Starch biosynthesis, its regulation and biotechnological approaches to improve crop yields

Biotechnology Advances

Volumn 32, Issue 1, 2014, Pages 87-106

  Bahaji, Abdellatif ^a   Li, Jun ^a   Sánchez López, Ángela María ^a   Baroja Fernández, Edurne ^a   Muñoz, Francisco José ^a   Ovecka, Miroslav ^a,b   Almagro, Goizeder ^a   Montero, Manuel ^a   Ezquer, Ignacio ^a   Etxeberria, Ed ^c   Pozueta Romero, Javier ^a  

^a INSTITUTO DE AGROBIOTECNOLOGÍA   (Spain)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

ADPglucose; Calvin Benson cycle; Carbohydrate metabolism; Endocytosis; Genetic engineering; Microbial volatiles; MIVOISAP; Plant microbe interaction; Starch futile cycling; Sucrose synthase

Indexed keywords

STARCH; SUCROSE SYNTHASE;

ADPGLUCOSE; BIOSYNTHESIS; BIOTECHNOLOGY; CALVIN-BENSON CYCLE; CARBOHYDRATE METABOLISM; CROP; ENDOCYTOSIS; GENETIC ENGINEERING; METABOLISM; MICROBIAL VOLATILES; MIVOISAP; PHYSIOLOGY; PLANT-MICROBE INTERACTION; REVIEW; STARCH FUTILE CYCLING;

ADPGLUCOSE; CALVIN-BENSON CYCLE; CARBOHYDRATE METABOLISM; ENDOCYTOSIS; GENETIC ENGINEERING; MICROBIAL VOLATILES; MIVOISAP; PLANT-MICROBE INTERACTION; STARCH FUTILE CYCLING; SUCROSE SYNTHASE;

BIOTECHNOLOGY; CROPS, AGRICULTURAL; METABOLIC NETWORKS AND PATHWAYS; STARCH;

EID: 84895070549     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2013.06.006     Document Type: Review

References (252)

1. 14C]glucose. Plant Physiol 2005, 138:2220-2232.
2. Aoki N., Hirose T., Takahasi S., Ono K., Ishimaru K., Ohsugi R. Molecular cloning and expression analysis of a gene for a sucrose transporter in maize (Zea mays L.). Plant Cell Physiol 1999, 40:1072-1078.
3. Aoki N., Whitfeld P., Hoeren F., Scofield G., Newell K., Patrick J., et al. The sucrose transporter genes are expressed in the developing grain of hexaploid wheat. Plant Mol Biol 2002, 50:453-462.
4. Aoki N., Hirose T., Scofield G.N., Whitfeld P.R., Furbank R.T. The sucrose transporter gene family in rice. Plant Cell Physiol 2003, 44:223-232.
5. Asano T., Kunieda N., Omura Y., Ibe H., Kawasaki T., Takano M., et al. Rice SPK, a calmodulin-like domain protein kinase, is required for storage product accumulation during seed development: phosphorylation of sucrose synthase is a possible factor. Plant Cell 2002, 14:619-628.
6. Asatsuma S., Sawada C., Itoh K., Okito M., Kitajima A., Mitsui T. Involvement of α-amylase I-1 in starch degradation in rice chloroplasts. Plant Cell Physiol 2005, 46:858-869.
7. Backhausen J.E., Jöstingmeyer P., Scheibe R. Competitive inhibition of spinach leaf phosphoglucose isomerase isoenzymes by erythrose 4-phosphate. Plant Sci 1997, 130:121-131.
8. Baena-González E., Sheen J. Convergent energy and stress signalling. Trends Plant Sci 2008, 13:474-482.
9. Baena-González E., Rolland F., Thevelein J.M., Sheen J. A central integrator of transcription networks in plant stress and energy signalling. Nature 2007, 448:938-943.
10. Bahaji A., Li J., Ovecka M., Ezquer I., Muñoz F.J., Baroja-Fernández E., et al. Arabidopsis thaliana mutants lacking ADP-glucose pyrphosphorylase accumulate starch and wild-type ADP-glucose content: further evidence for the occurrence of important sources, other than ADP-glucose pyrophosphorylase, of ADP-glucose linked to leaf starch biosynthesis. Plant Cell Physiol 2011, 52:1162-1176.
11. Bahaji A., Muñoz F.J., Ovecka M., Baroja-Fernández E., Montero M., Li J., et al. Specific delivery of AtBT1 to mitochondria complements the aberrant growth and sterility phenotype of homozygous Atbt1 Arabidopsis mutants. Plant J 2011, 68:1115-1121.
12. Bahaji A., Ovecka M., Bárány I., Risueño M.C., Muñoz F.J., Baroja-Fernández E., et al. Dual targeting to mitochondria and plastids of AtBT1 and ZmBT1, two members of the mitochondrial carrier family. Plant Cell Physiol 2011, 52:597-609.
13. Ballicora M.A., Frueauf J.B., Fu Y., Schürmann P., Press J. Activation of the potato tuber ADP-glucose pyrophosphorylase by thioredoxin. J Biol Chem 2000, 275:1315-1320.
14. Baroja-Fernández E., Muñoz F.J., Saikusa T., Rodríguez-López M., Akazawa T., Pozueta-Romero J. Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. Plant Cell Physiol 2003, 44:500-509.
15. Baroja-Fernández E., Muñoz F.J., Zandueta-Criado A., Morán-Zorzano M.T., Viale A.M., Alonso-Casajús N., et al. Most of ADPglucose linked to starch biosynthesis occurs outside the chloroplast in source leaves. Proc Natl Acad Sci U S A 2004, 101:13080-13085.
16. Baroja-Fernández E., Muñoz F.J., Pozueta-Romero J. A response to Neuhaus et al. Trends Plant Sci 2005, 10:156-159.
17. Baroja-Fernández E., Etxeberria E., Muñoz F.J., Morán-Zorzano M.T., Alonso-Casajús N., González P., et al. An important pool of sucrose linked to starch biosynthesis is taken up by endocytosis in heterotrophic cells. Plant Cell Physiol 2006, 47:447-456.
18. Baroja-Fernández E., Muñoz F.J., Montero M., Etxeberria E., Sesma M.T., Ovecka M., et al. Enhancing sucrose synthase activity in transgenic potato (Solanum tuberosum L.) tubers results in increased levels of starch, ADPglucose and UDPglucose and total yield. Plant Cell Physiol 2009, 50:1651-1662.
19. Baroja-Fernández E., Muñoz F.J., Li J., Bahaji A., Almagro G., Montero M., et al. Sucrose synthase activity in the sus1/sus2/sus3/sus4 Arabidopsis mutant is sufficient to support normal cellulose and starch production. Proc Natl Acad Sci U S A 2012, 109:321-326.
20. Baroja-Fernández E., Bahaji A., Muñoz F.J., Li J., Sánchez-López A.M., Pujol P., et al. HPLC:MS analyses of ADPglucose content in mutants lacking plastidial phosphoglucose isomerase and ADPglucose pyrophosphorylase confirm the occurrence of various important sources of ADPglucose. Arabidopsis. XIII Congresso Luso-Espanhol de Fisiologia Vegetal. Lisbon, Portugal; 24-28 July 2013 2013.
21. Beckles D.M., Smith A.M., ap Rees T. A cytosolic ADP-glucose pyrophosphorylase is a feature of graminaceous endosperms. Plant Physiol 2001, 125:818-827.
22. Bollen M., Keppens S., Stalmans W. Specific features of glycogen metabolism in the liver. Biochem J 1998, 336:19-31.
23. Bowsher C.G., Lacey A.E., Hanke G.T., Clarkson D.T., Saker L.R., Stulen I., et al. The effect of Glc6P uptake and its subsequent oxidation within pea root plastids on nitrite reduction and glutamate synthesis. J Exp Bot 2007, 58:1109-1118.
24. Boyer C.D. Synthesis and breakdown of starch. Biochemical basis of plant breeding 1985, vol. 1:133-153. CRC Press Inc., Boca Raton. C.A. Neyra (Ed.).
25. Burrell M.M. Starch: the need for improved quality and quantity - an overview. J Exp Bot 2003, 54:451-456.
26. Caspar T., Huber S.C., Somerville C. Alterations in growth, photosynthesis, and respiration in a starchless mutant of Arabidopsis thaliana (L.) deficient in chloroplast phosphoglucomutase activity. Plant Physiol 1985, 79:11-17.
27. Chen J., Zhang J., Liu H., Hu Y., Huang Y. Molecular strategies in manipulation of the starch synthesis pathway for improving storage starch content in plants (review and prospect for increasing storage starch synthesis). Plant Physiol Biochem 2012, 61:1-8.
28. Cho M.-H., Lim H., Shin D.H., Jeon J.-S., Bhoo S.H., Park Y.-I., et al. Role of plastidic glucose translocator in the export of starch degradation products from the chloroplasts in Arabidopsis thaliana. New Phytol 2011, 190:101-112.
29. Chourey P.S., Nelson O.E. The enzymatic deficiency conditioned by the shrunken-1 mutations in maize. Biochem Genet 1976, 14:1041-1055.
30. Ciereszko I., Klezkowski L.A. Glucose and mannose regulate the expression of a major sucrose synthase gene in Arabidopsis via hexokinase-dependent mechanisms. Plant Physiol Biochem 2002, 40:907-911.
31. Crevillén P., Ballicora M.A., Mérida A., Preiss J., Romero J.M. The different large subunit isoforms of Arabidopsis thaliana ADP-glucose pyrophosphorylase confer distinct kinetic and regulatory properties to the heterotetrameric enzyme. J Biol Chem 2003, 278:28508-28515.
32. Crevillén P., Ventriglia T., Pinto F., Orea A., Mérida A., Romero J.M. Differential pattern of expression and sugar regulation of Arabidopsis thaliana ADP-glucose pyrophosphorylase-encoding genes. J Biol Chem 2005, 280:8143-8149.
33. Cumino A.C., Marcozzi C., Barreiro R., Salerno G.L. Carbon cycling in Anabaena sp. PCC7120. Sucrose synthesis in the heterocysts and possible role in nitrogen fixation. Plant Physiol 2007, 143:1385-1397.
34. Curatti L., Porchia A.C., Herrera-Estrella L., Salerno G.L. A prokaryotic sucrose synthase gene (susA) isolated from a filamentous nitrogen-fixing cyanobacterium encodes a protein similar to those of plants. Planta 2000, 211:729-735.
35. D'Hulst C., Mérida A. The priming of storage glucan synthesis from bacteria to plants: current knowledge and new developments. New Phytol 2010, 188:13-21.
36. Dankert M., Goncalves I.R.J., Recondo E. Adenosine diphosphate glucose:orthophosphate adenylyltransferase in wheat germ. Biochim Biophys Acta 1964, 81:78-85.
37. David M., Petit W.A., Laughlin M.R., Shulman R.G., King J.E., Barrett E.J. Simultaneous synthesis and degradation of rat liver glycogen. J Clin Invest 1990, 86:612-617.
38. Davies H.V., Shepherd L.V.T., Burrell M.M., Carrari F., Urbanczyk-Wochniak E., Leisse A., et al. Modulation of fructokinase activity of potato (Solanum tuberosum) results in substantial shifts in tuber metabolism. Plant Cell Physiol 2005, 46:1103-1115.
39. Debast S., Nunes-Nesi A., Hajirezaei M.R., Hofmann J., Sonnewald U., Fernie A.R., et al. Altering trehalose-6-phosphate content in transgenic potato tubers affects tuber growth and alters responsiveness to hormones during sprouting. Plant Physiol 2011, 156:1754-1771.
40. Déjardin A., Sokolov L.N., Kleczkowski L.A. Sugar/osmoticum levels modulate differential abscisic acid-independent expression of two stress-response sucrose synthase genes in Arabidopsis. Biochem J 1999, 344:503-509.
41. Delmer D.P. The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings. J Biol Chem 1972, 247:3822-3828.
42. Denyer K., Foster J., Smith A.M. The contributions of ADP-glucose pyrophosphorylase and starch-branching enzyme to the control of starch synthesis in developing pea embryos. Planta 1995, 197:57-62.
43. Denyer K., Dunlap F., ThornbjØrnsen T., Keeling P., Smith A.M. The major form of ADP-glucose pyrophosphorylase in maize (Zea mays L.) endosperm is extra-plastidial. Plant Physiol 1996, 112:779-785.
44. Dietz K.-J. A possible rate-limiting function of chloroplast hexosemonophosphate isomerase in starch synthesis of leaves. Biochim Biophys Acta 1985, 839:240-248.
45. Entwistle G., ap Rees T. Enzymic capacities of amyloplasts from wheat endosperm. Biochem J 1988, 255:391-396.
46. Etxeberria E., Baroja-Fernández E., Muñoz F.J., Pozueta-Romero J. Sucrose inducible endocytosis as a mechanism for nutrient uptake in heterotrophic plant cells. Plant Cell Physiol 2005, 46:474-481.
47. Etxeberria E., González P., Pozueta-Romero J. Sucrose transport in Citrus juice cells: evidence for an endocytic transport system. J Am Soc Hortic Sci 2005, 130:269-274.
48. Etxeberria E., Pozueta-Romero J., González P. In and out of the plant storage vacuole. Plant Sci 2012, 190:52-61.
49. Ezquer I., Li J., Ovecka M., Baroja-Fernández E., Muñoz F.J., Montero M., et al. Microbial volatile emissions promote accumulation of exceptionally high levels of starch in leaves in mono- and dicotyledonous plants. Plant Cell Physiol 2010, 51:1674-1693.
50. Ezquer I., Li J., Ovecka M., Baroja-Fernández E., Muñoz F.J., Montero M., et al. A suggested model for potato MIVOISAP involving functions of central carbohydrate and amino acid metabolism, as well as acting cytoskeleton and endocytosis. Plant Signal Behav 2010, 12:1638-1641.
51. Fernie A.R., Tauberger E., Lytovchenko A., Roessner U., Willmitzer L., Trethewey R.N. Antisense repression of cytosolic phosphoglucomutase in potato (Solanum tuberosum) results in severe growth retardation, reduction in tuber number and altered carbon metabolism. Planta 2002, 214:510-520.
52. Ferreira S.J., Senning M., Sonnewald S., Kebling P.-M., Goldstein R., Sonnewald U. Comparative transcriptome analysis coupled to X-ray CT reveals sucrose supply and growth velocity as major determinants of potato tuber starch biosynthesis. BMC Genomics 2010, 11:93.
53. Fettke J., Albrecht T., Hejazi M., Mahlow S., Nakamura Y., Steup M. Glucose 1-phosphate is efficiently taken up by potato (Solanum tuberosum) tuber parenchyma cells and converted to reserve starch granules. New Phytol 2010, 185:663-675.
54. Fettke J., Malinova I., Albrecht T., Hejazi M., Steup M. Glucose-1-phosphate transport into protoplasts and chloroplasts from leaves of Arabidopsis. Plant Physiol 2011, 155:1723-1734.
55. Figueroa C.M., Diez M.D.A., Kuhn M.L., McEwen S., Salerno G.L., Iglesias A.A., et al. The unique nucleotide specificity of the sucrose synthase from Thermosynechococcus elongatus. FEBS Lett 2013, 587:165-169.
56. Fox T.C., Geiger D.R. Effects of decreased net carbon exchange on carbohydrate metabolism in sugar beet source leaves. Plant Physiol 1984, 76:763-768.
57. Frehner M., Pozueta-Romero J., Akazawa T. Enzyme sets of glycolysis, gluconeogenesis, and oxidative pentose phosphate pathway are not complete in nongreen highly purified amyloplasts of sycamore (Acer pseudoplatanus L.) cells suspension cultures. Plant Physiol 1990, 94:538-544.
58. Fu H., Park W.D. Sink- and vascular-associated sucrose synthase functions are encoded by different gene classes in potato. Plant Cell 1995, 7:1369-1385.
59. Fu F.-F., Xue H.-W. Coexpression analysis identifies rice starch regulator1, a rice AP2/EREBP family transcription factor, as a novel rice starch biosynthesis regulator. Plant Physiol 2010, 154:927-938.
60. Fu H., Kim S.Y., Park W.D. A potato Sus3 sucrose synthase gene contains a context-dependent 3' element and a leader intron with both positive and negative tissue-specific effects. Plant Cell 1995, 7:1395-1403.
61. Fu Y., Ballicora M.A., Leykam J.F., Preiss J. Mechanism of reductive activation of potato tuber ADP-glucose pyrophosphorylase. J Biol Chem 1998, 273:25045-25052.
62. Fulton D.C., Stettler M., Mettler T., Vaughan C.K., Li J., Francisco P., et al. β-Amylase4, a noncatalytic protein required for starch breakdown, acts upstream of three active β-amylases in Arabidopsis chloroplasts. Plant Cell 2008, 20:1040-1058.
63. Gámez-Arjona F.M., Li J., Raynaud S., Baroja-Fernández E., Muñoz F.J., Ovecka M., et al. Enhancing the expression of starch synthase class IV results in increased levels of both transitory and long-term storage starch. Plant Biotechnol J 2011, 9:1049-1060.
64. 13C-NMR investigation. Eur J Biochem 1992, 207:155-162.
65. Geigenberger P., Stamme C., Tjaden J., Schulz A., Quick P.W., Betsche T., et al. Tuber physiology and properties of starch from tubers of transgenic potato plants with altered plastidic adenylate transporter activity. Plant Physiol 2001, 125:1667-1678.
66. Geigenberger P., Kolbe A., Tiessen A. Redox regulation of carbon storage and partitioning in response to light and sugars. J Exp Bot 2005, 56:1469-1479.
67. George G.M., van der Merwe M.J., Nunes-Nesi A., Bauer R., Fernie A.R., Kossmann J., et al. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. Plant Physiol 2010, 154:55-66.
68. Gerrits N., Turk S.C.H.J., van Dun K.P.M., Hulleman S.H.D., Visser R.G.F., Weisbeek P.J., et al. Sucrose metabolism in plastids. Plant Physiol 2001, 125:926-934.
69. Gibbs M., Kandler O. Asymmetric distribution of C14 in sugars formed during photosynthesis. Proc Natl Acad Sci U S A 1957, 43:446-451.
70. Gibon Y., Bläsing O.E., Palacios-Rojas N., Pankovic D., Hendriks J.H.M., Fishan J., et al. Adjustment of diurnal starch turnover to short days: depletion of sugar during the night leads to a temporary inhibition of carbohydrate utilization, accumulation of sugars and post-translational activation of ADP-glucose pyrophosphorylase in the following light period. Plant J 2004, 39:847-862.
71. Giese J.-O., Herbers K., Hoffmann M., Klösgen R.B., Sonnewald U. Isolation and functional characterization of a novel plastidic hexokinase from Nicotiana tabacum. FEBS Lett 2005, 579:827-831.
72. Giroux M.J., Boyer C., Feix G., Hannah L.C. Coordinated transcriptional regulation of storage genes in the maize endosperm. Plant Physiol 1994, 106:713-722.
73. Giroux M.J., Shaw J., Barry G., Cobb B.G., Greene T., Okita T., et al. A single gene mutation that increases maize seed weight. Proc Natl Acad Sci U S A 1996, 93:5824-5829.
74. Glaring M.A., Skryhan K., Kötting O., Zeeman S.C., Blennow A. Comprehensive survey of redox sensitive starch metabolizing enzymes in Arabidopsis thaliana. Plant Physiol Biochem 2012, 58:89-97.
75. Goldemberg J. Ethanol for a sustainable energy future. Science 2007, 315:808-810.
76. Gómez-Casati D.F., Iglesias A.A. ADP-glucose pyrophosphorylase from wheat endosperm. Purification and characterization of an enzyme with novel regulatory properties. Planta 2002, 214:428-434.
77. Guedon E., Desvaux M., Petitdemange H. Kinetic analysis of Clostridium cellulolyticum carbohydrate metabolism: importance of glucose 1-phosphate and glucose 6-phosphate branch points for distribution of carbon fluxes inside and outside cells as revealed by steady-state continuous culture. J Bacteriol 2000, 183:2010-2017.
78. Hädrich N., Hendriks J.H.M., Kötting O., Arrivault S., Feil R., Zeeman S.C., et al. Mutagenesis of cysteine 81 prevents dimerization of the APS1 subunit of ADP-glucose pyrophosphorylase and alters diurnal starch turnover in Arabidopsis thaliana leaves. Plant J 2012, 70:231-242.
79. Haferkamp I. The diverse members of the mitochondrial carrier family in plants. FEBS Lett 2007, 581:2375-2379.
80. Hakata M., Kuroda M., Miyashita T., Yamaguchi T., Kojima M., Sakakibara H., et al. Suppression of α-amylase genes improves quality of rice grain ripened under high temperature. Plant Biotechnol J 2012, 10:1110-1117.
81. Hardin S.C., Winter H., Huber S.C. Phosphorylation of the amino terminus of maize sucrose synthase in relation to membrane association and enzyme activity. Plant Physiol 2004, 134:1427-1438.
82. Harrington G.N., Nussbaumer Y., Wang X.-D., Tegeder M., Franceschi V.R., Frommer W.B., et al. Spatial and temporal expression of sucrose transport-related genes in developing cotyledons of Vicia faba L. Protoplasma 1997, 200:35-50.
83. Harrison C.J., Hedley C.L., Wang T.L. Evidence that the rug3 locus of pea (Pisum sativum L.) encodes plastidial phosphoglucomutase confirms that the imported substrate for starch synthesis in pea amyloplasts is glucose-6-phosphate. Plant J 1998, 13:753-762.
84. Hatzfeld W.-D., Stitt M. A study of the rate of recycling of triose phosphates in heterotrophic Chenopodium rubrum cells, potato tubers, and maize endosperm. Planta 1990, 180:198-204.
85. Havir E.A., Gibbs M. Studies of the reductive pentose phosphate cycle in intact and reconstituted chloroplast systems. J Biol Chem 1963, 238:3183-3187.
86. Hendriks J.H.M., Kolbe A., Gibon Y., Stitt M., Geigenberger P. ADP-glucose pyrophosphorylase is activated by posttranslational redox-modification in response to light and to sugars in leaves of Arabidopsis and other plant species. Plant Physiol 2003, 133:838-849.
87. Hennen-Bierwagen T.A., Liu F., Marsh R.S., Kim S., Gan Q., Tetlow I.J., et al. Starch biosynthetic enzymes from developing maize endosperm associate in multisubunit complexes. Plant Physiol 2008, 146:1892-1908.
88. Heuer B., Hansen M.J., Anderson L.E. Light modulation of phosphofructokinase in pea leaf chloroplasts. Plant Physiol 1982, 69:1404-1406.
89. Hill S.T., ap Rees T. Fluxes of carbohydrate metabolism in ripening bananas. Planta 1994, 192:52-60.
90. Hirose T., Imaizumi N., Scofield G.N., Furbank R.T., Ohsugi R. cDNA cloning and tissue specific expression of a gene for sucrose transporter from rice (Oryza sativa L.). Plant Cell Physiol 1997, 38:1389-1396.
91. Hylton C., Smith A.M. The rb mutation causes structural and regulatory changes in ADPglucose pyrophosphorylase from developing embryos. Plant Physiol 1992, 99:1626-1634.
92. Ihemere U., Arias-Garzon D., Lawrence S., Sayre R. Genetic modification of cassava for enhanced starch production. Plant Biotechnol J 2006, 4:453-465.
93. Johnson P.E., Patron N.J., Bottrill A.R., Dinges J.R., Fahy B.F., Parker M.L., et al. A low-starch barley mutant, Riso 16, lacking the cytosolic small subunit of ADP-glucose pyrophosphorylase, reveals the importance of the cytosolic isoform and the identity of the plastidial small subunit. Plant Physiol 2003, 131:684-696.
94. Jones T.W.A., Gottlieb L.D., Pichersky E. Reduced enzyme activity and starch level in an induced mutant of chloroplast phosphoglucose isomerase. Plant Physiol 1986, 81:367-371.
95. Kammerer B., Fischer K., Hilpert B., Schubert S., Gutensohn M., Weber A., et al. Molecular characterization of a carbon transporter in plastids from heterotrophic tissues: the glucose 6-phosphate/phosphate antiporter. Plant Cell 1998, 10:105-117.
96. Kandler O., Gibbs M. Asymmetric distribution of C14 in the glucose phosphates formed during photosynthesis. Plant Physiol 1956, 31:411-412.
97. Kang F., Rawsthorne S. Metabolism of glucose-6-phosphate and utilization of multiple metabolites for fatty acid synthesis by plastids from developing oilseed rape embryos. Planta 1996, 199:321-327.
98. Kaplan F., Guy C.L. RNA interference of Arabidopsis beta-amylase8 prevents maltose accumulation upon cold shock and increases sensitivity of PSII photochemical efficiency to freezing stress. Plant J 2005, 44:730-743.
99. Keeling P.L., Wood J.R., Tyson R.H., Bridges I.G. Starch biosynthesis in developing wheat grain: evidence against the direct involvement of triose phosphates in the metabolic pathway. Plant Physiol 1988, 87:311-319.
100. Keeling P.L., Bacon P.J., Holt D.C. Elevated temperature reduces starch deposition in wheat endosperm by reducing the activity of soluble starch synthase. Planta 1993, 191:342-348.
101. Kelly G.J., Latzko E. Oat leaf phosphoglucose isomerase: competitive inhibition by erythrose-4-phosphate. Photosynth Res 1980, 1:181-187.
102. Kirchberger S., Leroch M., Huynen M.A., Wahl M., Neuhaus H.E., Tjaden J. Molecular and biochemical analysis of the plastidic ADP-glucose transporter (ZmBT1) from Zea mays. J Biol Chem 2007, 282:22481-22491.
103. Kirchberger S., Tjaden J., Neuhaus H.E. Characterization of the Arabidopsis Brittle 1 transport protein and impact of reduced activity on plant metabolism. Plant J 2008, 56:51-63.
104. Kitajima A., Asatsuma S., Okada H., Hamada Y., Kaneko K., Nanjo Y., et al. The rice α-amylase glycoprotein is targeted from the Golgi apparatus through the secretory pathway to the plastids. Plant Cell 2009, 21:2844-2858.
105. Kleczkowski L.A. Back to the drawing board: redefining starch synthesis in cereals. Trends Plant Sci 1996, 1:363-364.
106. Kleczkowski L.A. A phosphoglycerate to inorganic phosphate ratio is the major factor in controlling starch levels in chloroplasts via ADP-glucose pyrophosphorylase regulation. FEBS Lett 1999, 448:153-156.
107. Kleczkowski L.A., Villand P., Lüthi E., Olsen O.-A., Preiss J. Insensitivity of barley endosperm ADP-glucose pyrophosphorylase to 3-phosphoglycerate and orthophosphate regulation. Plant Physiol 1993, 101:179-186.
108. Kleczkowski L.A., Kunz S., Wilczynska M. Mechanisms of UDP-glucose synthesis in plants. Crit Rev Plant Sci 2010, 29:191-203.
109. Koch K.E., Nolte K.D., Duke E.R., McCarty D.R., Avigne W.T. Sugar levels modulate differential expression of maize sucrose synthase genes. Plant Cell 1992, 4:59-69.
110. Kofler H., Häusler R.E., Schulz B., Gröner F., Flügge U.-I., Weber A. Molecular characterization of a new mutant allele of the plastid phosphoglucomutase in Arabidopsis, and complementation of the mutant with the wild-type cDNA. Mol Gen Genet 2000, 262:978-986.
111. Kolbe A., Tiessen A., Schluepmann H., Paul M., Ulrich S., Geigenberger P. Trehalose 6-phosphate regulates starch synthesis via posttranslational redox activation of ADP-glucose pyrophosphorylase. Proc Natl Acad Sci U S A 2005, 102:11118-11123.
112. Kruckeberg L., Neuhaus H.E., Feil R., Gottlieb L.D., Stitt M. Decreased-activity mutants of phosphoglucose isomerase in the cytosol and chloroplast of Clarkia xantiana. Biochem J 1989, 261:457-467.
113. Kühn C., Hajirezaei M.-R., Fernie A.R., Roessner-Tunali U., Czechowski T., Hirner B., et al. The sucrose transporter StSUT1 localizes to sieve elements in potato tuber phloem and influences tuber physiology and development. Plant Physiol 2003, 131:102-113.
114. Kunz H.H., Häusler R.E., Fettke J., Herbst K., Niewiadomski P., Gierth M., et al. The role of plastidial glucose-6-phosphate/phosphate translocators in vegetative tissues of Arabidopsis thaliana mutants impaired in starch biosynthesis. Plant Biol (Stuttg) 2010, 12(Suppl. 1):115-128.
115. Laurie S., McKibbin R.S., Halford N.G. Antisense SNF1-related (SnRK1) protein kinase gene represses transient activity of an α-amylase (α-Amy2) gene promoter in cultured wheat embryos. J Exp Bot 2003, 54:739-747.
116. Lefebvre S., Lawson T., Fryer M., Zakhleniuk O.V., Lloyd J.C., Raines C.A. Increased sedoheptulose-1,7-bisphosphatase activity in transgenic tobacco plants stimulates photosynthesis and growth from an early stage in development. Plant Physiol 2005, 138:451-460.
117. Leggewie G., Kolbe A., Lemoine R., Roessner U., Lytovchenko A., Zuther E., et al. Overexpression of the sucrose transporter SoSUT1 in potato results in alterations in leaf carbon partitioning and in tuber metabolism but has little impact on tuber morphology. Planta 2003, 217:158-167.
118. Li J., Ezquer I., Bahaji A., Ovecka M., Baroja-Fernández E., Muñoz F.J., et al. Microbial volatiles induced accumulation of exceptionally high levels of starch in Arabidopsis leaves is a process involving NTRC and starch synthases class III and IV. Mol Plant Microbe Interact 2011, 24:1165-1178.
119. Li N., Zhang S., Zhao Y., Li B., Zhang J. Over-expression of AGPase genes enhances seed weight and starch content in transgenic maize. Planta 2011, 233:241-250.
120. Li J., Almagro G., Muñoz F.J., Baroja-Fernández E., Bahaji A., Montero M., et al. Post-translational redox modification of ADP-glucose pyrophosphorylase in response to light is not a major determinant of fine regulation of transitory starch accumulation in Arabidopsis leaves. Plant Cell Physiol 2012, 53:433-444.
121. Li J., Baroja-Fernández E., Bahaji A., Muñoz F.J., Ovecka M., Montero M., et al. Enhancing sucrose synthase activity results in increased levels of starch and ADP-glucose in maize (Zea mays L.) seed endosperms. Plant Cell Physiol 2013, 54:282-294.
122. Lin T.-P., Caspar T., Somerville C.R., Preiss J. Isolation and characterization of a starchless mutant of Arabidopsis thaliana (L.) Heynh lacking ADPglucose pyrophosphorylase activity. Plant Physiol 1988, 86:1131-1135.
123. Liu T.-T.Y., Shannon J.C. Measurement of metabolites associated with nonaqueously isolated starch granules from immature Zea mays L. endosperm. Plant Physiol 1981, 67:525-529.
124. Liu K.-C., Boyer C.D., Shannon J.C. Carbohydrate transfer into isolated maize (Zea mays L.) amyloplasts (abstract no. 234). Plant Physiol 1992, 99:S-39.
125. Lozovaya V.V., Zabotina O.A., Widholm J.M. Synthesis and turnover of cell-wall polysaccharides and starch in photosynthetic soybean suspension cultures. Plant Physiol 1996, 111:921-929.
126. Lu C.-A., Lin C.-C., Lee K.-W., Chen J.-L., Huang L.-F., Ho S.-L., et al. The SnRK1 protein kinase plays a key role in sugar signaling during germination and seedling growth of rice. Plant Cell 2007, 19:2484-2499.
127. Lunn J., Feil R., Hendriks J.H.M., Gibon Y., Morcuende R., Osuna D., et al. Sugar-induced increases in trehalose 6-phosphate are correlated with redox activation of ADPglucose pyrophosphorylase and higher rates of starch synthesis in Arabidopsis thaliana. Biochem J 2006, 397:139-148.
128. Lytovchenko A., Bieberich K., Willmitzer L., Fernie A.R. Carbon assimilation and metabolism in potato leaves deficient in plastidial phosphoglucomutase. Planta 2002, 215:802-811.
129. Mangelsdorf P.C. The genetics and morphology of some endosperm characters in maize. Conn Agric Exp Stn Bull 1926, 279:509-614.
130. Martínez-Barajas E., Delatte T., Schluepmann H., de Jong G.J., Somsen G.W., Nunes C., et al. Wheat grain development is characterized by remarkable trehalose 6-phosphate accumulation pregrain filling: tissue distribution and relationship to SNF1-related protein kinase 1 activity. Plant Physiol 2011, 156:373-381.
131. Massillon D., Bollen M., De Wulf H., Overloop K., Vanstapel F., Van Hecke P., et al. Demonstration of a glycogen/glucose 1-phosphate cycle in hepatocytes from fasted rats. J Biol Chem 1995, 270:19351-19356.
132. McCoy J.G., Arabshahi A., Bitto E., Bingman C.A., Ruzicka F.J., Frey P.A., et al. Structure and mechanism of an ADP-glucose phosphorylase from Arabidopsis thaliana. Biochemistry 2006, 45:3145-3162.
133. McKibbin R.S., Muttucumaru N., Paul M.J., Powers S.J., Burrell M.M., Coates S., et al. Production of high-starch, low glucose potatoes through over-expression of the metabolic regulator SnRK1. Plant Biotechnol J 2006, 4:409-418.
134. McLennan A.G. The Nudix hydrolase superfamily. Cell Mol Life Sci 2006, 63:123-143.
135. Meyer F.D., Smidansky E.D., Beecher B.B., Greene T.W., Giroux M.J. The maize Sh2r6hs ADP-glucose pyrophosphorylase (AGP) large subunit confers enhanced AGP properties in transgenic wheat (Triticum aestivum). Plant Sci 2004, 167:899-911.
136. Michalska J., Zauber H., Buchanan B.B., Cejudo F.J., Geigenberger P. NTRC links built-in thioredoxin to light and sucrose in regulating starch synthesis in chloroplasts. Proc Natl Acad Sci U S A 2009, 106:9908-9913.
137. Mikkelsen R., Mutenda K.E., Mant A., Schürmann P., Blennow A. α-Glucan, water dikinase (GWD): a plastidic enzyme with redox-regulated and coordinated catalytic activity and binding affinity. Proc Natl Acad Sci U S A 2005, 102:1785-1790.
138. Millar A.H., Heazlewood J.L. Genomic and proteomic analysis of mitochondrial carrier proteins in Arabidopsis. Plant Physiol 2003, 131:443-453.
139. Miyagawa Y., Tamoi M., Shigeoka S. Overexpression of a cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase in tobacco enhance photosynthesis and growth. Nat Biotechnol 2001, 19:965-969.
140. Möhlmann T., Tjaden J., Henrichs G., Quick W.P., Häusler R., Neuhaus H.E. ADPglucose drives starch synthesis in isolated maize endosperm amyloplasts. Characterization of starch synthesis and transport properties across the amyloplast envelope. Biochem J 1997, 324:503-509.
141. Montero M., Eydallin G., Viale A.M., Almagro G., Muñoz F.J., Rahimpour M., et al. Escherichia coli glycogen metabolism is controlled by the PhoP-PhoQ regulatory system at submillimolar environmental Mg2+ concentrations, and is highly interconnected with a wide variety of cellular processes. Biochem J 2009, 424:129-141.
142. Montero M., Almagro G., Eydallin G., Viale A.M., Muñoz F.J., Bahaji A., et al. Escherichia coli glycogen genes are organized in a single glgBXCAP transcriptional unit possessing an alternative suboperonic promoter within glgC that directs glgAP expression. Biochem J 2011, 433:107-118.
143. Mooney B.P. The second green revolution? Production of plant-based biodegradable plastics. Biochem J 2009, 418:219-232.
144. Moreno-Bruna B., Baroja-Fernández E., Muñoz F.J., Bastarrica-Berasategui A., Zandueta-Criado A., Rodríguez-López M., et al. Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A 2001, 98:8128-8132.
145. Müller J., Mettbach U., Menzel D., Samaj J. Molecular dissection of endosomal compartments in plants. Plant Physiol 2007, 145:293-304.
146. Müller-Röber B.T., Sonnewald U., Willmitzer L. Inhibition of the ADP-glucose pyrophosphorylase in transgenic potatoes leads to sugar-storing tubers and influences tuber formation and expression of tuber storage protein genes. EMBO J 1992, 11:1229-1238.
147. Muñoz F.J., Baroja-Fernández E., Morán-Zorzano M.T., Viale A.M., Etxeberria E., Alonso-Casajús N., et al. Sucrose synthase controls both intracellular ADPglucose levels and transitory starch biosynthesis in source leaves. Plant Cell Physiol 2005, 46:1366-1376.
148. Muñoz F.J., Morán-Zorzano M.T., Alonso-Casajús N., Baroja-Fernández E., Etxeberria E., Pozueta-Romero J. New enzymes, new pathways and alternative view on starch biosynthesis in both photosynthetic and heterotrophic tissues of plants. Biocatal Biotransform 2006, 24:63-76.
149. Muñoz F.J., Baroja-Fernández E., Ovecka M., Li J., Mitsui T., Sesma M.T., et al. Plastidial localization of a potato "Nudix" hydrolase of ADPglucose linked to starch biosynthesis. Plant Cell Physiol 2008, 49:1734-1746.
150. Murata T. Partial purification and some properties of ADP-glucose phosphorylase from potato tubers. Agric Biol Chem 1977, 41:1995-2002.
151. Murayama S., Handa H. Genes for alkaline/neutral invertase in rice: alkaline/neutral invertases are located in plant mitochondria and also in plastids. Planta 2007, 225:1193-1203.
152. Naeem M., Tetlow I.J., Emes M.J. Starch synthesis in amyloplasts purified from developing tubers. Plant J 1997, 11:1095-1103.
153. Nagai Y.S., Sakulsingharoj C., Edwards G.E., Satoh H., Greene T.W., Blakeslee B., et al. Control of starch synthesis in cereals: metabolite analysis of transgenic rice expressing and up-regulated cytosplasmic ADP-glucose pyrophosphorylase in developing seeds. Plant Cell Physiol 2009, 50:635-643.
154. 11. Plant Cell Physiol 1998, 39:1337-1341.
155. Nanjo Y., Oka H., Ikarashi N., Kanedo K., Kitajima A., Mitsui T., et al. Rice plastidial N-glycosylated nucleotide pyrophosphatase/phosphodiesterase is transported from the ER-Golgi to the chloroplast through the secretory pathway. Plant Cell 2006, 18:2582-2592.
156. Neuhaus H.E., Henrichs G., Scheibe R. Starch degradation in intact amyloplasts isolated from cauliflower floral buds (Brassica oleracea L.). Planta 1995, 195:496-504.
157. Neuhaus H.E., Häusler R.E., Sonnewald U. No need to shift the paradigm on the metabolic pathway to transitory starch in leaves. Trends Plant Sci 2005, 10:154-156.
158. Niewiadomski P., Knappe S., Geimer S., Fischer K., Schulz B., Unte U.S., et al. The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development. Plant Cell 2005, 17:760-775.
159. Okazaki Y., Shimojima M., Sawada Y., Yoyooka K., Narisawa T., Mochida K., et al. A chloroplastic UDP-glucose pyrophosphorylase from Arabidopsis is the committed enzyme for the first step of sulfolipid biosynthesis. Plant Cell 2009, 21:892-909.
160. Olejnik K., Kraszewska E. Cloning and characterization of an Arabidopsis thaliana Nudix hydrolase homologous to the mammalian GFG protein. Biochim Biophys Acta 2005, 1752:133-141.
161. Olsson T., Thelander M., Ronne H. A novel type of chloroplast stromal hexokinase is the major glucose-phosphorylating enzyme in the moss Physcomitrella patens. J Biol Chem 2003, 278:44439-44447.
162. Overlach S., Diekmann W., Raschke K. Phosphate translocator of isolated guard-cell chloroplasts from Pisum sativum L. transports glucose 6-phosphate. Plant Physiol 1993, 101:1201-1207.
163. Patron N.J., Greber B., Fahy B.F., Laurie D.A., Parker M.L., Denyer K. The lys5 mutations of barley reveal the nature and importance of plastidial ADP-glc transporters for starch synthesis in cereal endosperm. Plant Physiol 2004, 135:2088-2097.
164. Periappuram C., Steinhaurer L., Barton D.L., Taylor D.C., Chatson B., Zou J. The plastidic phosphoglucomutase from Arabidopsis. A reversible enzyme reaction with an important role in metabolic control. Plant Physiol 2000, 122:1193-1199.
165. Pontis H.G., Babio J.R., Salerno G. Reversible unidirectional inhibition of sucrose synthase activity by disulfides. Proc Natl Acad Sci U S A 1981, 78:6667-6669.
166. Porchia A.C., Curatti L., Salerno G.L. Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence. Planta 1999, 210:34-40.
167. Pozueta-Romero J., Akazawa T. Biochemical mechanism of starch biosynthesis in amyloplasts from cultured cells of sycamore (Acer pseudoplatanus). J Exp Bot 1993, 44S:297-306.
168. Pozueta-Romero J., Ardila F., Akazawa T. ADP-glucose transport by the chloroplast adenylate translocator is linked to starch biosynthesis. Plant Physiol 1991, 97:1565-1572.
169. Pozueta-Romero J., Frehner M., Viale A., Akazawa T. Direct transport of ADPglucose by an adenylate translocator is linked to starch biosynthesis in amyloplasts. Proc Natl Acad Sci U S A 1991, 88:5769-5773.
170. Pulido P., Spínola M.C., Kirchsteiger K., Guinea M., Pascual M.B., Sahrawy M., et al. Functional analysis of the pathways for 2-Cys peroxiredoxin reduction in Arabidopsis thaliana chloroplasts. J Exp Bot 2010, 14:4043-4054.
171. Purcell P.C., Smith A.M., Halford N.G. Antisense expression of a sucrose non-fermenting-1-related protein kinase sequence in potato results in decreased expression of sucrose synthase in tubers and loss of sucrose-inducibility of sucrose synthase transcripts in leaves. Plant J 1998, 14:195-202.
172. Ragel P. Identificación y caracterización de los elementos implicados en el inicio de la síntesis de almidón en plantas 2012, [PhD. Thesis].
173. Rahimpour M., Montero M., Almagro G., Viale A.M., Sevilla A., Canovas M., et al. GlgS, previously described as a glycogen synthesis control protein, negatively regulates motility and biofilm formation in Escherichia coli. Biochem J 2013, 452:559-573.
174. Ral J.P., Bowerman A.F., Li Z., Sirault X., Furbank R., Pritchard J.R., et al. Down-regulation of glucan, water-dikinase activity in wheat endosperm increases vegetative biomass and yield. Plant Biotechnol J 2012, 10:871-882.
175. Regierer B., Fernie A.R., Springer F., Perez-Melis A., Leisse A., Koehl K., et al. Starch content and yield increase as a result of altering adenylate pools in transgenic plants. Nat Biotechnol 2002, 20:1256-1260.
176. Rodríguez-López M., Baroja-Fernández E., Zandueta-Criado A., Pozueta-Romero J. Adenosine diphosphate glucose pyrophosphatase: a plastidial phosphodiesterase that prevents starch biosynthesis. Proc Natl Acad Sci U S A 2000, 97:8705-8710.
177. Roldán I., Wattebled F., Mercedes Lucas M., Delvalle D., Planchot V., Jimenez S., et al. The phenotype of soluble starch synthase IV defective mutants of Arabidopsis thaliana suggests a novel function of elongation enzymes in the control of starch granule formation. Plant J 2007, 49:492-504.
178. Rolletschek H., Hijirezaei M.-R., Wobus U., Weber H. Antisense-inhibition of ADP-glucose pyrophosphorylase in Vicia narbonensis seeds increases soluble sugars and leads to higher water an nitrogen uptake. Planta 2002, 214:954-964.
179. Rolletschek H., Nguyen T.H., Häusler R.E., Rutten T., Göbel C., Feussner I., et al. Antisense inhibition of the plastidial glucose-6-phosphate/phosphate translocator in Vicia seeds shifts cellular differentiation and promotes protein storage. Plant J 2007, 51:468-484.
180. Rontein D., Dieuaide-Noubhani M., Dufourc Erick J., Raymond P., Rolin D. The metabolic architecture of plant cells. Stability of central metabolism and flexibility of anabolic pathway during the growth cycle of tomato cells. J Biol Chem 2002, 277:43948-43960.
181. Ryu C.M., Farag M.A., Hu C.H., Reddy M.S., Wei H.X., Pare P.W., et al. Bacterial volatiles promote growth in Arabidopsis. Proc Natl Acad Sci U S A 2003, 100:4927-4932.
182. Ryu C.M., Farag M.A., Hu C.H., Reddy M.S., Kloepper J.V., Pare P.W. Bacterial volatiles induce systemic resistance in Arabidopsis. Plant Physiol 2004, 134:1017-1026.
183. Sakulsingharoj C., Choi S.-B., Hwang S.-K., Edwards G.E., Bork J., Meyer C.R., et al. Engineering starch biosynthesis for increasing rice seed weight: the role of the cytoplasmic ADP-glucose pyrophosphorylase. Plant Sci 2004, 167:1323-1333.
184. Samaj J., Read N.D., Volkmann D., Menzel D., Baluska F. The endocytic network in plants. Trends Cell Biol 2005, 8:425-433.
185. Sanz-Barrio R., Corral-Martínez P., Ancin M., Segui-Simarro J.M., Farrán I. Overexpression of plastidial thioredoxin f leads to enhanced starch accumulation in tobacco leaves. Plant Biotechnol J 2013, 19:618-627.
186. Sauer N. Molecular physiology of higher plant sucrose transporters. FEBS Lett 2007, 581:2309-2317.
187. Schluepmann H., Pellny T., van Dijken A., Smeekens S., Paul M. Trehalose 6-phosphate is indispensable for carbohydrate utilization and growth in Arabidopsis thaliana. Proc Natl Acad Sci U S A 2003, 100:6849-6854.
188. Scofield G.N., Hirose T., Gaudron J.A., Upadhyaya N.M., Ohsugi R., Furbank R.T. Antisense suppression of the rice sucrose transporter gene, OsSUT1, leads to impaired grain filling and germination but does not affect photosynthesis. Funct Plant Biol 2002, 29:815-826.
189. Scott P., Kruger N.J. Influence of elevated fructose-2,6-bisphosphate levels on starch mobilization in transgenic tobacco leaves in the dark. Plant Physiol 1995, 108:1569-1577.
190. Serrato A.J., Pérez-Ruiz J.M., Spínola M.C., Cejudo F.J. A novel NADPH thioredoxin reductase, localized in the chloroplast, which deficiency causes hypersensitivity to abiotic stress in Arabidopsis thaliana. J Biol Chem 2004, 279:43821-43827.
191. Shannon J.C., Pien F.-M., Liu K.-C. Nucleotides and nucleotide sugars in developing maize endosperms. Synthesis of ADP-glucose in brittle 1. Plant Physiol 1996, 110:835-843.
192. Shannon J.C., Pien F.-M., Cao H., Liu K.-C. Brittle-1, an adenylate translocator, facilitates transfer of extraplastidial synthesized ADP-glucose into amyloplasts of maize endosperms. Plant Physiol 1998, 117:1235-1252.
193. She K.-C., Kusano H., Koizumi K., Yamakawa H., Hakata M., Imamura T., et al. A novel factor FLOURY ENDOSPERM2 is involved in regulation of rice grain size and starch quality. Plant Cell 2010, 22:3280-3294.
194. Shewmaker C.K., Boyer C.D., Wiesenborn D.P., Thompson D.B., Boersig M.R., Oakes J.V., et al. Expression of Escherichia coli glycogen synthase in the tubers of transgenic potatoes (Solanum tuberosum) results in a highly branched starch. Plant Physiol 1994, 104:1159-1166.
195. Silvius J.E., Snyder F.W. Comparative enzymic studies of sucrose metabolism in the taproots and fibrous roots of Beta vulgaris L. Plant Physiol 1979, 64:1070-1073.
196. Sivitz A.B., Reinders A., Ward J.M. Analysis of the transport activity of barley sucrose transporter HvSUT1. Plant Cell Physiol 2005, 46:1666-1673.
197. Slattery C.J., Kavakli I.H., Okita T.W. Engineering starch for increased quantity and quality. Trends Plant Sci 2000, 5:291-298.
198. Smidansky E.D., Clancy M., Meyer F.D., Lanning S.P., Blake N.K., Talbert L.E., et al. Enhanced ADP-glucose pyrophosphorylase activity in wheat endosperm increases seed yield. Proc Natl Acad Sci U S A 2002, 99:1724-1729.
199. Smidansky E.D., Martin J.M., Hannah L.C., Fischer A.M., Giroux M.J. Seed yield and plant biomass increases in rice are conferred by deregulation of endosperm ADP-glucose pyrophosphorylase. Planta 2003, 216:656-664.
200. Smith A.M. Prospects for increasing starch and sucrose yields for bioethanol production. Plant J 2008, 54:546-558.
201. Sonnewald U., Basner A., Greve B., Steup M. A second L-type isozyme of potato glucan phosphorylase: cloning, antisense inhibition and expression analysis. Plant Mol Biol 1995, 27:567-576.
202. Sparla F., Costa A., Lo Schiavo F., Pupillo P., Trost P. Redox regulation of a novel plastid-targeted β-amylase of Arabidopsis. Plant Physiol 2006, 141:840-850.
203. Splivallo R., Fischer U., Göbel C., Feussner I., Karlovsky P. Truffle volatiles inhibit growth and induce an oxidative burst in Arabidopsis thaliana. New Phytol 2007, 175:417-424.
204. Stark D.M., Timmerman K.P., Barry G.F., Preiss J., Kishore G.M. Regulation of the amount of starch in plant tissues by ADPglucose pyrophosphorylase. Science 1992, 258:287-292.
205. Stitt M., Heldt H.W. Simultaneous synthesis and degradation of starch in spinach chloroplasts in the light. Biochim Biophys Acta 1981, 638:1-11.
206. Stitt M., Zeeman S. Starch turnover: pathways, regulation and role in growth. Curr Opin Plant Biol 2012, 15:1-11.
207. Strand A., Zrenner R., Trevanion S., Stitt M., Gustafsson P., Gardeström P. Decreased expression of two key enzymes in the sucrose biosynthesis pathway, cytosolic fructose-1,6-bisphosphatase and sucrose phosphate synthase, has remarkably different consequences for photosynthetic carbon metabolism in transgenic Arabidopsis thaliana. Plant J 2000, 23:759-770.
208. Streb S., Zeeman S.C. Starch metabolism in Arabidopsis. The Arabidopsis book 2012, 10:e0160. 10.1199/tab.0160.
209. Streb S., Egli B., Eicke S., Zeeman S.C. The debate on the pathway of starch synthesis: a closer look at low-starch mutants lacking plastidial phosphoglucomutase supports the chloroplast-localised pathway. Plant Physiol 2009, 151:1769-1772.
210. Sulpice R., Pyl E.-T., Ishihara H., Trenkamp S., Steinfath M., Witucka-Wall H., et al. Starch as a major integrator in the regulation of plant growth. Proc Natl Acad Sci U S A 2009, 106:10348-10353.
211. Sweetlove L.J., Burrell M.M., ap Rees T. Starch metabolism in tubers of transgenic potato (Solanum tuberosum) with increased ADPglucose pyrophosphorylase. Biochem J 1996, 320:493-498.
212. Szydlowski N., Ragel P., Raynaud S., Roldán I., Montero M., Lucas M.M., et al. Starch granule initiation in Arabidopsis requires the presence of either class IV or class III starch synthase. Plant Cell 2009, 21:2443-2457.
213. Tacke M., Yang Y., Steup M. Multiplicity of soluble glucan-synthase activity in spinach leaves: enzyme pattern and intracellular location. Planta 1991, 185:220-226.
214. Tang G.-Q., Sturm A. Antisense repression of sucrose synthase in carrot (Daucus carota L.) affects growth rather than sucrose partitioning. Plant Mol Biol 1999, 41:465-479.
215. Tarkka M.T., Piechulla B. Aromatic weapons: truffles attack plants by the production of volatiles. New Phytol 2007, 175:381-383.
216. Tauberger E., Fernie A.R., Emmermann M., Renz A., Kossmann J., Willmitzer L., et al. Antisense inhibition of plastidial phosphoglucomutase provides compelling evidence that potato tuber amyloplasts import carbon from the cytosol in the form of glucose-6-phosphate. Plant J 2000, 23:43-53.
217. Thévenot C., Simond-CÔte E., Reyss A., Manicacci D., Trouverie J., Le Guilloux M., et al. QTLs for enzyme activities and soluble carbohydrates involved in starch accumulation during grain filling in maize. J Exp Bot 2005, 56:945-958.
218. Thormählen I., Ruber J., von Roepenack-Lahaye E., Ehrlich S.-M., Massot V., Hümmer C., et al. Inactivation of thioredoxin f1 leads to decreased light activation of ADP-glucose pyrophosphorylase and altered diurnal starch turnover in leaves of Arabidopsis plants. Plant Cell Environ 2013, 36:16-29.
219. ThornbjØrnsen T., Villand P., Denyer K., Olsen O.-A., Smith A.M. Distinct isoforms of ADPglucose pyrophosphorylase occur inside and outside the amyloplast in barley endosperm. Plant J 1996, 10:243-250.
220. ThornbjØrnsen T., Villand P., Kleczkowski L.A., Olsen O.A. A single gene encodes two different transcripts of ADP-glucose pyrophosphorylase small subunit from barley (Hordeum vulgare). Biochem J 1996, 313:149-154.
221. Tiessen A., Prescha K., Branscheid A., Palacios N., McKibbin R., Halford N.G., et al. Evidence that SNF1-related kinase and hexokinase are involved in separate sugar signaling pathways modulating post-translational redox activation of ADP-glucose pyrophosphorylase in potato tubers. Plant J 2003, 35:490-500.
222. Tiessen A., Nerlich A., Faix B., Hümmer C., Fox S., Trafford K., et al. Subcellular analysis of starch metabolism in developing barley seeds using a non-aqueous fractionation method. J Exp Bot 2012, 63:2071-2087.
223. Tjaden J., Möhlmann T., Kampfenkel K., Henrichs G., Neuhaus H.E. Altered plastidic ATP/ADP-transporter activity influences potato (Solanum tuberosum L.) tuber morphology, yield and composition of tuber starch. Plant J 1998, 16:531-540.
224. Trethewey R.N., Geigenberger P., Riedel K., Hajirezaei M.-R., Sonnewald U., Stitt M., et al. Combined expression of glucokinase and invertase in potato tubers leads to a dramatic reduction in starch accumulation and a stimulation of glycolysis. Plant J 1998, 15:109-118.
225. Trethewey R.N., Fernie A.R., Bachmann A., Fleischer-Notter H., Geigenberger P., Willmitzer L. Expression of a bacterial sucrose phosphorylase in potato tubers results in a glucose-independent induction of glycolysis. Plant Cell Environ 2001, 24:357-365.
226. Tsai C., Nelson O.E. Starch-deficient maize mutant lacking adenosine diphosphate glucose pyrophosphorylase activity. Science 1966, 151:341-343.
227. Tsai H.L., Lue W.L., Lu K.J., Hsieh M.H., Wang S.M., Chen J. Starch synthesis in Arabidopsis is achieved by spatial cotranscription of core starch metabolism genes. Plant Physiol 2009, 151:1582-1595.
228. Valerio C., Costa A., Marri L., Issakidis-Bourguet E., Pupillo P., Trost P., et al. Thioredoxin-regulated β-amylase (BAM1) triggers diurnal starch degradation in guard cells, and in mesophyll cells under osmotic stress. J Exp Bot 2010, 62:545-555.
229. Vargas W.A., Pontis H.G., Salerno G.L. New insights on sucrose metabolism: evidence for an active A/N-Inv in chloroplasts uncovers a novel component of the intracellular carbon trafficking. Planta 2008, 227:795-807.
230. Ventriglia T., Kuhn M.L., Ruiz M.T., Ribeiro-Pedro M., Valverde F., Ballicora M.A., et al. Two Arabidopsis ADP-glucose pyrophosphorylase large subunits (APL1 and APL2) are catalytic. Plant Physiol 2008, 148:65-76.
231. Vespermann A., Kai M., Piechulla B. Rhizobacterial volatiles affect the growth of fungi and Arabidopsis thaliana. Appl Environ Microbiol 2007, 73:5639-5641.
232. Villand P., Kleczkowski L.A. Is there an alternative pathway for starch biosynthesis in cereal seeds?. Z Naturforsch 1994, 49:215-219.
233. Viola R., Roberts A.G., Haupt S., Gazzani S., Hancock R.D., Marmiroli N., et al. Tuberization in potato involves a switch from apoplastic to symplastic phloem unloading. Plant Cell 2001, 13:385-398.
234. Walters R.G., Ibrahim D.G., Horton P., Kruger N.J. A mutant of Arabidopsis lacking the triose-phosphate/phosphate translocator reveals metabolic regulation of starch breakdown in the light. Plant Physiol 2004, 135:891-906.
235. Wang S.-M., Lue W.-L., Yu T.-S., Long J.-H., Wang C.-N., Eimert K., et al. Characterization of ADG1, an Arabidopsis locus encoding for ADPG pyrophosphorylase small subunit, demonstrates that the presence of the small subunit is required for large subunit stability. Plant J 1998, 13:63-70.
236. Wang A.-Y., Kao M.-H., Yang W.-H., Sayion Y., Liu L.-F., Lee P.-D., et al. Differentially and developmentally regulated expression of three rice sucrose synthase genes. Plant Cell Physiol 1999, 40:800-807.
237. Wang Z., Chen X., Wang J., Liu T., Liu Y., Zhao L., et al. Increasing maize seed weight by enhancing the cytoplasmic ADP-glucose pyrophosphorylase activity in transgenic maize plants. Plant Cell Tissue Organ 2007, 88:83-92.
238. Wang Y., Yu B., Zhao J., Guo J., Li Y., Han S., et al. Autophagy contributes to leaf starch degradation. Plant Cell 2013, 25:1383-1399.
239. Weber H., Heim U., Borisjuk L., Wobus U. Cell-type specific, coordinate expression of two ADP-glucose pyrophosphorylase genes in relation to starch biosynthesis during seed development of Vicia faba. Planta 1995, 195:352-361.
240. Weber H., Rolletschek H., Heim U., Golombek S., Gubatz S., Wobus U. Antisense-inhibition of ADP-glucose pyrophosphorylase in developing seeds of Vicia narbonensis moderately decreases starch but increases protein content and affects seed maturation. Plant J 2000, 24:33-43.
241. Weichert N., Saalbach I., Weichert H., Kohl S., Erban A., Kopka J., et al. Increasing sucrose uptake capacity of wheat grains stimulates storage protein synthesis. Plant Physiol 2010, 152:698-710.
242. Weschke W., Panitz R., Sauer N., Wang Q., Neubohn B., Weber H., et al. Sucrose transport into barley seeds: molecular characterization of two transporters and implications for seed development and starch accumulation. Plant J 2000, 21:455-467.
243. Yu T.-S., Lue W.-L., Wang S.-M., Chen J. Mutation of Arabidopsis plastid phosphoglucose isomerase affects leaf starch synthesis and floral initiation. Plant Physiol 2000, 123:319-325.
244. Zeeman S.C., Thorneycroft D., Schupp N., Chapple A., Weck M., Dunstan H., et al. Plastidial α-glucan phosphorylase is not required for starch degradation in Arabidopsis leaves but has a role in the tolerance of abiotic stress. Plant Physiol 2004, 135:849-858.
245. Zervosen A., Römer U., Elling L. Application of recombinant sucrose synthase-large scale synthesis of ADP-glucose. J Mol Catal 1998, 5:25-28.
246. Zhang L., Häusler R.E., Greiten C., Hajirezaei M.-R., Haferkamp I., Neuhaus H.E., et al. Overriding the co-limiting import of carbon and energy into tuber amyloplasts increases the starch content and yield of transgenic potato plants. Plant Biotechnol J 2008, 6:453-464.
247. Zhang H., Xie X., Kim M.-S., Kornyeyev D.A., Holaday S., Paré P.W. Soil bacteria augment Arabidopsis photosynthesis by decreasing glucose sensing and abscisic acid levels in planta. Plant J 2008, 56:264-273.
248. Zhang H., Sun Y., Xie X., Kim M.-S., Dowd S.E., Paré P.W. A soil bacterium regulates plant acquisition of iron via deficiency-inducible mechanisms. Plant J 2009, 58:568-577.
249. Zhang Y., Primavesi L.F., Jhurreea D., Andralojc P.J., Mitchell R.A., Powers S.J., et al. Inhibition of SNF1-related protein kinase 1 activity and regulation of metabolic pathways by trehalose-6-phosphate. Plant Physiol 2009, 149:1860-1871.
250. Zhou R., Cheng L. Competitive inhibition of phosphoglucose isomerase of apple leaves by sorbitol 6-phosphate. J Plant Physiol 2008, 165:903-910.
251. Zrenner R., Willmitzer L., Sonnewald U. Analysis of the expression of potato uridinediphosphate-glucose pyrophosphorylase and its inhibition by antisense RNA. Planta 1993, 190:247-252.
252. Zrenner R., Salanoubat M., Willmitzer L., Sonnewald U. Evidence of the crucial role of sucrose synthase for sink strength using transgenic potato plants (Solanum tuberosum L.). Plant J 1995, 7:97-107.