Homoisoflavanone prevents mast cell activation and allergic responses by inhibition of Syk signaling pathway

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 69, Issue 4, 2014, Pages 453-462

  Lee, Y S ^a   Hur, S ^a   Kim, T Y ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

5 lipoxygenase; anti allergic responses; cyclooxygenase 2; homoisoflavanone; Syk

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 2,4 DINITROPHENOL; 5,7 DIHYDROXY 3 (3 HYDROXY 4 METHOXY BENZYL)CHROMAN 4 ONE; CALCIMYCIN; COMPOUND 48-80; CYTOSOLIC PHOSPHOLIPASE A2; DEXAMETHASONE; FLAVANONE DERIVATIVE; IMMUNOGLOBULIN E; INTERLEUKIN 6; LEUKOTRIENE B4; LEUKOTRIENE C4; PROTEIN KINASE SYK; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIALLERGIC ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRANULATION ASSAY; DOWN REGULATION; DRUG ACTIVITY; EAR EDEMA; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REPRESSION; HUMAN; HUMAN CELL; MAST CELL; MOUSE; MOUSE MODEL; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

5-LIPOXYGENASE; ANTI-ALLERGIC RESPONSES; CYCLOOXYGENASE-2; HOMOISOFLAVANONE; SYK;

ANIMALS; ANTI-ALLERGIC AGENTS; ARACHIDONATE 5-LIPOXYGENASE; BONE MARROW CELLS; CELL DEGRANULATION; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; HUMANS; HYPERSENSITIVITY; INFLAMMATION MEDIATORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOFLAVONES; LEUKOTRIENES; MAST CELLS; MICE; PROSTAGLANDINS; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE; SIGNAL TRANSDUCTION;

EID: 84895539091     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12356     Document Type: Article

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