Diallyl trisulfide sensitizes human melanoma cells to TRAIL-induced cell death by promoting endoplasmic reticulum-mediated apoptosis

International Journal of Oncology

Volumn 41, Issue 6, 2012, Pages 2029-2037

  Murai, Mayumi ^a,b   Inoue, Toshio ^a   Suzuki Karasaki, Miki ^b   Ochiai, Toyoko ^b   Ra, Chisei ^a   Nishida, Sigeru ^a   Suzuki Karasaki, Yoshihiro ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

Apoptosis; Diallyl trisulfide; Endoplasmic reticulum; Melanoma; Tumor necrosis factor related apoptosis inducing ligand

Indexed keywords

CASPASE 12; CASPASE 3; CASPASE 4; CASPASE 7; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DIALLYL TRISULFIDE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL DEATH; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; SENSITIZATION;

ALLYL COMPOUNDS; APOPTOSIS; CASPASE 12; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMANS; MELANOMA; MITOCHONDRIA; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SIGNAL TRANSDUCTION; SULFIDES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84869799967     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1656     Document Type: Article

References (35)

1. LeBlanc HN and Ashkenazi A: Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 10: 66-75, 2003. (Pubitemid 36511833)
2. Johnstone RW, Frew AJ and Smyth MJ: The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat Rev Cancer 8: 782-798, 2008.
3. Wang S: The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 27: 6207-6215, 2008.
4. Sayers TJ: Targeting the extrinsic apoptosis signaling pathway for cancer therapy. Cancer Immunol Immunother 60: 1173-1180, 2011.
5. Dyer MJ, MacFarlane M and Cohen GM: Barriers to effective TRAIL-targeted therapy of malignancy. J Clin Oncol 25: 4505-4506, 2007. (Pubitemid 350013865)
6. Das A, Banik NL and Ray SK: Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells. Cancer 110: 1083-1095, 2007. (Pubitemid 47312875)
7. Kim YA, Xiao D, Xiao H, et al: Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol Cancer Ther 6: 1599-1609, 2007. (Pubitemid 46954027)
8. Powlny AA and Singh SV: Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetablederived organosulfur compounds. Cancer Lett 269: 305-314, 2008.
9. Shankar S, Chen Q, Ganapathy S, Singh KP and Srivastava RK: Diallyl trisulfide increases the effectiveness of TRAIL and inhibits prostate cancer growth in an orthotropic model: molecular mechanisms. Mol Cancer Ther 7: 2328-2338, 2008.
10. + channels and endoplasmic reticulum stress. Int J Oncol 41: 465-475, 2012.
11. 2+ dependence of mast cell degranulation. J Leukoc Biol 79: 508-518, 2006.
12. Griffith TS, Rauch CT, Smolak PJ, et al: Functional analysis of TRAIL receptors using monoclonal antibodies. J Immunol 162: 2597-2605, 1999. (Pubitemid 29309279)
13. Kischkel FC, Lawrence DA, Tinel A, et al: Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 276: 46639-46646, 2001.
14. Pukac L, Kanakaraj P, Humphreys R, et al: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. Br J Cancer 92: 1430-1441, 2005. (Pubitemid 40705010)
15. Georgakis GV, Li Y, Humphreys R, et al: Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death. Br J Haematol 130: 501-510, 2005. (Pubitemid 43899752)
16. Boyce M and Yuan J: Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13: 363-373, 2006.
17. Breckenridge DG, Germain M, Mathai JP, et al: Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22: 8608-8618, 2003. (Pubitemid 38019196)
18. Groenendyk J and Michalak M: Endoplasmic reticulum quality control and apoptosis. Acta Biochim Pol 52: 381-395, 2005. (Pubitemid 41133773)
19. Chen LH, Jiang CC, Kiejda KA, et al: Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response. Carcinogenesis 28: 2328-2336, 2007. (Pubitemid 350111591)
20. Mahalingam D, Szegezdi E, Keane M, de Jong S and Samali A: TRAIL receptor signalling and modulation: are we on the right TRAIL? Cancer Treat Rev 35: 280-288, 2009.
21. Merino D, Lalaoui N, Morizot A, Schneider P, Solary E and Micheau O: Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 26: 7046-7055, 2006. (Pubitemid 44477684)
22. Busch C, Jacob C, Anwar A, et al: Diallylpolysulfides induce growth arrest and apoptosis. Int J Oncol 36: 743-749, 2010.
23. Lee BC, Park BH, Kim SY and Lee YJ: Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells. J Cell Biochem 112: 118-127, 2011.
24. Balch CM, Buzzaid AC, Soong SJ, et al: Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 19: 3635-3648, 2001. (Pubitemid 32786276)
25. Nakagawa T, Zhu H, Morishima N, et al: Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103, 2000. (Pubitemid 30038529)
26. Szegezdi E, Fitzgerald U and Samali A: Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann NY Acad Sci 1010: 186-194, 2003. (Pubitemid 38264973)
27. Rutkowski DT and Kaufman RJ: A trip to the ER: coping with stress. Trends Cell Biol 14: 20-28, 2004. (Pubitemid 38076857)
28. Hersey P and Zhang XD: Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma. Pigment Cell Melanoma Res 21: 358-367, 2008. (Pubitemid 351678087)
29. Liu H, Jiang CC, Lavis CJ, et al: 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2. Mol Cancer 8: 122, 2009.
30. Ferri KF and Kroemer G: Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-E263, 2001.
31. Rao RV, Castro-Obregon S, Frankowski H, et al: Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 277: 21836-21842, 2002. (Pubitemid 34952336)
32. Morishima N, Nakanishi K, Takenouchi H, Shibata T and Yasuhiko Y: An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294, 2002.
33. Xie Q, Khaoustov VI, Chung CC, et al: Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 36: 592-601, 2002. (Pubitemid 34977169)
34. Mandic A, Hansson J, Linder S and Shoshan MC: Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling. J Biol Chem 278: 9100-9106, 2003. (Pubitemid 36800390)
35. Shellman YG, Howe WR, Miller LA, et al: Hyperthermia induces endoplasmic reticulum-mediated apoptosis in melanoma and non-melanoma skin cancer cells. J Invest Dermatol 128: 949-956, 2008. (Pubitemid 351374306)