Visceral adipose tissue and leptin increase colonic epithelial tight junction permeability via a RhoA-ROCK-dependent pathway

FASEB Journal

Volumn 28, Issue 3, 2014, Pages 1059-1070

  Le Dréan, Gwenola ^a   Haure Mirande, Vianney ^a   Ferrier, Laurent ^b   Bonnet, Christian ^a   Hulin, Philippe ^a   De Coppet, Pierre ^a   Segain, Jean Pierre ^a  

^a UNIVERSITÉ DE NANTES   (France)

^b CEMAGREF   (France)

Author keywords

Adipocytesactin cytoskeleton; Adipokines; Barrier

Indexed keywords

ADIPONECTIN; F ACTIN; LEPTIN; PROTEIN ZO1; RHO KINASE; ADIPOCYTOKINE; PRIMER DNA; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELLULAR PARAMETERS; COLON MUCOSA; CONTROLLED STUDY; CYTOSKELETON; EX VIVO STUDY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE EPITHELIUM CELL; INTRAABDOMINAL FAT; INTRAUTERINE GROWTH RETARDATION; LEAN BODY WEIGHT; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TIGHT JUNCTION; TRANSEPITHELIAL RESISTANCE; ACTIN FILAMENT; ANIMAL; BARRIER; COLON; FEMALE; INTESTINE MUCOSA; NUCLEOTIDE SEQUENCE; PERMEABILITY; PHYSIOLOGY; PREGNANCY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ACTIN CYTOSKELETON; ADIPOCYTES; ADIPOKINES; BARRIER;

ANIMALS; BASE SEQUENCE; COLON; DNA PRIMERS; FEMALE; INTESTINAL MUCOSA; INTRA-ABDOMINAL FAT; LEPTIN; MALE; PERMEABILITY; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; TIGHT JUNCTIONS;

EID: 84895532224     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-234203     Document Type: Article

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