Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 2, 2014, Pages

  Lluis, Anna ^a   Depner, Martin ^a   Gaugler, Beatrice ^b   Saas, Philippe ^b   Casaca, Vera Isabel ^a   Raedler, Diana ^a   Michel, Sven ^c   Tost, Jorg ^d   Liu, Jing ^a,e   Genuneit, Jon ^f   Pfefferle, Petra ^g   Roponen, Marjut ^h   Weber, Juliane ^a   Braun Fahrländer, Charlotte ^i,j   Riedler, Josef ^k   Lauener, Roger ^l   Vuitton, Dominique Angèle ^m   Dalphin, Jean Charles ^m   Pekkanen, Juha ^h,n   Von Mutius, Erika ^a   Schaub, Bianca ^a   more..

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL OF BESANÇON   (France)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^e THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^f UNIVERSITY OF ULM   (Germany)

^g PHILIPPS UNIVERSITY MARBURG   (Germany)

^h UNIVERSITY OF EASTERN FINLAND   (Finland)

ⁱ SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^j UNIVERSITY OF BASEL   (Switzerland)

^k Schwarzach Hospital   (Austria)

^l Christine Kühne Center for Allergy Research and Education   (Switzerland)

^m UNIVERSITÉ DE FRANCHE COMTÉ   (France)

ⁿ NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

more..

Author keywords

Asthma; atopic sensitization; farming; FOXP3 demethylation; innate; milk; peripheral blood mononuclear cells; regulatory T cells

Indexed keywords

IMMUNOGLOBULIN E; IONOMYCIN; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR FOXP3;

AGRICULTURAL LAND; AGRICULTURAL WORKER; ALLERGIC DISEASE; ARTICLE; ASTHMA; ATOPY; CD4+ CD25+ T LYMPHOCYTE; CHILD; CHILDHOOD DISEASE; HUMAN; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MILK; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; REGULATORY T LYMPHOCYTE; SENSITIZATION; T LYMPHOCYTE ACTIVATION;

ALEX; ALLERGY AND ENDOTOXIN STUDY; ASTHMA; ATOPIC SENSITIZATION; EFRAIM; FARMING; FITC; FLUORESCEIN ISOTHIOCYANATE; FORKHEAD BOX PROTEIN 3; FOXP3; FOXP3 DEMETHYLATION; INNATE; MECHANISMS OF EARLY PROTECTIVE EXPOSURES ON ALLERGY DEVELOPMENT; MILK; ODDS RATIO; OR; PARSIFAL; PASTURE; PE; PERIPHERAL BLOOD MONONUCLEAR CELLS; PHORBOL 12-MYRISTATE 13-ACETATE/IONOMYCIN; PHYCOERYTHRIN; PI; PREVENTION OF ALLERGY-RISK FACTORS FOR SENSITIZATION IN CHILDREN RELATED TO FARMING AND ANTHROPOSOPHIC LIFESTYLE; PROTECTION AGAINST ALLERGY: STUDY IN RURAL ENVIRONMENTS; REGULATORY T; REGULATORY T CELLS; SIC; SPECIFIC IGE CLASS; TLR; TOLL-LIKE RECEPTOR; TREG;

AGRICULTURE; ANIMALS; ASTHMA; CD4 LYMPHOCYTE COUNT; CHILD, PRESCHOOL; DNA METHYLATION; EUROPE; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; INFANT; MALE; MILK; PREGNANCY; PROSPECTIVE STUDIES; T-LYMPHOCYTES, REGULATORY;

EID: 84895057230     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.06.034     Document Type: Article

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