Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Gareth, D Gareth ^a,b   Shenton, Andrew ^a   Woodward, Emma ^c   Lalloo, Fiona ^a   Howell, Anthony ^b,d   Maher, Eamonn R ^c  

^a ST MARY S HOSPITAL   (United Kingdom)

^b WYTHENSHAWE HOSPITAL   (United Kingdom)

^c UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^d CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGE; AGED; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER RISK; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; FAMILIAL CANCER; FAMILY; FEMALE; GENE MUTATION; GENETIC RISK; GENETIC SERVICE; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MASTECTOMY; OVARIECTOMY; OVARY CANCER; PENETRANCE; RELATIVE; RISK REDUCTION; STATISTICAL SIGNIFICANCE; BREAST TUMOR; FAMILY HEALTH; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; MIDDLE AGED; MUTATION; OVARY TUMOR; PROSPECTIVE STUDY; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; FAMILY HEALTH; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GERM-LINE MUTATION; HUMANS; MIDDLE AGED; OVARIAN NEOPLASMS; PENETRANCE; PROSPECTIVE STUDIES;

EID: 71049170380     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-155     Document Type: Article

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