Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation

Journal of Allergy and Clinical Immunology

Volumn 123, Issue 1, 2009, Pages 249-257

  Ohnishi, Hiroshi ^a   Takeda, Katsuyuki ^a   Domenico, Joanne ^a   Lucas, Joseph J ^a   Miyahara, Nobuaki ^a   Swasey, Christina H ^a   Dakhama, Azzeddine ^a   Gelfand, Erwin W ^a  

^a DEPARTMENT OF MEDICINE   (United States)

Author keywords

Allergy; asthma; effector memory T cell; mitogen activated protein kinase; signal transduction

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CD3 ANTIBODY; INTERLEUKIN 13; INTERLEUKIN 5; LEUKOTRIENE B4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD28;

ADOPTIVE TRANSFER; AIRWAY HYPERRESPONSIVENESS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM MOBILIZATION; CD8+ T LYMPHOCYTE; CELL TYPE; CELLULAR IMMUNITY; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DRUG EFFECT; EFFECTOR CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EOSINOPHIL; GOBLET CELL; HUMORAL IMMUNITY; HYPERSENSITIVITY; INFLAMMATION; LUNG LAVAGE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; METAPLASIA; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RESPIRATORY TRACT DISEASE;

ADOPTIVE TRANSFER; ALLERGENS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; BUTADIENES; CALCIUM; CD8-POSITIVE T-LYMPHOCYTES; CHEMOTAXIS; ENZYME INHIBITORS; EOSINOPHILS; GOBLET CELLS; IMMUNOLOGIC MEMORY; INFLAMMATION; LEUKOTRIENE B4; LUNG; MAP KINASE SIGNALING SYSTEM; METAPLASIA; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; RECEPTORS, LEUKOTRIENE B4; RESPIRATORY HYPERSENSITIVITY; TH2 CELLS;

EID: 58149122862     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2008.10.054     Document Type: Article

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