|
|
Volumn 76, Issue , 2014, Pages 376-386
|
|
Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents
a,b
a
a
|
|
Author keywords
AChE inhibitors; Anti Alzheimer; A aggregation inhibitors; Galantamine analogs; Neuroprotective agents
|
|
Indexed keywords
2 METHOXY 5 METHYL 9 (PHENYLSULFONYL) 9H CARBAZOLE;
2 METHOXY 5 METHYL 9H CARBAZOLE;
3 CHLORO N ISOPROPYL N [(7 METHOXY 9H CARBAZOL 4 YL) METHYL]PROPANAMIDE;
3 CHLORO N ISOPROPYL N [(7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL]PROPANAMIDE;
3 METHOXY 7 METHYLDIBENZO [B,D]FURAN;
4 METHOXY 2 (3 METHYLPHENOXY) 1 NITROBENZENE;
4 METHOXY 2 (3 METHYLPHENOXY)PHENYLAMINE;
4 METHOXY 2' METHYL 2 NITRO 1,1' BIPHENYL;
5 (BROMOMETHYL) 2 METHOXY 9 (PHENYLSULFONYL) 9H CARBAZOLE;
5 [(ISOPROPYLAMINO) METHYL] 9H CARBAZOL 2 OL;
7 METHOXY 1 METHYLDIBENZO[B,D]FURAN;
9 [(ISOPROPYLAMINO) METHYL]DIBENZO[B,D]FURAN 3 OL;
ACETYLCHOLINE;
AMYLOID BETA PROTEIN[1-42];
GALANTAMINE;
GLUTATHIONE;
N ((7 METHOXY 9 (PHENYLSULFONYL) 9H CARBAZOL 4 YL)METHYL)PROPAN 2 AMINE;
N ((7 METHOXY 9H CARBAZOL 4 YL)METHYL)PROPAN 2 AMINE;
N ((7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL) N METHYLETHANAMINE;
N ((7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL)ETHANAMINE;
N ((7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL)PROPAN 2 AMINE;
N BENZYL 1 (7 METHOXY 9 (PHENYLSULFONYL) 9H CARBAZOL 4 YL)METHANAMINE;
N BENZYL 1 (7 METHOXY 9H CARBAZOL 4 YL)METHANAMINE;
N ETHYL N ((7 METHOXY 9 (PHENYLSULFONYL) 9H CARBAZOL 4 YL)METHYL)ETHANAMINE;
N ETHYL N ((7 METHOXY 9H CARBAZOL 4 YL)METHYL)ETHANAMINE;
N ETHYL N ((7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL)ETHANAMINE;
N ISOPROPYL N [(7 METHOXY 9H CARBAZOL 4 YL)METHYL] 3 NITROPROPANAMIDE;
N ISOPROPYL N [(7 METHOXYDIBENZO[B,D]FURAN 1 YL)METHYL] 3 NITROPROPANAMIDE;
NITRATE;
TACRINE;
UNCLASSIFIED DRUG;
CHOLINESTERASE INHIBITOR;
NITRIC OXIDE;
ALZHEIMER DISEASE;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
BIOLOGICAL ACTIVITY;
CELL VIABILITY;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG DESIGN;
DRUG POTENCY;
DRUG SAFETY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
ENZYME INHIBITION;
EX VIVO STUDY;
FEMALE;
IC 50;
IN VITRO STUDY;
IN VIVO STUDY;
LIVER TOXICITY;
MAXIMUM TOLERATED DOSE;
NERVE CELL;
NEUROPROTECTION;
NONHUMAN;
PROTEIN AGGREGATION;
RAT;
SPATIAL MEMORY;
ANIMAL;
ATOMIC FORCE MICROSCOPY;
CHEMISTRY;
ELECTROSPRAY MASS SPECTROMETRY;
METABOLISM;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
SYNTHESIS;
WISTAR RAT;
ALZHEIMER DISEASE;
ANIMALS;
CHOLINESTERASE INHIBITORS;
DRUG DESIGN;
FEMALE;
GALANTAMINE;
MAGNETIC RESONANCE SPECTROSCOPY;
MICROSCOPY, ATOMIC FORCE;
NITRIC OXIDE;
RATS;
RATS, WISTAR;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
|
|
EID: 84895527205
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2014.02.035 Document Type: Article |
|
Times cited : (63)
|
|
References (30)
|
