Coordinated regulation of serum-andglucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex

Journal of Biological Chemistry

Volumn 289, Issue 8, 2014, Pages 4815-4826

  Wang, Yuanzhong ^a   Xu, Wanping ^b   Zhou, Dujin ^a   Neckers, Len ^b   Chen, Shiuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; HYDROPHOBICITY;

HYDROPHOBIC MOTIFS;

COORDINATION REACTIONS;

CELL CYCLE PROTEIN 37; CHAPERONE; HEAT SHOCK PROTEIN 90; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN SERINE THREONINE KINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 3; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE TRANSPORT; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME REGULATION; HUMAN; HYDROPHOBICITY; MOUSE; NEOPLASM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

CDC37; CHIP; HSP90; HYDROPHOBIC MOTIF; MOLECULAR CHAPERONE; PI 3-KINASE (PI3K); PROTEIN STABILITY; SGK3; UBIQUITINATION;

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES; AMINO ACID MOTIFS; ANIMALS; BENZOQUINONES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CHAPERONINS; CHROMATOGRAPHY, LIQUID; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; ENZYME STABILITY; ESTROGENS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LACTAMS, MACROCYCLIC; MASS SPECTROMETRY; MICE; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84894472524     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.518480     Document Type: Article

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