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Volumn 8, Issue 11, 2013, Pages

Association of cytokine and toll-like receptor gene polymorphisms with severe malaria in three regions of cameroon

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; ALLELES; CAMEROON; CASE-CONTROL STUDIES; CYTOKINES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTORS; YOUNG ADULT;

EID: 84894265837     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081071     Document Type: Article
Times cited : (30)

References (65)
  • 1
    • 84874499711 scopus 로고    scopus 로고
    • Available: Accessed 2013 June 08
    • World Health Organisation (2012). World Malaria Report 2012. Available: http://www.who.int/malaria/publications/world-malaria-report-2012/report/en/ index.html. Accessed 2013 June 08
    • (2012) World Malaria Report 2012.
  • 2
    • 57649114759 scopus 로고    scopus 로고
    • A global network for investigating the genomic epidemiology of malaria
    • doi:10.1038/nature07632. PubMed: 19079050
    • Malaria GEN (2008) A global network for investigating the genomic epidemiology of malaria. Nature 456: 732-738. doi:10.1038/nature07632. PubMed: 19079050.
    • (2008) Nature , vol.456 , pp. 732-738
    • Malaria, G.E.N.1
  • 3
    • 1542720941 scopus 로고    scopus 로고
    • Innate immunity to malaria
    • doi:10.1038/nri1311. PubMed: 15039754
    • Stevenson MM, Riley EM (2004) Innate immunity to malaria. Nat Rev Immunol 4: 169-180. doi:10.1038/nri1311. PubMed: 15039754.
    • (2004) Nat Rev Immunol , vol.4 , pp. 169-180
    • Stevenson, M.M.1    Riley, E.M.2
  • 4
    • 29644447350 scopus 로고    scopus 로고
    • Heritability of malaria in Africa
    • doi:10.1371/journal.pmed.0020340. PubMed: 16259530
    • Mackinnon MJ, Mwangi TW, Snow RW, Marsh K, Williams TN (2005) Heritability of malaria in Africa. PLoS Med 2: e340. doi:10.1371/journal.pmed. 0020340. PubMed: 16259530.
    • (2005) PLoS Med , vol.2
    • Mackinnon, M.J.1    Mwangi, T.W.2    Snow, R.W.3    Marsh, K.4    Williams, T.N.5
  • 5
    • 45549097494 scopus 로고    scopus 로고
    • Immunity to malaria: More questions than answers
    • doi:10.1038/ni.f.205. PubMed: 18563083
    • Langhorne J, Ndungu FM, Sponaas AM, Marsh K (2008) Immunity to malaria: more questions than answers. Nat Immunol 9: 725-732. doi:10.1038/ni.f.205. PubMed: 18563083.
    • (2008) Nat Immunol , vol.9 , pp. 725-732
    • Langhorne, J.1    Ndungu, F.M.2    Sponaas, A.M.3    Marsh, K.4
  • 6
    • 0032722821 scopus 로고    scopus 로고
    • The cytokine balance in severe malarial anemia
    • doi:10.1086/315077. PubMed: 10515852
    • Kurtzhals JA, Akanmori BD, Goka BQ, Adabayeri V, Nkrumah FK et al. (1999) The cytokine balance in severe malarial anemia. J Infect Dis 180: 1753-1755. doi:10.1086/315077. PubMed: 10515852.
    • (1999) J Infect Dis , vol.180 , pp. 1753-1755
    • Kurtzhals, J.A.1    Akanmori, B.D.2    Goka, B.Q.3    Adabayeri, V.4    Nkrumah, F.K.5
  • 7
    • 0013564137 scopus 로고    scopus 로고
    • A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya
    • doi:10.1086/314548. PubMed: 9841855
    • Othoro C, Lal AA, Nahlen B, Koech D, Orago AS et al. (1999) A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya. J Infect Dis 179: 279-282. doi:10.1086/314548. PubMed: 9841855.
    • (1999) J Infect Dis , vol.179 , pp. 279-282
    • Othoro, C.1    Lal, A.A.2    Nahlen, B.3    Koech, D.4    Orago, A.S.5
  • 8
    • 57049122803 scopus 로고    scopus 로고
    • Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production
    • doi:10.1007/s00439-008-0578-5. PubMed: 18972133
    • Ouma C, Davenport GC, Were T, Otieno MF, Hittner JB et al. (2008) Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production. Hum Genet 124: 515-524. doi:10.1007/s00439-008-0578-5. PubMed: 18972133.
    • (2008) Hum Genet , vol.124 , pp. 515-524
    • Ouma, C.1    Davenport, G.C.2    Were, T.3    Otieno, M.F.4    Hittner, J.B.5
  • 9
    • 84894234184 scopus 로고    scopus 로고
    • Plasma Levels of Tumour Necrosis Factor-Alpha, Interleukin-10, Interleukin-12, Macrophage Inhibition Factor and Transforming Growth Factor-Beta in Children with Severe and Uncomplicated Falciparum Malaria
    • Achidi EA, Apinjoh TO, Yafi CN, Besingi R, Anchang JK, et al. (2013) Plasma Levels of Tumour Necrosis Factor-Alpha, Interleukin-10, Interleukin-12, Macrophage Inhibition Factor and Transforming Growth Factor-Beta in Children with Severe and Uncomplicated Falciparum Malaria. J Trop Dis 1: 103.
    • (2013) J Trop Dis , vol.1 , pp. 103
    • Achidi, E.A.1    Apinjoh, T.O.2    Yafi, C.N.3    Besingi, R.4    Anchang, J.K.5
  • 10
    • 7044231623 scopus 로고    scopus 로고
    • iNOS promoter variants and severe malaria in Ghanaian children
    • doi:10.1111/j.1365-3156.2004.01312.x
    • Cramer JP, Mockenhaupt FP, Ehrhardt S, Burkhardt J, Otchwemah RN et al. (2004) iNOS promoter variants and severe malaria in Ghanaian children. Trop Med Int Health 9: 1074-1080. doi:10.1111/j.1365-3156.2004.01312.x.
    • (2004) Trop Med Int Health , vol.9 , pp. 1074-1080
    • Cramer, J.P.1    Mockenhaupt, F.P.2    Ehrhardt, S.3    Burkhardt, J.4    Otchwemah, R.N.5
  • 11
    • 4344579064 scopus 로고    scopus 로고
    • Is there a future for TNF promoter polymorphisms?
    • doi:10.1038/sj.gene.6364055. PubMed: 14973548
    • Bayley JP, Ottenhoff TH, Verweij CL (2004) Is there a future for TNF promoter polymorphisms? Genes Immun 5: 315-329. doi:10.1038/sj.gene.6364055. PubMed: 14973548.
    • (2004) Genes Immun , vol.5 , pp. 315-329
    • Bayley, J.P.1    Ottenhoff, T.H.2    Verweij, C.L.3
  • 12
    • 33847748977 scopus 로고    scopus 로고
    • Immunogenetic control of antibody responsiveness in a malaria endemic area
    • doi:10.1016/j.humimm.2006.12.002. PubMed: 17349871
    • Carpenter D, Abushama H, Bereczky S, Färnert A, Rooth I et al. (2007) Immunogenetic control of antibody responsiveness in a malaria endemic area. Hum Immunol 68: 165-169. doi:10.1016/j.humimm.2006.12.002. PubMed: 17349871.
    • (2007) Hum Immunol , vol.68 , pp. 165-169
    • Carpenter, D.1    Abushama, H.2    Bereczky, S.3    Färnert, A.4    Rooth, I.5
  • 13
    • 0032993434 scopus 로고    scopus 로고
    • A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
    • doi:10.1038/9649. PubMed: 10369255
    • Knight JC, Udalova I, Hill AV, Greenwood BM, Peshu N et al. (1999) A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet 22: 145-150. doi:10.1038/9649. PubMed: 10369255.
    • (1999) Nat Genet , vol.22 , pp. 145-150
    • Knight, J.C.1    Udalova, I.2    Hill, A.V.3    Greenwood, B.M.4    Peshu, N.5
  • 14
    • 0032958707 scopus 로고    scopus 로고
    • Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles
    • doi:10.1086/314533. PubMed: 9841857
    • McGuire W, Knight JC, Hill AV, Allsopp CE, Greenwood BM et al. (1999) Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. J Infect Dis 179: 287-290. doi:10.1086/314533. PubMed: 9841857.
    • (1999) J Infect Dis , vol.179 , pp. 287-290
    • McGuire, W.1    Knight, J.C.2    Hill, A.V.3    Allsopp, C.E.4    Greenwood, B.M.5
  • 15
    • 58849141773 scopus 로고    scopus 로고
    • Tumor Necrosis Factor and Lymphotoxin-Alpha Polymorphisms and Severe Malaria in African Populations
    • doi:10.1086/596320. PubMed: 19281305
    • Clark TG, Diakite M, Auburn S, Campino S, Fry AE et al. (2009) Tumor Necrosis Factor and Lymphotoxin-Alpha Polymorphisms and Severe Malaria in African Populations. J Infect Dis 199: 569-575. doi:10.1086/596320. PubMed: 19281305.
    • (2009) J Infect Dis , vol.199 , pp. 569-575
    • Clark, T.G.1    Diakite, M.2    Auburn, S.3    Campino, S.4    Fry, A.E.5
  • 16
    • 58849135241 scopus 로고    scopus 로고
    • A genetic association study in The Gambia using tagging polymorphisms in the major histocompatibility complex (MHC) class III region implicates a HLA-B associated transcript 2 (BAT2) polymorphism in severe malaria susceptibility
    • doi:10.1007/s00439-008-0597-2. PubMed: 19039607
    • Diakite M, Clark TG, Auburn S, Campino SG, Fry AE et al. (2009) A genetic association study in The Gambia using tagging polymorphisms in the major histocompatibility complex (MHC) class III region implicates a HLA-B associated transcript 2 (BAT2) polymorphism in severe malaria susceptibility. Hum Genet 125: 105-109. doi:10.1007/s00439-008-0597-2. PubMed: 19039607.
    • (2009) Hum Genet , vol.125 , pp. 105-109
    • Diakite, M.1    Clark, T.G.2    Auburn, S.3    Campino, S.G.4    Fry, A.E.5
  • 17
    • 3242670468 scopus 로고    scopus 로고
    • Complex haplotypic structure of the central MHC region flanking TNF in a West African population
    • doi:10.1038/sj.gene.6364008. PubMed: 14551600
    • Ackerman HC, Ribas G, Jallow M, Mott R, Neville M et al. (2003) Complex haplotypic structure of the central MHC region flanking TNF in a West African population. Genes Immun 4: 476-486. doi:10.1038/sj.gene.6364008. PubMed: 14551600.
    • (2003) Genes Immun , vol.4 , pp. 476-486
    • Ackerman, H.C.1    Ribas, G.2    Jallow, M.3    Mott, R.4    Neville, M.5
  • 18
    • 22544441601 scopus 로고    scopus 로고
    • How malaria has affected the human genome and what human genetics can teach us about malaria
    • doi:10.1086/432519. PubMed: 16001361
    • Kwiatkowski DP (2005) How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 77: 171-192. doi:10.1086/432519. PubMed: 16001361.
    • (2005) Am J Hum Genet , vol.77 , pp. 171-192
    • Kwiatkowski, D.P.1
  • 19
    • 0031017238 scopus 로고    scopus 로고
    • An investigation of polymorphism in the interleukin-10 gene promoter
    • doi:10.1111/j.1365-2370.1997.tb00001.x
    • Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ et al. (1997) An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 24: 1-8. doi:10.1111/j.1365-2370.1997.tb00001.x.
    • (1997) Eur J Immunogenet , vol.24 , pp. 1-8
    • Turner, D.M.1    Williams, D.M.2    Sankaran, D.3    Lazarus, M.4    Sinnott, P.J.5
  • 20
    • 0035869289 scopus 로고    scopus 로고
    • Novel single nucleotide polymorphisms in the distal IL-10 promoter affect IL-10 production and enhance the risk of systemic lupus erythematosus
    • Gibson AW, Edberg JC, Wu J, Westendorp RG, Huizinga TW et al. (2001) Novel single nucleotide polymorphisms in the distal IL-10 promoter affect IL-10 production and enhance the risk of systemic lupus erythematosus. J Immunol 66: 3915-3922.
    • (2001) J Immunol , vol.66 , pp. 3915-3922
    • Gibson, A.W.1    Edberg, J.C.2    Wu, J.3    Westendorp, R.G.4    Huizinga, T.W.5
  • 21
    • 22544458241 scopus 로고    scopus 로고
    • Analysis of IL10 haplotypic associations with severe malaria
    • doi:10.1038/sj.gene.6364227. PubMed: 15933743
    • Wilson JN, Rockett K, Jallow M, Pinder M, Sisay-Joof F et al. (2005) Analysis of IL10 haplotypic associations with severe malaria. Genes Immun 6: 462-466. doi:10.1038/sj.gene.6364227. PubMed: 15933743.
    • (2005) Genes Immun , vol.6 , pp. 462-466
    • Wilson, J.N.1    Rockett, K.2    Jallow, M.3    Pinder, M.4    Sisay-Joof, F.5
  • 23
    • 21344433481 scopus 로고    scopus 로고
    • Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region
    • doi:10.1038/sj.gene.6364214. PubMed: 15858598
    • Koch O, Rockett K, Jallow M, Pinder M, Sisay-Joof F et al. (2005) Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region. Genes Immun 6: 312-318. doi:10.1038/sj.gene.6364214. PubMed: 15858598.
    • (2005) Genes Immun , vol.6 , pp. 312-318
    • Koch, O.1    Rockett, K.2    Jallow, M.3    Pinder, M.4    Sisay-Joof, F.5
  • 24
    • 1342346046 scopus 로고    scopus 로고
    • Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case-control study
    • doi:10.1038/sj.ejhg.5201084. PubMed: 14673470
    • Walley AJ, Aucan C, Kwiatkowski D, Hill AV (2004) Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case-control study. Eur J Hum Genet 12: 132-138. doi:10.1038/sj.ejhg.5201084. PubMed: 14673470.
    • (2004) Eur J Hum Genet , vol.12 , pp. 132-138
    • Walley, A.J.1    Aucan, C.2    Kwiatkowski, D.3    Hill, A.V.4
  • 25
    • 14844337835 scopus 로고    scopus 로고
    • Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: Cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity
    • PubMed: 15623512
    • Krishnegowda G, Hajjar AM, Zhu J, Douglass EJ, Uematsu S et al. (2005) Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity. J Biol Chem 280: 8606-8616. PubMed: 15623512.
    • (2005) J Biol Chem , vol.280 , pp. 8606-8616
    • Krishnegowda, G.1    Hajjar, A.M.2    Zhu, J.3    Douglass, E.J.4    Uematsu, S.5
  • 26
    • 30444459750 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
    • doi:10.1073/pnas.0506803102. PubMed: 1737335516371473
    • Mockenhaupt FP, Cramer JP, Hamann L, Stegemann MS, Eckert J et al. (2006a) Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sciences U-S-A, 103: 177-182. doi:10.1073/pnas.0506803102. PubMed: 1737335516371473.
    • (2006) Proc Natl Acad Sciences U-S-A , vol.103 , pp. 177-182
    • Mockenhaupt, F.P.1    Cramer, J.P.2    Hamann, L.3    Stegemann, M.S.4    Eckert, J.5
  • 27
    • 33746162770 scopus 로고    scopus 로고
    • Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy
    • doi:10.1086/505152. PubMed: 16779724
    • Mockenhaupt FP, Hamann L, von Gaertner C, Bedu-Addo G, von Kleinsorgen C et al. (2006b) Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy. J Infect Dis 194: 184-188. doi:10.1086/505152. PubMed: 16779724.
    • (2006) J Infect Dis , vol.194 , pp. 184-188
    • Mockenhaupt, F.P.1    Hamann, L.2    Von Gaertner, C.3    Bedu-Addo, G.4    Von Kleinsorgen, C.5
  • 28
    • 11144358459 scopus 로고    scopus 로고
    • Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway
    • PubMed: 15067072
    • Pichyangkul S, Yongvanitchit K, Kum-arb U, Hemmi H, Akira S et al. (2004) Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J Immunol 172: 4926-4933. PubMed: 15067072.
    • (2004) J Immunol , vol.172 , pp. 4926-4933
    • Pichyangkul, S.1    Yongvanitchit, K.2    Kum-arb, U.3    Hemmi, H.4    Akira, S.5
  • 29
    • 19944430901 scopus 로고    scopus 로고
    • Toll-like receptor 9 mediates innate immune activation by the malaria pigment haemozoin
    • doi:10.1084/jem.20041836. PubMed: 15630134
    • Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S et al. (2005) Toll-like receptor 9 mediates innate immune activation by the malaria pigment haemozoin. J Exp Med 201: 19-25. doi:10.1084/jem.20041836. PubMed: 15630134.
    • (2005) J Exp Med , vol.201 , pp. 19-25
    • Coban, C.1    Ishii, K.J.2    Kawai, T.3    Hemmi, H.4    Sato, S.5
  • 30
    • 42149134289 scopus 로고    scopus 로고
    • Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells
    • PubMed: 18250459
    • Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L et al. (2008) Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells. J Immunol 180: 2496-2503. PubMed: 18250459.
    • (2008) J Immunol , vol.180 , pp. 2496-2503
    • Hisaeda, H.1    Tetsutani, K.2    Imai, T.3    Moriya, C.4    Tu, L.5
  • 31
    • 15544369643 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease
    • doi:10.1016/S1473-3099(05)70023-2. PubMed: 15766650
    • Schröder NWJ, Schumann RR (2005) Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease. Lancet Infect Dis 5: 156-164. doi:10.1016/S1473-3099(05)70023-2. PubMed: 15766650.
    • (2005) Lancet Infect Dis , vol.5 , pp. 156-164
    • Schröder, N.W.J.1    Schumann, R.R.2
  • 32
    • 0034084438 scopus 로고    scopus 로고
    • TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
    • doi:10.1038/76048. PubMed: 10835634
    • Arbour NC, Lorenz E, Schutte BC, Zabner J, Kline JN et al. (2000) TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 25: 187-191. doi:10.1038/76048. PubMed: 10835634.
    • (2000) Nat Genet , vol.25 , pp. 187-191
    • Arbour, N.C.1    Lorenz, E.2    Schutte, B.C.3    Zabner, J.4    Kline, J.N.5
  • 33
    • 5444254408 scopus 로고    scopus 로고
    • Toll-like receptors in the pathogenesis of human disease
    • doi:10.1038/ni1116. PubMed: 15454920
    • Cook DN, Pisetsky DS, Schwartz DA (2004) Toll-like receptors in the pathogenesis of human disease. Nat Immunol 5: 975-979. doi:10.1038/ni1116. PubMed: 15454920.
    • (2004) Nat Immunol , vol.5 , pp. 975-979
    • Cook, D.N.1    Pisetsky, D.S.2    Schwartz, D.A.3
  • 34
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
    • doi:10.1001/archinte.162.9.1028. PubMed: 11996613
    • Lorenz E, Mira JP, Frees KL, Schwartz DA (2002) Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 162: 1028-1032. doi:10.1001/archinte.162.9.1028. PubMed: 11996613.
    • (2002) Arch Intern Med , vol.162 , pp. 1028-1032
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3    Schwartz, D.A.4
  • 35
    • 0035450762 scopus 로고    scopus 로고
    • A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease
    • doi:10.1086/322798. PubMed: 11494169
    • Read RC, Pullin J, Gregory S, Borrow R, Kaczmarski EB et al. (2001) A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease. J Infect Dis 184: 640-642. doi:10.1086/322798. PubMed: 11494169.
    • (2001) J Infect Dis , vol.184 , pp. 640-642
    • Read, R.C.1    Pullin, J.2    Gregory, S.3    Borrow, R.4    Kaczmarski, E.B.5
  • 36
    • 0037947560 scopus 로고    scopus 로고
    • Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
    • doi:10.1073/pnas.1031605100. PubMed: 12730365
    • Smirnova I, Mann N, Dols A, Derkx HH, Hibberd ML et al. (2003) Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility. Proc Natl Acad Sci U S A 100: 6075-6080. doi:10.1073/pnas.1031605100. PubMed: 12730365.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6075-6080
    • Smirnova, I.1    Mann, N.2    Dols, A.3    Derkx, H.H.4    Hibberd, M.L.5
  • 37
    • 4444223628 scopus 로고    scopus 로고
    • Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women
    • doi:10.1016/j.ejogrb.2004.02.010. PubMed: 15358455
    • Genc MR, Vardhana S, Delaney ML, Onderdonk A, Tuomala R et al. (2004) Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women. Eur J Obstet Gynecol Reprod Biol 116: 152-156. doi:10.1016/j.ejogrb.2004.02.010. PubMed: 15358455.
    • (2004) Eur J Obstet Gynecol Reprod Biol , vol.116 , pp. 152-156
    • Genc, M.R.1    Vardhana, S.2    Delaney, M.L.3    Onderdonk, A.4    Tuomala, R.5
  • 38
    • 0037289001 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): Frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. Ethnic groups and exploratory case-control disease association studies
    • doi:10.1016/S0888-7543(02)00022-8. PubMed: 12573264.
    • Lazarus R, Klimecki WT, Raby BA, Vercelli D, Palmer LJ et al. (2003) Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 81: 85-91. doi:10.1016/S0888-7543(02)00022-8. PubMed: 12573264.
    • (2003) Genomics , vol.81 , pp. 85-91
    • Lazarus, R.1    Klimecki, W.T.2    Raby, B.A.3    Vercelli, D.4    Palmer, L.J.5
  • 39
    • 3242732415 scopus 로고    scopus 로고
    • Crohn's disease is associated with a toll-like receptor-9 polymorphism
    • doi:10.1053/j.gastro.2004.05.051. PubMed: 15236225
    • Török HP, Glas J, Tonenchi L, Bruennler G, Folwaczny M et al. (2004) Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology 127: 365-366. doi:10.1053/j.gastro.2004.05.051. PubMed: 15236225.
    • (2004) Gastroenterology , vol.127 , pp. 365-366
    • Török, H.P.1    Glas, J.2    Tonenchi, L.3    Bruennler, G.4    Folwaczny, M.5
  • 40
    • 50949083504 scopus 로고    scopus 로고
    • Variants in the Toll-Like Receptor Signaling Pathway and Clinical Outcomes of Malaria
    • doi:10.1086/590440. PubMed: 18662133
    • Leoratti FM, Farias L, Alves FP, Suarez-Mútis MC, Coura JR et al. (2008) Variants in the Toll-Like Receptor Signaling Pathway and Clinical Outcomes of Malaria. J Infect Dis 198: 772-780. doi:10.1086/590440. PubMed: 18662133.
    • (2008) J Infect Dis , vol.198 , pp. 772-780
    • Leoratti, F.M.1    Farias, L.2    Alves, F.P.3    Suarez-Mútis, M.C.4    Coura, J.R.5
  • 41
    • 63149134878 scopus 로고    scopus 로고
    • TLR9 polymorphisms in African populations: No association with severe malaria, but evidence of cis-variants acting on gene expression
    • doi:10.1186/1475-2875-8-44. PubMed: 19284650
    • Campino S, Forton J, Auburn S, Fry A, Diakite M et al. (2009) TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression. Malar J 8: 44. doi:10.1186/1475-2875-8-44. PubMed: 19284650.
    • (2009) Malar J , vol.8 , pp. 44
    • Campino, S.1    Forton, J.2    Auburn, S.3    Fry, A.4    Diakite, M.5
  • 42
    • 67349278465 scopus 로고    scopus 로고
    • Genome-wide and fine-resolution association analysis of malaria in West Africa
    • doi:10.1038/ng.388. PubMed: 19465909
    • Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P et al. (2009) Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet 41: 657-665. doi:10.1038/ng.388. PubMed: 19465909.
    • (2009) Nat Genet , vol.41 , pp. 657-665
    • Jallow, M.1    Teo, Y.Y.2    Small, K.S.3    Rockett, K.A.4    Deloukas, P.5
  • 43
    • 84866020850 scopus 로고    scopus 로고
    • Candidate Polymorphisms and Severe Malaria in a Malian. Population
    • doi:10.1371/journal.pone.0043987
    • Toure O, Konate S, Sissoko S, Niangaly A, Barry A et al. (2012) Candidate Polymorphisms and Severe Malaria in a Malian. Population - PLOS ONE 7: e43987. doi:10.1371/journal.pone.0043987.
    • (2012) PLOS ONE , vol.7
    • Toure, O.1    Konate, S.2    Sissoko, S.3    Niangaly, A.4    Barry, A.5
  • 44
    • 84868092905 scopus 로고    scopus 로고
    • Candidate Human Genetic Polymorphisms and Severe Malaria in a Tanzanian
    • doi:10.1371/journal.pone.0047463
    • Manjurano A, Clark TG, Nadjm B, Mtove G, Wangai H et al. (2012) Candidate Human Genetic Polymorphisms and Severe Malaria in a Tanzanian. Population - PLOS ONE 7: e47463. doi:10.1371/journal.pone.0047463.
    • (2012) Population - PLOS ONE , vol.7
    • Manjurano, A.1    Clark, T.G.2    Nadjm, B.3    Mtove, G.4    Wangai, H.5
  • 45
    • 44449127286 scopus 로고    scopus 로고
    • Febrile status, malarial parasitaemia and gastro-intestinal helminthiases in school children resident at different altitudes, in south-western Cameroon
    • doi:10.1179/136485908X252287. PubMed: 18318932
    • Achidi EA, Apinjoh TO, Mbunwe E, Besingi R, Yafi C et al. (2008) Febrile status, malarial parasitaemia and gastro-intestinal helminthiases in school children resident at different altitudes, in south-western Cameroon. Ann Trop Med Parasitol 102: 103-118. doi:10.1179/136485908X252287. PubMed: 18318932.
    • (2008) Ann Trop Med Parasitol , vol.102 , pp. 103-118
    • Achidi, E.A.1    Apinjoh, T.O.2    Mbunwe, E.3    Besingi, R.4    Yafi, C.5
  • 46
    • 84862531479 scopus 로고    scopus 로고
    • Severe and uncomplicated falciparum malaria in children from three regions and three ethnic groups in Cameroon: Prospective study
    • doi:10.1186/1475-2875-11-215. PubMed: 22727184
    • Achidi EA, Apinjoh TO, Anchang-Kimbi JK, Mugri RN, Ngwai AN et al. (2012) Severe and uncomplicated falciparum malaria in children from three regions and three ethnic groups in Cameroon: prospective study. Malar J 11: 215. doi:10.1186/1475-2875-11-215. PubMed: 22727184.
    • (2012) Malar J , vol.11 , pp. 215
    • Achidi, E.A.1    Apinjoh, T.O.2    Anchang-Kimbi, J.K.3    Mugri, R.N.4    Ngwai, A.N.5
  • 47
    • 0034068284 scopus 로고    scopus 로고
    • Severe falciparum malaria
    • World Health Organisation doi:10.1016/S0035-9203(00)90413-9. PubMed: 11103309
    • World Health Organisation (2000) Severe falciparum malaria. Trans R Soc Trop Med Hyg 94: S1-S90. doi:10.1016/S0035-9203(00)90413-9. PubMed: 11103309.
    • (2000) Trans R Soc Trop Med Hyg , vol.94
  • 48
    • 0026047420 scopus 로고
    • Plasmodium falciparum reinfection in children from a holoendemic area in relation to seroreactivities against oligopeptides from different malarial antigens
    • PubMed: 1718179
    • Rooth I, Perlmann H, Bjorkman A (1991) Plasmodium falciparum reinfection in children from a holoendemic area in relation to seroreactivities against oligopeptides from different malarial antigens. Am J Trop Med Hyg 45: 309-318. PubMed: 1718179.
    • (1991) Am J Trop Med Hyg , vol.45 , pp. 309-318
    • Rooth, I.1    Perlmann, H.2    Bjorkman, A.3
  • 49
    • 0026755807 scopus 로고
    • Whole genome amplification from a single cell: Implications for genetic analysis
    • doi:10.1073/pnas.89.13.5847. PubMed: 1631067
    • Zhang L, Cui X, Schmitt K, Hubert R, Navidi W et al. (1992) Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci U S A 89: 5847-5851. doi:10.1073/pnas.89.13.5847. PubMed: 1631067.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5847-5851
    • Zhang, L.1    Cui, X.2    Schmitt, K.3    Hubert, R.4    Navidi, W.5
  • 50
    • 0031734601 scopus 로고    scopus 로고
    • High level multiplex genotyping by MALDI-TOF mass spectrometry
    • doi:10.1038/4328. PubMed: 9853617
    • Ross P, Hall L, Smirnov I, Haff L (1998) High level multiplex genotyping by MALDI-TOF mass spectrometry. Nat Biotechnol 16: 1347-1351. doi:10.1038/4328. PubMed: 9853617.
    • (1998) Nat Biotechnol , vol.16 , pp. 1347-1351
    • Ross, P.1    Hall, L.2    Smirnov, I.3    Haff, L.4
  • 51
    • 34447647653 scopus 로고    scopus 로고
    • On the usage of HWE for identifying genotyping errors
    • doi:10.1111/j.1469-1809.2007.00356.x. PubMed: 17388941
    • Teo YY, Fry AE, Clark TG, Tai ES, Seielstad M (2007) On the usage of HWE for identifying genotyping errors. Ann Hum Genet 71: 701-704. doi:10.1111/j.1469-1809.2007.00356.x. PubMed: 17388941.
    • (2007) Ann Hum Genet , vol.71 , pp. 701-704
    • Teo, Y.Y.1    Fry, A.E.2    Clark, T.G.3    Tai, E.S.4    Seielstad, M.5
  • 52
    • 0032231356 scopus 로고    scopus 로고
    • Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33
    • doi:10.1086/301967. PubMed: 9683598
    • Rihet P, Traoré Y, Abel L, Aucan C, Traoré-Leroux T et al. (1998) Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33. Am J Hum Genet 63: 498-505. doi:10.1086/301967. PubMed: 9683598.
    • (1998) Am J Hum Genet , vol.63 , pp. 498-505
    • Rihet, P.1    Traoré, Y.2    Abel, L.3    Aucan, C.4    Traoré-Leroux, T.5
  • 53
    • 4644285874 scopus 로고    scopus 로고
    • Allelic polymorphisms in the repeat and promoter regions of the interleukin-4 gene and malaria severity in Ghanaian children
    • doi:10.1111/j.1365-2249.2004.02590.x PubMed: 15373917
    • Gyan BA, Goka B, Cvetkovic JT, Kurtzhals JL, Adabayeri V et al. (2004) Allelic polymorphisms in the repeat and promoter regions of the interleukin-4 gene and malaria severity in Ghanaian children. Clin Exp Immunol 138: 145-150. doi:10.1111/j.1365-2249.2004.02590.x. PubMed: 15373917.
    • (2004) Clin Exp Immunol , vol.138 , pp. 145-150
    • Gyan, B.A.1    Goka, B.2    Cvetkovic, J.T.3    Kurtzhals, J.L.4    Adabayeri, V.5
  • 54
    • 0033188305 scopus 로고    scopus 로고
    • An IL-13 promoter polymorphism associated with increased risk of allergic asthma
    • doi:10.1038/sj.gene.6363630. PubMed: 11197307
    • van der Pouw Kraan TC, van Veen A, Boeije LC, van Tuyl SA, de Groot ER et al. (1999) An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immun 1: 61-65. doi:10.1038/sj.gene.6363630. PubMed: 11197307.
    • (1999) Genes Immun , vol.1 , pp. 61-65
    • Van Der, P.1    Kraan, T.C.2    Van Veen, A.3    Boeije, L.C.4    Van Tuyl, S.A.5    De Groot, E.R.6
  • 55
    • 2442434976 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism
    • doi:10.1038/sj.gene.6363896. PubMed: 12424628
    • van der Pouw Kraan TC, Küçükaycan M, Bakker AM, Baggen JM, van der Zee JS et al. (2002) Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism. Genes Immun 3: 436-439. doi:10.1038/sj.gene.6363896. PubMed: 12424628.
    • (2002) Genes Immun , vol.3 , pp. 436-439
    • Van Der, P.1    Kraan, T.C.2    Küçükaycan, M.3    Bakker, A.M.4    Baggen, J.M.5    Van Der Zee, J.S.6
  • 56
    • 3242745930 scopus 로고    scopus 로고
    • A single-nucleotide substitution from C to T at position-1055 in the IL-13 promoter is associated with protection from severe malaria in Thailand
    • doi:10.1038/sj.gene.6364010. PubMed: 14551608
    • Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Looareesuwan S et al. (2003) A single-nucleotide substitution from C to T at position-1055 in the IL-13 promoter is associated with protection from severe malaria in Thailand. Genes Immun 4: 528-531. doi:10.1038/sj.gene.6364010. PubMed: 14551608.
    • (2003) Genes Immun , vol.4 , pp. 528-531
    • Ohashi, J.1    Naka, I.2    Patarapotikul, J.3    Hananantachai, H.4    Looareesuwan, S.5
  • 57
    • 0031017238 scopus 로고    scopus 로고
    • An investigation of polymorphism in the interleukin-10 gene promoter
    • doi:10.1111/j.1365-2370.1997.tb00001.x. PubMed: 9043871
    • Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV (1997) An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 24: 1-8. doi:10.1111/j.1365-2370.1997.tb00001.x. PubMed: 9043871.
    • (1997) Eur J Immunogenet , vol.24 , pp. 1-8
    • Turner, D.M.1    Williams, D.M.2    Sankaran, D.3    Lazarus, M.4    Sinnott, P.J.5    Hutchinson, I.V.6
  • 58
    • 4143095716 scopus 로고    scopus 로고
    • IL-22 increases the innate immunity of tissues
    • doi:10.1016/j.immuni.2004.07.007. PubMed: 15308104
    • Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K et al. (2004) IL-22 increases the innate immunity of tissues. Immunity 21: 241-254. doi:10.1016/j.immuni.2004.07.007. PubMed: 15308104.
    • (2004) Immunity , vol.21 , pp. 241-254
    • Wolk, K.1    Kunz, S.2    Witte, E.3    Friedrich, M.4    Asadullah, K.5
  • 59
    • 34248531947 scopus 로고    scopus 로고
    • Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers
    • doi:10.1097/QAD.0b013e3280ef6ae1. PubMed: 17502719
    • Ball TB, Ji H, Kimani J, McLaren P, Marlin C et al. (2007) Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers. AIDS 21: 1091-1101. doi:10.1097/QAD. 0b013e3280ef6ae1. PubMed: 17502719.
    • (2007) AIDS , vol.21 , pp. 1091-1101
    • Ball, T.B.1    Ji, H.2    Kimani, J.3    McLaren, P.4    Marlin, C.5
  • 60
    • 40449141354 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection
    • doi:10.1038/sj.gene.6364456. PubMed: 18200030
    • Mangano VD, Luoni G, Rockett KA, Sirima BS, Konaté A et al. (2008) Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection. Genes Immun 9: 122-129. doi:10.1038/sj.gene. 6364456. PubMed: 18200030.
    • (2008) Genes Immun , vol.9 , pp. 122-129
    • Mangano, V.D.1    Luoni, G.2    Rockett, K.A.3    Sirima, B.S.4    Konaté, A.5
  • 61
    • 58449114885 scopus 로고    scopus 로고
    • Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations
    • doi:10.1371/journal.pone.0004206. PubMed: 19145247
    • Mangano VD, Clark TG, Auburn S, Campino S, Diakite M et al. (2009) Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations. PLOS ONE 4: e4206. doi:10.1371/journal.pone.0004206. PubMed: 19145247.
    • (2009) PLOS ONE , vol.4
    • Mangano, V.D.1    Clark, T.G.2    Auburn, S.3    Campino, S.4    Diakite, M.5
  • 62
    • 38449113583 scopus 로고    scopus 로고
    • Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host
    • doi:10.1086/522865. PubMed: 18008236
    • Griffith JW, O'Connor C, Bernard K, Town T, Goldstein DR et al. (2007) Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. J Infect Dis 196: 1553-1564. doi:10.1086/522865. PubMed: 18008236.
    • (2007) J Infect Dis , vol.196 , pp. 1553-1564
    • Griffith, J.W.1    O'Connor, C.2    Bernard, K.3    Town, T.4    Goldstein, D.R.5
  • 63
    • 34548481970 scopus 로고    scopus 로고
    • Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas
    • doi:10.1038/sj.onc.1210424. PubMed: 17420726
    • Zisman-Rozen S, Fink D, Ben-Izhak O, Fuchs Y, Brodski A et al. (2007) Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas. Oncogene 26: 6093-6098. doi:10.1038/sj.onc.1210424. PubMed: 17420726.
    • (2007) Oncogene , vol.26 , pp. 6093-6098
    • Zisman-Rozen, S.1    Fink, D.2    Ben-Izhak, O.3    Fuchs, Y.4    Brodski, A.5
  • 64
    • 38049009931 scopus 로고    scopus 로고
    • Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children
    • doi:10.1186/1475-2875-6-147. PubMed: 17997848
    • Armah HB, Wilson NO, Sarfo BY, Powell MD, Bond VC et al. (2007) Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J 6: 147. doi:10.1186/1475-2875-6-147. PubMed: 17997848.
    • (2007) Malar J , vol.6 , pp. 147
    • Armah, H.B.1    Wilson, N.O.2    Sarfo, B.Y.3    Powell, M.D.4    Bond, V.C.5
  • 65
    • 44449105631 scopus 로고    scopus 로고
    • Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
    • doi:10.1186/1475-2875-7-83. PubMed: 18489763
    • Jain V, Armah HB, Tongren JE, Ned RM, Wilson NO et al. (2008) Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J 7: 83. doi:10.1186/1475-2875-7-83. PubMed: 18489763.
    • (2008) Malar J , vol.7 , pp. 83
    • Jain, V.1    Armah, H.B.2    Tongren, J.E.3    Ned, R.M.4    Wilson, N.O.5


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