-
1
-
-
0023058242
-
Human papilloma virus and cervical cancer
-
doi:10.1126/science.3003916. PubMed: 3003916
-
Marx JL (1986) Human papilloma virus and cervical cancer. Science 231: 920. doi:10.1126/science.3003916. PubMed: 3003916.
-
(1986)
Science
, vol.231
, pp. 920
-
-
Marx, J.L.1
-
2
-
-
84873054456
-
Human Papilloma Virus (HPV) E7-Mediated Attenuation of Retinoblastoma (Rb) Induces hPygopus2 Expression via Elf-1 in Cervical
-
doi:10.1158/1541-7786.MCR-12-0510
-
Tzenov YR, Andrews PG, Voisey K, Popadiuk P, Xiong J et al. (2013) Human Papilloma Virus (HPV) E7-Mediated Attenuation of Retinoblastoma (Rb) Induces hPygopus2 Expression via Elf-1 in Cervical. Cancer - Mol Cancer Res 11: 19-30. doi:10.1158/1541-7786.MCR-12-0510.
-
(2013)
Cancer - Mol Cancer Res
, vol.11
, pp. 19-30
-
-
Tzenov, Y.R.1
Andrews, P.G.2
Voisey, K.3
Popadiuk, P.4
Xiong, J.5
-
3
-
-
84859224604
-
Correlation of histopathologic/cytologic follow-up findings with vaginal ASC-US and ASC-H Papanicolaou test and HPV test results
-
doi:10.1309/AJCP9TO1OMXLDDPI. PubMed: 22338056
-
Bansal M, Li Z, Zhao C (2012) Correlation of histopathologic/cytologic follow-up findings with vaginal ASC-US and ASC-H Papanicolaou test and HPV test results. Am J Clin Pathol 137: 437-443. doi:10.1309/AJCP9TO1OMXLDDPI. PubMed: 22338056.
-
(2012)
Am J Clin Pathol
, vol.137
, pp. 437-443
-
-
Bansal, M.1
Li, Z.2
Zhao, C.3
-
4
-
-
78650657593
-
The prevention of cervical cancer in Africa
-
Lond Engl
-
Fiander AN (2011) The prevention of cervical cancer in Africa. Womens Health (Lond Engl) 7: 121-132.
-
(2011)
Womens Health
, vol.7
, pp. 121-132
-
-
Fiander, A.N.1
-
6
-
-
0028771996
-
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration
-
doi:10.1126/science.264.5161.891-d. PubMed: 8178144
-
Suzuki CK, Suda K, Wang N, Schatz G (1994) Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science 264: 891. doi:10.1126/science.264.5161.891-d. PubMed: 8178144.
-
(1994)
Science
, vol.264
, pp. 891
-
-
Suzuki, C.K.1
Suda, K.2
Wang, N.3
Schatz, G.4
-
7
-
-
0345791524
-
Proteomic analysis of rat liver peroxisome. Presence of peroxisome-specific isozyme of Lon protease
-
DOI 10.1074/jbc.M305623200
-
Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T et al. (2004) Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. J Biol Chem 279: 421-428. PubMed: 14561759. (Pubitemid 38044842)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.1
, pp. 421-428
-
-
Kikuchi, M.1
Hatano, N.2
Yokota, S.3
Shimozawa, N.4
Imanaka, T.5
Taniguchi, H.6
-
8
-
-
33645728835
-
Oligomeric structure of the ATP-dependent protease la (Lon) of Escherichia coli
-
PubMed: 16511355
-
Park SC, Jia B, Yang JK, Van DL, Shao YG et al. (2006) Oligomeric structure of the ATP-dependent protease La (Lon) of Escherichia coli. Mol Cells 21: 129-134. PubMed: 16511355.
-
(2006)
Mol Cells
, vol.21
, pp. 129-134
-
-
Park, S.C.1
Jia, B.2
Yang, J.K.3
Van, D.L.4
Shao, Y.G.5
-
9
-
-
34548446023
-
Turnover of mitochondrial Steroidogenic Acute Regulatory (StAR) protein by lon protease: The unexpected effect of proteasome inhibitors
-
DOI 10.1210/me.2005-0458
-
Granot Z, Kobiler O, Melamed-Book N, Eimerl S, Bahat A et al. (2007) Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors. Mol Endocrinol 21: 2164-2177. doi:10.1210/me.2005-0458. PubMed: 17579211. (Pubitemid 47351216)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.9
, pp. 2164-2177
-
-
Granot, Z.1
Kobiler, O.2
Melamed-Book, N.3
Eimerl, S.4
Bahat, A.5
Lu, B.6
Braun, S.7
Maurizi, M.R.8
Suzuki, C.K.9
Oppenheim, A.B.10
Orly, J.11
-
10
-
-
33947724515
-
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
-
DOI 10.1016/j.cell.2007.01.047, PII S0092867407003078
-
Fukuda R, Zhang H, Kim JW, Shimoda L, Dang CV et al. (2007) HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 129: 111-122. doi:10.1016/j.cell.2007.01.047. PubMed: 17418790. (Pubitemid 46507584)
-
(2007)
Cell
, vol.129
, Issue.1
, pp. 111-122
-
-
Fukuda, R.1
Zhang, H.2
Kim, J.-w.3
Shimoda, L.4
Dang, C.V.5
Semenza, G.L.6
-
11
-
-
84875679578
-
Engineering fluorescent protein substrates for the AAA+ Lon protease
-
PubMed: 23359718
-
Wohlever ML, Nager AR, Baker TA, Sauer RT (2013) Engineering fluorescent protein substrates for the AAA+ Lon protease. Protein Eng Des Sel, 26: 299-305. PubMed: 23359718.
-
(2013)
Protein Eng des Sel
, vol.26
, pp. 299-305
-
-
Wohlever, M.L.1
Nager, A.R.2
Baker, T.A.3
Sauer, R.T.4
-
12
-
-
84855225838
-
Multitasking in the mitochondrion by the ATP-dependent Lon protease
-
doi:10.1016/j.bbamcr.2011.11.003. PubMed: 22119779
-
Venkatesh S, Lee J, Singh K, Lee I, Suzuki CK (2012) Multitasking in the mitochondrion by the ATP-dependent Lon protease. Biochim Biophys Acta 1823: 56-66. doi:10.1016/j.bbamcr.2011.11.003. PubMed: 22119779.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 56-66
-
-
Venkatesh, S.1
Lee, J.2
Singh, K.3
Lee, I.4
Suzuki, C.K.5
-
13
-
-
78650046357
-
Functional characterization of the promoter of the human Lon protease gene
-
doi:10.1016/j.mito.2010.09.010. PubMed: 20933102
-
Pinti M, Gibellini L, De Biasi S, Nasi M, Roat E et al. (2011) Functional characterization of the promoter of the human Lon protease gene. Mitochondrion 11: 200-206. doi:10.1016/j.mito.2010.09.010. PubMed: 20933102.
-
(2011)
Mitochondrion
, vol.11
, pp. 200-206
-
-
Pinti, M.1
Gibellini, L.2
De Biasi, S.3
Nasi, M.4
Roat, E.5
-
14
-
-
18444390287
-
Transmission of cell stress from endoplasmic reticulum to mitochondria: Enhanced expression of Lon protease
-
DOI 10.1083/jcb.200108103
-
Hori O, Ichinoda F, Tamatani T, Yamaguchi A, Sato N et al. (2002) Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. J Cell Biol 157: 1151-1160. doi:10.1083/jcb. 200108103. PubMed: 12082077. (Pubitemid 34847786)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.7
, pp. 1151-1160
-
-
Hori, O.1
Ichinoda, F.2
Tamatani, T.3
Yamaguchi, A.4
Sato, N.5
Ozawa, K.6
Kitao, Y.7
Miyazaki, M.8
Harding, H.P.9
Ron, D.10
Tohyama, M.11
Stern, D.M.12
Ogawa, S.13
-
15
-
-
58849111392
-
Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins
-
doi:10.1111/j.1742-4658.2008.06847.x. PubMed: 19154341
-
Guillon B, Bulteau AL, Wattenhofer-Donzé M, Schmucker S, Friguet B et al. (2009) Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins. FEBS J 276: 1036-1047. doi:10.1111/j.1742-4658.2008.06847.x. PubMed: 19154341.
-
(2009)
FEBS J
, vol.276
, pp. 1036-1047
-
-
Guillon, B.1
Bulteau, A.L.2
Wattenhofer-Donzé, M.3
Schmucker, S.4
Friguet, B.5
-
16
-
-
34547117627
-
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance
-
DOI 10.1074/jbc.M611540200
-
Lu B, Yadav S, Shah PG, Liu T, Tian B et al. (2007) Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance. J Biol Chem 282: 17363-17374. doi:10.1074/jbc.M611540200. PubMed: 17420247. (Pubitemid 47100268)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.24
, pp. 17363-17374
-
-
Lu, B.1
Yadav, S.2
Shah, P.G.3
Liu, T.4
Tian, B.5
Pukszta, S.6
Villaluna, N.7
Kutejova, E.8
Newlon, C.S.9
Santos, J.H.10
Suzuki, C.K.11
-
17
-
-
41249098355
-
The layered structure of human mitochondrial DNA nucleoids
-
PubMed: 18063578
-
Bogenhagen DF, Rousseau D, Burke S (2008) The layered structure of human mitochondrial DNA nucleoids. J Biol Chem 283: 3665-3675. PubMed: 18063578.
-
(2008)
J Biol Chem
, vol.283
, pp. 3665-3675
-
-
Bogenhagen, D.F.1
Rousseau, D.2
Burke, S.3
-
18
-
-
0033572319
-
Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes
-
Klaes R, Woerner SM, Ridder R, Wentzensen N, Duerst M et al. (1999) Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes. Cancer Res 59: 6132-6136. PubMed: 10626803. (Pubitemid 30035633)
-
(1999)
Cancer Research
, vol.59
, Issue.24
, pp. 6132-6136
-
-
Klaes, R.1
Woerner, S.M.2
Ridder, R.3
Wentzensen, N.4
Duerst, M.5
Schneider, A.6
Lotz, B.7
Melsheimer, P.8
Von Knebel, D.M.9
-
19
-
-
0034730196
-
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
-
doi:10.1073/pnas.170093297. PubMed: 10944189
-
Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S et al. (2000) The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci U S A 97: 10002-10007. doi:10.1073/pnas.170093297. PubMed: 10944189.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10002-10007
-
-
Duensing, S.1
Lee, L.Y.2
Duensing, A.3
Basile, J.4
Piboonniyom, S.5
-
20
-
-
77149149956
-
The biological properties of E6 and E7 oncoproteins from human papillomaviruses
-
doi:10.1007/s11262-009-0412-8. PubMed: 19838783
-
Ghittoni R, Accardi R, Hasan U, Gheit T, Sylla B et al. (2010) The biological properties of E6 and E7 oncoproteins from human papillomaviruses. Virus Genes 40: 1-13. doi:10.1007/s11262-009-0412-8. PubMed: 19838783.
-
(2010)
Virus Genes
, vol.40
, pp. 1-13
-
-
Ghittoni, R.1
Accardi, R.2
Hasan, U.3
Gheit, T.4
Sylla, B.5
-
21
-
-
84865189303
-
Hedgehog pathway regulators influence cervical cancer cell proliferation, survival and migration
-
PubMed: 22820185
-
Samarzija I, Beard P (2012) Hedgehog pathway regulators influence cervical cancer cell proliferation, survival and migration. Biochem Biophys Res Commun, 425: 64-9. PubMed: 22820185.
-
(2012)
Biochem Biophys Res Commun
, vol.425
, pp. 64-69
-
-
Samarzija, I.1
Beard, P.2
-
22
-
-
12744268421
-
Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis
-
doi:10.1074/mcp.M400094-MCP200. PubMed: 15501831
-
Fukada K, Zhang F, Vien A, Cashman NR, Zhu H (2004) Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis. Mol Cell Proteomics 3: 1211-1223. doi:10.1074/mcp.M400094-MCP200. PubMed: 15501831.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 1211-1223
-
-
Fukada, K.1
Zhang, F.2
Vien, A.3
Cashman, N.R.4
Zhu, H.5
-
23
-
-
0033036242
-
Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease
-
DOI 10.1016/S0014-5793(99)00058-7, PII S0014579399000587
-
Luciakova K, Sokolikova B, Chloupkova M, Nelson BD (1999) Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease. FEBS Lett 444: 186-188. doi:10.1016/S0014-5793(99)00058-7. PubMed: 10050756. (Pubitemid 29092799)
-
(1999)
FEBS Letters
, vol.444
, Issue.2-3
, pp. 186-188
-
-
Luciakova, K.1
Sokolikova, B.2
Chloupkova, M.3
Nelson, B.D.4
-
24
-
-
78449276275
-
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints
-
doi:10.1111/j.1349-7006.2010.01701.x. PubMed: 21077998
-
Wang HM, Cheng KC, Lin CJ, Hsu SW, Fang WC et al. (2010) Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints. Cancer Sci 101: 2612-2620. doi:10.1111/j.1349-7006.2010.01701.x. PubMed: 21077998.
-
(2010)
Cancer Sci
, vol.101
, pp. 2612-2620
-
-
Wang, H.M.1
Cheng, K.C.2
Lin, C.J.3
Hsu, S.W.4
Fang, W.C.5
-
25
-
-
84859585597
-
The mitochondrial ATP-dependent Lon protease: A novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives
-
doi:10.1182/blood-2011-02-340075. PubMed: 22323447
-
Bernstein SH, Venkatesh S, Li M, Lee J, Lu B et al. (2012) The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives. Blood 119: 3321-3329. doi:10.1182/blood-2011-02-340075. PubMed: 22323447.
-
(2012)
Blood
, vol.119
, pp. 3321-3329
-
-
Bernstein, S.H.1
Venkatesh, S.2
Li, M.3
Lee, J.4
Lu, B.5
-
26
-
-
84455173253
-
Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix
-
doi:10.1074/jbc.M111.285197. PubMed: 22002062
-
Okumoto K, Kametani Y, Fujiki Y (2011) Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix. J Biol Chem 286: 44367-44379. doi:10.1074/jbc.M111.285197. PubMed: 22002062.
-
(2011)
J Biol Chem
, vol.286
, pp. 44367-44379
-
-
Okumoto, K.1
Kametani, Y.2
Fujiki, Y.3
-
27
-
-
84901491238
-
Mitochondrial matrix proteases as novel therapeutic targets in malignancy
-
([MedlinePgn:]) PubMed: 23770858
-
Goard CA, Schimmer AD (2013) Mitochondrial matrix proteases as novel therapeutic targets in malignancy. Oncogene: ([MedlinePgn:]) PubMed: 23770858.
-
(2013)
Oncogene
-
-
Goard, C.A.1
Schimmer, A.D.2
-
28
-
-
0029762950
-
Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon
-
DOI 10.1126/science.274.5284.103
-
Rep M, van Dijl JM, Suda K, Schatz G, Grivell LA et al. (1996) Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon. Science 274: 103-106. doi:10.1126/science.274.5284.103. PubMed: 8810243. (Pubitemid 26332734)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 103-106
-
-
Rep, M.1
Van Dijl, J.M.2
Suda, K.3
Schatz, G.4
Grivell, L.A.5
Suzuki, C.K.6
-
29
-
-
84866169183
-
Lon protease of Azorhizobium caulinodans ORS571 is required for suppression of reb gene expression
-
doi:10.1128/AEM.01039-12. PubMed: 22752172
-
Nakajima A, Aono T, Tsukada S, Siarot L, Ogawa T et al. (2012) Lon protease of Azorhizobium caulinodans ORS571 is required for suppression of reb gene expression. Appl Environ Microbiol 78: 6251-6261. doi:10.1128/AEM.01039-12. PubMed: 22752172.
-
(2012)
Appl Environ Microbiol
, vol.78
, pp. 6251-6261
-
-
Nakajima, A.1
Aono, T.2
Tsukada, S.3
Siarot, L.4
Ogawa, T.5
-
30
-
-
0036713692
-
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
-
DOI 10.1038/ncb836
-
Bota DA, Davies KJ (2002) Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat Cell Biol 4: 674-680. doi:10.1038/ncb836. PubMed: 12198491. (Pubitemid 34993703)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 674-680
-
-
Bota, D.A.1
Davies, K.J.A.2
-
31
-
-
77953269894
-
Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells
-
PubMed: 17584658
-
Xue X, Zhu YF, Mao JP (2007) Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells. NAN Fang Yi Ke da Xue Xue Bao 27: 870-874. PubMed: 17584658.
-
(2007)
NAN Fang Yi Ke Da Xue Xue Bao
, vol.27
, pp. 870-874
-
-
Xue, X.1
Zhu, Y.F.2
Mao, J.P.3
-
32
-
-
15744384860
-
Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
-
DOI 10.1016/j.freeradbiomed.2004.11.017
-
Bota DA, Ngo JK, Davies KJ (2005) Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic Biol Med 38: 665-677. doi:10.1016/j.freeradbiomed.2004.11.017. PubMed: 15683722. (Pubitemid 40416862)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.5
, pp. 665-677
-
-
Bota, D.A.1
Ngo, J.K.2
Davies, K.J.A.3
-
33
-
-
84859864623
-
Upsides and downsides of reactive oxygen species for cancer: The roles of reactive oxygen species in tumorigenesis, prevention, and therapy
-
doi:10.1089/ars.2011.4414. PubMed: 22117137
-
Gupta SC, Hevia D, Patchva S, Park B, Koh W et al. (2012) Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy. Antioxid Redox Signal 16: 1295-1322. doi:10.1089/ars.2011.4414. PubMed: 22117137.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1295-1322
-
-
Gupta, S.C.1
Hevia, D.2
Patchva, S.3
Park, B.4
Koh, W.5
-
34
-
-
84879678155
-
Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species. Cell Death
-
Cheng CW, Kuo CY, Fan CC, Fang WC, Jiang SS et al. (2013) Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species. Cell Death. Drosophila Inf Service 4: e681.
-
(2013)
Drosophila Inf Service
, vol.4
-
-
Cheng, C.W.1
Kuo, C.Y.2
Fan, C.C.3
Fang, W.C.4
Jiang, S.S.5
-
35
-
-
79955759980
-
Organometallic iron(III)-salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation
-
doi:10.1371/journal.pone.0019049. PubMed: 21559503
-
Kim KK, Singh RK, Strongin RM, Moore RG, Brard L et al. (2011) Organometallic iron(III)-salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation. PLOS ONE 6: e19049. doi:10.1371/journal.pone.0019049. PubMed: 21559503.
-
(2011)
PLOS ONE
, vol.6
-
-
Kim, K.K.1
Singh, R.K.2
Strongin, R.M.3
Moore, R.G.4
Brard, L.5
-
36
-
-
84871962586
-
Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome
-
PubMed: 23220263
-
Erjavec N, Bayot A, Gareil M, Camougrand N, Nystrom T et al. (2013) Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome. Free Radic Biol Med, 56: 9-16. PubMed: 23220263.
-
(2013)
Free Radic Biol Med
, vol.56
, pp. 9-16
-
-
Erjavec, N.1
Bayot, A.2
Gareil, M.3
Camougrand, N.4
Nystrom, T.5
|