IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells

Oncogene

Volumn 33, Issue 5, 2014, Pages 578-588

  Azar, W J ^a,b   Zivkovic, S ^a   Werther, G A ^a,b   Russo, V C ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

angiogenesis and CAM assay; cancer cells; IGFBP 2; Importin ; NLS; VEGF

Indexed keywords

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; AMINO ACID SEQUENCE; BETA KARYOPHERINS; CELL LINE, TUMOR; DNA; DNA-BINDING PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; MCF-7 CELLS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEAR LOCALIZATION SIGNALS; PROMOTER REGIONS, GENETIC; SEQUENCE ALIGNMENT; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84895072247     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.630     Document Type: Article

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