-
1
-
-
34547852275
-
Progress and promise: Highlights of the international expert consensus on the primary therapy of early breast cancer 2007
-
Goldhirsch A, Wood WC, Gelber RD, et al. Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007 Ann Oncol 2007; 18:1133-44.
-
(2007)
Ann Oncol
, vol.18
, pp. 1133-1144
-
-
Goldhirsch, A.1
Wood, W.C.2
Gelber, R.D.3
-
2
-
-
50249110527
-
Extended follow-up and analysis by age of the US Oncology Adjuvant trial 9735: Docetaxel/ cyclophosphamide is associated with an overall survival benefit compared to doxorubicin /cyclophosphamide and is well-tolerated in women 65 or older
-
Jones S, Holmes F, O'Shaughnessy J, et al. Extended follow-up and analysis by age of the US Oncology Adjuvant trial 9735: docetaxel/ cyclophosphamide is associated with an overall survival benefit compared to doxorubicin /cyclophosphamide and is well-tolerated in women 65 or older. San Antonio Breast Cancer Meeting 2007.
-
(2007)
San Antonio Breast Cancer Meeting
-
-
Jones, S.1
Holmes, F.2
O'Shaughnessy, J.3
-
3
-
-
33646703775
-
Anthracyclines and the tailoring of treatment for early breast cancer
-
Piccart-Gebhart MJ. Anthracyclines and the tailoring of treatment for early breast cancer. N Engl J Med 2006; 354:2177-9.
-
(2006)
N Engl J Med
, vol.354
, pp. 2177-2179
-
-
Piccart-Gebhart, M.J.1
-
4
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16:168-74.
-
(2000)
Trends Genet
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
5
-
-
0029898837
-
DNA methylation errors and cancer
-
Jones PA. DNA methylation errors and cancer. Cancer Res 1996; 56:2463-7.
-
(1996)
Cancer Res
, vol.56
, pp. 2463-2467
-
-
Jones, P.A.1
-
6
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003; 349:2042-54.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
7
-
-
0011964662
-
Tumour class prediction and discovery by microarray-based DNA methylation analysis
-
Adorjan P, Distler J, Lipscher E, et al. Tumour class prediction and discovery by microarray-based DNA methylation analysis. Nucleic Acids Res 2002; 30:e21.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Adorjan, P.1
Distler, J.2
Lipscher, E.3
-
8
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343:1350-4.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
9
-
-
0037005988
-
Hypermethylation of the DNA repair gene O (6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
-
Esteller M, Gaidano G, Goodman SN, et al. Hypermethylation of the DNA repair gene O (6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst 2002; 94:26-32.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 26-32
-
-
Esteller, M.1
Gaidano, G.2
Goodman, S.N.3
-
10
-
-
0043194338
-
DNA methylation patterns in cancer: Novel prognostic indicators?
-
Fruhwald MC. DNA methylation patterns in cancer: novel prognostic indicators? Am J Pharmacogenomics 2003; 3:245-60.
-
(2003)
Am J Pharmacogenomics
, vol.3
, pp. 245-260
-
-
Fruhwald, M.C.1
-
11
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003; 3:253-66.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
12
-
-
0141567525
-
The androgen receptor gene is preferentially hypermethylated in follicular non-Hodgkin's lymphomas
-
Yang H, Chen CM, Yan P, et al. The androgen receptor gene is preferentially hypermethylated in follicular non-Hodgkin's lymphomas. Clin Cancer Res 2003; 9: 4034-42.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4034-4042
-
-
Yang, H.1
Chen, C.M.2
Yan, P.3
-
13
-
-
34447262607
-
DNA-methylation of the homeodomain transcription factor PITX2 reliably predicts risk of distant disease recurrence in tamoxifen-treated, node-negative breast cancer patients-technical and clinical validation in a multicentre setting in collaboration with the European Organisation for Research and Treatment of Cancer (EORTC) Pathobiology Group
-
Maier S, Nimmrich I, KoenigT, et al. DNA-methylation of the homeodomain transcription factor PITX2 reliably predicts risk of distant disease recurrence in tamoxifen-treated, node-negative breast cancer patients-technical and clinical validation in a multicentre setting in collaboration with the European Organisation for Research and Treatment of Cancer (EORTC) Pathobiology Group. Eur J Cancer 2007; 43: 1679-86.
-
(2007)
Eur J Cancer
, vol.43
, pp. 1679-1686
-
-
Maier, S.1
Nimmrich, I.2
KoenigT3
-
14
-
-
20144365156
-
-
Martens JWM, Nimmrich I. KoenigT, et al. Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer. Cancer Res 2005; 65:4101-17.
-
Martens JWM, Nimmrich I. KoenigT, et al. Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer. Cancer Res 2005; 65:4101-17.
-
-
-
-
15
-
-
51649095103
-
DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients
-
Nimmrich I, Sieuwerts AM, Meijer-van Gelder ME, et al. DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients. Breast Cancer ResTreat 2008; 111:429-37.
-
(2008)
Breast Cancer ResTreat
, vol.111
, pp. 429-437
-
-
Nimmrich, I.1
Sieuwerts, A.M.2
Meijer-van Gelder, M.E.3
-
16
-
-
2542629617
-
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen
-
Widschwendter M, Siegmund KD, Muller HM, et al. Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Res 2004; 64:3807-13.
-
(2004)
Cancer Res
, vol.64
, pp. 3807-3813
-
-
Widschwendter, M.1
Siegmund, K.D.2
Muller, H.M.3
-
17
-
-
55549136409
-
Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients
-
Harbeck N, Nimmrich I, Hartmann A, et al. Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients. J Clin Oncol 2008; 26:5036-42.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5036-5042
-
-
Harbeck, N.1
Nimmrich, I.2
Hartmann, A.3
-
18
-
-
11244346557
-
Variance stabilization applied to microarray data calibration and to the quantification of differential expression
-
Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 2002; 18 Suppl 1: S96-104.
-
(2002)
Bioinformatics
, vol.18
, Issue.SUPPL. 1
-
-
Huber, W.1
von Heydebreck, A.2
Sultmann, H.3
Poustka, A.4
Vingron, M.5
-
21
-
-
33845382806
-
Non-parametric estimation from incomplete observations
-
Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Assoc 1958; 53:457-81.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
22
-
-
84944363874
-
Evaluating the yield of medical tests
-
Harrell FE, Jr., Califf RM, Pryor DB, Lee KL, Rosati RA, Evaluating the yield of medical tests. JAMA 1982; 247:2543-6.
-
(1982)
JAMA
, vol.247
, pp. 2543-2546
-
-
Harrell Jr., F.E.1
Califf, R.M.2
Pryor, D.B.3
Lee, K.L.4
Rosati, R.A.5
-
23
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 1995;57:289-300
-
(1995)
J R Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
24
-
-
25144494760
-
Prediction error estimation: A comparison of resampling methods
-
Molinaro AM, Simon R, Pfeiffer RM Prediction error estimation: a comparison of resampling methods Bioinformatics 2005; 21:3301-7.
-
(2005)
Bioinformatics
, vol.21
, pp. 3301-3307
-
-
Molinaro, A.M.1
Simon, R.2
Pfeiffer, R.M.3
-
25
-
-
34247392921
-
Prognosis of stage II colon cancer by non-neoplastic mucosa gene expression profiling
-
Barrier A, Roser F, Boelle PY, et al. Prognosis of stage II colon cancer by non-neoplastic mucosa gene expression profiling. Oncogene 2007; 26:2642-8
-
(2007)
Oncogene
, vol.26
, pp. 2642-2648
-
-
Barrier, A.1
Roser, F.2
Boelle, P.Y.3
-
26
-
-
33646681444
-
HER 2 and responsiveness of breast cancer to adjuvant chemotherapy
-
Pritchard Kl, Shepherd LE, O'Malley FP. et al. HER 2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med 2006; 354:2103-11
-
(2006)
N Engl J Med
, vol.354
, pp. 2103-2111
-
-
Pritchard, K.1
Shepherd, L.E.2
O'Malley, F.P.3
-
27
-
-
0032445262
-
Methodological challenges in the evaluation of prognostic factors in breast cancer
-
Altman DG, Lyman GH Methodological challenges in the evaluation of prognostic factors in breast cancer Breast Cancer Res Treat 1998;52:289-303
-
(1998)
Breast Cancer Res Treat
, vol.52
, pp. 289-303
-
-
Altman, D.G.1
Lyman, G.H.2
-
28
-
-
58849099873
-
-
Levine MN, Bramwell V, Pritchard K, et al. A pilot study of intensive cyclophosphamide, epirubicin and fluorouracil in patients with axillary node positive or locally advanced breast cancer Eur J Cancer 1992; 29A37-43.
-
Levine MN, Bramwell V, Pritchard K, et al. A pilot study of intensive cyclophosphamide, epirubicin and fluorouracil in patients with axillary node positive or locally advanced breast cancer Eur J Cancer 1992; 29A37-43.
-
-
-
-
29
-
-
21144435932
-
Adjuvant docetaxel for node-positive breast cancer
-
Martin M. Pienkowski T, Mackey J. et al. Adjuvant docetaxel for node-positive breast cancer N Engl J Med 2005; 352:2302-13.
-
(2005)
N Engl J Med
, vol.352
, pp. 2302-2313
-
-
Martin, M.1
Pienkowski, T.2
Mackey, J.3
-
30
-
-
33846231288
-
Schmid P. Dose dense chemotherapy for primary breast cancer
-
Kummel S, Rezai M, Kimmig R. Schmid P. Dose dense chemotherapy for primary breast cancer. Curr Opin Obstet Gynecol 2007; 19:75-81
-
(2007)
Curr Opin Obstet Gynecol
, vol.19
, pp. 75-81
-
-
Kummel, S.1
Rezai, M.2
Kimmig, R.3
-
31
-
-
0041779528
-
-
Paz MF, Wei S. Cigudosa JC, et al Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases Hum Mol Genet 2003; 12:2209-19
-
Paz MF, Wei S. Cigudosa JC, et al Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases Hum Mol Genet 2003; 12:2209-19
-
-
-
-
32
-
-
30044445818
-
Survey of differentially methylated promoters in prostate cancer cell lines
-
WangY, Yu Q, Cho AH, et al. Survey of differentially methylated promoters in prostate cancer cell lines. Neoplasia 2005; 7:748-60.
-
(2005)
Neoplasia
, vol.7
, pp. 748-760
-
-
Wang, Y.1
Yu, Q.2
Cho, A.H.3
-
33
-
-
33748055105
-
-
RauchT, Li H. Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-contaning genes in lung cancer cells Cancer Res 2006;66 7939-47
-
RauchT, Li H. Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-contaning genes in lung cancer cells Cancer Res 2006;66 7939-47
-
-
-
-
34
-
-
0035866809
-
Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation
-
Evron E, Umbricht CB, Korz D, et al. Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation. Cancer Res 2001; 61:2782-7.
-
(2001)
Cancer Res
, vol.61
, pp. 2782-2787
-
-
Evron, E.1
Umbricht, C.B.2
Korz, D.3
-
35
-
-
28544442448
-
Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy
-
Rosenbaum E, Hoque MO, Cohen Y, et al. Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy. Clin Cancer Res 2005; 11:8321-5.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8321-8325
-
-
Rosenbaum, E.1
Hoque, M.O.2
Cohen, Y.3
-
36
-
-
33846675127
-
Promoter methylation status of the cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer
-
Sakuma M, Akahira J, Ito K, et al. Promoter methylation status of the cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer. Cancer Sci 2007; 98:380-6.
-
(2007)
Cancer Sci
, vol.98
, pp. 380-386
-
-
Sakuma, M.1
Akahira, J.2
Ito, K.3
-
37
-
-
0037368187
-
Increased expression of BRCA1 mRNA predicts favorable response to anthracycline-containing chemotherapy in breast cancers
-
Egawa C, Motomura K, Miyoshi Y, et al. Increased expression of BRCA1 mRNA predicts favorable response to anthracycline-containing chemotherapy in breast cancers. Breast Cancer Res Treat 2003; 78:45-50.
-
(2003)
Breast Cancer Res Treat
, vol.78
, pp. 45-50
-
-
Egawa, C.1
Motomura, K.2
Miyoshi, Y.3
-
38
-
-
0037116616
-
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients
-
Look MP, van Putten WLJ, Duffy MJ, et al. Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J Natl Cancer Inst 2002; 94:116-28.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 116-128
-
-
Look, M.P.1
van Putten, W.L.J.2
Duffy, M.J.3
-
39
-
-
0036830198
-
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion
-
Guo Y, Pakneshan P, Gladu J, Slack A, Szyf M, Rabbani SA. Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. J Biol Chem 2002; 277:41571-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 41571-41579
-
-
Guo, Y.1
Pakneshan, P.2
Gladu, J.3
Slack, A.4
Szyf, M.5
Rabbani, S.A.6
-
40
-
-
27144437605
-
Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: Prognostic and therapeutic implications
-
Pakneshan P, Szyf M, Rabbani SA. Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: prognostic and therapeutic implications. Curr Cancer Drug Targets 2005; 5:471-88.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 471-488
-
-
Pakneshan, P.1
Szyf, M.2
Rabbani, S.A.3
-
41
-
-
2442602305
-
Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma
-
Pakneshan P,Tetu B, Rabbani SA. Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma. Clin Cancer Res 2004; 10: 3035-41.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3035-3041
-
-
Pakneshan, P.1
Tetu, B.2
Rabbani, S.A.3
-
42
-
-
0037102368
-
Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase- type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424)
-
Harbeck N, Kates RE, Look MP, et al. Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase- type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424). Cancer Res 2002; 62:4617-22.
-
(2002)
Cancer Res
, vol.62
, pp. 4617-4622
-
-
Harbeck, N.1
Kates, R.E.2
Look, M.P.3
-
43
-
-
34250221096
-
Characterization of the FAM110 gene family
-
Hauge H, Patzke S, Aasheim HC. Characterization of the FAM110 gene family. Genomics 2007; 90:14-27.
-
(2007)
Genomics
, vol.90
, pp. 14-27
-
-
Hauge, H.1
Patzke, S.2
Aasheim, H.C.3
-
44
-
-
33846545851
-
Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): A randomised controlled trial
-
Coombes RC, Kilburn LS, Snowdon CF, et al. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial. Lancet 2007; 369:559-70.
-
(2007)
Lancet
, vol.369
, pp. 559-570
-
-
Coombes, R.C.1
Kilburn, L.S.2
Snowdon, C.F.3
-
45
-
-
11444251764
-
Results of the ATAC (arimidex, tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for breast cancer
-
Howell A, Cuzick J, Baum M, et al. Results of the ATAC (arimidex, tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005; 365:60-2.
-
(2005)
Lancet
, vol.365
, pp. 60-62
-
-
Howell, A.1
Cuzick, J.2
Baum, M.3
|