Crosstalk between mitochondrial ROS and depolarization in the potentiation of TRAIL-induced apoptosis in human tumor cells

International Journal of Oncology

Volumn 44, Issue 2, 2014, Pages 616-628

  Suzuki Karasaki, Miki ^a   Ochiai, Toyoko ^a   Suzuki Karasaki, Yoshihiro ^a,b  

^a NIHON UNIVERSITY   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; ATP sensitive potassium; Depolarization; K+; Mitochondria; Reactive oxygen species; Tumor necrosis factor related apoptosis inducing ligand

Indexed keywords

APOPTOSIS; BLOTTING, WESTERN; CARDIOLIPINS; CASPASE 12; CASPASE 3; CASPASE 7; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEOPLASMS; REACTIVE OXYGEN SPECIES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED;

EID: 84894428398     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2215     Document Type: Article

References (36)

1. LeBlanc HN and Ashkenazi A: Apo2L/TRAIL and its death and decoy. Cell Death Differ 10: 66-75, 2003.
2. Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ and Ashkenazi A: Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12: 612-620, 2000.
3. Lavrik IN, Golks A and Krammer PH: Caspases: pharmacological manipulation of cell death. J Clin Invest 15: 2665-2662, 2005.
4. Danial NN and Korsmeyer SJ: Cell death: critical control points. Cell 116: 205-219, 2014.
5. Green DR: Apoptotic pathways: paper wraps stone blunts scissors. Cell 102: 1-4, 2000.
6. Korsmeyer SJ, Wei MC, Saito, M, Weiler S, Oh KJ and Schlesinger PH: Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 7: 1166-1173, 2000. (Pubitemid 32042223)
7. Yan N and Shi Y: Mechanisms of apoptosis through structural biology. Annu Rev Cell Dev Biol 21: 35-56, 2005. (Pubitemid 41740626)
8. Dyer MJ, MacFarlane M and Cohen GM: Barriers to effective TRAIL-targeted therapy of malignancy. J Clin Oncol 25: 4506-4507, 2007.
9. Bortner CD, Gomez-Angelats M and Cidlowski JA: Plasma membrane depolarization without repolarization is an early molecular event in anti-Fas-induced apoptosis. J Biol Chem 276: 4304-4314, 2001.
10. Yin W, Li X, Feng S, et al: Plasma membrane depolarization and Na,K-ATPase impairment induced by mitochondrial toxins augment leukemia cell apoptosis via a novel mitochondrial amplification mechanism. Biochem Pharmacol 78: 191-202, 2009.
11. 3)-and anti-CD95-induced apoptosis in myeloid cells. FEBS Lett 578: 85-89, 2004.
12. Ghoumari AM, Piochon C, Tomkiewicz C, et al: Neuroprotective effect of mifepristone involves neuron depolarization. FASEB J 20: 1377-1386, 2006. (Pubitemid 44943846)
13. + channels and endoplasmic reticulum stress. Int J Oncol 41: 465-475, 2012.
14. Inoue, T and Suzuki-Karasaki Y: Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells. Free Radic Biol Med 61: 273-284, 2013.
15. Chen LH, Jiang CC, Kiejda KA, et al: Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response. Carcinogenesis 28: 2328-2336, 2007. (Pubitemid 350111591)
16. Jiang CC, Chen LH, Gillespie S, et al: Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response. Cancer Res 67: 5880-5888, 2007. (Pubitemid 46985023)
17. Liu H, Jiang CC, Lavis CJ, et al: 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2. Mol Cancer 8: 122, 2009.
18. Boyce M and Yuan J: Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13: 363-373, 2006.
19. Breckenridge DG, Germain M, Mathai JP, Nguyen M and Shore GC: Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22: 8608-8618, 2003. (Pubitemid 38019196)
20. Groenendyk J and Michalak M: Endoplasmic reticulum quality control and apoptosis. Acta Biochim Pol 52: 381-395, 2005. (Pubitemid 41133773)
21. Robinson KM, Janes MS, Pehar M, et al: Selective fluorescencet imaging of superoxide in vivo using ethidium-based probes. Proc Natl Acad Sci USA 103: 15038-15043, 2006. (Pubitemid 44583160)
22. Mukhopadhyay P, Rajesh M, Kashiwaya Y, Haskó G and Pacher P: Simple quantitative detection of mitochondrial superoxide production in live cells. Biochem Biophys Res Commun 358: 203-208, 2007. (Pubitemid 46719103)
23. Petit JM, Maftah A, Ratinaud MH and Julien R: 10N-nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur J Biochem 209: 267-273, 1992.
24. Griffith TS, Rauch CT, Smolak PJ, et al: Functional analysis of TRAIL receptors using monoclonal antibodies. J Immunol 162: 2597-2605, 1999. (Pubitemid 29309279)
25. Pukac L, Kanakaraj P, Humphreys R, et al: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. Br J Cancer 92: 1430-1441, 2005. (Pubitemid 40705010)
26. Georgakis GV, Li Y, Humphreys R, et al: Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death. Br J Haematol 130: 501-510, 2005. (Pubitemid 43899752)
27. Tochigi M, Inoue T, Suzuki-Karasaki M, Ochiai T, Ra C and Suzuki-Karasaki Y: Hydrogen peroxide induces cell death in human TRAIL-resistant melanoma through intracellular superoxide generation. Int J Oncol 42: 863-872, 2013.
28. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA and Yuan J: Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid beta. Nature 403: 98-103, 2000. (Pubitemid 30038529)
29. Szegezdi E, Fitzgerald U and Samali A: Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann NY Acad Sci 1010: 186-194, 2003. (Pubitemid 38264973)
30. Rutkowski DT and Kaufman RJ: A trip to the ER: coping with stress. Trends Cell Biol 14: 20-28, 2004. (Pubitemid 38076857)
31. Jiang CC, Mao ZG, Avery-Kiejda KA, Wade M, Hersey P and Zhang XD: Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells. Carcinogenesis 30: 197-204, 2009.
32. Mao ZG, Jiang CC, Yang F, Thorne RF, Hersey P and Zhang XD: TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4. Apoptosis 15: 1211-1222, 2010.
33. Fas SC, Baumann S, Zhu JY, et al: Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis. Blood 108: 3700-3706, 2006. (Pubitemid 44864547)
34. Baumann S, Fas SC, Giaisi M, et al: Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. Blood 111: 2354-2363, 2008. (Pubitemid 351451444)
35. Powlny AA and Singh SV: Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds. Cancer Lett 269: 305-314, 2008.
36. Murai M, Inoue T, Suzuki-Karasaki M, Ochiai T, Ra C, Nishida S, et al: Diallyl trisulfide sensitizes human melanoma cells to TRAIL-induced cell death by promoting endoplasmic reticulum-mediated apoptosis. Int J Oncol 41: 2029-2037, 2012.