Insulin-like growth factor-I receptor inhibition by specific tyrosine kinase inhibitor NVP-AEW541 in endometrioid and serous papillary endometrial cancer cell lines

Gynecologic Oncology

Volumn 121, Issue 2, 2011, Pages 383-389

  Attias Geva, Zohar ^a   Bentov, Itay ^a   Fishman, Ami ^b   Werner, Haim ^a   Bruchim, Ilan ^b  

^a TEL AVIV UNIVERSITY   (Israel)

^b MEIR MEDICAL CENTER   (Israel)

Author keywords

Endometrial cancer; IGF I receptor; Insulin like growth factor I (IGF I); Targeted therapy; Uterine serous papillary carcinoma (USPC)

Indexed keywords

INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NVP AEW 541; PROTEIN KINASE B; SOMATOMEDIN C;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; ENDOMETRIUM CANCER; GYNECOLOGIC CANCER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEROUS PAPILLARY ENDOMETRIAL CANCER;

APOPTOSIS; CARCINOMA, ENDOMETRIOID; CARCINOMA, PAPILLARY; CELL CYCLE; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CYSTADENOCARCINOMA, SEROUS; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MOLECULAR TARGETED THERAPY; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 79955479523     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.01.008     Document Type: Article

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