Platelet-rich plasma combined with agarose as a bioactive scaffold to enhance cartilage repair: An in vitro study

Journal of Biomaterials Applications

Volumn 28, Issue 7, 2014, Pages 1039-1050

  Yin, Zhaowei ^a   Yang, Xiaofei ^a   Jiang, Yiqiu ^a   Xing, Linzi ^b   Xu, Yang ^a   Lu, Yiming ^a   Ding, Peng ^a   Ma, Junxin ^a   Gui, Jianchao ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Department of Cardiology   (China)

Author keywords

agarose; cartilage repair; Platelet rich plasma; scaffold

Indexed keywords

AGAROSE; CARTILAGE REPAIR; PLATELET-RICH PLASMA; SCAFFOLD;

ANIMALS; BASE SEQUENCE; CARTILAGE, ARTICULAR; COLLAGEN; DNA; DNA PRIMERS; GLYCOSAMINOGLYCANS; MICROSCOPY, ELECTRON, SCANNING; PLATELET-RICH PLASMA; POROSITY; REAL-TIME POLYMERASE CHAIN REACTION; SEPHAROSE; SWINE; SWINE, MINIATURE; TISSUE SCAFFOLDS;

EID: 84894151831     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328213492573     Document Type: Article

References (48)

1. Buckwalter JA. Articular cartilage: injuries and potential for healing. J Orthop Sports Phys Ther. 1998 ; 28 (4). 192-202
2. Karthikeyan S, Roberts S, Griffin D. Microfracture for acetabular chondral defects in patients with femoroacetabular impingement: results at second-look arthroscopic surgery. Am J Sports Med. 2012 ; 40 (12). 2725-2730
3. Hangody L, Kish G, Karpati Z, et al. Mosaicplasty for the treatment of articular cartilage defects: application in clinical practice. Orthopedics. 1998 ; 21 (7). 751-756
4. Peterson L, Minas T, Brittberg M, et al. Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Relat Res. 2000 ; (374). 212-234
5. Heymer A, Bradica G, Eulert J, et al. Multiphasic collagen fibre-PLA composites seeded with human mesenchymal stem cells for osteochondral defect repair: an in vitro study. J Tissue Eng Regen Med. 2009 ; 3 (5). 389-397
6. Lohan A, Marzahn U, El SK, et al. In vitro and in vivo neo-cartilage formation by heterotopic chondrocytes seeded on PGA scaffolds. Histochem Cell Biol. 2011 ; 136 (1). 57-69
7. Qi Y, Du Y, Li W, Dai X, Zhao T, Yan W. Cartilage repair using mesenchymal stem cell (MSC) sheet and MSCs-loaded bilayer PLGA scaffold in a rabbit model. Knee Surg Sports Traumatol Arthrosc. Epub ahead of print 30 October 2012. DOI: 10.1007/s00167-012-2256-3.
8. Hwang Y, Sangaj N, Varghese S. Interconnected macroporous poly(ethylene glycol) cryogels as a cell scaffold for cartilage tissue engineering. Tissue Eng Part A. 2010 ; 16 (10). 3033-3041
9. Colosi C, Costantini M, Barbetta A, et al. Morphological comparison of PVA scaffolds obtained by gas foaming and microfluidic foaming techniques. Langmuir. 2013 ; 29 (1). 82-91
10. Jiang J, Hao W, Li Y, Yao J, Shao Z, Li H, et al. Hydroxyapatite/ regenerated silk fibroin scaffold-enhanced osteoinductivity and osteoconductivity of bone marrow-derived mesenchymal stromal cells. Biotechnol Lett 2012; 35(4): 657-661.
11. Li Z, Zhang M. Chitosan-alginate as scaffolding material for cartilage tissue engineering. J Biomed Mater Res A. 2005 ; 75 (2). 485-493
12. Lee CR, Breinan HA, Nehrer S, et al. Articular cartilage chondrocytes in type I and type II collagen-GAG matrices exhibit contractile behavior in vitro. Tissue Eng. 2000 ; 6 (5). 555-565
13. Ingavle GC, Dormer NH, Gehrke SH, et al. Using chondroitin sulfate to improve the viability and biosynthesis of chondrocytes encapsulated in interpenetrating network (IPN) hydrogels of agarose and poly(ethylene glycol) diacrylate. J Mater Sci Mater Med. 2012 ; 23 (1). 157-170
14. Benya PD, Shaffer JD. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell. 1982 ; 30 (1). 215-224
15. Lee DA, Noguchi T, Frean SP, et al. The influence of mechanical loading on isolated chondrocytes seeded in agarose constructs. Biorheology. 2000 ; 37 (1-2). 149-161
16. Ng KW, Lima EG, Bian L, et al. Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A. 2010 ; 16 (3). 1041-1051
17. Ng KW, Wang CC, Mauck RL, et al. A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs. J Orthop Res. 2005 ; 23 (1). 134-141
18. Weisser J, Rahfoth B, Timmermann A, et al. Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose. Osteoarthritis Cartilage. 2001 ; 9: S48 - S54
19. Mazzocca AD, McCarthy MB, Chowaniec DM, et al. Platelet-rich plasma differs according to preparation method and human variability. J Bone Joint Surg Am. 2012 ; 94 (4). 308-316
20. Akeda K, An HS, Okuma M, et al. Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage. 2006 ; 1;14 (12). 1272-1280
21. Kutlu B, Tigli AR, Akman AC, et al. Platelet-rich plasma-loaded chitosan scaffolds: preparation and growth factor release kinetics. J Biomed Mater Res B Appl Biomater. 2013 ; 101 (1). 28-35
22. Rai B, Oest ME, Dupont KM, et al. Combination of platelet-rich plasma with polycaprolactone-tricalcium phosphate scaffolds for segmental bone defect repair. J Biomed Mater Res A. 2007 ; 81 (4). 888-899
23. Lippross S, Moeller B, Haas H, et al. Intraarticular injection of platelet-rich plasma reduces inflammation in a pig model of rheumatoid arthritis of the knee joint. Arthritis Rheum. 2011 ; 63 (11). 3344-3353
24. Park K, Huang J, Azar F, et al. Scaffold-free, engineered porcine cartilage construct for cartilage defect repair-in vitro and in vivo study. Artif Organs. 2006 ; 30 (8). 586-596
25. Hokugo A, Sawada Y, Hokugo R, et al. Controlled release of platelet growth factors enhances bone regeneration at rabbit calvaria. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 ; 104 (1). 44-48
26. Murray MM, Spindler KP, Abreu E, et al. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res. 2007 ; 25 (1). 81-91
27. Xie X, Wang Y, Zhao C, et al. Comparative evaluation of MSCs from bone marrow and adipose tissue seeded in PRP-derived scaffold for cartilage regeneration. Biomaterials. 2012 ; 33 (29). 7008-7018
28. Gaissmaier C, Koh JL, Weise K. Growth and differentiation factors for cartilage healing and repair. Injury. 2008 ; 39: S88 - S96
29. Guerne PA, Sublet A, Lotz M. Growth factor responsiveness of human articular chondrocytes: distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts. J Cell Physiol. 1994 ; 158 (3). 476-484
30. Fortier LA, Mohammed HO, Lust G, et al. Insulin-like growth factor-I enhances cell-based repair of articular cartilage. J Bone Joint Surg Br. 2002 ; 84 (2). 276-288
31. Longobardi L, O'Rear L, Aakula S, et al. Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. J Bone Miner Res. 2006 ; 21 (4). 626-636
32. Bujia J, Sittinger M, Wilmes E, et al. Effect of growth factors on cell proliferation by human nasal septal chondrocytes cultured in monolayer. Acta Otolaryngol. 1994 ; 114 (5). 539-543
33. Chopra R, Anastassiades T. Specificity and synergism of polypeptide growth factors in stimulating the synthesis of proteoglycans and a novel high molecular weight anionic glycoprotein by articular chondrocyte cultures. J Rheumatol. 1998 ; 25 (8). 1578-1584
34. Wu W, Chen F, Liu Y, Ma Q, Mao T. Autologous injectable tissue-engineered cartilage by using platelet-rich plasma: experimental study in a rabbit model. J Oral Maxillofac Surg 2007; 65(10): 1951-1957.
35. Ng KW, Lima EG, Bian L, O'Conor CJ, Jayabalan PS, Stoker AM, et al. Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A 2010; 16(3): 1041-1051.
36. Goldring MB. Articular cartilage degradation in osteoarthritis. HSS J 2012; 8(1): 7-9.
37. Boopalan PR, Arumugam S, Livingston A, Mohanty M, Chittaranjan S. Pulsed electromagnetic field therapy results in healing of full thickness articular cartilage defect. Int Orthop 2011; 35(1): 143-148.
38. Drengk A, Zapf A, Sturmer EK, Sturmer KM, Frosch KH. Influence of platelet-rich plasma on chondrogenic differentiation and proliferation of chondrocytes and mesenchymal stem cells. Cells Tissues Organs 2009; 189(5): 317-326.
39. Enders JT, Otto TJ, Peters HC, Wu J, Hardouin S, Moed BR, et al. A model for studying human articular cartilage integration in vitro. J Biomed Mater Res A 2010; 94(2): 509-514.
40. Kruger JP, Hondke S, Endres M, Pruss A, Siclari A, Kaps C. Human platelet-rich plasma stimulates migration and chondrogenic differentiation of human subchondral progenitor cells. J Orthop Res 2012; 30(6): 845-852.
41. Graziani F, Ivanovski S, Cei S, Ducci F, Tonetti M, Gabriele M. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Implants Res 2006; 17(2): 212-219.
42. Pillitteri D, Bassus S, Boller K, Mahnel R, Scholz T, Westrup D, et al. Thrombin-induced interleukin 1beta synthesis in platelet suspensions: impact of contaminating leukocytes. Platelets 2007; 18(2): 119-127.
43. El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M, et al. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol 2007; 78(4): 661-669.
44. Borregaard N, Sorensen OE, Theilgaard-Monch K. Neutrophil granules: A library of innate immunity proteins. Trends Immunol 2007; 28(8): 340-345.
45. Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol 1997; 24(2): 365-371.
46. Riyazi N, Slagboom E, de Craen AJ, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, et al. Association of the risk of osteoarthritis with high innate production of interleukin-1beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation. Arthritis Rheum 2005; 52(5): 1443-1450.
47. McCarrel TM, Minas T, Fortier LA. Optimization of leukocyte concentration in platelet-rich plasma for the treatment of tendinopathy. J Bone Joint Surg Am 2012; 94(19):e141-e143.
48. Hardingham T, Tew S, Murdoch A. Tissue engineering: chondrocytes and cartilage. Arthritis Res 2002; 4 Suppl 3: S63-S68.