
29
-
-
0028235641
-
Classification of chronic hepatitis: diagnosis, grading and staging
-
Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19:1513-1520.
-
(1994)
Hepatology
, vol.19
, pp. 1513-1520
-
-
Desmet, V.J.1
Gerber, M.2
Hoofnagle, J.H.3
Manns, M.4
Scheuer, P.J.5
-
30
-
-
34347235524
-
Reversible Smad-dependent signaling between tumor suppression and oncogenesis
-
Sekimoto G, Matsuzaki K, Yoshida K etal. Reversible Smad-dependent signaling between tumor suppression and oncogenesis. Cancer Res 2007; 67:5090-5096.
-
(2007)
Cancer Res
, vol.67
, pp. 5090-5096
-
-
Sekimoto, G.1
Matsuzaki, K.2
Yoshida, K.3
-
31
-
-
70350569308
-
Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination
-
Liang X, Bi S, Yang W etal. Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination. Vaccine 2009; 27:6550-6557.
-
(2009)
Vaccine
, vol.27
, pp. 6550-6557
-
-
Liang, X.1
Bi, S.2
Yang, W.3
-
32
-
-
0021751383
-
Survival in chronic hepatitis B. An analysis of 379 patients
-
Weissberg JI, Andres LL, Smith CI etal. Survival in chronic hepatitis B. An analysis of 379 patients. Ann Intern Med 1984; 101:613-616.
-
(1984)
Ann Intern Med
, vol.101
, pp. 613-616
-
-
Weissberg, J.I.1
Andres, L.L.2
Smith, C.I.3
-
33
-
-
0027998132
-
Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study. The Investigators of the European Concerted Action on Viral Hepatitis (EUROHEP)
-
Realdi G, Fattovich G, Hadziyannis S etal. Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study. The Investigators of the European Concerted Action on Viral Hepatitis (EUROHEP). J Hepatol 1994; 21:656-666.
-
(1994)
J Hepatol
, vol.21
, pp. 656-666
-
-
Realdi, G.1
Fattovich, G.2
Hadziyannis, S.3
-
34
-
-
0026658646
-
Survival and prognostic indicators in hepatitis B surface antigen-positive cirrhosis of the liver
-
de Jongh FE, Janssen HL, de Man RA, Hop WC, Schalm SW, van Blankenstein M. Survival and prognostic indicators in hepatitis B surface antigen-positive cirrhosis of the liver. Gastroenterology 1992; 103:1630-1635.
-
(1992)
Gastroenterology
, vol.103
, pp. 1630-1635
-
-
de Jongh, F.E.1
Janssen, H.L.2
de Man, R.A.3
Hop, W.C.4
Schalm, S.W.5
van Blankenstein, M.6
-
35
-
-
0032499913
-
A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group
-
Lai CL, Chien RN, Leung NW etal. A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. N Engl J Med 1998; 339:61-68.
-
(1998)
N Engl J Med
, vol.339
, pp. 61-68
-
-
Lai, C.L.1
Chien, R.N.2
Leung, N.W.3
-
36
-
-
0030929584
-
Histological improvement in patients with chronic hepatitis B virus infection treated with lamivudine
-
Honkoop P, de Man RA, Zondervan PE, Schalm SW. Histological improvement in patients with chronic hepatitis B virus infection treated with lamivudine. Liver 1997; 17:103-106.
-
(1997)
Liver
, vol.17
, pp. 103-106
-
-
Honkoop, P.1
de Man, R.A.2
Zondervan, P.E.3
Schalm, S.W.4
-
37
-
-
84883814284
-
Phosphorylated Smad2 and Smad3 signaling: shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C
-
Yamaguchi T, Matsuzaki K, Inokuchi R etal. Phosphorylated Smad2 and Smad3 signaling: shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C. Hepatol Res 2013; 43:1327-1342.
-
(2013)
Hepatol Res
, vol.43
, pp. 1327-1342
-
-
Yamaguchi, T.1
Matsuzaki, K.2
Inokuchi, R.3
-
38
-
-
0033067028
-
Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection
-
Suzuki Y, Kumada H, Ikeda K etal. Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection. J Hepatol 1999; 30:743-748.
-
(1999)
J Hepatol
, vol.30
, pp. 743-748
-
-
Suzuki, Y.1
Kumada, H.2
Ikeda, K.3
-
39
-
-
84873020277
-
Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma
-
Arzumanyan A, Reis HM, Feitelson MA. Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma. Nat Rev Cancer 2013; 13:123-135.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 123-135
-
-
Arzumanyan, A.1
Reis, H.M.2
Feitelson, M.A.3
-
40
-
-
70349240414
-
Chronic hepatitis B: update 2009
-
Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009; 50:661-662.
-
(2009)
Hepatology
, vol.50
, pp. 661-662
-
-
Lok, A.S.1
McMahon, B.J.2
-
42
-
-
0035037858
-
Clinical characteristics and outcome of a cohort of 101 patients with hepatocellular carcinoma
-
Rabe C, Pilz T, Klostermann C etal. Clinical characteristics and outcome of a cohort of 101 patients with hepatocellular carcinoma. World J Gastroenterol 2001; 7:208-215.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 208-215
-
-
Rabe, C.1
Pilz, T.2
Klostermann, C.3
-
43
-
-
81355139582
-
Clinical presentation of hepatocellular carcinoma (HCC) in Asian-Americans versus non-Asian-Americans
-
Wong PY, Xia V, Imagawa DK, Hoefs J, Hu KQ. Clinical presentation of hepatocellular carcinoma (HCC) in Asian-Americans versus non-Asian-Americans. J Immigr Minor Health 2011; 13:842-848.
-
(2011)
J Immigr Minor Health
, vol.13
, pp. 842-848
-
-
Wong, P.Y.1
Xia, V.2
Imagawa, D.K.3
Hoefs, J.4
Hu, K.Q.5
-
44
-
-
79959304448
-
The role of oncogenic viruses in the pathogenesis of hepatocellular carcinoma
-
vii-x.
-
Zemel R, Issachar A, Tur-Kaspa R. The role of oncogenic viruses in the pathogenesis of hepatocellular carcinoma. Clin Liver Dis 2011; 15:261-279, vii-x.
-
(2011)
Clin Liver Dis
, vol.15
, pp. 261-279
-
-
Zemel, R.1
Issachar, A.2
Tur-Kaspa, R.3
-
45
-
-
3543150890
-
Mitotic aberration coupled with centrosome amplification is induced by hepatitis B virus X oncoprotein via the Ras-mitogen-activated protein/extracellular signal-regulated kinase-mitogen-activated protein pathway
-
Yun C, Cho H, Kim SJ etal. Mitotic aberration coupled with centrosome amplification is induced by hepatitis B virus X oncoprotein via the Ras-mitogen-activated protein/extracellular signal-regulated kinase-mitogen-activated protein pathway. Mol Cancer Res 2004; 2:159-169.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 159-169
-
-
Yun, C.1
Cho, H.2
Kim, S.J.3
|