ABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer

OncoTargets and Therapy

Volumn 7, Issue , 2014, Pages 343-351

  Zhao, Xiaoting ^a   Guo, Yinan ^a   Yue, Wentao ^a   Zhang, Lina ^a   Gu, Meng ^a   Wang, Yue ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

ABCC4; Cell cycle; Cell proliferation; Lung cancer

Indexed keywords

LENTIVIRUS VECTOR; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; RETINOBLASTOMA PROTEIN;

ADOLESCENT; ADULT; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER PATIENT; CANCER THERAPY; CANCER TISSUE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; COLONY FORMATION; DOWN REGULATION; DRUG TARGETING; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MALE; MTS ASSAY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

EID: 84895432993     PISSN: 11786930     EISSN: None     Source Type: Journal    
DOI: 10.2147/OTT.S56029     Document Type: Article

References (33)

1. Ramalingam SS, Owonikoko TK, Khuri FR. Lung cancer: new biological insights and recent therapeutic advances. CA Cancer J Clin. 2011;61(2):91-112.
2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90.
3. Pao W, Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol. 2011;12(2):175-180.
4. Sodani K, Patel A, Kathawala RJ, Chen ZS. Multidrug resistance associated proteins in multidrug resistance. Chin J Cancer. 2012;31(2): 58-72.
5. Pattabiraman PP, Pecen PE, Rao PV. MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure. Invest Ophthalmol Vis Sci. 2013;54(3):1636-1649.
6. Robillard KR, Hoque T, Bendayan R. Expression of ATP-binding cassette membrane transporters in rodent and human Sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier. J Pharmacol Exp Ther. 2012;340(1):96-108.
7. Slot AJ, Molinski SV, Cole SP. Mammalian multidrug-resistance proteins (MRPs). Essays Biochem. 2011;50(1):179-207.
8. Zhang Y, Schuetz JD, Elmquist WF, Miller DW. Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells. J Pharmacol Exp Ther. 2004;311(2): 449-455.
9. Westlake CJ, Cole SP, Deeley RG. Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking. Mol Biol Cell. 2005;16(5):2483-2492.
10. Zhou SF, Wang LL, Di YM, etal. Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. Curr Med Chem. 2008;15(20):1981-2039.
11. Borst P, de Wolf C, van de Wetering K. Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch. 2007;453(5):661-673.
12. Gelhaus SL, Gilad O, Hwang WT, Penning TM, Blair IA. Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells. Toxicol Lett. 2012;209(1):58-66.
13. Kool M, de Haas M, Scheffer GL, etal. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res. 1997;57(16):3537-3547.
14. Montani M, Herrmanns T, Muntener M, Wild P, Sulser T, Kristiansen G. Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression. Virchows Arch. 2013;462(4):437-443.
15. Norris MD, Smith J, Tanabe K, etal. Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro. Mol Cancer Ther. 2005;4(4): 547-553.
16. Dick FA, Rubin SM. Molecular mechanisms underlying RB protein function. Nat Rev Mol Cell Biol. 2013;14(5):297-306.
17. Ansari M, Sauty G, Labuda M, etal. Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia. Blood. 2009;114(7): 1383-1386.
18. Copsel S, Garcia C, Diez F, etal. Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. J Biol Chem. 2011;286(9):6979-6988.
19. Ho LL, Kench JG, Handelsman DJ, etal. Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. Prostate. 2008;68(13):1421-1429.
20. Cai C, Omwancha J, Hsieh CL, Shemshedini L. Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. Prostate Cancer Prostatic Dis. 2007;10(1):39-45.
21. Oprea-Lager DE, Bijnsdorp IV, Van Moorselaar RJ, Van Den Eertwegh AJ, Hoekstra OS, Geldof AA. ABCC4 decreases docetaxel and not cabazitaxel efficacy in prostate cancer cells in vitro. Anticancer Res. 2013;33(2):387-391.
22. Warrier S, Pavanram P, Raina D, Arvind M. Study of chemoresistant CD133+ cancer stem cells from human glioblastoma cell line U138MG using multiple assays. Cell Biol Int. 2012;36(12):1137-1143.
23. Hendig D, Langmann T, Zarbock R, Schmitz G, Kleesiek K, Gotting C. Characterization of the ATP-binding cassette transporter gene expression profile in Y79: a retinoblastoma cell line. Mol Cell Biochem. 2009;328(1-2):85-92.
24. Heimerl S, Bosserhoff AK, Langmann T, Ecker J, Schmitz G. Mapping ATP-binding cassette transporter gene expression profiles in melanocytes and melanoma cells. Melanoma Res. 2007;17(5):265-273.
25. Hagmann W, Jesnowski R, Faissner R, Guo C, Lohr JM. ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells. Pancreatology. 2009; 9(1-2):136-144.
26. Sethi S, Benninger MS, Lu M, Havard S, Worsham MJ. Noninvasive molecular detection of head and neck squamous cell carcinoma: an exploratory analysis. Diagn Mol Pathol. 2009;18(2):81-87.
27. Peng XX, Shi Z, Damaraju VL, etal. Up-regulation of MRP4 and down-regulation of influx transporters in human leukemic cells with acquired resistance to 6-mercaptopurine. Leuk Res. 2008;32(5):799-809.
28. Chai R, Yu ZQ, Fu CG, etal. [Preliminary study on relationship between multi-drug resistance-associated protein 4 and radiosensitivity of rectal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi. 2011;14(8):627-630. Chinese.
29. Moyer AM, Sun Z, Batzler AJ, etal. Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. Cancer Epidemiol Biomarkers Prev. 2010;19(3):811-821.
30. Henderson MJ, Haber M, Porro A, etal. ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux. J Natl Cancer Inst. 2011;103(16):1236-1251.
31. Rodriguez MR, Diez F, Ventimiglia MS, etal. Atrial natriuretic factor stimulates efflux of cAMP in rat exocrine pancreas via multidrug resistance-associated proteins. Gastroenterology. 2011;140(4): 1292-1302.
32. Giacinti C, Giordano A. RB and cell cycle progression. Oncogene. 2006;25(38):5220-5227.
33. Korenjak M, Brehm A. E2F-Rb complexes regulating transcription of genes important for differentiation and development. Curr Opin Genet Dev. 2005;15(5):520-527.