CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4

EMBO Journal

Volumn 25, Issue 16, 2006, Pages 3738-3749

  Slagsvold, Thomas ^a   Marchese, Adriano ^b   Brech, Andreas ^a   Stenmark, Harald ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Chemokine receptor; Endocytosis; Lysosome; PI 3 kinase; Ubiquitin

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CYTOKINE INDEPENDENT SURVIVAL KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; LIGAND; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DEPENDENT KINASE 1; PHOSPHOTRANSFERASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE AIP4; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENDOSOME; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; LYSOSOME; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UPREGULATION;

AMINO ACID SEQUENCE; ENDOSOMES; ENZYME ACTIVATION; HELA CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; LYSOSOMES; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; RECEPTORS, CXCR4; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 33748041667     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601267     Document Type: Article

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