Novel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activities

ACS Medicinal Chemistry Letters

Volumn 5, Issue 2, 2014, Pages 108-112

  Miranda, Daniela ^a   Capela, Rita ^a   Albuquerque, Ineîs S ^b   Meireles, Patrícia ^b   Paiva, Isa ^c   Nogueira, Fátima ^c   Amewu, Richard ^d   Gut, Jiri ^e   Rosenthal, Philip J ^e   Oliveira, Rudi ^a   Mota, Maria M ^b   Moreira, Rui ^a   Marti, Francesc ^d   Prudeîncio, Miguel ^b   O'Neill, Paul M ^d   Lopes, Francisca ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^c INSTITUTO DE HIGIENE E MEDICINA TROPICAL   (Portugal)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antimalarials; endoperoxide; P. berghei; sporogonic cycle

Indexed keywords

ENDOPEROXIDE; PRIMAQUINE; TETRAOXANE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOPHELES GAMBIAE; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIVER MICROSOME; MALARIA CONTROL; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; PRIORITY JOURNAL;

EID: 84894075620     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml4002985     Document Type: Article

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