Non-covalent assembly of meso-tetra-4-pyridyl porphine with single-stranded DNA to form nano-sized complexes with hydrophobicity-dependent DNA release and anti-tumor activity

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 2, 2014, Pages 451-461

  Ghosh, Supratim ^a   Ucer, Kamil B ^b   D'Agostino, Ralph ^a   Grant, Ken ^a   Sirintrapun, Joseph ^a   Thomas, Michael J ^a   Hantgan, Roy ^a   Bharadwaj, Manish ^a   Gmeiner, William H ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

Author keywords

Cancer therapy; Multi modality nanoparticle; Photodynamic therapy; Porphyrin: DNA assembly

Indexed keywords

CANCER THERAPY; MULTI-MODALITY NANOPARTICLE; PHOTODYNAMIC THERAPY; PORPHYRIN: DNA ASSEMBLY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE; DNA, SINGLE-STRANDED; ENDOSOMES; FEMALE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID PEROXIDATION; MICE; MICE, NUDE; NANOMEDICINE; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHOTOSENSITIZING AGENTS; PORPHYRINS; REACTIVE OXYGEN SPECIES; STEARIC ACIDS; URINARY BLADDER NEOPLASMS;

EID: 84895071771     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.07.019     Document Type: Article

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