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Volumn , Issue , 2011, Pages 535-558

Molecular signatures as cancer biomarkers: Methodologic issues in discovery, validation, qualification, and standardization

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EID: 84895323471     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (3)

References (108)
  • 2
    • 24644490720 scopus 로고    scopus 로고
    • Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S. Preventive Services Task Force
    • Nelson HD, Huffman LH, Fu R, Harris EL (2005) Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S. Preventive Services Task Force. Ann. Intern. Med. 143: 362-379.
    • (2005) Ann. Intern. Med. , vol.143 , pp. 362-379
    • Nelson, H.D.1    Huffman, L.H.2    Fu, R.3    Harris, E.L.4
  • 3
    • 63049108452 scopus 로고    scopus 로고
    • Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment
    • Venkitaraman AR (2009) Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Annu. Rev. Pathol. 4: 461-487.
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 461-487
    • Venkitaraman, A.R.1
  • 4
    • 70349148223 scopus 로고    scopus 로고
    • Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model
    • Lynch HT, Lynch JF, Attard TA (2009) Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model. CMAJ 181: 273-280.
    • (2009) CMAJ , vol.181 , pp. 273-280
    • Lynch, H.T.1    Lynch, J.F.2    Attard, T.A.3
  • 5
    • 0036320522 scopus 로고    scopus 로고
    • Cancer biomarkers: easier said than done
    • Pritzker KPH (2002) Cancer biomarkers: easier said than done. Clin. Chem. 48: 1147-1150.
    • (2002) Clin. Chem. , vol.48 , pp. 1147-1150
    • Pritzker, K.P.H.1
  • 6
    • 3042687246 scopus 로고    scopus 로고
    • Genomic biomarkers for cancer assessment: implementation challenges for laboratory practice
    • Pritzker KPH, Azad A (2004) Genomic biomarkers for cancer assessment: implementation challenges for laboratory practice. Clin. Biochem. 37: 642-646.
    • (2004) Clin. Biochem. , vol.37 , pp. 642-646
    • Pritzker, K.P.H.1    Azad, A.2
  • 8
    • 0025157836 scopus 로고
    • No correlation between tumor markers and prognosis under polygenic control systems
    • Chigira M, Shinozaki T, Shimizu T, Noda K (1990) No correlation between tumor markers and prognosis under polygenic control systems. MedHypotheses 32: 245-247.
    • (1990) MedHypotheses , vol.32 , pp. 245-247
    • Chigira, M.1    Shinozaki, T.2    Shimizu, T.3    Noda, K.4
  • 9
    • 0025280917 scopus 로고
    • The significance of biological heterogeneity
    • Rubin H (1990) The significance of biological heterogeneity. Cancer Metastasis Rev. 9: 1-20.
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 1-20
    • Rubin, H.1
  • 10
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group B
    • Biomarkers Definitions Working Group B (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 69: 89-95.
    • (2001) Clin. Pharmacol. Ther. , vol.69 , pp. 89-95
  • 11
    • 0035988620 scopus 로고    scopus 로고
    • The promise of biomarkers in cancer screening and detection
    • Negm RS, Verma M, Srivastava S (2002) The promise of biomarkers in cancer screening and detection. Trends Mol. Med. 8: 288-293.
    • (2002) Trends Mol. Med. , vol.8 , pp. 288-293
    • Negm, R.S.1    Verma, M.2    Srivastava, S.3
  • 12
    • 33845974419 scopus 로고    scopus 로고
    • Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs
    • Wagner JA, Williams SA, Webster CJ (2007) Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs. Clin. Pharmacol. Ther. 81: 104-107.
    • (2007) Clin. Pharmacol. Ther. , vol.81 , pp. 104-107
    • Wagner, J.A.1    Williams, S.A.2    Webster, C.J.3
  • 13
    • 62849111680 scopus 로고    scopus 로고
    • Biomarker discovery: validation and decision-making in product development
    • Niedbala RS, Mauck C, Harrison P, Doncel GF (2009) Biomarker discovery: validation and decision-making in product development. Sex Transm. Dis. 36: S76-80.
    • (2009) Sex Transm. Dis. , vol.36 , pp. 76-80
    • Niedbala, R.S.1    Mauck, C.2    Harrison, P.3    Doncel, G.F.4
  • 14
    • 0024510707 scopus 로고
    • A conceptual framework for the validation and use of biologic markers
    • Schulte PA (1989) A conceptual framework for the validation and use of biologic markers. Environ. Res. 48: 129-144.
    • (1989) Environ. Res. , vol.48 , pp. 129-144
    • Schulte, P.A.1
  • 15
    • 1942438016 scopus 로고    scopus 로고
    • Rules of evidence for cancer molecular-marker discovery and validation
    • Ransohoff DF (2004) Rules of evidence for cancer molecular-marker discovery and validation. Nat. Rev. Cancer 4: 309-314.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 309-314
    • Ransohoff, D.F.1
  • 16
    • 58149154725 scopus 로고    scopus 로고
    • Validation of analytic methods for biomarkers used in drug development
    • Chau CH, Rixe O, McLeod H, Figg WD (2008) Validation of analytic methods for biomarkers used in drug development. Clin. Cancer Res. 14: 5967-5976.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5967-5976
    • Chau, C.H.1    Rixe, O.2    McLeod, H.3    Figg, W.D.4
  • 17
    • 35348814333 scopus 로고    scopus 로고
    • Development and Validation of Biomarker Classifiers for Treatment Selection
    • Simon R (2008) Development and Validation of Biomarker Classifiers for Treatment Selection. J. Stat. Plan Inference 138: 308-320.
    • (2008) J. Stat. Plan Inference , vol.138 , pp. 308-320
    • Simon, R.1
  • 19
    • 0031000842 scopus 로고    scopus 로고
    • An approach to the validation of markers for use in AIDS clinical trials
    • Mildvan D, Landay A, De GV, Machado SG, Kagan J (1997) An approach to the validation of markers for use in AIDS clinical trials. ClinInfectDis. 24: 764-774.
    • (1997) ClinInfectDis. , vol.24 , pp. 764-774
    • Mildvan, D.1    Landay, A.2    De, G.V.3    Machado, S.G.4    Kagan, J.5
  • 21
    • 34247391164 scopus 로고    scopus 로고
    • Role of tumor markers in patients with solid cancers: A critical review
    • Duffy MJ (2007) Role of tumor markers in patients with solid cancers: A critical review. Eur. J. Intern. Med. 18: 175-184.
    • (2007) Eur. J. Intern. Med. , vol.18 , pp. 175-184
    • Duffy, M.J.1
  • 22
    • 0026598740 scopus 로고
    • Multivariate analysis of serum tumor markers for diagnosis of skeletal metastases
    • Shinozaki T, Chigira M, Kato K (1992) Multivariate analysis of serum tumor markers for diagnosis of skeletal metastases. Cancer 69: 108-112.
    • (1992) Cancer , vol.69 , pp. 108-112
    • Shinozaki, T.1    Chigira, M.2    Kato, K.3
  • 25
    • 44649122151 scopus 로고    scopus 로고
    • Role of histone modifications in defining chromatin structure and function
    • Gelato KA, Fischle W (2008) Role of histone modifications in defining chromatin structure and function. Biol. Chem. 389: 353-363.
    • (2008) Biol. Chem. , vol.389 , pp. 353-363
    • Gelato, K.A.1    Fischle, W.2
  • 26
    • 0142062911 scopus 로고    scopus 로고
    • MLL-rearranged leukemias: insights from gene expression profiling
    • Armstrong SA, Golub TR, Korsmeyer SJ (2003) MLL-rearranged leukemias: insights from gene expression profiling. Semin. Hematol. 40: 268-273.
    • (2003) Semin. Hematol. , vol.40 , pp. 268-273
    • Armstrong, S.A.1    Golub, T.R.2    Korsmeyer, S.J.3
  • 27
    • 0037409182 scopus 로고    scopus 로고
    • The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease
    • Mistry AR, Pedersen EW, Solomon E, Grimwade D (2003) The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease. Blood Rev. 17: 71-97.
    • (2003) Blood Rev. , vol.17 , pp. 71-97
    • Mistry, A.R.1    Pedersen, E.W.2    Solomon, E.3    Grimwade, D.4
  • 28
    • 0036386359 scopus 로고    scopus 로고
    • Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation
    • Lehrmann H, Pritchard LL, Harel-Bellan A (2002) Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation. Adv. Cancer Res. 86: 41-65.
    • (2002) Adv. Cancer Res. , vol.86 , pp. 41-65
    • Lehrmann, H.1    Pritchard, L.L.2    Harel-Bellan, A.3
  • 29
    • 59149084542 scopus 로고    scopus 로고
    • Targeted proteomic strategy for clinical biomarker discovery
    • Schiess R, Wollscheid B, Aebersold R (2009) Targeted proteomic strategy for clinical biomarker discovery. Mol. Oncol. 3: 33-44.
    • (2009) Mol. Oncol. , vol.3 , pp. 33-44
    • Schiess, R.1    Wollscheid, B.2    Aebersold, R.3
  • 30
    • 58849143465 scopus 로고    scopus 로고
    • DNA methylation markers predict outcome in node-positive, estrogen receptor-positive breast cancer with adjuvant anthracycline-based chemotherapy
    • Hartmann O, Spyratos F, Harbeck N, Dietrich D, Fassbender A, et al. (2009) DNA methylation markers predict outcome in node-positive, estrogen receptor-positive breast cancer with adjuvant anthracycline-based chemotherapy. Clin. Cancer Res. 15: 315-323.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 315-323
    • Hartmann, O.1    Spyratos, F.2    Harbeck, N.3    Dietrich, D.4    Fassbender, A.5
  • 31
    • 68949170824 scopus 로고    scopus 로고
    • Predicting favourable prognosis of urothelial carcinoma: gene expression and genome profiling
    • van der Kwast TH, Bapat B
    • van der Kwast TH, Bapat B (2009) Predicting favourable prognosis of urothelial carcinoma: gene expression and genome profiling. Curr. Opin. Urol. 19: 516-521.
    • (2009) Curr. Opin. Urol. , vol.19 , pp. 516-521
  • 32
    • 59849125136 scopus 로고    scopus 로고
    • Dynamic modularity in protein interaction networks predicts breast cancer outcome
    • Taylor IW, Linding R, Warde-Farley D, Liu Y, Pesquita C, et al. (2009) Dynamic modularity in protein interaction networks predicts breast cancer outcome. Nat. Biotechnol. 27: 199-204.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 199-204
    • Taylor, I.W.1    Linding, R.2    Warde-Farley, D.3    Liu, Y.4    Pesquita, C.5
  • 33
    • 67449132037 scopus 로고    scopus 로고
    • Optimizing molecular signatures for predicting prostate cancer recurrence
    • Sun Y, Goodison S (2009) Optimizing molecular signatures for predicting prostate cancer recurrence. Prostate 69: 1119-1127.
    • (2009) Prostate , vol.69 , pp. 1119-1127
    • Sun, Y.1    Goodison, S.2
  • 34
    • 32544451155 scopus 로고    scopus 로고
    • Fit-for-purpose method development and validation for successful biomarker measurement
    • Lee JW, Devanarayan V, Barrett YC, Weiner R, Allinson J, et al. (2006) Fit-for-purpose method development and validation for successful biomarker measurement. Pharm. Res. 23: 312-328.
    • (2006) Pharm. Res. , vol.23 , pp. 312-328
    • Lee, J.W.1    Devanarayan, V.2    Barrett, Y.C.3    Weiner, R.4    Allinson, J.5
  • 35
    • 0034802767 scopus 로고    scopus 로고
    • Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop
    • De Gruttola VG, Clax P, DeMets DL, Downing GJ, Ellenberg SS, et al. (2001) Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop. Control ClinTrials 22: 485-502.
    • (2001) Control ClinTrials , vol.22 , pp. 485-502
    • De Gruttola, V.G.1    Clax, P.2    DeMets, D.L.3    Downing, G.J.4    Ellenberg, S.S.5
  • 36
    • 58149145635 scopus 로고    scopus 로고
    • Validation of biomarker-based risk prediction models
    • Taylor JM, Ankerst DP, Andridge RR (2008) Validation of biomarker-based risk prediction models. Clin. Cancer Res. 14: 5977-5983.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5977-5983
    • Taylor, J.M.1    Ankerst, D.P.2    Andridge, R.R.3
  • 37
    • 77449105717 scopus 로고    scopus 로고
    • An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer
    • Bild AH, Parker JS, Gustafson AM, Acharya CR, Hoadley KA, et al. (2009) An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer. Breast Cancer Res 11: R55.
    • (2009) Breast Cancer Res , vol.11 , pp. 55
    • Bild, A.H.1    Parker, J.S.2    Gustafson, A.M.3    Acharya, C.R.4    Hoadley, K.A.5
  • 38
    • 42449155116 scopus 로고    scopus 로고
    • Early detection of colon cancer: new tests on the horizon
    • Gupta AK, Brenner DE, Turgeon DK (2008) Early detection of colon cancer: new tests on the horizon. Mol. Diagn. Ther. 12: 77-85.
    • (2008) Mol. Diagn. Ther. , vol.12 , pp. 77-85
    • Gupta, A.K.1    Brenner, D.E.2    Turgeon, D.K.3
  • 39
    • 67650091465 scopus 로고    scopus 로고
    • The search for new prostate cancer biomarkers continues
    • Pavlou M, Diamandis EP (2009) The search for new prostate cancer biomarkers continues. Clin. Chem. 55: 1277-1279.
    • (2009) Clin. Chem. , vol.55 , pp. 1277-1279
    • Pavlou, M.1    Diamandis, E.P.2
  • 41
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L (2009) Gene-expression signatures in breast cancer. N. Engl. J. Med. 360: 790-800.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 42
    • 58149357365 scopus 로고    scopus 로고
    • Genome-wide association studies in cancer
    • Easton DF, Eeles RA (2008) Genome-wide association studies in cancer. Hum. Mol. Genet. 17: R109-115.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 109-115
    • Easton, D.F.1    Eeles, R.A.2
  • 44
    • 60749085623 scopus 로고    scopus 로고
    • Analytical validation of the GeXP analyzer and design of a workflow for cancer-biomarker discovery using multiplexed gene-expression profiling
    • Rai AJ, Kamath RM, Gerald W, Fleisher M (2009) Analytical validation of the GeXP analyzer and design of a workflow for cancer-biomarker discovery using multiplexed gene-expression profiling. Anal. Bioanal. Chem. 393: 1505-1511.
    • (2009) Anal. Bioanal. Chem. , vol.393 , pp. 1505-1511
    • Rai, A.J.1    Kamath, R.M.2    Gerald, W.3    Fleisher, M.4
  • 45
    • 71449125258 scopus 로고    scopus 로고
    • Altered Expression of Proliferation-Inducing and Proliferation-Inhibiting Genes Might Contribute to Acquired Doxorubicin Resistance in Breast Cancer Cells
    • Saleh EM, El-Awady RA, Abdel Alim MA, Abdel Wahab AH (2009) Altered Expression of Proliferation-Inducing and Proliferation-Inhibiting Genes Might Contribute to Acquired Doxorubicin Resistance in Breast Cancer Cells. Cell Biochem.
    • (2009) Cell Biochem.
    • Saleh, E.M.1    El-Awady, R.A.2    Abdel Alim, M.A.3    Abdel Wahab, A.H.4
  • 47
    • 20144368638 scopus 로고    scopus 로고
    • Integrated genomic and proteomic analyses of gene expression in Mammalian cells
    • Tian Q, Stepaniants SB, Mao M, Weng L, Feetham MC, et al. (2004) Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mol. Cell Proteomics 3: 960-969.
    • (2004) Mol. Cell Proteomics , vol.3 , pp. 960-969
    • Tian, Q.1    Stepaniants, S.B.2    Mao, M.3    Weng, L.4    Feetham, M.C.5
  • 48
    • 33646336623 scopus 로고    scopus 로고
    • Rapid and multiplexed transcript analysis of microbial cultures using capillary electophoresis-detectable oligonucleotide probe pools
    • Rautio JJ, Kataja K, Satokari R, Penttila M, Soderlund H, et al. (2006) Rapid and multiplexed transcript analysis of microbial cultures using capillary electophoresis-detectable oligonucleotide probe pools. J. Microbiol. Methods 65: 404-416.
    • (2006) J. Microbiol. Methods , vol.65 , pp. 404-416
    • Rautio, J.J.1    Kataja, K.2    Satokari, R.3    Penttila, M.4    Soderlund, H.5
  • 49
    • 61749101333 scopus 로고    scopus 로고
    • Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis
    • Estilo CL, P Oc, Talbot S, Socci ND, Carlson DL, et al. (2009) Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis. BMC Cancer 9: 11.
    • (2009) BMC Cancer , vol.9 , pp. 11
    • Estilo, C.L.1    Oc, P.2    Talbot, S.3    Socci, N.D.4    Carlson, D.L.5
  • 51
    • 64649084247 scopus 로고    scopus 로고
    • Development of high-throughput mass spectrometry-based approaches for cancer biomarker discovery and implementation
    • Hood BL, Stewart NA, Conrads TP (2009) Development of high-throughput mass spectrometry-based approaches for cancer biomarker discovery and implementation. Clin. Lab. Med. 29: 115-138.
    • (2009) Clin. Lab. Med. , vol.29 , pp. 115-138
    • Hood, B.L.1    Stewart, N.A.2    Conrads, T.P.3
  • 52
    • 67650467358 scopus 로고    scopus 로고
    • Biomarker validation by targeted mass spectrometry
    • McIntosh M, Fitzgibbon M (2009) Biomarker validation by targeted mass spectrometry. Nat. Biotechnol. 27: 622-623.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 622-623
    • McIntosh, M.1    Fitzgibbon, M.2
  • 53
    • 64149101160 scopus 로고    scopus 로고
    • Quantitative mass spectrometry-based techniques for clinical use: biomarker identification and quantification
    • Simpson KL, Whetton AD, Dive C (2009) Quantitative mass spectrometry-based techniques for clinical use: biomarker identification and quantification. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877: 1240-1249.
    • (2009) J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. , vol.877 , pp. 1240-1249
    • Simpson, K.L.1    Whetton, A.D.2    Dive, C.3
  • 54
    • 67449135223 scopus 로고    scopus 로고
    • An integrative multi-platform analysis for discovering biomarkers of osteosarcoma
    • Li G, Zhang W, Zeng H, Chen L, Wang W, et al. (2009) An integrative multi-platform analysis for discovering biomarkers of osteosarcoma. BMC Cancer 9: 150.
    • (2009) BMC Cancer , vol.9 , pp. 150
    • Li, G.1    Zhang, W.2    Zeng, H.3    Chen, L.4    Wang, W.5
  • 55
    • 64949109360 scopus 로고    scopus 로고
    • The use of laser microdissection and SELDI-TOF MS in ovarian cancer tissue to identify protein profiles
    • Cadron I, Van Gorp T, Amant F, Vergote I, Moerman P, et al. (2009) The use of laser microdissection and SELDI-TOF MS in ovarian cancer tissue to identify protein profiles. Anticancer Res. 29: 1039-1045.
    • (2009) Anticancer Res. , vol.29 , pp. 1039-1045
    • Cadron, I.1    Van Gorp, T.2    Amant, F.3    Vergote, I.4    Moerman, P.5
  • 56
    • 63049132403 scopus 로고    scopus 로고
    • Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma
    • Seliger B, Dressler SP, Wang E, Kellner R, Recktenwald CV, et al. (2009) Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics 9: 1567-1581.
    • (2009) Proteomics , vol.9 , pp. 1567-1581
    • Seliger, B.1    Dressler, S.P.2    Wang, E.3    Kellner, R.4    Recktenwald, C.V.5
  • 57
    • 3342964832 scopus 로고    scopus 로고
    • Classification in microarray experiments
    • Speed T, (editor.), New York: Chapman and Hall, CRC Press
    • Dudoit S, Fridlyand J (2003) Classification in microarray experiments. In: Speed T, (editor.) Statistical Analysis of Gene Expression Microarray Data. New York: Chapman and Hall, CRC Press. pp. 93-158.
    • (2003) Statistical Analysis of Gene Expression Microarray Data , pp. 93-158
    • Dudoit, S.1    Fridlyand, J.2
  • 58
    • 84858278664 scopus 로고    scopus 로고
    • Derivation of molecular signatures for breast cancer recurrence prediction using a two-way validation approach
    • Sun Y, Urquidi V, Goodison S (2009) Derivation of molecular signatures for breast cancer recurrence prediction using a two-way validation approach. Breast Cancer Res.
    • (2009) Breast Cancer Res.
    • Sun, Y.1    Urquidi, V.2    Goodison, S.3
  • 59
    • 0034970054 scopus 로고    scopus 로고
    • Standardization, analytical validation, and quality control of intermediate endpoint biomarkers
    • Veltri RW, Miller MC, An G (2001) Standardization, analytical validation, and quality control of intermediate endpoint biomarkers. Urology 57: 164-170.
    • (2001) Urology , vol.57 , pp. 164-170
    • Veltri, R.W.1    Miller, M.C.2    An, G.3
  • 60
    • 67349139274 scopus 로고    scopus 로고
    • Validation of serum biomarkers for detection of early-stage ovarian cancer
    • Nosov V, Su F, Amneus M, Birrer M, Robins T, et al. (2009) Validation of serum biomarkers for detection of early-stage ovarian cancer. Am. J. Obstet. Gynecol. 200: 639 e631-635.
    • (2009) Am. J. Obstet. Gynecol. , vol.200
    • Nosov, V.1    Su, F.2    Amneus, M.3    Birrer, M.4    Robins, T.5
  • 61
    • 0035066943 scopus 로고    scopus 로고
    • Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumors
    • Hoos A, Urist MJ, Stojadinovic A, Mastorides S, Dudas ME, et al. (2001) Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumors. Am. J. Pathol. 158: 1245-1251.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1245-1251
    • Hoos, A.1    Urist, M.J.2    Stojadinovic, A.3    Mastorides, S.4    Dudas, M.E.5
  • 62
    • 65649137308 scopus 로고    scopus 로고
    • Tissue microarrays as a tool in the discovery and validation of tumor markers
    • Hewitt SM (2009) Tissue microarrays as a tool in the discovery and validation of tumor markers. Methods Mol. Biol. 520: 151-161.
    • (2009) Methods Mol. Biol. , vol.520 , pp. 151-161
    • Hewitt, S.M.1
  • 63
    • 57149117848 scopus 로고    scopus 로고
    • A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers
    • Camp RL, Neumeister V, Rimm DL (2008) A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers. J. Clin. Oncol. 26: 5630-5637.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5630-5637
    • Camp, R.L.1    Neumeister, V.2    Rimm, D.L.3
  • 64
    • 62349116490 scopus 로고    scopus 로고
    • Microarray methods to identify factors determining breast cancer progression: potentials, limitations, and challenges
    • van der Vegt B, de Bock GH, Hollema H, Wesseling J (2009) Microarray methods to identify factors determining breast cancer progression: potentials, limitations, and challenges. Crit. Rev. Oncol. Hematol. 70: 1-11.
    • (2009) Crit. Rev. Oncol. Hematol. , vol.70 , pp. 1-11
    • van der Vegt, B.1    de Bock, G.H.2    Hollema, H.3    Wesseling, J.4
  • 65
    • 68149132981 scopus 로고    scopus 로고
    • Towards improved cancer diagnosis and prognosis using analysis of gene expression data and computer aided imaging
    • (Maywood)
    • Lexe G, Monaco J, Doyle S, Basavanhally A, Reddy A, et al. (2009) Towards improved cancer diagnosis and prognosis using analysis of gene expression data and computer aided imaging. Exp. Biol. Med. (Maywood) 234: 860-879.
    • (2009) Exp. Biol. Med. , vol.234 , pp. 860-879
    • Lexe, G.1    Monaco, J.2    Doyle, S.3    Basavanhally, A.4    Reddy, A.5
  • 67
    • 84887212455 scopus 로고    scopus 로고
    • Cross-study projections of genomic biomarkers: an evaluation in cancer genomics
    • Lucas JE, Carvalho CM, Chen JL, Chi JT, West M (2009) Cross-study projections of genomic biomarkers: an evaluation in cancer genomics. PLoS One 4: e4523.
    • (2009) PLoS One , vol.4 , pp. 4523
    • Lucas, J.E.1    Carvalho, C.M.2    Chen, J.L.3    Chi, J.T.4    West, M.5
  • 68
    • 63849148854 scopus 로고    scopus 로고
    • A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer
    • Reyal F, van Vliet MH, Armstrong NJ, Horlings HM, de Visser KE, et al. (2008) A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer. Breast Cancer Res. 10: R93.
    • (2008) Breast Cancer Res. , vol.10 , pp. 93
    • Reyal, F.1    van Vliet, M.H.2    Armstrong, N.J.3    Horlings, H.M.4    de Visser, K.E.5
  • 70
    • 0036399255 scopus 로고    scopus 로고
    • Overview of biomarkers and surrogate endpoints in drug development
    • Wagner JA (2002) Overview of biomarkers and surrogate endpoints in drug development. Dis. Markers 18: 41-46.
    • (2002) Dis. Markers , vol.18 , pp. 41-46
    • Wagner, J.A.1
  • 71
    • 67651030311 scopus 로고    scopus 로고
    • Clinical trial designs for predictive biomarker validation: one size does not fit all
    • Mandrekar SJ, Sargent DJ (2009) Clinical trial designs for predictive biomarker validation: one size does not fit all. J. Biopharm. Stat. 19: 530-542.
    • (2009) J. Biopharm. Stat. , vol.19 , pp. 530-542
    • Mandrekar, S.J.1    Sargent, D.J.2
  • 72
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, et al. (2001) Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344: 783-792.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3    Fuchs, H.4    Paton, V.5
  • 73
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D, Gutheil JC, Harris LN, et al. (2002) Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 20: 719-726.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3    Gutheil, J.C.4    Harris, L.N.5
  • 74
    • 62449153701 scopus 로고    scopus 로고
    • The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells
    • Wu X, Hawse JR, Subramaniam M, Goetz MP, Ingle JN, et al. (2009) The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells. Cancer Res. 69: 1722-1727.
    • (2009) Cancer Res. , vol.69 , pp. 1722-1727
    • Wu, X.1    Hawse, J.R.2    Subramaniam, M.3    Goetz, M.P.4    Ingle, J.N.5
  • 75
    • 34147103980 scopus 로고    scopus 로고
    • The role of KIT in the management of patients with gastrointestinal stromal tumors
    • Hornick JL, Fletcher CD (2007) The role of KIT in the management of patients with gastrointestinal stromal tumors. Hum. Pathol. 38: 679-687.
    • (2007) Hum. Pathol. , vol.38 , pp. 679-687
    • Hornick, J.L.1    Fletcher, C.D.2
  • 77
    • 49749122255 scopus 로고    scopus 로고
    • Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours
    • Lasota J, Miettinen M (2008) Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology 53: 245-266.
    • (2008) Histopathology , vol.53 , pp. 245-266
    • Lasota, J.1    Miettinen, M.2
  • 78
    • 59849123146 scopus 로고    scopus 로고
    • FDA holds court on post hoc data linking KRAS status to drug response
    • Mack GS (2009) FDA holds court on post hoc data linking KRAS status to drug response. Nat. Biotechnol. 27: 110-112.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 110-112
    • Mack, G.S.1
  • 79
    • 49449107381 scopus 로고    scopus 로고
    • EGFR inhibitors embrace KRAS
    • Sheridan C (2008) EGFR inhibitors embrace KRAS. Nat. Biotechnol. 26: 839-840.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 839-840
    • Sheridan, C.1
  • 80
    • 38649099966 scopus 로고    scopus 로고
    • KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
    • Lievre A, Bachet JB, Boige V, Cayre A, Le Corre D, et al. (2008) KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J. Clin. Oncol. 26: 374-379.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 374-379
    • Lievre, A.1    Bachet, J.B.2    Boige, V.3    Cayre, A.4    Le Corre, D.5
  • 81
    • 45149084723 scopus 로고    scopus 로고
    • First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
    • Sequist LV, Martins RG, Spigel D, Grunberg SM, Spira A, et al. (2008) First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J. Clin. Oncol. 26: 2442-2449.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2442-2449
    • Sequist, L.V.1    Martins, R.G.2    Spigel, D.3    Grunberg, S.M.4    Spira, A.5
  • 82
    • 45949083997 scopus 로고    scopus 로고
    • A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment
    • Goncalves A, Esteyries S, Taylor-Smedra B, Lagarde A, Ayadi M, et al. (2008) A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer 8: 169.
    • (2008) BMC Cancer , vol.8 , pp. 169
    • Goncalves, A.1    Esteyries, S.2    Taylor-Smedra, B.3    Lagarde, A.4    Ayadi, M.5
  • 83
    • 0037254419 scopus 로고    scopus 로고
    • Imatinib alone and in combination for chronic myeloid leukemia
    • Druker BJ (2003) Imatinib alone and in combination for chronic myeloid leukemia. Semin. Hematol. 40: 50-58.
    • (2003) Semin. Hematol. , vol.40 , pp. 50-58
    • Druker, B.J.1
  • 84
    • 0038439275 scopus 로고    scopus 로고
    • Cytogenetic studies in patients on imatinib
    • Deininger MW (2003) Cytogenetic studies in patients on imatinib. Semin. Hematol. 40: 50-55.
    • (2003) Semin. Hematol. , vol.40 , pp. 50-55
    • Deininger, M.W.1
  • 85
    • 33846849302 scopus 로고    scopus 로고
    • New targeted therapies for chronic myelogenous leukemia: opportunities to overcome imatinib resistance
    • Jabbour E, Cortes J, O'Brien S, Giles F, Kantarjian H (2007) New targeted therapies for chronic myelogenous leukemia: opportunities to overcome imatinib resistance. Semin. Hematol. 44: S25-31.
    • (2007) Semin. Hematol. , vol.44 , pp. 25-31
    • Jabbour, E.1    Cortes, J.2    O'Brien, S.3    Giles, F.4    Kantarjian, H.5
  • 86
    • 57649126380 scopus 로고    scopus 로고
    • Treatment of adult acute lymphoblastic leukemia
    • Gokbuget N, Hoelzer D (2009) Treatment of adult acute lymphoblastic leukemia. Semin. Hematol. 46: 64-75.
    • (2009) Semin. Hematol. , vol.46 , pp. 64-75
    • Gokbuget, N.1    Hoelzer, D.2
  • 87
    • 33748693297 scopus 로고    scopus 로고
    • Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
    • Buyse M, Loi S, van't Veer L, Viale G, Delorenzi M, et al. (2006) Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J. Natl. Cancer Inst. 98: 1183-1192.
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 1183-1192
    • Buyse, M.1    Loi, S.2    van't Veer, L.3    Viale, G.4    Delorenzi, M.5
  • 89
    • 33744814477 scopus 로고    scopus 로고
    • Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer
    • Paik S, Tang G, Shak S, Kim C, Baker J, et al. (2006) Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J. Clin. Oncol. 24: 3726-3734.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3726-3734
    • Paik, S.1    Tang, G.2    Shak, S.3    Kim, C.4    Baker, J.5
  • 90
    • 59849127767 scopus 로고    scopus 로고
    • Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer?
    • EGAPP
    • EGAPP (2009) Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer? Genet. Med. 11: 66-73.
    • (2009) Genet. Med. , vol.11 , pp. 66-73
  • 91
    • 58049212010 scopus 로고    scopus 로고
    • Determination of HER2 amplification by in situ hybridization: when should chromosome 17 also be determined?
    • Bartlett JM, Campbell FM, Mallon EA (2008) Determination of HER2 amplification by in situ hybridization: when should chromosome 17 also be determined? Am. J. Clin. Pathol. 130: 920-926.
    • (2008) Am. J. Clin. Pathol. , vol.130 , pp. 920-926
    • Bartlett, J.M.1    Campbell, F.M.2    Mallon, E.A.3
  • 92
    • 61349131323 scopus 로고    scopus 로고
    • Prediction of HER2 gene status in Her2 2+ invasive breast cancer: a study of 108 cases comparing ASCO/CAP and FDA recommendations
    • Chibon F, de Mascarel I, Sierankowski G, Brouste V, Bonnefoi H, et al. (2009) Prediction of HER2 gene status in Her2 2+ invasive breast cancer: a study of 108 cases comparing ASCO/CAP and FDA recommendations. Mod. Pathol. 22: 403-409.
    • (2009) Mod. Pathol. , vol.22 , pp. 403-409
    • Chibon, F.1    de Mascarel, I.2    Sierankowski, G.3    Brouste, V.4    Bonnefoi, H.5
  • 93
    • 84895271216 scopus 로고    scopus 로고
    • Advancing breast cancer HER2 FISH quality by image analysis (abstract) 2009 December 9-13, San Antonio, Texas, USA
    • Rogers M, Dore JH, Grunkin M, Pritzker KPH. Advancing breast cancer HER2 FISH quality by image analysis (abstract) 2009 December 9-13, 2009; San Antonio, Texas, USA.
    • (2009)
    • Rogers, M.1    Dore, J.H.2    Grunkin, M.3    Pritzker, K.P.H.4
  • 95
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, et al. (2007) The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res Treat 101: 113-121.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 113-121
    • Goetz, M.P.1    Knox, S.K.2    Suman, V.J.3    Rae, J.M.4    Safgren, S.L.5
  • 96
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V, Ward B, Ho H, et al. (2005) CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J. Natl. Cancer Inst. 97: 30-39.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3    Ward, B.4    Ho, H.5
  • 97
    • 44049098379 scopus 로고    scopus 로고
    • Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis
    • Punglia RS, Burstein HJ, Winer EP, Weeks JC (2008) Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis. J. Natl. Cancer Inst. 100: 642-648.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 642-648
    • Punglia, R.S.1    Burstein, H.J.2    Winer, E.P.3    Weeks, J.C.4
  • 98
    • 33745699885 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer
    • Girault I, Bieche I, Lidereau R (2006) Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer. Maturitas 54: 342-351.
    • (2006) Maturitas , vol.54 , pp. 342-351
    • Girault, I.1    Bieche, I.2    Lidereau, R.3
  • 100
    • 58149263311 scopus 로고    scopus 로고
    • TSC22D1 and PSAP predict clinical outcome of tamoxifen treatment in patients with recurrent breast cancer
    • Meijer D, Jansen MP, Look MP, Ruigrok-Ritstier K, van Staveren IL, et al. (2009) TSC22D1 and PSAP predict clinical outcome of tamoxifen treatment in patients with recurrent breast cancer. Breast Cancer Res. Treat. 113: 253-260.
    • (2009) Breast Cancer Res. Treat. , vol.113 , pp. 253-260
    • Meijer, D.1    Jansen, M.P.2    Look, M.P.3    Ruigrok-Ritstier, K.4    van Staveren, I.L.5
  • 101
    • 0034889448 scopus 로고    scopus 로고
    • Tumor markers in the laboratory: closing the guideline-practice gap
    • Sturgeon CM (2001) Tumor markers in the laboratory: closing the guideline-practice gap. Clin. Biochem. 34: 353-359.
    • (2001) Clin. Biochem. , vol.34 , pp. 353-359
    • Sturgeon, C.M.1
  • 103
    • 84895300614 scopus 로고    scopus 로고
    • CAP, Laboratory-developed test oversight model
    • CAP (2009) Laboratory-developed test oversight model.
    • (2009)
  • 104
    • 70349644851 scopus 로고    scopus 로고
    • The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer
    • Monzon FA, Ogino S, Hammond ME, Halling KC, Bloom KJ, et al. (2009) The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer. Arch. Pathol. Lab. Med. 133: 1600-1606.
    • (2009) Arch. Pathol. Lab. Med. , vol.133 , pp. 1600-1606
    • Monzon, F.A.1    Ogino, S.2    Hammond, M.E.3    Halling, K.C.4    Bloom, K.J.5
  • 105
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: a review
    • Bos JL (1989) ras oncogenes in human cancer: a review. Cancer Res. 49: 4682-4689.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 106
    • 0032438455 scopus 로고    scopus 로고
    • Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients
    • Ko JM, Cheung MH, Wong CM, Lau KW, Tang CM, et al. (1998) Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients. Cancer Lett. 134: 169-176.
    • (1998) Cancer Lett. , vol.134 , pp. 169-176
    • Ko, J.M.1    Cheung, M.H.2    Wong, C.M.3    Lau, K.W.4    Tang, C.M.5
  • 107
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • Lievre A, Bachet JB, Le Corre D, Boige V, Landi B, et al. (2006) KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. 66: 3992-3995.
    • (2006) Cancer Res. , vol.66 , pp. 3992-3995
    • Lievre, A.1    Bachet, J.B.2    Le Corre, D.3    Boige, V.4    Landi, B.5
  • 108
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, et al. (2009) American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J. Clin. Oncol. 27: 2091-2096.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3    Hamilton, S.R.4    Hammond, E.H.5


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