RNA suppression of ERK2 leads to collapse of mitochondrial membrane potential with acute oxidative stress in human lens epithelial cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 294, Issue 3, 2008, Pages

  Flynn, James M ^a   Lannigan, Deborah A ^b   Clark, David E ^b   Garner, Margaret H ^a   Cammarata, Patrick R ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

17 estradiol; Mitochondrial membrane potential; Mitochondrial permeability transition

Indexed keywords

ESTRADIOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXIDE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN BAD; PROTEIN SERINE THREONINE KINASE; RNA; S6 KINASE; SERINE; SL 0101; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LENS EPITHELIUM; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

BCL-ASSOCIATED DEATH PROTEIN; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EPITHELIAL CELLS; ESTRADIOL; HUMANS; LENS, CRYSTALLINE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; OXIDATIVE STRESS; PHOSPHORYLATION; RNA, SMALL INTERFERING; SERINE;

EID: 40449098332     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00705.2007     Document Type: Article

References (49)