Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations

Journal of Medical Genetics

Volumn 51, Issue 2, 2014, Pages 98-107

  Brohet, Richard M ^a,b   Velthuizen, Maria E ^c,d   Hogervorst, F B L ^a   Meijers Heijboer, Hanne E ^e,f   Seynaeve, C ^e   Collée, Margriet J ^e   Verhoef, S ^a   Ausems, M G E M ^d   Hoogerbrugge, Nicoline ^g   Van Asperen, C J ^h   García, Encarna Gómez ⁱ   Menko, Fred ^f   Oosterwijk, J C ^j   Devilee, P ^h   van't Veer, Laura J ^k   Van Leeuwen, F E ^a   Easton, Douglas F ^l   Rookus, M A ^a   Antoniou, Antonis C ^l   Schmidt, M K ^a   De Lange, J L ^a   Collee J M ^e   Van Den Ouweland, A M W ^e   Hooning, M J ^e   Van Deurzen, C H M ^e   Wijnen, J T ^h   Tollenaar, R A E M ^h   Van Cronenburg, T C T E F ^h   Kets, C M ^g   Mensenkam, A R ^g   Van Der Luij, R B ^d   Aalfs, C M ^m   Van Os, T A M ^m   Gille, J J P ^f   Waisfisz, Q ^f   Gomez Garcia E B ⁱ   Blok, M J ⁱ   Van Der Hout, A H ^j   Mourits, M J ^j   De Bock, G H ^j   Vasen, H F A ^c   more..

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b Infection and Immunology   (Netherlands)

^c Foundation for the Detection of Hereditary Tumours   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^g RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^h LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁱ MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^j UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^k UNIVERSITY OF CALIFORNIA   (United States)

^l UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^m ACADEMIC MEDICAL CENTER   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BIRTH; BREAST CANCER; CANCER PREVENTION; CANCER RISK; CANCER SURGERY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FAMILY HISTORY; FEMALE; FRAMESHIFT MUTATION; GENE MUTATION; GENETIC HETEROGENEITY; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MASTECTOMY; MIDDLE AGED; OVARIECTOMY; OVARY CANCER; PEDIGREE; PRIORITY JOURNAL; SEGREGATION ANALYSIS; YOUNG ADULT;

CANCER: BREAST; CLINICAL GENETICS; GENETIC EPIDEMIOLOGY; ONCOLOGY;

ADULT; AGE DISTRIBUTION; AGE OF ONSET; AGED; COHORT STUDIES; FEMALE; FOUNDER EFFECT; GENES, BRCA1; GENES, BRCA2; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HUMANS; MIDDLE AGED; MUTATION; NETHERLANDS; PEDIGREE; RISK; YOUNG ADULT;

EID: 84894064693     PISSN: 00222593     EISSN: 14686244     Source Type: Journal    
DOI: 10.1136/jmedgenet-2013-101974     Document Type: Article

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