Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms

Annals of Human Genetics

Volumn 71, Issue 3, 2007, Pages 354-369

  Lao, O ^a,b   De Gruijter, J M ^a,b   Van Duijn, K ^a,b   Navarro, A ^c   Kayser, M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NETHERLANDS FORENSIC INSTITUTE   (Netherlands)

^c UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

EHH test; Genetic adaptation; Human pigmentation; Perlegen database; Positive selection; Skin color; SNP

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GENE PRODUCT; OCULOCUTANEOUS ALBINISM TYPE 2 PROTEIN; PROTEIN DCT; PROTEIN DRD2; PROTEIN KITLG; PROTEIN SLC45A2; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EVOLUTIONARY ADAPTATION; GENE LOCATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GEOGRAPHIC ORIGIN; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RACE DIFFERENCE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN COLOR; SKIN PIGMENTATION;

AFRICAN CONTINENTAL ANCESTRY GROUP; ASIAN CONTINENTAL ANCESTRY GROUP; DATABASES, GENETIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; GENETICS, POPULATION; GENOTYPE; HAPLOTYPES; HOMOZYGOTE; HUMANS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION (GENETICS); SKIN PIGMENTATION;

EID: 34247097012     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/j.1469-1809.2006.00341.x     Document Type: Article

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