-
1
-
-
0028283503
-
Molecular mechanisms of action of steroid/thyroid receptor superfamily members
-
Tsai MJ, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem. 1994; 86:451-486.
-
(1994)
Annu Rev Biochem
, vol.86
, pp. 451-486
-
-
Tsai, M.J.1
O'Malley, B.W.2
-
2
-
-
82355163442
-
Minireview: Recent advances in extranuclear steroid receptor actions
-
Hammes SR, Levin ER. Minireview: recent advances in extranuclear steroid receptor actions. Endocrinology. 2011;152:4489-4495.
-
(2011)
Endocrinology
, vol.152
, pp. 4489-4495
-
-
Hammes, S.R.1
Levin, E.R.2
-
3
-
-
0035831020
-
Nongenotropic, sexnonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
-
Kousteni S, Bellido T, Plotkin LI, et al. Nongenotropic, sexnonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell. 2001;104:719-730.
-
(2001)
Cell
, vol.104
, pp. 719-730
-
-
Kousteni, S.1
Bellido, T.2
Plotkin, L.I.3
-
4
-
-
0038819062
-
Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
-
Kousteni S, Han L, Chen J-R, et al. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest. 2003;111:1651-1664.
-
(2003)
J Clin Invest
, vol.111
, pp. 1651-1664
-
-
Kousteni, S.1
Han, L.2
Chen, J.-R.3
-
5
-
-
50649101049
-
Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors
-
Madak-Erdogan Z, Kieser KJ, Kim SH, Komm B, Katzenellenbogen JA, Katzenellenbogen BS. Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Mol Endocrinol. 2008;22:2116-2127.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 2116-2127
-
-
Madak-Erdogan, Z.1
Kieser, K.J.2
Kim, S.H.3
Komm, B.4
Katzenellenbogen, J.A.5
Katzenellenbogen, B.S.6
-
6
-
-
4644304613
-
Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: A different perspective on the HRT dilemma
-
Manolagas SC, Kousteni S, Chen JR, Schuller M, Plotkin L, Bellido T. Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma. Kidney Int Suppl. 2004;91:S41-S49.
-
(2004)
Kidney Int Suppl
, vol.91
-
-
Manolagas, S.C.1
Kousteni, S.2
Chen, J.R.3
Schuller, M.4
Plotkin, L.5
Bellido, T.6
-
7
-
-
0037174675
-
Reversal of bone loss in mice by nongenotropic signaling of sex steroids
-
Kousteni S, Chen JR, Bellido T, et al. Reversal of bone loss in mice by nongenotropic signaling of sex steroids. Science. 2002;298:843-846.
-
(2002)
Science
, vol.298
, pp. 843-846
-
-
Kousteni, S.1
Chen, J.R.2
Bellido, T.3
-
8
-
-
0035018612
-
Perspective: Nonreproductive sites of action of reproductive hormones
-
Manolagas SC, Kousteni S. Perspective: nonreproductive sites of action of reproductive hormones. Endocrinology. 2001;142:2200-2204.
-
(2001)
Endocrinology
, vol.142
, pp. 2200-2204
-
-
Manolagas, S.C.1
Kousteni, S.2
-
9
-
-
33748312090
-
Bone protection by estrenes occurs through non-tissue-selective activation of the androgen receptor
-
Windahl SH, Galien R, Chiusaroli R, et al. Bone protection by estrenes occurs through non-tissue-selective activation of the androgen receptor. J Clin Invest. 2006;116:2500-2509.
-
(2006)
J Clin Invest
, vol.116
, pp. 2500-2509
-
-
Windahl, S.H.1
Galien, R.2
Chiusaroli, R.3
-
11
-
-
41549098279
-
Tissue selectivity of the anabolic steroid, 19-nor-4-androstenediol-3β;,17β;-diol in male Sprague Dawley rats: Selective stimulation of muscle mass and bone mineral density relative to prostate mass
-
Page ST, Marck BT, Tolliver JM, Matsumoto AM. Tissue selectivity of the anabolic steroid, 19-nor-4-androstenediol-3β;,17β;-diol in male Sprague Dawley rats: selective stimulation of muscle mass and bone mineral density relative to prostate mass. Endocrinology. 2008;149:1987-1993.
-
(2008)
Endocrinology
, vol.149
, pp. 1987-1993
-
-
Page, S.T.1
Marck, B.T.2
Tolliver, J.M.3
Matsumoto, A.M.4
-
12
-
-
30944440261
-
Identification of estrogen receptor ligands leading to activation of nongenomic signaling pathways while exhibiting only weak transcriptional activity
-
Wessler S, Otto C, Wilck N, Stangl V, Fritzemeier KH. Identification of estrogen receptor ligands leading to activation of nongenomic signaling pathways while exhibiting only weak transcriptional activity. J Steroid Biochem Mol Biol. 2006;98:25-35.
-
(2006)
J Steroid Biochem Mol Biol
, vol.98
, pp. 25-35
-
-
Wessler, S.1
Otto, C.2
Wilck, N.3
Stangl, V.4
Fritzemeier, K.H.5
-
13
-
-
47849107597
-
In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro
-
Otto C, Fuchs I, Altmann H, et al. In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro. J Steroid Biochem Mol Biol. 2008;111:95-100.
-
(2008)
J Steroid Biochem Mol Biol
, vol.111
, pp. 95-100
-
-
Otto, C.1
Fuchs, I.2
Altmann, H.3
-
14
-
-
0034455103
-
Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
-
Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev. 2000;21:115-137.
-
(2000)
Endocr Rev
, vol.21
, pp. 115-137
-
-
Manolagas, S.C.1
-
15
-
-
75149129597
-
From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis
-
Manolagas SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010;31:266-300.
-
(2010)
Endocr Rev
, vol.31
, pp. 266-300
-
-
Manolagas, S.C.1
-
16
-
-
84967614664
-
Sex steroids and the construction and conservation of the adult skeleton
-
Riggs BL, Khosla S, Melton LJ III. Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev. 2002;23:279-302.
-
(2002)
Endocr Rev
, vol.23
, pp. 279-302
-
-
Riggs, B.L.1
Khosla, S.2
Melton L.J, I.I.I.3
-
18
-
-
75149165271
-
The estrogen receptor alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone
-
Martin-Millan M, Almeida M, Ambrogini E, et al. The estrogen receptor alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone. Mol Endocrinol. 2010; 24:323-334.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 323-334
-
-
Martin-Millan, M.1
Almeida, M.2
Ambrogini, E.3
-
19
-
-
34548274444
-
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts
-
Nakamura T, Imai Y, Matsumoto T, et al. Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell. 2007;130:811-823.
-
(2007)
Cell
, vol.130
, pp. 811-823
-
-
Nakamura, T.1
Imai, Y.2
Matsumoto, T.3
-
20
-
-
84873824098
-
Estrogen receptor-alpha signaling in osteoblast progenitors stimulates cortical bone accrual
-
Almeida M, Iyer S, Martin-Millan M, et al. Estrogen receptor-alpha signaling in osteoblast progenitors stimulates cortical bone accrual. J Clin Invest. 2013;123:394-404.
-
(2013)
J Clin Invest
, vol.123
, pp. 394-404
-
-
Almeida, M.1
Iyer, S.2
Martin-Millan, M.3
-
22
-
-
34848878406
-
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
-
Almeida M, Han L, Martin-Millan M, et al. Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem. 2007;282:27285-27297.
-
(2007)
J Biol Chem
, vol.282
, pp. 27285-27297
-
-
Almeida, M.1
Han, L.2
Martin-Millan, M.3
-
23
-
-
77957364479
-
Oxidative stress stimulates apoptosis and activates NF-ΚB in osteoblastic cells via a PKCβ;/p66shc signaling cascade: Counter regulation by estrogens or androgens
-
Almeida M, Han L, Ambrogini E, Bartell SM, Manolagas SC. Oxidative stress stimulates apoptosis and activates NF-ΚB in osteoblastic cells via a PKCβ;/p66shc signaling cascade: counter regulation by estrogens or androgens. Mol Endocrinol. 2010;24:2030-2037.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 2030-2037
-
-
Almeida, M.1
Han, L.2
Ambrogini, E.3
Bartell, S.M.4
Manolagas, S.C.5
-
24
-
-
0142186681
-
A crucial role for thiol antioxidants in estrogen-deficiency bone loss
-
Lean JM, Davies JT, Fuller K, et al. A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J Clin Invest. 2003;112: 915-923.
-
(2003)
J Clin Invest
, vol.112
, pp. 915-923
-
-
Lean, J.M.1
Davies, J.T.2
Fuller, K.3
-
25
-
-
35448995621
-
Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation
-
Grassi F, Tell G, Robbie-Ryan M, et al. Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation. Proc Natl Acad Sci USA. 2007;104: 15087-15092.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15087-15092
-
-
Grassi, F.1
Tell, G.2
Robbie-Ryan, M.3
-
26
-
-
77953392432
-
Estrogens attenuate oxidative stress, osteoblast differentiation and apoptosis by DNA binding-independent actions of the ERα
-
Almeida M, Martin-Millan M, Ambrogini E, et al. Estrogens attenuate oxidative stress, osteoblast differentiation and apoptosis by DNA binding-independent actions of the ERα. J Bone Miner Res. 2010;25:769-781.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 769-781
-
-
Almeida, M.1
Martin-Millan, M.2
Ambrogini, E.3
-
27
-
-
33344476520
-
Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action
-
Harrington WR, Kim SH, Funk CC, et al. Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Mol Endocrinol. 2006;20: 491-502.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 491-502
-
-
Harrington, W.R.1
Kim, S.H.2
Funk, C.C.3
-
28
-
-
33751005875
-
Hormone-PAMAM dendrimer conjugates: Polymer dynamics and tether structure affect ligand access to receptors
-
Kim SH, Katzenellenbogen JA. Hormone-PAMAM dendrimer conjugates: polymer dynamics and tether structure affect ligand access to receptors. Angew Chem Int Ed Engl. 2006;45:7243-7248.
-
(2006)
Angew Chem Int Ed Engl
, vol.45
, pp. 7243-7248
-
-
Kim, S.H.1
Katzenellenbogen, J.A.2
-
29
-
-
20444445144
-
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer
-
Kukowska-Latallo JF, Candido KA, Cao Z, et al. Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res. 2005;65:5317- 5324.
-
(2005)
Cancer Res
, vol.65
, pp. 5317
-
-
Kukowska-Latallo, J.F.1
Candido, K.A.2
Cao, Z.3
-
30
-
-
33644864871
-
Targeted delivery of methotrexate to epidermal growth factor receptor-positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates
-
Wu G, Barth RF, Yang W, Kawabata S, Zhang L, Green-Church K. Targeted delivery of methotrexate to epidermal growth factor receptor-positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates. Mol Cancer Ther. 2006;5:52-59.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 52-59
-
-
Wu, G.1
Barth, R.F.2
Yang, W.3
Kawabata, S.4
Zhang, L.5
Green-Church, K.6
-
31
-
-
77955006975
-
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
-
Chambliss KL, Wu Q, Oltmann S, et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest. 2010;120: 2319-2330.
-
(2010)
J Clin Invest
, vol.120
, pp. 2319-2330
-
-
Chambliss, K.L.1
Wu, Q.2
Oltmann, S.3
-
32
-
-
26844486477
-
IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice
-
O'Brien CA, Jilka RL, Fu Q, Stewart S, Weinstein RS, Manolagas SC. IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice. Am J Physiol Endocrinol Metab. 2005;289:E784-E793.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
O'Brien, C.A.1
Jilka, R.L.2
Fu, Q.3
Stewart, S.4
Weinstein, R.S.5
Manolagas, S.C.6
-
33
-
-
78349266526
-
Decreased oxidative stress and greater bone anabolism in the aged, as compared to the young, murine skeleton by parathyroid hormone
-
Jilka RL, Almeida M, Ambrogini E, Han L, Roberson PK, Weinstein RS, Manolagas SC. Decreased oxidative stress and greater bone anabolism in the aged, as compared to the young, murine skeleton by parathyroid hormone. Aging Cell. 2010;9:851-867.
-
(2010)
Aging Cell
, vol.9
, pp. 851-867
-
-
Jilka, R.L.1
Almeida, M.2
Ambrogini, E.3
Han, L.4
Roberson, P.K.5
Weinstein, R.S.6
Manolagas, S.C.7
-
34
-
-
77954756294
-
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
-
Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Muller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 2010; 25:1468-1486.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1468-1486
-
-
Bouxsein, M.L.1
Boyd, S.K.2
Christiansen, B.A.3
Guldberg, R.E.4
Jepsen, K.J.5
Muller, R.6
-
35
-
-
0035057030
-
Attenuation of the self-renewal of transit amplifying osteoblast progenitors in the murine bone marrow by 17β;estradiol
-
DiGregorio G, Yamamoto M, Ali A, Abe E, Roberson P, Manolagas SC, Jilka RL. Attenuation of the self-renewal of transit amplifying osteoblast progenitors in the murine bone marrow by 17β;estradiol. J Clin Invest. 2001;107:803-812.
-
(2001)
J Clin Invest
, vol.107
, pp. 803-812
-
-
Digregorio, G.1
Yamamoto, M.2
Ali, A.3
Abe, E.4
Roberson, P.5
Manolagas, S.C.6
Jilka, R.L.7
-
36
-
-
10244220999
-
Species differences in growth requirements for bone marrow stromal fibroblast colony formation in vitro
-
Kuznetsov S, Robey PG. Species differences in growth requirements for bone marrow stromal fibroblast colony formation in vitro. Calcif Tissue Int. 1996;59:265-270.
-
(1996)
Calcif Tissue Int
, vol.59
, pp. 265-270
-
-
Kuznetsov, S.1
Robey, P.G.2
-
37
-
-
29244446792
-
Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by β;-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
-
Almeida M, Han L, Bellido T, Manolagas SC, Kousteni S. Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by β;-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J Biol Chem. 2005;280:41342-41351.
-
(2005)
J Biol Chem
, vol.280
, pp. 41342-41351
-
-
Almeida, M.1
Han, L.2
Bellido, T.3
Manolagas, S.C.4
Kousteni, S.5
-
39
-
-
0032722149
-
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin
-
Plotkin LI, Weinstein RS, Parfitt AM, Roberson PK, Manolagas SC, Bellido T. Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. J Clin Invest. 1999;104:1363-1374.
-
(1999)
J Clin Invest
, vol.104
, pp. 1363-1374
-
-
Plotkin, L.I.1
Weinstein, R.S.2
Parfitt, A.M.3
Roberson, P.K.4
Manolagas, S.C.5
Bellido, T.6
-
40
-
-
33846900615
-
Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor
-
Kousteni S, Almeida M, Han L, Bellido T, Jilka RL, Manolagas SC. Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor. Mol Cell Biol. 2007;27:1516-1530.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1516-1530
-
-
Kousteni, S.1
Almeida, M.2
Han, L.3
Bellido, T.4
Jilka, R.L.5
Manolagas, S.C.6
-
41
-
-
78049380720
-
Skeletal sexual dimorphism: Relative contribution of sex steroids, GH--IGF1, and mechanical loading
-
Callewaert F, Sinnesael M, Gielen E, Boonen S, Vanderschueren D. Skeletal sexual dimorphism: relative contribution of sex steroids, GH--IGF1, and mechanical loading. J Endocrinol. 2010;207:127-134.
-
(2010)
J Endocrinol
, vol.207
, pp. 127-134
-
-
Callewaert, F.1
Sinnesael, M.2
Gielen, E.3
Boonen, S.4
Vanderschueren, D.5
-
42
-
-
0026012094
-
High concentrations of 17β;-estradiol stimulate trabecular bone formation in adult female rats
-
Tobias JH, Chow J, Colston KW, Chambers TJ. High concentrations of 17β;-estradiol stimulate trabecular bone formation in adult female rats. Endocrinology. 1991;128:408-412.
-
(1991)
Endocrinology
, vol.128
, pp. 408-412
-
-
Tobias, J.H.1
Chow, J.2
Colston, K.W.3
Chambers, T.J.4
-
43
-
-
0034081468
-
Is high-dose estrogen-induced osteogenesis in the mouse mediated by an estrogen receptor?
-
Samuels A, Perry MJ, Goodship AE, Fraser WD, Tobias JH. Is high-dose estrogen-induced osteogenesis in the mouse mediated by an estrogen receptor? Bone. 2000;27:41-46.
-
(2000)
Bone
, vol.27
, pp. 41-46
-
-
Samuels, A.1
Perry, M.J.2
Goodship, A.E.3
Fraser, W.D.4
Tobias, J.H.5
-
44
-
-
84865446399
-
Receptor activator of nuclear factor ΚB Ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss
-
Onal M, Xiong J, Chen X, et al. Receptor activator of nuclear factor ΚB Ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. J Biol Chem. 2012;287: 29851-29860.
-
(2012)
J Biol Chem
, vol.287
, pp. 29851-29860
-
-
Onal, M.1
Xiong, J.2
Chen, X.3
-
45
-
-
77952111123
-
Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: A cross-sectional study
-
Zebaze RM, Ghasem-Zadeh A, Bohte A, et al. Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. 2010;375:1729-1736.
-
(2010)
Lancet
, vol.375
, pp. 1729-1736
-
-
Zebaze, R.M.1
Ghasem-Zadeh, A.2
Bohte, A.3
|