Bone regeneration using photocrosslinked hydrogel incorporating rhBMP-2 loaded 2-N, 6-O-sulfated chitosan nanoparticles

Biomaterials

Volumn 35, Issue 9, 2014, Pages 2730-2742

  Cao, Lingyan ^a,b,c   Werkmeister, Jerome A ^b   Wang, Jing ^a,c   Glattauer, Veronica ^b   McLean, Keith M ^b   Liu, Changsheng ^a,c,d  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CSIRO   (Australia)

^c East China University of Science and Technology   (China)

^d East China University of Science and Technology   (China)

Author keywords

BMP; Bone regeneration; Hydrogel; Nanoparticle

Indexed keywords

ALKALINITY; ANIMALS; BIOACTIVITY; CELL ADHESION; CELLS; CHITOSAN; COMPUTERIZED TOMOGRAPHY; DEFECTS; GROWTH KINETICS; HYDROGELS; NANOPARTICLES; PHOSPHATASES; REPAIR; TISSUE REGENERATION;

ALKALINE PHOSPHATASE ACTIVITY; BIOMECHANICAL MEASUREMENT; BONE REGENERATION; BONE TISSUE ENGINEERING; CHITOSAN NANOPARTICLES; ECTOPIC BONE FORMATIONS; MINERALIZATION ASSAYS; PHYSICAL CHARACTERIZATION;

BONE;

ALKALINE PHOSPHATASE; CHITOSAN; NANOPARTICLE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; BONE DEFECT; BONE MARROW; BONE MINERALIZATION; BONE PROSTHESIS; BONE REGENERATION; BONE REMODELING; BONE TISSUE; CELL ADHESION; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; PH; POLYMERIZATION; PRIORITY JOURNAL; RABBIT; RADIUS; SCANNING ELECTRON MICROSCOPY; SULFATION; SURFACE PROPERTY; THIGH; TISSUE ENGINEERING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

BMP; BONE REGENERATION; HYDROGEL; NANOPARTICLE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMECHANICAL PHENOMENA; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CALCIFICATION, PHYSIOLOGIC; CELL ADHESION; CELL SURVIVAL; CHITOSAN; CHORISTOMA; COCULTURE TECHNIQUES; COMPRESSIVE STRENGTH; CROSS-LINKING REAGENTS; DIAPHYSES; HUMANS; HYDROGEL; KINETICS; LIGHT; MALE; MICE; MUSCLES; NANOPARTICLES; OSTEOGENESIS; RABBITS; RECOMBINANT PROTEINS; SPECTROMETRY, X-RAY EMISSION; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA;

EID: 84894977390     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.028     Document Type: Article

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