Piceatannol, a Syk-selective tyrosine kinase inhibitor, attenuated antigen challenge of guinea pig airways in vitro

European Journal of Pharmacology

Volumn 443, Issue 1-3, 2002, Pages 189-196

  Seow, Cherng Jye ^a   Chue, Sung Chian ^a   Wong, W S Fred ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Arachidonic acid; Bronchus; Histamine; Leukotriene D4; Ovalbumin; Schultz Dale reaction

Indexed keywords

ANTIGEN; HISTAMINE; OVALBUMIN; PEPTIDOLEUKOTRIENE; PICEATANNOL; PROTEIN TYROSINE KINASE INHIBITOR;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRONCHUS; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG SELECTIVITY; GUINEA PIG; HISTAMINE RELEASE; IN VITRO STUDY; MALE; MAST CELL DEGRANULATION; NONHUMAN; PRIORITY JOURNAL; TISSUE PREPARATION;

AIRWAY OBSTRUCTION; ANAPHYLAXIS; ANIMALS; BRONCHOCONSTRICTION; ENZYME INHIBITORS; ENZYME PRECURSORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUINEA PIGS; HISTAMINE RELEASE; INJECTIONS, INTRAPERITONEAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOTRIENES; LUNG; MALE; OVALBUMIN; PROTEIN-TYROSINE KINASES; STILBENES;

EID: 0037123868     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01534-0     Document Type: Article

References (34)

1. 4 on canine bronchial smooth muscle
2. Functional comparison of FcεRI, FcγRII, and FcγRIII in mast cells
3. Inflammatory mediators of asthma: An update
4. Asthma
5. The Schultz-Dale reaction: A review
6. Signaling takes shape in the immune system
7. Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma
8. Signaling networks: The origins of cellular multitasking
9. Tyrosine phosphorylation is required for mast cell activation by FcεRI cross-linking
10. Identification of the FcεRI-activated tyrosine Lyn, Syk, and Zap-70 in human basophils
11. Multiple defects in FcεRI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion
12. The high-affinity IgE receptor (FcεRI): From physiology to pathology
13. Characteristics of formation and further metabolism of leukotrienes in the chopped human lung
14. Proximal protein tyrosine kinases in immunoreceptor signaling
15. The effect of tyrosine kinase inhibitors on IgE-mediated histamine release from human lung mast cells and basophils
16. 3 signaling in platelets
17. Protein kinase inhibitors: The tyrosine-specific protein kinases
18. A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeate
19. Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells
20. 2 is phosphorylated and activated by MAP kinase
21. ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of FcεRI-mediated activation of Syk
22. 2 release via mechanistically distinct processes
23. Inhibition of mast cell FcεRI-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol
24. Immunologically mediated signaling in basophils and mast cells: Finding therapeutic targets for allergic diseases in the human FcεRI signaling pathway
25. Syk activation initiates downstream signaling events during human polymorphonuclear leukocyte phagocytosis
26. Molecular consequences of human mast cell activation following immunoglobulin E-high-affinity immunoglobulin E receptor (IgE-FcεRI) interaction
27. Influence of indomethacin and L-cysteine on histamine and peptidoleukotriene release from superfused tracheas taken from guinea pigs passively sensitized with IgG1 and IgE antibodies
28. Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics
29. Signal transduction by immunoglobulin Fc receptors
30. Inhibitors of tyrosine kinase signaling cascade attenuated antigen challenge of guinea-pig airways in vitro
31. Effects of mitogen-activated protein kinase kinase inhibitor PD098059 on antigen challenge of guinea-pig airways in vitro
32. Effects of tyrosine kinase inhibitors on antigen challenge of guinea pig lung in vitro
33. Transfection of Syk protein tyrosine reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells
34. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-α and release of arachidonic acid in mast cells