Characterization of the ATP-binding cassette transporter gene expression profile in Y79: A retinoblastoma cell line

Molecular and Cellular Biochemistry

Volumn 328, Issue 1-2, 2009, Pages 85-92

  Hendig, Doris ^a   Langmann, Thomas ^b   Zarbock, Ralf ^a   Schmitz, Gerd ^b   Kleesiek, Knut ^a   Götting, Christian ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

ABC protein; ABC transporter; Gene expression; Retinoblastoma; Y79

Indexed keywords

ABC TRANSPORTER; ATP BINDING CASSETTE TRANSPORTER A12; ATP BINDING CASSETTE TRANSPORTER A7; ATP BINDING CASSETTE TRANSPORTER B10; ATP BINDING CASSETTE TRANSPORTER B7; ATP BINDING CASSETTE TRANSPORTER C1; ATP BINDING CASSETTE TRANSPORTER C4; ATP BINDING CASSETTE TRANSPORTER D3; ATP BINDING CASSETTE TRANSPORTER E1; ATP BINDING CASSETTE TRANSPORTER F1; ATP BINDING CASSETTE TRANSPORTER F2; ATP BINDING CASSETTE TRANSPORTER F3; CALCEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 6; MULTIDRUG RESISTANCE PROTEIN 7; RNA; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; GENE ACTIVITY; GENE EXPRESSION PROFILING; GENE LOCATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; PROTEIN TRANSPORT; RETINOBLASTOMA; TISSUE DISTRIBUTION;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; FLUORESCEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; RETINOBLASTOMA;

EID: 67650311598     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0077-6     Document Type: Article

References (45)

1. Dean M, Hamon Y, Chimini G (2001) The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 42:1007-1017
2. Haimeur A, Conseil G, Deeley RG, Cole SP (2004) The MRP-related and BCRP/ ABCG2 multidrug resistance proteins: Biology, substrate specificity and regulation. Curr Drug Metab 5:21-53. doi: 10.2174/1389200043489199
3. Deeley RG, Westlake C, Cole SP (2006) Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 86:849-899. doi: 10.1152/physrev.00035.2005
4. Mayer F, Stoop H, Scheffer GL, Scheper R, Oosterhuis JW, Looijenga LH, Bokemeyer C (2003) Molecular determinants of treatment response in human germ cell tumors. Clin Cancer Res 9:767-773
5. Szakacs G, Annereau JP, Lababidi S, Shankavaram U, Arciello A, Bussey KJ, Reinhold W, Guo Y, Kruh GD, Reimers M, Weinstein JN, Gottesman MM (2004) Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells. Cancer Cell 6:129-137. doi: 10.1016/ j.ccr.2004.06.026
6. Gillet JP, Efferth T, Steinbach D, Hamels J, de Longueville F, Bertholet V, Remacle J (2004) Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes. Cancer Res 64:8987-8993. doi: 10.1158/ 0008-5472.CAN-04-1978
7. Dyer MA, Rodriguez-Galindo C, Wilson MW (2005) Use of preclinical models to improve treatment of retinoblastoma. PLoS Med 2:e332. doi: 10.1371/ journal.pmed.0020332
8. Melamud A, Palekar R, Singh A (2006) Retinoblastoma. Am Fam Physician 73:1039-1044
9. Chan HS, Lu Y, Grogan TM, Haddad G, Hipfner DR, Cole SP, Deeley RG, Ling V, Gallie BL (1997) Multidrug resistance protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein. Cancer Res 57:2325-2330
10. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84:265-269. doi: 10.1073/pnas.84.1.265
11. Reid TW, Albert DM, Rabson AS, Russell P, Craft J, Chu EW, Tralka TS, Wilcox JL (1974) Characteristics of an established cell line of retinoblastoma. J Natl Cancer Inst 53:347-360
12. McFall RC, Sery TW, Makadon M (1977) Characterization of a new continuous cell line derived from a human retinoblastoma. Cancer Res 37:1003-1010
13. Langmann T, Mauerer R, Schmitz G (2006) Human ATP-binding cassette transporter TaqMan low-density array: Analysis of macrophage differentiation and foam cell formation. Clin Chem 52:310-313. doi: 10.1373/clinchem.2005.059774
14. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408
15. Essodaigui M, Broxterman HJ, Garnier-Suillerot A (1998) Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein. Biochemistry 37:2243-2250. doi: 10.1021/bi9718043
16. Versantvoort CH, Bagrij T, Wright KA, Twentyman PR (1995) On the relationship between the probenecid-sensitive transport of daunorubicin or calcein and the glutathione status of cells overexpressing the multidrug resistance-associated protein (MRP). Int J Cancer 63:855-862. doi: 10.1002/ijc.2910630617
17. McAleer MA, Breen MA, White NL, Matthews N (1999) pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells. J Biol Chem 274:23541-23548. doi: 10.1074/jbc.274.33.23541
18. Prime-Chapman HM, Fearn RA, Cooper AE, Moore V, Hirst BH (2004) Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. J Pharmacol Exp Ther 311:476-484. doi: 10.1124/jpet.104.068775
19. Langmann T, Mauerer R, Zahn A, Moehle C, Probst M, Stremmel W, Schmitz G (2003) Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues. Clin Chem 49:230-238. doi: 10.1373/49.2.230
20. Hendig D, Langmann T, Kocken S, Zarbock R, Szliska C, Schmitz G, Kleesiek K, Götting C (2008) Gene expression profiling of ABC transporters in dermal fibroblasts of pseudoxanthoma elasticum patients identifies new candidates involved in PXE pathogenesis. Lab Invest 88:1303-1315. doi: 10.1038/labinvest.2008.96
21. Schmitz G, Liebisch G, Langmann T (2006) Lipidomic strategies to study structural and functional defects of ABC-transporters in cellular lipid trafficking. FEBS Lett 580:5597-5610. doi: 10.1016/j.febslet.2006.08.014
22. Akiyama M (2006) Pathomechanisms of harlequin ichthyosis and ABCA transporters in human diseases. Arch Dermatol 142:914-918. doi: 10.1001/ archderm.142.7.914
23. Graf SA, Haigh SE, Corson ED, Shirihai OS (2004) Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me). J Biol Chem 279:42954-42963. doi: 10.1074/ jbc.M405040200
24. Allikmets R, Raskind WH, Hutchinson A, Schueck ND, Dean M, Koeller DM (1999) Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A). Hum Mol Genet 8:743-749. doi: 10.1093/hmg/8.5.743
25. Kool M, de Haas M, Scheffer GL, Scheper RJ, van Eijk MJ, Juijn JA, Baas F, Borst P (1997) Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57:3537-3547
26. Lautier D, Canitrot Y, Deeley RG, Cole SP (1996) Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem Pharmacol 52:967-977. doi: 10.1016/0006-2952(96)00450-9
27. Yasui K, Mihara S, Zhao C, Okamoto H, Saito-Ohara F, Tomida A, Funato T, Yokomizo A, Naito S, Imoto I, Tsuruo T, Inazawa J (2004) Alteration in copy numbers of genes as a mechanism for acquired drug resistance. Cancer Res 64:1403-1410. doi: 10.1158/0008-5472.CAN-3263-2
28. Borst P, de Wolf C, van de Wetering K (2007) Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch 453:661-673. doi: 10.1007/s00424-006-0054-9
29. Dunster K, Lai FP, Sentry JW (2005) Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Clin Exp Immunol 140:556-563. doi: 10.1111/j.1365-2249.2005.02774.x
30. Heimerl S, Bosserhoff AK, Langmann T, Ecker J, Schmitz G (2007) Mapping ATP-binding cassette transporter gene expression profiles in melanocytes and melanoma cells. Melanoma Res 17:265-273
31. Chen ZQ, Dong J, Ishimura A, Daar I, Hinnebusch AG, Dean M (2006) The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors. J Biol Chem 281:7452-7457. doi: 10.1074/jbc.M510603200
32. Tyzack JK, Wang X, Belsham GJ, Proud CG (2000) ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner. J Biol Chem 275:34131-34139. doi: 10.1074/ jbc.M002868200
33. Tsuda H, Ito YM, Ohashi Y, Wong KK, Hashiguchi Y, Welch WR, Berkowitz RS, Birrer MJ, Mok SC (2005) Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses. Clin Cancer Res 11:6880-6888. doi: 10.1158/ 1078-0432.CCR-05-0751
34. Wenzel JJ, Piehler A, Kaminski WE (2007) ABC A-subclass proteins: gatekeepers of cellular phospho- and sphingolipid transport. Front Biosci 12:3177-3193. doi: 10.2741/2305
35. Kamarashev J, Ferrone S, Seifert B, Boni R, Nestle FO, Burg G, Dummer R (2001) TAP1 down-regulation in primary melanoma lesions: An independent marker of poor prognosis. Int J Cancer 95:23-28. doi: 10.1002/ 1097-0215(20010120)95:1<23::AID-IJC1004>3.0.CO;2-4
36. Pasquali-Ronchetti I, Garcia-Fernandez MI, Boraldi F, Quaglino D, Gheduzzi D, De Vincenzi Paolinelli C, Tiozzo R, Bergamini S, Ceccarelli D, Muscatello U (2006) Oxidative stress in fibroblasts from patients with pseudoxanthoma elasticum: Possible role in the pathogenesis of clinical manifestations. J Pathol 208:54-61. doi: 10.1002/path.1867
37. Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, Klaassen CD (2007) Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology 46:1597-1610. doi: 10.1002/hep.21831
38. Bryan J, Munoz A, Zhang X, Dufer M, Drews G, Krippeit-Drews P, Aguilar-Bryan L (2007) ABCC8 and ABCC9: ABC transporters that regulate K+ channels. Pflugers Arch 453:703-718. doi: 10.1007/s00424-006-0116-z
39. Filho JP, Correa ZM, Odashiro AN, Coutinho AB, Martins MC, Erwenne CM, Burnier MN Jr (2005) Histopathological features and P-glycoprotein expression in retinoblastoma. Invest Ophthalmol Vis Sci 46:3478-3483. doi: 10.1167/iovs.04-1290
40. Kamburoglu G, Kiratli H, Soylemezoglu F, Bilgic S (2007) Clinicopathological parameters and expression of P-glycoprotein and MRP-1 in retinoblastoma. Ophthalmic Res 39:191-197. doi: 10.1159/ 000104680
41. Wilson MW, Fraga CH, Fuller CE, Rodriguez-Galindo C, Mancini J, Hagedorn N, Leggas ML, Stewart CF (2006) Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleation. Invest Ophthalmol Vis Sci 47:1269-1273. doi: 10.1167/iovs.05-1321
42. Minderman H, Vanhoefer U, Toth K, Yin MB, Minderman MD, Wrzosek C, Slovak ML, Rustum YM (1996) DiOC2(3) is not a substrate for multidrug resistance protein (MRP)-mediated drug efflux. Cytometry 25:14-20. doi: 10.1002/(SICI)1097-0320(19960901)25:1<14::AID-CYTO2>3.0.CO;2-E
43. Seigel GM, Hackam AS, Ganguly A, Mandell LM, Gonzalez-Fernandez F (2007) Human embryonic and neuronal stem cell markers in retinoblastoma. Mol Vis 13:823-832
44. Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, Sorrentino BP (2001) The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7:1028-1034. doi: 10.1038/nm0901-1028
45. Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M (1998) A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res 58:5337-5339