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Volumn 35, Issue 9, 2014, Pages 2961-2970

Multimodal SPION-CREKA peptide based agents for molecular imaging of microthrombus in a rat myocardial ischemia-reperfusion model

Author keywords

APTT; CREKA; FFP; Fibrin; Magnetic resonance imaging; MI R; Microthrombosis; MRI; Multimodal nanoagents; Optical imaging; PEG; PT; SPION; TT

Indexed keywords

FIBRIN; MAGNETIC RESONANCE IMAGING; MICROTHROMBOSIS; MULTIMODAL NANOAGENTS; OPTICAL IMAGING;

EID: 84895002003     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.038     Document Type: Article
Times cited : (78)

References (42)
  • 1
    • 0033573539 scopus 로고    scopus 로고
    • Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats
    • Zhang Z.G., Chopp M., Goussev A., Lu D., Morris D., Tsang W., et al. Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats. J Neurosci 1999, 19:10898-10907.
    • (1999) J Neurosci , vol.19 , pp. 10898-10907
    • Zhang, Z.G.1    Chopp, M.2    Goussev, A.3    Lu, D.4    Morris, D.5    Tsang, W.6
  • 2
    • 0031660781 scopus 로고    scopus 로고
    • Mechanisms of cerebrovascular events as assessed by procoagulant activity, cerebral microemboli, and platelet microparticles in patients with prosthetic heart valves
    • Geiser T., Sturzenegger M., Genewein U., Haeberli A., Beer J.H. Mechanisms of cerebrovascular events as assessed by procoagulant activity, cerebral microemboli, and platelet microparticles in patients with prosthetic heart valves. Stroke 1998, 29:1770-1777.
    • (1998) Stroke , vol.29 , pp. 1770-1777
    • Geiser, T.1    Sturzenegger, M.2    Genewein, U.3    Haeberli, A.4    Beer, J.H.5
  • 3
    • 0029880131 scopus 로고    scopus 로고
    • Microthromboemboli in acute infarcts: analysis of 40 autopsy cases
    • Heye N., Cervos-Navarro J. Microthromboemboli in acute infarcts: analysis of 40 autopsy cases. Stroke 1996, 27:431-434.
    • (1996) Stroke , vol.27 , pp. 431-434
    • Heye, N.1    Cervos-Navarro, J.2
  • 4
    • 0034711124 scopus 로고    scopus 로고
    • Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction
    • Ojio S., Takatsu H., Tanaka T., Ueno K., Yokoya K., Matsubara T., et al. Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction. Circulation 2000, 102:2063-2069.
    • (2000) Circulation , vol.102 , pp. 2063-2069
    • Ojio, S.1    Takatsu, H.2    Tanaka, T.3    Ueno, K.4    Yokoya, K.5    Matsubara, T.6
  • 5
    • 4243595807 scopus 로고
    • Myocardial reperfusion injury. Histopathological effects of perfluorochemical
    • Virmani R., Forman M.B., Kolodgie F.D. Myocardial reperfusion injury. Histopathological effects of perfluorochemical. Circulation 1990, 81:IV57-IV68.
    • (1990) Circulation , vol.81
    • Virmani, R.1    Forman, M.B.2    Kolodgie, F.D.3
  • 6
    • 77950573904 scopus 로고    scopus 로고
    • Microvascular obstruction: underlying pathophysiology and clinical diagnosis
    • Bekkers S.C., Yazdani S.K., Virmani R., Waltenberger J. Microvascular obstruction: underlying pathophysiology and clinical diagnosis. J Am Coll Cardiol 2010, 55:1649-1660.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1649-1660
    • Bekkers, S.C.1    Yazdani, S.K.2    Virmani, R.3    Waltenberger, J.4
  • 7
    • 84871536298 scopus 로고    scopus 로고
    • The significance of microthrombosis and fgl2 in no-reflow phenomenon of rats with acute myocardial ischemia/reperfusion
    • Shao L., Wu D., Zhang P., Li W., Wang J., Su G., et al. The significance of microthrombosis and fgl2 in no-reflow phenomenon of rats with acute myocardial ischemia/reperfusion. Clin Appl Thromb Hemost 2013, 19:19-28.
    • (2013) Clin Appl Thromb Hemost , vol.19 , pp. 19-28
    • Shao, L.1    Wu, D.2    Zhang, P.3    Li, W.4    Wang, J.5    Su, G.6
  • 8
    • 84893571250 scopus 로고    scopus 로고
    • No-reflow phenomenon: pathophysiology, diagnosis, prevention, and treatment. A review of the current literature and future perspectives
    • Available from URL:
    • Galasso G., Schiekofer S., D'Anna C., Di Gioia G., Piccolo R., Niglio T., et al. No-reflow phenomenon: pathophysiology, diagnosis, prevention, and treatment. A review of the current literature and future perspectives. Angiology 2013, http;//dx.doi.org/10.1177/0003319712474336. Available from URL: http://www.ncbi.nlm.nih.gov/pubmed/23362304.
    • (2013) Angiology
    • Galasso, G.1    Schiekofer, S.2    D'Anna, C.3    Di Gioia, G.4    Piccolo, R.5    Niglio, T.6
  • 9
    • 33847231568 scopus 로고    scopus 로고
    • Coronary microvascular dysfunction
    • Camici P.G., Crea F. Coronary microvascular dysfunction. N Engl J Med 2007, 356:830-840.
    • (2007) N Engl J Med , vol.356 , pp. 830-840
    • Camici, P.G.1    Crea, F.2
  • 10
    • 79959690297 scopus 로고    scopus 로고
    • Microvascular coronary dysfunction in women: pathophysiology, diagnosis, and management
    • Kothawade K., Bairey Merz C.N. Microvascular coronary dysfunction in women: pathophysiology, diagnosis, and management. Curr Probl Cardiol 2011, 36:291-318.
    • (2011) Curr Probl Cardiol , vol.36 , pp. 291-318
    • Kothawade, K.1    Bairey Merz, C.N.2
  • 11
    • 44849144688 scopus 로고    scopus 로고
    • Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons
    • Shimizu A., Hisashi Y., Kuwaki K., Tseng Y.L., Dor F.J., Houser S.L., et al. Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol 2008, 172:1471-1481.
    • (2008) Am J Pathol , vol.172 , pp. 1471-1481
    • Shimizu, A.1    Hisashi, Y.2    Kuwaki, K.3    Tseng, Y.L.4    Dor, F.J.5    Houser, S.L.6
  • 12
    • 0035845635 scopus 로고    scopus 로고
    • Novel MRI contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaques
    • Flacke S., Fischer S., Scott M.J., Fuhrhop R.J., Allen J.S., McLean M., et al. Novel MRI contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaques. Circulation 2001, 104:1280-1285.
    • (2001) Circulation , vol.104 , pp. 1280-1285
    • Flacke, S.1    Fischer, S.2    Scott, M.J.3    Fuhrhop, R.J.4    Allen, J.S.5    McLean, M.6
  • 13
    • 0033646270 scopus 로고    scopus 로고
    • High-resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent
    • Yu X., Song S.K., Chen J., Scott M.J., Fuhrhop R.J., Hall C.S., et al. High-resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent. Magn Reson Med 2000, 44:867-872.
    • (2000) Magn Reson Med , vol.44 , pp. 867-872
    • Yu, X.1    Song, S.K.2    Chen, J.3    Scott, M.J.4    Fuhrhop, R.J.5    Hall, C.S.6
  • 14
    • 75149168815 scopus 로고    scopus 로고
    • Near-infrared fluorescence: application to in vivo molecular imaging
    • Hilderbrand S.A., Weissleder R. Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol 2010, 14:71-79.
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 71-79
    • Hilderbrand, S.A.1    Weissleder, R.2
  • 15
    • 33846101945 scopus 로고    scopus 로고
    • Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging
    • Flaumenhaft R., Tanaka E., Graham G.J., De Grand A.M., Laurence R.G., Hoshino K., et al. Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging. Circulation 2007, 115:84-93.
    • (2007) Circulation , vol.115 , pp. 84-93
    • Flaumenhaft, R.1    Tanaka, E.2    Graham, G.J.3    De Grand, A.M.4    Laurence, R.G.5    Hoshino, K.6
  • 16
    • 1542313912 scopus 로고    scopus 로고
    • Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels
    • Sim D.S., Merrill-Skoloff G., Furie B.C., Furie B., Flaumenhaft R. Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. Blood 2004, 103:2127-2134.
    • (2004) Blood , vol.103 , pp. 2127-2134
    • Sim, D.S.1    Merrill-Skoloff, G.2    Furie, B.C.3    Furie, B.4    Flaumenhaft, R.5
  • 19
    • 0033755390 scopus 로고    scopus 로고
    • Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology
    • Brigger I., Chaminade P., Desmaele D., Peracchia M.T., d'Angelo J., Gurny R., et al. Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology. Pharm Res 2000, 17:1124-1132.
    • (2000) Pharm Res , vol.17 , pp. 1124-1132
    • Brigger, I.1    Chaminade, P.2    Desmaele, D.3    Peracchia, M.T.4    d'Angelo, J.5    Gurny, R.6
  • 20
    • 84885371788 scopus 로고    scopus 로고
    • The effect of nonuniform magnetic targeting of intracoronary-delivering mesenchymal stem cells on coronary embolisation
    • Huang Z., Shen Y., Pei N., Sun A., Xu J., Song Y., et al. The effect of nonuniform magnetic targeting of intracoronary-delivering mesenchymal stem cells on coronary embolisation. Biomaterials 2013, 34:9905-9916.
    • (2013) Biomaterials , vol.34 , pp. 9905-9916
    • Huang, Z.1    Shen, Y.2    Pei, N.3    Sun, A.4    Xu, J.5    Song, Y.6
  • 21
    • 0032528494 scopus 로고    scopus 로고
    • Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin
    • Massberg S., Enders G., Leiderer R., Eisenmenger S., Vestweber D., Krombach F., et al. Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood 1998, 92:507-515.
    • (1998) Blood , vol.92 , pp. 507-515
    • Massberg, S.1    Enders, G.2    Leiderer, R.3    Eisenmenger, S.4    Vestweber, D.5    Krombach, F.6
  • 22
    • 0029142532 scopus 로고
    • Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil
    • Jung C.W., Jacobs P. Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil. Magn Reson Imaging 1995, 13:661-674.
    • (1995) Magn Reson Imaging , vol.13 , pp. 661-674
    • Jung, C.W.1    Jacobs, P.2
  • 23
    • 0029080022 scopus 로고
    • Surface properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil
    • Jung C.W. Surface properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil. Magn Reson Imaging 1995, 13:675-691.
    • (1995) Magn Reson Imaging , vol.13 , pp. 675-691
    • Jung, C.W.1
  • 25
    • 2942514778 scopus 로고    scopus 로고
    • Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding
    • Keselowsky B.G., Collard D.M., Garcia A.J. Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding. Biomaterials 2004, 25:5947-5954.
    • (2004) Biomaterials , vol.25 , pp. 5947-5954
    • Keselowsky, B.G.1    Collard, D.M.2    Garcia, A.J.3
  • 26
    • 78649522496 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy
    • Mahmoudi M., Sant S., Wang B., Laurent S., Sen T. Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy. Adv Drug Deliv Rev 2011, 63:24-46.
    • (2011) Adv Drug Deliv Rev , vol.63 , pp. 24-46
    • Mahmoudi, M.1    Sant, S.2    Wang, B.3    Laurent, S.4    Sen, T.5
  • 27
    • 0033485324 scopus 로고    scopus 로고
    • Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo
    • Massberg S., Enders G., Matos F.C., Tomic L.I., Leiderer R., Eisenmenger S., et al. Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo. Blood 1999, 94:3829-3838.
    • (1999) Blood , vol.94 , pp. 3829-3838
    • Massberg, S.1    Enders, G.2    Matos, F.C.3    Tomic, L.I.4    Leiderer, R.5    Eisenmenger, S.6
  • 29
  • 30
    • 84855801985 scopus 로고    scopus 로고
    • Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting
    • Li M.H., Choi S.K., Thomas T.P., Desai A., Lee K.H., Kotlyar A., et al. Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem 2012, 47:560-572.
    • (2012) Eur J Med Chem , vol.47 , pp. 560-572
    • Li, M.H.1    Choi, S.K.2    Thomas, T.P.3    Desai, A.4    Lee, K.H.5    Kotlyar, A.6
  • 31
    • 24944489153 scopus 로고    scopus 로고
    • Chronic thrombus detection with in vivo magnetic resonance imaging and a fibrin-targeted contrast agent
    • Sirol M., Fuster V., Badimon J.J., Fallon J.T., Moreno P.R., Toussaint J.F., et al. Chronic thrombus detection with in vivo magnetic resonance imaging and a fibrin-targeted contrast agent. Circulation 2005, 112:1594-1600.
    • (2005) Circulation , vol.112 , pp. 1594-1600
    • Sirol, M.1    Fuster, V.2    Badimon, J.J.3    Fallon, J.T.4    Moreno, P.R.5    Toussaint, J.F.6
  • 32
    • 23944477851 scopus 로고    scopus 로고
    • Fibrin-targeted contrast agent for improvement of in vivo acute thrombus detection with magnetic resonance imaging
    • Sirol M., Aguinaldo J.G., Graham P.B., Weisskoff R., Lauffer R., Mizsei G., et al. Fibrin-targeted contrast agent for improvement of in vivo acute thrombus detection with magnetic resonance imaging. Atherosclerosis 2005, 182:79-85.
    • (2005) Atherosclerosis , vol.182 , pp. 79-85
    • Sirol, M.1    Aguinaldo, J.G.2    Graham, P.B.3    Weisskoff, R.4    Lauffer, R.5    Mizsei, G.6
  • 33
    • 42949106036 scopus 로고    scopus 로고
    • EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus
    • Overoye-Chan K., Koerner S., Looby R.J., Kolodziej A.F., Zech S.G., Deng Q., et al. EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus. J Am Chem Soc 2008, 130:6025-6039.
    • (2008) J Am Chem Soc , vol.130 , pp. 6025-6039
    • Overoye-Chan, K.1    Koerner, S.2    Looby, R.J.3    Kolodziej, A.F.4    Zech, S.G.5    Deng, Q.6
  • 34
    • 49149111290 scopus 로고    scopus 로고
    • Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis
    • von zur Muhlen C., von Elverfeldt D., Moeller J.A., Choudhury R.P., Paul D., Hagemeyer C.E., et al. Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis. Circulation 2008, 118:258-267.
    • (2008) Circulation , vol.118 , pp. 258-267
    • Von Zur Muhlen, C.1    von Elverfeldt, D.2    Moeller, J.A.3    Choudhury, R.P.4    Paul, D.5    Hagemeyer, C.E.6
  • 36
    • 77953160474 scopus 로고    scopus 로고
    • Molecular MRI of intracranial thrombus in a rat ischemic stroke model
    • Uppal R., Ay I., Dai G., Kim Y.R., Sorensen A.G., Caravan P. Molecular MRI of intracranial thrombus in a rat ischemic stroke model. Stroke 2010, 41:1271-1277.
    • (2010) Stroke , vol.41 , pp. 1271-1277
    • Uppal, R.1    Ay, I.2    Dai, G.3    Kim, Y.R.4    Sorensen, A.G.5    Caravan, P.6
  • 37
    • 80054727258 scopus 로고    scopus 로고
    • Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy
    • Tassa C., Shaw S.Y., Weissleder R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res 2011, 44:842-852.
    • (2011) Acc Chem Res , vol.44 , pp. 842-852
    • Tassa, C.1    Shaw, S.Y.2    Weissleder, R.3
  • 38
    • 0034753215 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging
    • Wang Y.X., Hussain S.M., Krestin G.P. Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging. Eur Radiol 2001, 11:2319-2331.
    • (2001) Eur Radiol , vol.11 , pp. 2319-2331
    • Wang, Y.X.1    Hussain, S.M.2    Krestin, G.P.3
  • 39
    • 77149180096 scopus 로고    scopus 로고
    • Super paramagnetic iron oxide MRI shows defective Kupffer cell uptake function in non-alcoholic fatty liver disease
    • Asanuma T., Ono M., Kubota K., Hirose A., Hayashi Y., Saibara T., et al. Super paramagnetic iron oxide MRI shows defective Kupffer cell uptake function in non-alcoholic fatty liver disease. Gut 2010, 59:258-266.
    • (2010) Gut , vol.59 , pp. 258-266
    • Asanuma, T.1    Ono, M.2    Kubota, K.3    Hirose, A.4    Hayashi, Y.5    Saibara, T.6
  • 41
    • 15244345941 scopus 로고    scopus 로고
    • The MET oncogene drives a genetic programme linking cancer to haemostasis
    • Boccaccio C., Sabatino G., Medico E., Girolami F., Follenzi A., Reato G., et al. The MET oncogene drives a genetic programme linking cancer to haemostasis. Nature 2005, 434:396-400.
    • (2005) Nature , vol.434 , pp. 396-400
    • Boccaccio, C.1    Sabatino, G.2    Medico, E.3    Girolami, F.4    Follenzi, A.5    Reato, G.6
  • 42
    • 84855862357 scopus 로고    scopus 로고
    • In vivo near-infrared imaging of fibrin deposition in thromboembolic stroke in mice
    • Zhang Y., Fan S., Yao Y., Ding J., Wang Y., Zhao Z., et al. In vivo near-infrared imaging of fibrin deposition in thromboembolic stroke in mice. PLoS One 2012, 7:e30262.
    • (2012) PLoS One , vol.7
    • Zhang, Y.1    Fan, S.2    Yao, Y.3    Ding, J.4    Wang, Y.5    Zhao, Z.6


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